Medical Research Articles Published in June 2012

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06/04/2012
Abstract 204: Molecular function of the RNA binding protein EWS in RNA processing Cancer Research
06/04/2012
Abstract 203: Hotair, a long non-coding RNA, exhibits pro-oncogenic activity in pancreatic cancer Cancer Research
06/04/2012
Abstract 202: Expressional alterations in functional ultra-conserved non-coding RNAs in response to ATRA-induced differentiation and changes in MYCN levels in neuroblastoma cells Cancer Research
06/04/2012
Abstract 201: DD3/PCA3 non-coding RNA regulates prostate cancer cell survival and modulates AR signaling Cancer Research
06/04/2012
Abstract 200: A transcribed BRCA1 pseudogene regulates gene expression and promotes breast cancer cell proliferation. Cancer Research
06/04/2012
Abstract 199: Noncoding RNAs of the 8q24 locus Cancer Research
06/04/2012
Abstract 198: Identification of differentially expressed microRNAs and other non-coding RNAs in ependymomas Cancer Research
06/04/2012
Abstract 197: Epigenetic regulation of miRNA expression in osteosarcoma Cancer Research
06/04/2012
Abstract 196: A real-time PCR based long noncoding RNA profiler for cancer research Cancer Research
06/04/2012
Abstract 195: The tumor cell compartment holds the unfavorable prognostic value of miR-21 in gliomas Cancer Research
06/04/2012
Abstract 194: MicroRNA-1 induces apoptosis by targeting prothymosin alpha in nasopharyngeal carcinoma cells Cancer Research
06/04/2012
Abstract 193: Prognostic impact of miR-146 polymorphism in patients with resected colorectal cancer Cancer Research
06/04/2012
Abstract 192: MiR-34c has an anti-apoptotic role in non-small-cell lung carcinoma Cancer Research
06/04/2012
Abstract 191: Subclassification of oral cancers using a miRNA-based combinatorial approach Cancer Research
06/04/2012
Abstract 190: Long noncoding RNA XY11-10-11 regulates proliferation and migration of esophageal adenocarcinoma cells Cancer Research
06/04/2012
Abstract 189: miRNAs regulating members of SLC transporter family genes in penile carcinomas Cancer Research
06/04/2012
Abstract 188: EphrinA1 induces microRNA-302b expression in malignant mesothelioma cells and suppresses tumor growth via repression of Mcl-1 gene Cancer Research
06/04/2012
Abstract 187: Down-regulation of microRNA34 induces cell proliferation and invasion of human mesothelial cells Cancer Research
06/04/2012
Abstract 186: High-throughput microRNA (miRNAs) arrays unravel the prognostic role of miR211 in pancreatic cancer Cancer Research
06/04/2012
Abstract 185: Alteration of microRNA expression profiles in HPV-associated squamous cell carcinoma of the head and neck (SCCHN) Cancer Research
06/04/2012
Abstract 184: Breed-associated differential microRNA expression in canine osteosarcoma Cancer Research
06/04/2012
Abstract 183: BRAF oncogene induces miR-17-92 cluster in thyroid cells and iodine counteracts this effect Cancer Research
06/04/2012
Abstract 182: Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by down-regulating RhoC and FZD4 Cancer Research
06/04/2012
Abstract 181: MIR-18b decreases self-renewal of glioblastoma cancer stem-like cells through targeting NOTCH2, NEDD9, and MEKK1 Cancer Research
06/04/2012
Abstract 179: MicroRNA-29c functions as a tumor suppressor by direct targeting endogenous SIRT1 in hepatocarcinogenesis Cancer Research
06/04/2012
Abstract 178: A novel mechanism of hypoxia mediated cell cycle dysregulation: miR-134 targets CDKN2A Cancer Research
06/04/2012
Abstract 177: MiR-10b promotes migration and invasion in pancreatic cancer cells Cancer Research
06/04/2012
Abstract 176: Kinase activity of tumor-derived exosomes as a potential biomarker for response to treatment Cancer Research
06/04/2012
Abstract 175: Atypical PKC knockdown alters TGF{beta} signaling potential Cancer Research
06/04/2012
Abstract 174: Keratin 8 and 18 knockdown increases cisplatin-induced apoptosis and invasive potential through claudin1/PI3K/NFkB up-regulation in epithelial carcinoma cells Cancer Research
06/04/2012
Abstract 173: Targeting the MUC1-C oncoprotein blocks activation of FLT-3/ITD and induces death of acute myeloid leukemia cells Cancer Research
06/04/2012
Abstract 172: Utility of retinoid treatment in the reversion of the malignant phenotype of mammary tumors with alterations in the expression of protein kinase C (PKC) isoforms Cancer Research
06/04/2012
Abstract 171: EGCG enhances the therapeutic potential of gemcitabine and CP690550 (Tasocitinib) by inhibiting STAT3 signaling pathway in human pancreatic cancer cells Cancer Research
06/04/2012
Abstract 170: Thymoquinone-mediated suppression of NF- {alpha}B activity causes inhibition of cell viability and induces apoptosis in activated B-cell sub-type of diffuse large B-cell lymphoma Cancer Research
06/04/2012
Abstract 169: Inhibition of focal adhesion kinase suppresses gastrin-releasing peptide receptor-mediated liver metastasis in neuroblastoma Cancer Research
06/04/2012
Abstract 168: Cytokine signaling through the JAK2/STAT3 pathway is a viable therapeutic target in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 167: Myricetin suppresses UVB-induced photoaging, skin cancer, and angiogenesis by targeting multiple kinases Cancer Research
06/04/2012
Abstract 166: A novel therapeutic approach for triple negative breast cancer Cancer Research
06/04/2012
Abstract 165: The anticarcinogenic effects of melatonin on inhibition of fatty acid transport and 13-HODE production in HT29 human colorectal cancer occurs via receptor-mediated signal transduction Cancer Research
06/04/2012
Abstract 164: High throughput homogenous bioluminescent assays for monitoring the concentrations of AMP, ADP and ATP Cancer Research
06/04/2012
Abstract 163: Common food additive carrageenan activates wnt signaling pathway in mouse colon and human colonic epithelial cells Cancer Research
06/04/2012
Abstract 162: Biomarker identification of residual triple negative breast cancer (TNBC) after standard neoadjuvant chemotherapy (NCT) Cancer Research
06/04/2012
Abstract 161: The role of mTOR in the cisplatin resistant phenotype in ovarian cancer lineage Cancer Research
06/04/2012
Abstract 160: Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells Cancer Research
06/04/2012
Abstract 159: Macrophage Migration Inhibitory Factor (MIF) enhances proliferation and expression of tumorigenic cytokines in a bladder cancer cell line Cancer Research
06/04/2012
Abstract 158: Cyclopamine, an inhibitor of hedgehog signaling, induces monocytic differentiation of acute myelogenous leukemia cells Cancer Research
06/04/2012
Abstract 157: Optimizing the flow cytometric analysis of cell signaling in heterogeneous samples Cancer Research
06/04/2012
Abstract 156: Screening and characterization of inhibitors of G-protein coupled receptor kinase GRK6 as potential therapeutics for multiple myeloma Cancer Research
06/04/2012
Abstract 155: Mining for novel JAK3 mutations in pediatric patients with acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 154: [6]-Shogaol inhibits cell growth and induces apoptosis in non-small-cell lung cancer (NSCLC) cells by regulating multiple targets Cancer Research
06/04/2012
Abstract 153: Honokiol, a promising small molecular weight natural agent, activates AMP-activated protein kinase in breast cancer cells via LKB1-dependent pathway and inhibits breast carcinogenesis Cancer Research
06/04/2012
Abstract 152: Nicotine inhibits the therapeutic effects of gemcitabine in pancreatic cancer cells in vitro and in a mouse xenograft model Cancer Research
06/04/2012
Abstract 151: Advancing pathway analysis using bioluminescent reporters Cancer Research
06/04/2012
Abstract 150: Combined treatment effects of {gamma}-tocotrienol with PPAR{gamma} agonists and antagonists on MCF-7 and MDA-MB-231 breast cancer cell growth in culture Cancer Research
06/04/2012
Abstract 1866: Genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small cell lung cancer Cancer Research
06/04/2012
Abstract 1864: Role of store-operated Ca2+ entry in proliferation and cell cycle in melanoma Cancer Research
06/04/2012
Abstract 1863: The multifunconal role of B7-H3 in metastasis and drug resistance Cancer Research
06/04/2012
Abstract 1862: NY-ESO-1 and clinicopathological features in ovarian cancer Cancer Research
06/04/2012
Abstract 1861: EPHB4 as a potential therapeutic target for esophageal cancer Cancer Research
06/04/2012
Abstract 1860: Protective effect of catechol-O-methyltransferase-mediated 4-hydroxyestradiol metabolism in human renal cell cancers Cancer Research
06/04/2012
Abstract 1857: Intracellular protein GP128 is a novel tumor angiogenesis marker on gastric cancer cell lines and GI tissues: Ectopic expression on the cell surface defined by MS38-2.1 mAb Cancer Research
06/04/2012
Abstract 1856: Functional analysis of annexin A4 and the implication in ovarian clear cell adenocarcinoma (OCCA) phenotypes Cancer Research
06/04/2012
Abstract 1855: Jab1/CSN5 a negative regulator of p27 plays a role in the pathogenesis and cisplatin sensitivity of nasopharyngeal carcinoma Cancer Research
06/04/2012
Abstract 1852: Identification of the UV-inducible RNA binding protein hnRNP A18 as a new target for melanoma progression Cancer Research
06/04/2012
Abstract 1849: Identification and functional analysis of SHISA2 overexpressed in prostate cancer Cancer Research
06/04/2012
Abstract 1848: Expression of an androgen transporter, organic anion transporting polypeptide 1B3, impacts progression and treatment of prostate cancer Cancer Research
06/04/2012
Abstract 1846: Cyr61 a therapeutic target for breast carcinomas Cancer Research
06/04/2012
Abstract 1845: ADAM10: A new player in breast cancer progression Cancer Research
06/04/2012
Abstract 1844: CD43 normally expressed on the surface of leukocytes is expressed in the cytoplasm and nucleus of breast cancer and is a novel therapeutic target Cancer Research
06/04/2012
Abstract 1842: PHT-782 an inhibitor of the KRAS signaling nanocluster protein CNKSR1 blocks mutant KRAS signaling and cell growth but does not inhibit wild type KRAS cell growth Cancer Research
06/04/2012
Abstract 1840: SapC-DOPS nanovesicles: Acidic lipid domain-targeted agents for cancer therapy Cancer Research
06/04/2012
Abstract 1839: Phosphodiesterase 4 regulates lung tumor growth through HIF regulation, proliferation, and angiogenesis Cancer Research
06/04/2012
Abstract 1836: p38{alpha} MAPK interacts with and inhibits RAR{alpha}: Suppression of the kinase enhances the therapeutic activity of retinoids in acute myeloid leukemia cells Cancer Research
06/04/2012
Abstract 1834: Targeting ABC transporters in cancer through small molecule inhibitors Cancer Research
06/04/2012
Abstract 1833: A large-scale synthetic lethal RNAi screening identifies unique sensitizing targets for anti-inflammatory CDDO-Me in metastatic melanoma Cancer Research
06/04/2012
Abstract 1832: Anti-nicastrin monoclonal antibodies as therapeutics for invasive breast cancer: Characterization and function Cancer Research
06/04/2012
Abstract 1831: Selective inhibitors of nuclear export (SINE) induce multiple tumor suppressor proteins (TSP) activity and show single agent antitumor effect and synergy with Bcl-2 antagonist in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 1830: Both class I and class II histone deacetylases are required for proliferation and survival of human pancreatic cancer cells Cancer Research
06/04/2012
Abstract 1829: Small molecule stabilization of the kRAS promoter G-quadruplex as a target for novel pancreatic cancer therapeutics Cancer Research
06/04/2012
Abstract 1828: Identification of MUC16/CA125-specific therapeutics through dual fluorescence high throughput screening Cancer Research
06/04/2012
Abstract 1827: Developing chemotherapeutics which selectively disable the actin cytoskeleton of tumor cells Cancer Research
06/04/2012
Abstract 1826: Anti-tumorigenic effects by targeted functional disruption of the Sin3 PAH-2 domain Cancer Research
06/04/2012
Abstract 1825: Novel small molecule CRM-1 inhibitor for Non Hodgkin's Lymphoma Cancer Research
06/04/2012
Abstract 1824: Functional characterization of DOG1 in Gastrointestinal Stromal Tumors (GIST) Cancer Research
06/04/2012
Abstract 1823: AZ20, a novel potent and selective inhibitor of ATR kinase with in vivo antitumour activity Cancer Research
06/04/2012
Abstract 1822: Novel potent inhibitor of Bcr-Abl mutated imatinib resistant chronic myeloid leukemia cell lines Cancer Research
06/04/2012
Abstract 1820: CDK3: A novel tumor-selective drug target involved in AP1 activation and transcriptional damage response Cancer Research
06/04/2012
Abstract 1819: A MUC1-C oncoprotein soluble decoy receptor effectively suppresses the growth of human breast cancer cells Cancer Research
06/04/2012
Abstract 1818: The Aurora B inhibitor ABT-348 is not susceptible to known resistance mechanisms of other Aurora B inhibitors Cancer Research
06/04/2012
Abstract 1815: CRM-1 as a potential therapeutic target in pancreatic cancer Cancer Research
06/04/2012
Abstract 1814: Claudin-3 and claudin-4 regulate sensitivity to cisplatin by controlling expression of the copper and cisplatin influx transporter CTR1 Cancer Research
06/04/2012
Abstract 1813: Evaluation of TBK1 as a novel cancer target in the K-Ras pathway Cancer Research
06/04/2012
Abstract 1811: Antitumor activity of lapatinib in combination with the dual mTORC1/2 inhibitor INK-128 in breast tumors resistant to anti-HER2 therapy Cancer Research
06/04/2012
Abstract 1810: Mechanistic studies of the dual Akt and JNK inhibitor Chaetoglobosin K: Effect on downstream pathways and AP-1 proteins in tumorigenic cells Cancer Research
06/04/2012
Abstract 1807: Characterization of a novel FLT3 inhibitor in AML cell lines Cancer Research
06/04/2012
Abstract 1805: Comparative analysis of 3 rapalogues, everolimus, temsirolimus and sirolimus, in hepatocarcinoma and renal cancer models resistant to VEGFR inhibitors Cancer Research
06/04/2012
Abstract 1804: Novel gold derivatives of thiosugars potently inhibit p-STAT3 and downregulate HIF-1{alpha} in ependymomas Cancer Research
06/04/2012
Abstract 1803: Discovery of novel B-Raf kinase inhibitor with potent orally anticancer activity Cancer Research
06/04/2012
Abstract 1802: IGF-1R inhibition as a novel therapeutic strategy for small cell lung cancer Cancer Research
06/04/2012
Abstract 1800: Targeted therapy using saracatinib adjunctive to castration inhibits progression to castration-resistant prostate cancer in a murine model Cancer Research
06/04/2012
Abstract 1799: Hypoxia-induced alterations of renal cell carcinoma cells and their modulation by tyrosine kinase inhibitors Cancer Research
06/04/2012
Abstract 1798: Identification of pan-Trk inhibitors for the treatment of Trk-driven cancers Cancer Research
06/04/2012
Abstract 1797: Preclinical evaluation of HM-018, a potent and selective JAK inhibitor in the treatment of myloproliferative disorders Cancer Research
06/04/2012
Abstract 1796: SAR302503: A Jak2 inhibitor with antitumor activity in solid tumor models Cancer Research
06/04/2012
Abstract 149: Antitumor effect of itraconazole on hematological malignant cells by suppression of Hedgehog signal transduction via inhibition of lipid raft formation Cancer Research
06/04/2012
Abstract 148: Glucocorticoid receptor-mediated cell survival following androgen receptor blockade in castrate-resistant prostate cancer Cancer Research
06/04/2012
Abstract 147: ER-{alpha}36 plays an important role in estrogen-dependent growth of gastric cancer cell line BGC823 Cancer Research
06/04/2012
Abstract 146: MicroRNA-150 expression induces differentiation of myeloid leukemias Cancer Research
06/04/2012
Abstract 145: MicroRNA-23b Expression is Regulated by VHL and effects on Glioma Cell survival and invasion Cancer Research
06/04/2012
Abstract 144: MicroRNA-190, regulated by estrogen receptor signaling, suppresses expression of the metastasis-promoting gene PAR-1 and is associated with breast cancer progression Cancer Research
06/04/2012
Abstract 143: CD24 induced miR-21 regulation is mainly mediated through Src, and both (CD24, Src) are post-transcriptionally downregulated by miR-34a Cancer Research
06/04/2012
Abstract 142: Tumor suppressor BRCA1 epigenetically controls oncogenic miRNA-155 Cancer Research
06/04/2012
Abstract 141: Epigenetic silencing of miR-122 in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 140: microRNA regulation of cell viability and drug response in cancer Cancer Research
06/04/2012
Abstract 139: The role of miRNAs in cyclooxygenase-2-mediated breast cancer progression Cancer Research
06/04/2012
Abstract 138: The effects of microRNA transfections on global patterns of gene expression are functionally coordinated Cancer Research
06/04/2012
Abstract 137: Molecular networks regulated by tumor suppressive microRNA-375 in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 136: Suppression of the uPA/uPAR system causes the overexpression of miR124 and suppresses stemness in glioma stem cells Cancer Research
06/04/2012
Abstract 135: Integrated analysis of cell signaling pathway-associated miRNAs using protein expression array data in NCI-60 cells Cancer Research
06/04/2012
Abstract 134: miRNA-708 suppresses prostate cancer growth through Akt2 signaling pathways Cancer Research
06/04/2012
Abstract 133: MiR-182 overexpression and ovarian high grade serous carcinoma Cancer Research
06/04/2012
Abstract 132: MicroRNA expression profiling in tumorigenic prostate cancer cells and tumor suppressive functions of let-7 Cancer Research
06/04/2012
Abstract 131: Hypomethylation of Alu repeat sequences permits activation of microRNAs in human colorectal cancer metastasis Cancer Research
06/04/2012
Abstract 130: Regulatory role of miR-29b in prostate cancer metastasis Cancer Research
06/04/2012
Abstract 129: miR-145 reduces tumor growth by regulating EGFR in human lung adenocarcinoma but not in Erlotinib-resistant cells Cancer Research
06/04/2012
Abstract 128: Exosomal miRNAs contribute to prostatic zinc homeostasis Cancer Research
06/04/2012
Abstract 1782: Human tumor explants are better predictors of clinical trial outcome than cell line xenografts for the KSP inhibitor ARRY-520 Cancer Research
06/04/2012
Abstract 1780: Synthesis and antitumor activity of proximicins A, B and C Cancer Research
06/04/2012
Abstract 1777: Antitumor effect of PM01183 in a human pancreatic adenocarcinoma orthotopic model Cancer Research
06/04/2012
Abstract 1776: Antitumor activity of Chk1 inhibitor LY2606368 as a single agent in SW1990 human pancreas orthotopic tumor model Cancer Research
06/04/2012
Abstract 1774: Dihydroartemisinin (DHA): A potent enhancer of PARP inhibitors and DNA-damaging agents activity in human tumor models Cancer Research
06/04/2012
Abstract 1772: Inhibition of DNA repair by the small molecule Chk1/Chk2 inhibitor PF-0477736 (Pfizer) in B-acute lymphoblastic leukemia (ALL) Cancer Research
06/04/2012
Abstract 1771: KOS-2464, a novel CRM1 inhibitor and a potential drug for multiple myeloma and leukemia Cancer Research
06/04/2012
Abstract 1764: Changes in apoptotic gene expression in human leukemia cells treated with the anticancer drug Laromustine Cancer Research
06/04/2012
Abstract 1763: A novel synthetic alkylating agent inducing DNA damages is associated with distinct DNA repair pathways Cancer Research
06/04/2012
Abstract 1762: Highly potent anti-cancer 'salan' Titanium(IV) complexes: Structure - function relationship Cancer Research
06/04/2012
Abstract 1761: Breast cancers with compromised DNA repair exhibit selective sensitivity to elesclomol-induced oxidative DNA damage Cancer Research
06/04/2012
Abstract 1760: Development of bisphosphonate prodrugs of doxorubicin for targeting bone metastases that are cleaved pH dependently or by cathepsin B Cancer Research
06/04/2012
Abstract 1758: A podophyllotoxin derivative, Adva-27a, is more potent at killing multi-drug resistant breast cancer cells than etoposide Cancer Research
06/04/2012
Abstract 1757: Elesclomol (STA-4783) is a potent inhibitor of topoisomerase II Cancer Research
06/04/2012
Abstract 1755: Pretargeted radioimmunotherapy of an anti-CEA bispecific antibody and 177Lu-labeled peptide: a phase I study in patients with advanced colorectal cancer Cancer Research
06/04/2012
Abstract 1753: Prospective stratification using gene expression arrays in a randomised trial of R-CHOP +/- Bortezomib in diffuse large B-cell lymphoma (DLBL): The UK NCRI REMoDL-B study, ISRCTN 51837425 Cancer Research
06/04/2012
Abstract 1752: A phase I/IIa, first time in human, open-label dose-escalation study of GSK2636771 in subjects with advanced solid tumors with PTEN deficiency Cancer Research
06/04/2012
Abstract 1749: Phase I/II clinical trial: Metronomic chemotherapy with cyclophosphamide (Cy) and celecoxib (Cel) in breast cancer patients progressing after standard chemotherapy Cancer Research
06/04/2012
Abstract 1746: The PREDICT (Personalised RNA Interference to Enhance the Delivery of Individualised Cytotoxic and Targeted Therapeutics) Approach to Biomarker Discovery in Renal Cell Carcinoma Cancer Research
06/04/2012
Abstract 1745: Translational medicine enables rapid early clinical development of AVL-292, a highly selective, orally available inhibitor of Bruton's tyrosine kinase, in a phase 1b clinical trial Cancer Research
06/04/2012
Abstract 1743: Phase 1 clinical trial of the base-excision repair inhibitor Methoxyamine-HCl (TRC102; MX) in combination with Temozolomide (TMZ) in patients with solid tumors Cancer Research
06/04/2012
Abstract 1739: The prevalence of KRAS, PIK3CA, and BRAF mutant subpopulations in tumors may be impacting the success of personalized cancer treatment Cancer Research
06/04/2012
Abstract 1738: Assay development for detecting cMET expression in circulating tumor cells (CTC), a potential patient tailoring marker for evaluation of cMET inhibitors Cancer Research
06/04/2012
Abstract 1737: Co-existence of positive MET FISH status with EGFR mutations signifies poor prognosis in lung adenocarcinoma Cancer Research
06/04/2012
Abstract 1736: Digital castPCR for direct detection of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in peripheral blood of lung cancer patients Cancer Research
06/04/2012
Abstract 1735: Evaluation of a novel flow cytometry-based system for the detection of circulating tumor cells Cancer Research
06/04/2012
Abstract 1732: DNA methylation profiling defines clinically relevant biological subsets of non-small cell lung cancer Cancer Research
06/04/2012
Abstract 1731: Correlation between XIAP, pAkt, and ATP7A expression and cisplatin resistance in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 1730: Expression of serum biomarkers related to epithelial-to-mesenchymal transition in non-small cell lung cancer recurrence Cancer Research
06/04/2012
Abstract 1729: An exploratory biomarker analysis evaluating the effect of the c-MET inhibitor tivantinib (ARQ 197) and erlotinib in NSCLC patients in a randomized, double-blinded phase 2 study Cancer Research
06/04/2012
Abstract 1728: Genetic variations in epidermal growth factor receptor pathway predict recurrence and response to chemotherapy in early stage non-small cell lung cancer Cancer Research
06/04/2012
Abstract 1726: A novel biomarker panel identifies the response to CDDP treatment in NSCLC patients Cancer Research
06/04/2012
Abstract 1725: Molecular determinants of Sorafenib sensitivity in renal and non small cell lung - Patient derived tumors engrafted in nude mice Cancer Research
06/04/2012
Abstract 1724: A gene expression profile test to resolve squamous cell carcinomas of head & neck from squamous cell carcinomas of the lung Cancer Research
06/04/2012
Abstract 1723: Can histologic patterns of pulmonary adenocarcinoma reflect histologic grade, one of the most important factors of cancer prognosis? Cancer Research
06/04/2012
Abstract 1721: Gene expression profiling of lung tumors and matched normal airways reveals common and disparate aberrant pathways in squamous cell carcinoma and adenocarcinoma development and potential markers for detection and targets for chemoprevention in early stage lung cancer Cancer Research
06/04/2012
Abstract 1720: Validation of a 15-gene prognostic signature in stage IB non small-cell lung cancer (NSCLC) Cancer Research
06/04/2012
Abstract 1718: Favorable clinical outcomes of pemetrexed treatment in anaplastic lymphoma kinase positive non-small-cell lung cancer patients were associated with low expression of thymidylate synthase in tumor Cancer Research
06/04/2012
Abstract 1717: Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy Cancer Research
06/04/2012
Abstract 1716: FGFR1 gene amplification predicts the antitumor response of FGFR inhibitor LY2874455 in human lung cancer cells Cancer Research
06/04/2012
Abstract 1715: High ALK gene copy number as a predictor of response to crizotinib in non-small cell lung cancer cell lines Cancer Research
06/04/2012
Abstract 1714: EZH2High and miR-101Low expressions are associated with chemoresistance and shorter survival in patients with lung adenocarcinoma who received adjuvant chemotherapy Cancer Research
06/04/2012
Abstract 1712: Ki67 index is an independent prognostic factor in pleural mesothelioma Cancer Research
06/04/2012
Abstract 1711: Expression patterns of the G protein-coupled receptor, GPRC5A, in human malignant pleural mesothelioma Cancer Research
06/04/2012
Abstract 1710: Quantitative 3D mapping of total choline in human breast cancer using high-speed MR spectroscopic imaging at 3T Cancer Research
06/04/2012
Abstract 1709: The effect of a XIAP inhibitor, embelin, on apoptosis of thyroid cancer cell lines Cancer Research
06/04/2012
Abstract 1708: LINE-1 methylation level is a molecular marker with little intra-patient heterogeneity in primary and synchronous metastatic colorectal cancer Cancer Research
06/04/2012
Abstract 1707: A real-time PCR assay for detecting EGFR mutations in formalin-fixed paraffin-embedded tissue (FFPET) specimens of non-small cell lung cancer (NSCLC) Cancer Research
06/04/2012
Abstract 1706: Comparison of automated and manual RNA isolation from stabilized peripheral blood samples (PBL) for expression analysis of colorectal cancer patients Cancer Research
06/04/2012
Abstract 1704: AC electrokinetic isolation of cell free high molecular weight DNA (CF-HMW DNA) from serum Cancer Research
06/04/2012
Abstract 1703: Discovery and validation of 20 novel breast cancer methylation biomarkers: A new workflow for methylation biomarker development Cancer Research
06/04/2012
Abstract 1701: Clinical significance of serum and tissue Dickkopf-1 in patients with gastric cancer Cancer Research
06/04/2012
Abstract 1700: The prognostic marker SHP-1 promoter 2 hypermethylation can detect lymph node micrometastases in early stage NSCLC Cancer Research
06/04/2012
Abstract 1699: Breast cancer protein markers in African Americans Cancer Research
06/04/2012
Abstract 1698: ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer - A comparative study of two monoclonal antibodies Cancer Research
06/04/2012
Abstract 1697: Gadd45A expression is high in luminal A and her2 human breast cancers, but frequently absent in triple negative breast cancers Cancer Research
06/04/2012
Abstract 1696: Targeting EVI1-overexpressing AML with darinaparsin Cancer Research
06/04/2012
Abstract 1695: Imaging of the interaction of pancreatic cancer and stellate cells during liver metastasis Cancer Research
06/04/2012
Abstract 1694: Imaging cell cycle progression in gastric cancer lymph node metastasis indicates large fraction of proliferating cancer cells Cancer Research
06/04/2012
Abstract 1693: Bevacizumab acutely decreases endothelium dependent vasodilation in healthy volunteers Cancer Research
06/04/2012
Abstract 1691: A primer dose followed by low-bolus dose schedule of tumor-targeting of S. typhimurium A1-R is effective for tumor-targeted therapy Cancer Research
06/04/2012
Abstract 1690: Tumor-educated macrophages promote tumor growth and peritoneal metastasis in an orthotopic nude mouse model of human pancreatic cancer Cancer Research
06/04/2012
Abstract 1689: Impact of pre-treatment body mass index on patients with head and neck cancer treated with radiation Cancer Research
06/04/2012
Abstract 1688: Relevance of mTOR pathway in prognosis of patients with urothelial carcinoma of the bladder Cancer Research
06/04/2012
Abstract 1686: Identification of potential prostate cancer biomarkers associated with TMPRSS2-ERG fusion and PTEN deletions Cancer Research
06/04/2012
Abstract 1684: The potential role of HER3 on HER2-driven biliary carcinogenesis and the possibility for targeted therapy with pertuzumab Cancer Research
06/04/2012
Abstract 1683: ALK F1174L kinase activity as driver of cell proliferation in neuroblastoma cell line models and neuroblastoma tumors Cancer Research
06/04/2012
Abstract 1682: Uncovering signals of somatic selection through whole exome and whole genome sequencing of lung adenocarcinoma Cancer Research
06/04/2012
Abstract 1679: Genome-wide methylation analysis in Barrett's esophagus and esophageal adenocarcinoma Cancer Research
06/04/2012
Abstract 1675: Effects of calcium and vitamin D on TGF{beta} and TGF{beta}1 expression in rectal mucosa of sporadic colorectal adenoma patients: A randomized controlled trial Cancer Research
06/04/2012
Abstract 1674: Two phase study of KCNJ1 polymorphisms, calcium, magnesium and colorectal adenoma risk, results from the Tennessee Colorectal Polyp Study Cancer Research
06/04/2012
Abstract 1673: BRAF mutation is associated with large, proximal sessile serrated polyps, but not with adenomas Cancer Research
06/04/2012
Abstract 1672: Population prevalence of consensus translocations in follicular and mantle cell lymphomas Cancer Research
06/04/2012
Abstract 1671: Inflammatory pathway genes may have stronger associations with hyperplastic polyps than with adenomas Cancer Research
06/04/2012
Abstract 1669: Discovery of nasopharyngeal carcinoma susceptible variants from whole genome imputation of genome-wide association study Cancer Research
06/04/2012
Abstract 1668: Understanding cancer associated SNPs in the TERT-CLPTM1L locus through population genetics Cancer Research
06/04/2012
Abstract 1667: Pathway analysis of bladder cancer genome-wide association study identifies several novel pathways involved in bladder cancer development Cancer Research
06/04/2012
Abstract 1665: High resolution genome profile in familial colorectal cases without mutations on mismatch repair genes Cancer Research
06/04/2012
Abstract 1664: A functional study of missense variants localized in the DNA binding domain of BRCA2 Cancer Research
06/04/2012
Abstract 1663: Mapping genes that predict treatment outcome in admixed populations Cancer Research
06/04/2012
Abstract 1659: Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer Cancer Research
06/04/2012
Abstract 1658: Post-GWAS genetic and functional studies for bladder cancer: An uncommon protective synonymous coding variant within the UGT1A6 gene explains the GWAS signal and affects cellular detoxification Cancer Research
06/04/2012
Abstract 1657: Genome-wide association study of lung cancer: Variation in TP63 gene confers the risk of lung adenocarcinoma Cancer Research
06/04/2012
Abstract 1655: Genome-wide association study for age at onset in breast cancer: results from the Seoul Breast Cancer Study Cancer Research
06/04/2012
Abstract 1654: The low-penetrance breast cancer risk allele MCS5A functions in T-cells through downregulation of the E3-ubiquitin ligase Fbxo10, to alter mammary epithelial cell differentiation Cancer Research
06/04/2012
Abstract 1653: Genetic variation in the vitamin D pathway and risk for colorectal cancer in African Americans Cancer Research
06/04/2012
Abstract 1650: Overview of the clinical ELLIPSE (ELucidating Loci Involved in Prostate cancer SuscEptibility) Consortium (CEC) Cancer Research
06/04/2012
Abstract 1649: Genome-wide association study of copy number variations in serous epithelial ovarian cancer susceptibility Cancer Research
06/04/2012
Abstract 1648: MICA variation and soluble MICA are possible prognostic biomarkers for HBV-induced hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 1647: Evaluation of breast cancer susceptibility loci in Chinese women from Singapore Cancer Research
06/04/2012
Abstract 1643: MicroRNA processing genes and implications for complex traits Cancer Research
06/04/2012
Abstract 1641: Concordance between mutations identified by bar-coded multiplexed sequencing of BRAF, NRAS, and KIT in formalin fixed (FFPE) tissue from melanoma patients using the Ion Torrent Personal Genome Machine (PGM) and a real-time PCR assay Cancer Research
06/04/2012
Abstract 1640: Unidentified genetic variants influence pancreatic cancer risk: An analysis of the PanScan genome-wide association study Cancer Research
06/04/2012
Abstract 1639: Chemopreventive and anti-inflammatory properties of "supercinnamaldehydes" - novel cinnamyl-based compounds Cancer Research
06/04/2012
Abstract 1636: Enhancement of cyclic GMP production by guanylate cyclase-C agonists delays progression of colitis into colon cancer though downregulation of pro-inflammatory cytokines Cancer Research
06/04/2012
Abstract 1635: Effect of dietary fish oil on rat colonic prostaglandin (PG) E2 metabolism Cancer Research
06/04/2012
Abstract 1634: Metabolomic profiling for early detection of colorectal neoplasia Cancer Research
06/04/2012
Abstract 1633: Chemopreventive efficacy of raloxifene, bexarotene and their combination on the progression of AOM-induced colon adenomas to adenocarcinomas in F344 rats Cancer Research
06/04/2012
Abstract 1632: Novel naproxen, resveratrol and sulforaphane (NRS) combinations demonstrate synergistic decrease in cell viability of human colon and pancreatic cancer cell lines Cancer Research
06/04/2012
Abstract 1631: Protection of colon carcinogenesis by estrogen receptor-beta may involve regulation of angiogenesis and invasion specific signaling molecules Cancer Research
06/04/2012
Abstract 1629: Dietary modification of colon and hepatic tumorigenesis Cancer Research
06/04/2012
Abstract 1627: Chloroquine-induced inhibition of Arginase-1 promotes the nuclear localization of p53 in colon cancer cell lines Cancer Research
06/04/2012
Abstract 1625: Curcumin induces expression of 15-hydroxyprostaglandin dehydrogenase in normal gastric mucosa RGM-1 cells: Possible involvement of AP-1 Cancer Research
06/04/2012
Abstract 1624: Black raspberries suppress phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway in carcinogen-induced esophageal cancer in rats Cancer Research
06/04/2012
Abstract 1623: Epigenetic regulation of tumor suppressor genes in esophageal cancer by berries Cancer Research
06/04/2012
Abstract 1622: Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells Cancer Research
06/04/2012
Abstract 1621: Potent anti-cancer effect of crocin against hepatocellular carcinoma: A preclinical study Cancer Research
06/04/2012
Abstract 1620: The protective effect of protein diets on experimentally induced hepatocellular carcinoma in Swiss albino mice Cancer Research
06/04/2012
Abstract 1618: Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand Cancer Research
06/04/2012
Abstract 1616: Preventive effects of EGCG on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db mice Cancer Research
06/04/2012
Abstract 1615: Anthocyanin-rich black raspberry extract negatively regulates stem cell related molecules, EMT, and pluripotency of pancreatic cancer stem cells Cancer Research
06/04/2012
Abstract 1614: Grape seed proanthocyanidins inhibit pancreatic cancer cell growth in vitro and in vivo through induction of apoptosis and inhibition of PI3K/Akt pathway Cancer Research
06/04/2012
Abstract 1612: Bitter melon juice induces apoptotic death of human pancreatic carcinoma cells Cancer Research
06/04/2012
Abstract 1611: EGCG inhibits growth of human pancreatic tumors orthotopically implanted in BALB/c Nude mice through activation of FKHRL1/FOXO3a transcription factor. Cancer Research
06/04/2012
Abstract 1610A: Chromatin modifying agents improve the anticancer activity of resveratrol in prostate cancer cells Cancer Research
06/04/2012
Abstract 1608: Silibinin synergizes with histone deacetylase (HDAC) inhibitors in upregulating E-cadherin expression in non-small lung cancer (NSCLC) cells Cancer Research
06/04/2012
Abstract 1606: Antitumor effects of vitamin D in a carcinogen-induced mouse model of lung cancer Cancer Research
06/04/2012
Abstract 1604: Treatment with Pequi (Caryocar brasiliense Camb) fruit pulp oil decrease the DNA damage caused by chemical carcinogenesis in experimental model of lung cancer. Cancer Research
06/04/2012
Abstract 1603: Relevance of myosmine in cigarette filter butt Cancer Research
06/04/2012
Abstract 1601: Ethanol promotes chemically induced oral cancer in mice through activation of the 5-lipoxygenase pathway of arachidonic acid metabolism Cancer Research
06/04/2012
Abstract 1600: Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by topical garcinol through inhibition of 5-lipoxygenase Cancer Research
06/04/2012
Abstract 1599: Grape seed proanthocyanidins inhibit UV-induced tolerogenic T-cell response through DNA repair-dependent functional activation of Langerhans cells Cancer Research
06/04/2012
Abstract 1598: Grape seed extract induces irreparable DNA damage causing G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells: Potential involvement of reactive oxygen species Cancer Research
06/04/2012
Abstract 1595: Comparing a topical-based curcumin to dietary curcumin in a skin cancer model Cancer Research
06/04/2012
Abstract 1594: Chemopreventive action of Piper nigrum on cell proliferation and apoptosis in skin papillomagenesis and its influence on the levels/activity of enzymes associated with xenobiotic metabolism and antioxidant status in Swiss albino mice Cancer Research
06/04/2012
Abstract 1591: Green tea polyphenols reactivate silenced tumor suppressor genes, p16INK4a and Cip1/p21, by reducing DNA methylation and increasing histone acetylation in UV-irradiated mouse skin and skin tumors Cancer Research
06/04/2012
Abstract 1589: Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3-K Cancer Research
06/04/2012
Abstract 1588: Synergistic apoptosis by combination of natural compound EGCG and resveratrol in head and neck cancer: Potential role for AKT-dependent signaling Cancer Research
06/04/2012
Abstract 1587: AMPK-mTOR axis as key target for chemoprevention of UV-induced skin cancer by the bioflavonoid apigenin Cancer Research
06/04/2012
Abstract 1586: Tumor regression in a 3-D melanoma model by the dietary flavonoid fisetin is associated with inhibition of Akt/mTOR signaling Cancer Research
06/04/2012
Abstract 1584: MHC-restricted phosphopeptides as broad-based immunotherapeutic targets for cancer Cancer Research
06/04/2012
Abstract 1582: Therapeutic vaccine for pancreatic cancer Cancer Research
06/04/2012
Abstract 1581: Identification of novel HLA-restricted T-cell epitopes specific for the breast cancer-associated tumor antigen NY-BR-1 Cancer Research
06/04/2012
Abstract 1580: LL-37-mediates tumor antigen-specific-T cell expansion and tumor regression Cancer Research
06/04/2012
Abstract 1795: Characterization of a novel series of potent, selective inhibitors of wild type and mutant/fusion anaplastic lymphoma kinase Cancer Research
06/04/2012
Abstract 1794: AP26113 is a dual ALK/EGFR inhibitor: Characterization against EGFR T790M in cell and mouse models of NSCLC Cancer Research
06/04/2012
Abstract 1793: Imatinib treatment for gefitinib-resistant lung cancer harboring epidermal growth factor receptor mutation Cancer Research
06/04/2012
Abstract 1792: The potential role of targeting HER1-4 in bladder cancer Cancer Research
06/04/2012
Abstract 1791: CO-1686, a novel mutant-selective EGFR inhibitor, overcomes T790M mediated resistance in Non-Small Cell Lung Cancer (NSCLC) Cancer Research
06/04/2012
Abstract 1790: The combination of MGCD265, a Met/VEGFR inhibitor in clinical development, and erlotinib potently inhibits tumor growth by altering multiple pathways including glycolysis Cancer Research
06/04/2012
Abstract 1787: The c-Met inhibitors EMD 1214063 and EMD 1204831 are effective in combination with EGFR and VEGF inhibitors in NSCLC models Cancer Research
06/04/2012
Abstract 1785: MET/VEGFR dual inhibition and prominent safety profile of TAS-115 are favorable for the combination with chemotherapeutic drugs Cancer Research
06/04/2012
Abstract 1784: Enhancement of hypoxia-activated prodrug TH-302 activity by Chk1 inhibition Cancer Research
06/04/2012
Abstract 1783: Trifluorothymidine incorporation into DNA strongly enforces the potential of TAS-102 and leads to remarkably prolonged survival of cancer patients Cancer Research
06/04/2012
Abstract 1348: CD38 regulates homing and engraftment in a mouse model of CLL Cancer Research
06/04/2012
Abstract 1346: Induction of multiple myeloma in a novel humanized bone marrow xenograft model does not depend on CD138 expression Cancer Research
06/04/2012
Abstract 1345: The use of optical imaging in a clinically relevant mouse intrafemoral model of leukaemia Cancer Research
06/04/2012
Abstract 1344: ZAP-70 enhances migration of malignant B lymphocytes toward lymphoid organs in a Burkitt lymphoma xenograft model Cancer Research
06/04/2012
Abstract 1340: A mouse model of metastatic intestinal cancers associated with Fbw7- and p53-loss Cancer Research
06/04/2012
Abstract 1339: The role of TNF-{alpha} in PGE2-induced tumorigenesis in gastric cancer mouse model Cancer Research
06/04/2012
Abstract 1338: Knockdown of CD24 prevents colorectal polyp formation in APCmin/CD24 double knockout transgenic mice Cancer Research
06/04/2012
Abstract 1337: Novel model of pancreatic cancer induced by smoking compound NNK Cancer Research
06/04/2012
Abstract 1335: Involvement of canonical Wnt/{beta}-catenin signaling pathway in pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 1334: Overexpression of claudin-1 induces Notch and Wnt signaling to regulate colon carcinogenesis Cancer Research
06/04/2012
Abstract 1333: Organ specific biomatrix scaffolds for ex vivo characterization of colorectal cancer metastases Cancer Research
06/04/2012
Abstract 1330: A reliable mouse model for hepatic metastasis of colorectal cancer Cancer Research
06/04/2012
Abstract 1329: Personalizing gastrointestinal cancer treatment by the utilization of TumorGraft™ technology Cancer Research
06/04/2012
Abstract 1328: Development of endoscopic ultrasound-guided fine-needle aspirate (EUS-FNA) derived pancreatic cancer cell lines from advanced stage cancers Cancer Research
06/04/2012
Abstract 1327: Macromolecular transport, collagen fiber morphology, and metastasis are influenced by the tumor growth location Cancer Research
06/04/2012
Abstract 1325: Loss of AGR2 results in compromised chief cell differentiation and preneoplastic metaplasia of stomach Cancer Research
06/04/2012
Abstract 1322: Autocrine c-met/HGF HCC patient derived xenograft (PDX) models for evaluating c-met inhibitors Cancer Research
06/04/2012
Abstract 1321: A novel prevention method against re-obstruction of titanium alloy stent for biliary malignancy using generation of hydroxyl radical under ultrasonic irradiation Cancer Research
06/04/2012
Abstract 1320: Over expression of HGF accelerates hepatitis B virus-induced liver carcinogenesis and hastens the malignancy of hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 1319: Establishment and characterization of fresh primary human colorectal tumor implants Cancer Research
06/04/2012
Abstract 1317: Dose-dependent effects of bevacizumab on human HCC xenografts Cancer Research
06/04/2012
Abstract 1316: N-acetyl-L-cysteine sensitizes pancreatic cancer therapy by targeting NF{kappa}B pathway: Translation into animal model Cancer Research
06/04/2012
Abstract 1314: Molecular profiling and characterization of patient-derived human pancreatic tumor xenograft models, and application for drug discovery and preclinical development of cancer therapeutics Cancer Research
06/04/2012
Abstract 1313: Mutually exclusive somatic mutations in WNT pathway medulloblastomas reveal a critical interaction between DDX3X and SMARCA4 Cancer Research
06/04/2012
Abstract 1311: Expression and activity of nuclear factor TOX3 in breast cancer Cancer Research
06/04/2012
Abstract 1310: SLC5A8 functions as a tumor suppressor through redistribution and depletion of survivin Cancer Research
06/04/2012
Abstract 1309: The lineage-specific transcription factor ASCL1 defines a subtype of non-small cell lung cancer with poor prognosis Cancer Research
06/04/2012
Abstract 1308: Achaete-scute homolog 1 (Ascl1) lineage in the lung gives rise to multiple cell types Cancer Research
06/04/2012
Abstract 1307: Heritable polymorphism predisposes to high expression of BAALC in cytogenetically normal acute myeloid leukemia (CN-AML) Cancer Research
06/04/2012
Abstract 1304: Specific MUC1 isoforms function to regulate gene expression and tumor growth in pancreatic cancer Cancer Research
06/04/2012
Abstract 1303: The Wilms' tumor gene, WT1, regulates E-cadherin expression and migration of prostate cancer cells. Cancer Research
06/04/2012
Abstract 1302: Effect of intestinal-specific Kaiso overexpression on the APC MIN/+ mouse colon cancer model Cancer Research
06/04/2012
Abstract 1300: Far upstream element binding proteins (FBP)-1 and FBP-2 in non-small cell lung cancer: Key factors regulating tumor cell proliferation, migration, and invasion Cancer Research
06/04/2012
Abstract 1299: PHD3 has a key role in survival and proliferation of renal carcinoma cells Cancer Research
06/04/2012
Abstract 1297: Engrailed-2 (EN2) represses the transcription of the CST6 tumour suppressor gene in prostate cancer Cancer Research
06/04/2012
Abstract 1295: Regulation of PAX2 activity by estradiol in breast cancer cells Cancer Research
06/04/2012
Abstract 1293: Galectin-3 facilitates the stability of p21 protein through carbohydrate recognition domain in prostate cancer cells Cancer Research
06/04/2012
Abstract 1291: Tumor growth inhibitory effect in EIF4B silenced in vitro and in vivo lung cancer models Cancer Research
06/04/2012
Abstract 1290: The ability of the transcription factor p63 to induce selected gene expression modules associated with mesenchymal to epithelial transition of prostate cells Cancer Research
06/04/2012
Abstract 1285: A functional liaison between E2F and aberrant ETS oncogenes Cancer Research
06/04/2012
Abstract 1284: Estrogen receptor alpha transcriptionally regulates p53 in MCF7 human breast cancer cells Cancer Research
06/04/2012
Abstract 1283: A study towards identification of plausible protein markers of squamous cell carcinoma Cancer Research
06/04/2012
Abstract 1280: Nano-scale phospho-proteomic analysis to define diagnostic signatures and biomarkers of therapeutic activity in cancer Cancer Research
06/04/2012
Abstract 1279: Proteomics signature of long-term versus short-term survival in glioblastoma Cancer Research
06/04/2012
Abstract 1278: Determining the proteomic changes that define progressor and non-progressor clear cell renal cell carcinoma Cancer Research
06/04/2012
Abstract 1277: Antigen-specific markers for paraneoplastic neurological syndromes obtained by proteomic analysis of patient immunoglobulins Cancer Research
06/04/2012
Abstract 1276: Application of high-throughput proteomics Micro-Western array in studying molecular mechanism of anticancer effect of liver X receptor agonists against human colon cancer cells Cancer Research
06/04/2012
Abstract 1275: Quantitative proteomic analysis of tumor growth associated proteins in cutaneous malignant melanoma Cancer Research
06/04/2012
Abstract 1272: MALDI imaging and next generation sequencing for dissecting prostate cancer heterogeneity Cancer Research
06/04/2012
Abstract 1271: Aberrant activation of Spleen Tyrosine Kinase in ovarian cancer identified through a global phosphorylation profiling of protein tyrosine kinases Cancer Research
06/04/2012
Abstract 1270: Identification and functional analysis of Pim-1 kinase substrates in prostate cancer Cancer Research
06/04/2012
Abstract 1269: Activation of diverse signaling pathways in pancreatic cancer revealed by phosphoproteomics Cancer Research
06/04/2012
Abstract 1267: Characterization of carcinoembryonic antigen (CEA) microheterogeneity: a case study considering N-linked glycoforms Cancer Research
06/04/2012
Abstract 1266: Glioma biomarker discovery by mass spectrometry Cancer Research
06/04/2012
Abstract 1264: Small volatile organic compounds extracted from advanced pancreatic cancer patient blood samples: Development towards a diagnostic method Cancer Research
06/04/2012
Abstract 1262: Simple western and NanoPro analysis of key EGF signaling cascade proteins Cancer Research
06/04/2012
Abstract 1261: A mesodissection system for accurate, rapid, and economical recovery of tissue from slide mounted tissue sections Cancer Research
06/04/2012
Abstract 1259: OncoScanTM FFPE Express 2.0: a cancer-focused whole-genome copy number platform requiring only 75 ng of input DNA from FFPE samples Cancer Research
06/04/2012
Abstract 1258: High-density protein lysate arrays: an essential tool in assessing antibody specificity for clinical applications Cancer Research
06/04/2012
Abstract 1255: A novel chip-based parallel transfection assay to evaluate paracrine cell interactions Cancer Research
06/04/2012
Abstract 1254: FAK activity regulates {alpha}v{beta}5 integrin and osteopontin expression to control breast and ovarian cancer anchorage-independent growth Cancer Research
06/04/2012
Abstract 1253: Fer is required for mammary tumorigenesis Cancer Research
06/04/2012
Abstract 1252: Cooperation between c-Met and focal adhesion kinase pathways in medulloblastoma and implications for therapy Cancer Research
06/04/2012
Abstract 1248: The use of nanoimmunoassay technology to predict response to insulin-like growth factor-1 receptor inhibition in head and neck squamous carcinoma Cancer Research
06/04/2012
Abstract 1246: ELK-1 regulates interferon-alpha8 expression via a polymorphic region in the interferon-alpha8 promoter associated with outcome of glioma patients Cancer Research
06/04/2012
Abstract 1243: RET and integrin crosstalk provides functional plasticity Cancer Research
06/04/2012
Abstract 1242: A broad activity screen in support of a chemogenomic map for kinase signaling research and drug discovery Cancer Research
06/04/2012
Abstract 1238: Gab1 regulates epithelial cell polarity and scattering by acting as a platform for PAR proteins Cancer Research
06/04/2012
Abstract 1236: Ephrin signaling in medulloblastoma Cancer Research
06/04/2012
Abstract 1235: p120ctn is a key effector of Ras-PKCisin-mediated oncogenic signaling Cancer Research
06/04/2012
Abstract 1232: Overcoming resistance to EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 1229: Fibroblast growth factor signaling in ovarian cancer Cancer Research
06/04/2012
Abstract 1227: Modulation of EGF-receptors signaling by small peptidomimetic molecules in breast cancer cells Cancer Research
06/04/2012
Abstract 1225: Integration of HGF/Met signaling and hypoxia response in cancer cell invasion and proliferation Cancer Research
06/04/2012
Abstract 1224: PDGFR as a novel target for the treatment of malignant peripheral nerve sheath tumors Cancer Research
06/04/2012
Abstract 1223: Relief of feedback inhibition of RTK and RAS signaling in V600E BRAF melanomas exposed to RAF inhibitors buffers their effects on signaling Cancer Research
06/04/2012
Abstract 1222: Met-dependent positive and negative signaling cascades in gastric cancer cells Cancer Research
06/04/2012
Abstract 1221: Microscopy based high throughput screen for the mechanistic analyses of ErbB2 degradation in response to Hsp90-targeted therapeutics Cancer Research
06/04/2012
Abstract 1219: Defective catagen entry in EGFR deficient skin precedes cutaneous inflammation Cancer Research
06/04/2012
Abstract 1217: Detection of HER2 expression and phosphorylation in breast cancer CTC samples by CEER™ Cancer Research
06/04/2012
Abstract 1216: c-Met protein expression is regulated by palmitoylation in prostate cancer cells Cancer Research
06/04/2012
Abstract 1214: Effects of dovitinib on fibroblast growth factor receptor-2 (FGFR2) expressing pancreatic cancer Cancer Research
06/04/2012
Abstract 1213: EGFR interacts with fatty acid synthase Cancer Research
06/04/2012
Abstract 1210: Tetraspanin CD63 interacts with extranuclear estrogen receptor alpha and regulates non-genomic signaling pathways in breast cancer Cancer Research
06/04/2012
Abstract 1209: Detection of EGFR T790M mutation in non-small-cell lung cancer patients using colony hybridization assay Cancer Research
06/04/2012
Abstract 1208: Stable EP4 receptor knockdown inhibits prostate cancer growth in vivo Cancer Research
06/04/2012
Abstract 1207: Opposite effects on proliferation and bone metastasis genes by Estrogen Receptor B1 and Estrogen Receptor B2 in the prostate cancer cell line PC3 Cancer Research
06/04/2012
Abstract 1206: Metabotropic glutamate receptor 1 functions as an oncogene in the progression of triple negative breast cancer Cancer Research
06/04/2012
Abstract 1204: MET receptor as a key player responsible for malignant properties and intracellular trafficking and fate of CXCR4 in cervical carcinoma cells Cancer Research
06/04/2012
Abstract 1199: Sorting nexin 2 (SNX2) controls drug sensitivity to molecular targeted anticancer agents through membrane trafficking of c-Met protein in cancer cell Cancer Research
06/04/2012
Abstract 1198: Conversion of triple negative breast cancer cells into HER2 positive cells - a novel therapeutic approach Cancer Research
06/04/2012
Abstract 1197: Soluble uPAR plays a critical role in the progression of meningioma by autocrine signaling Cancer Research
06/04/2012
Abstract 1196: Identification of lung cancer associated oncoantigens as targets for active immunotherapy Cancer Research
06/04/2012
Abstract 1195: Erk activity promotes Notch-dependent HES1 expression in pancreatic cancer cells Cancer Research
06/04/2012
Abstract 1194: p53 negatively regulates the hepatoma growth factor HDGF Cancer Research
06/04/2012
Abstract 1192: ZMIZ1 is elevated in epithelial ovarian cancer due to an upregulated alternative promoter and is associated with p53 mutations Cancer Research
06/04/2012
Abstract 1191: Managing the cross talk: BRCA1 and its regulation of the p53 family, E2f1/Rb and apoptosis Cancer Research
06/04/2012
Abstract 1190: SIRT1 links tumor suppressive NOTCH signaling to p53 Cancer Research
06/04/2012
Abstract 1189: Discovery of RPS25-MDM2/MDMX-p53 regulatory feedback loop Cancer Research
06/04/2012
Abstract 1188: Reprimo, a p53-dependent G2 arrest mediator, reduces tumorigenic capacity in human gastric cancer cell lines Cancer Research
06/04/2012
Abstract 1186: Differences in the levels, localization and DNA binding of p53 in breast cancer cell lines Cancer Research
06/04/2012
Abstract 1185: Plakoglobin ({beta}-catenin) interacts with the transcription factor p53 and regulates the expression of genes involved in tumorigenesis and metastasis Cancer Research
06/04/2012
Abstract 1183: Monoallelic expression in codon 72 of TP53 in heterozygote individuals Cancer Research
06/04/2012
Abstract 1181: P73 regulates the expression of KAI1, metastasis suppressor gene Cancer Research
06/04/2012
Abstract 1179: 15-PGDH inhibits cholangiocarcinogenesis through the induction of TAp63 Cancer Research
06/04/2012
Abstract 1177: The mutational status of the p53 tumor suppressor gene is a determinant of GSTP1 expression and mediates GSTP1-dependent drug resistance in human glioblastoma Cancer Research
06/04/2012
Abstract 1176: Bypassing the dominant-negative effect of mutant p53 in cancer cells Cancer Research
06/04/2012
Abstract 1173: AKT-mTOR pathway mediates mutant p53 gain-of-function by inhibiting autophagy Cancer Research
06/04/2012
Abstract 1169: Non-canonical functions of Mdm2 isoforms in estrogen influenced breast cancer cells with wild-type or mutant p53 Cancer Research
06/04/2012
Abstract 1166: PTEN loss and ERG over-expression as prognostic biomarkers in prostate cancer and identification of downstream biomarkers with potential therapeutic value Cancer Research
06/04/2012
Abstract 1165: Evaluation of HPV infection in penile cancer and its association with p16 and MGMT protein expression levels and pathologic variables Cancer Research
06/04/2012
Abstract 1162: SIX1 protein expression selectively identifies blastemal elements in Wilms tumor Cancer Research
06/04/2012
Abstract 1160: Down-regulation of ATM gene is associated with worse prognosis in sporadic breast carcinomas Cancer Research
06/04/2012
Abstract 1159: Differential expression of BP1 and associated gene networks in breast cancer of African American women and Caucasian American women Cancer Research
06/04/2012
Abstract 1157: Increased expression of RecQ helicases in sporadic primary colorectal cancers Cancer Research
06/04/2012
Abstract 1156: Cell-surface marker discovery for colorectal cancer Cancer Research
06/04/2012
Abstract 1155: A discriminatory set of transcripts, suitable for differentiation of normal, colorectal cancer and adenoma cases from both fresh frozen biopsy and formalin-fixed, paraffin-embedded (FFPE) tissue samples - potential biomarkers of colorectal dyplasia-carcinoma transition Cancer Research
06/04/2012
Abstract 1153: TGF{beta}R1 germline variant Int7G24A but not TGF{beta}R1*6 increases risk for colon cancer Cancer Research
06/04/2012
Abstract 1152: Clinical relevance of elevated microsatellite alterations at selected tetranucleotide repeats in colorectal adenocarcinomas Cancer Research
06/04/2012
Abstract 1150: Genome-wide DNA methylation profiling of cell-free serum DNA in esophageal adenocarcinoma and Barrett's esophagus Cancer Research
06/04/2012
Abstract 1149: The expression of Ki-67, but not IGF1R, predicts a poor disease-free survival in patients with adenocarcinoma of the lung Cancer Research
06/04/2012
Abstract 1148: The relationship between the EMT status in primary lung adenocarcinomas and the DFS, and the results of the molecular analyses of lung adenocarcinoma with regard to the IGF1R and EMT status Cancer Research
06/04/2012
Abstract 1145: Molecular markers of neoadjuvant chemotherapy and combined chemoradiotherapy response in patients with oropharynx squamous cell carcinoma Cancer Research
06/04/2012
Abstract 1143: EZH2 promotes oral squamous cell carcinoma initiation and progression through epigenetic silencing of FHL1 Cancer Research
06/04/2012
Abstract 1142: The expression profile of cancer/testis antigens (CTAs) in head and neck cancer Cancer Research
06/04/2012
Abstract 1141: Telomerase activity in relation to RET mutation status in medullary thyroid carcinoma Cancer Research
06/04/2012
Abstract 1140: Intratumoral mutual exclusivity of dual amplified receptor tyrosine kinase genes in glioblastoma Cancer Research
06/04/2012
Abstract 1531: Reactive astrocytes promote the growth of cancer stem-like cells of metastatic breast tumor by activating Notch signaling in brain Cancer Research
06/04/2012
Abstract 1530: The obligate role of microglia in tumorigenesis in a mouse model of neurofibromatosis-1 optic glioma Cancer Research
06/04/2012
Abstract 1529: Cross-talk between carcinoma-associated fibroblasts and invasive breast cancer cells: Role of RhoA / ROCK signaling Cancer Research
06/04/2012
Abstract 1527: CD44v9 involving in multiple myeloma cells adhesion to bone marrow stromal cell promotes bone erosion by augmenting the activation of HGF-receptor/cMet Cancer Research
06/04/2012
Abstract 1525: Regulation of bone marrow angiogenesis by CXCL12 in the leukemia tumor microenvironment Cancer Research
06/04/2012
Abstract 1524: M402, a novel heparan sulfate mimetic, inhibits pancreatic tumor growth and desmoplasia potentially via sonic hedgehog signaling in an orthotopic mouse model Cancer Research
06/04/2012
Abstract 1523: Trafficking of intracytoplasmic lipid droplets in pancreatic cancer cells by pigment epithelium-derived factor alters triacylglycerol metabolism and cellular invasion Cancer Research
06/04/2012
Abstract 1522: Elevated polyamine levels generate an immunosuppressive oncogenic microenvironment Cancer Research
06/04/2012
Abstract 1521: Expression of the tight junctions protein IGSF5 in the colorectal adenoma-carcinoma sequence Cancer Research
06/04/2012
Abstract 1520: Estrogen modulates angiogenic factors of thyroid tumor microenvironment Cancer Research
06/04/2012
Abstract 1519: Peroxisome proliferator-activated receptor <= promotes colonic inflammation and inflammation-associated tumorigenesis Cancer Research
06/04/2012
Abstract 1518: Multiple myeloma cells cross talk with bone marrow stroma lead to induction of DKK1 expression and produce bortezomib resistance Cancer Research
06/04/2012
Abstract 1517: The outcome of inhibition of stromal TGF{beta}RII in pancreatic cancer is tumor cell-dependent Cancer Research
06/04/2012
Abstract 1516: HB-EGF and PDGF mediate reciprocal interactions of carcinoma cells with cancer-associated fibroblasts to support progression of uterine cervical cancers Cancer Research
06/04/2012
Abstract 1515: The role of the Notch/WISP-1 axis in determining the regulatory effect of mesenchymal stem cells on melanoma cell motility Cancer Research
06/04/2012
Abstract 1513: Functional analysis of TGFBR1 mutations in breast cancer associated fibroblasts Cancer Research
06/04/2012
Abstract 1511: CXCR4 inhibition sensitizes prostate cancer cells to radiotherapy in an in vitro co-culture model Cancer Research
06/04/2012
Abstract 1510: Blockade of the mTOR/NF-{kappa}B signaling axis augments prostate cancer treatment responses through suppression of a microenvironment-derived DNA damage secretory program Cancer Research
06/04/2012
Abstract 1509: Modulation of stromal reaction by PDGF-R tyrosine kinase inhibitor in an orthotopic mice model of gastric carcinoma Cancer Research
06/04/2012
Abstract 1508: TNF-receptor 2 plays a critical role in liver metastasis by regulating sinusoidal endothelial VCAM-1 expression, LY6G+ leukocyte recruitment and transendothelial migration Cancer Research
06/04/2012
Abstract 1507: TGF-beta induced stromal versican promotes cancer invasion in advanced stage serous ovarian cancer Cancer Research
06/04/2012
Abstract 1506: Bone marrow microenvironment mediated redox adaptation confers drug resistance in acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 1505: Stroma-mediated DNA damage resistance of human breast cancer Cancer Research
06/04/2012
Abstract 1504: Dual effect of MMP-9 and its fibronectin-like domain in tumor growth and invasion Cancer Research
06/04/2012
Abstract 1502: Microtubule stabilization alters tumor secretome and fibroblast activation Cancer Research
06/04/2012
Abstract 1500: Bone morphogenetic proteins stimulate mammary fibroblasts to promote mammary tumorigenesis Cancer Research
06/04/2012
Abstract 1499: Periprostatic fat from obese patients promotes prostate cancer growth Cancer Research
06/04/2012
Abstract 1498: Breast adipose mesenchymal stem cells and mammary fibrosis Cancer Research
06/04/2012
Abstract 1496: Changes in white adipose tissue progenitor populations with ovarian cancer Cancer Research
06/04/2012
Abstract 1494: Intrinsic and extrinsic TME factors modulate breast cancer progression Cancer Research
06/04/2012
Abstract 1492: Eavesdropping of crosstalk between adipose stem cells (ASC) and ovarian cancer cells Cancer Research
06/04/2012
Abstract 1489: The role of bone marrow adipocyte-induced HO-1 expression in prostate tumor survival in bone Cancer Research
06/04/2012
Abstract 1487: Tumor-derived microvesicles induce proangiogenic phenotype in endothelial cells via endocytosis Cancer Research
06/04/2012
Abstract 1484: Functional and molecular characterization of macrophage-tumor cell communication Cancer Research
06/04/2012
Abstract 1483: Lung derived fibroblasts influence extracellular matrix composition and dissemination of lung cancers Cancer Research
06/04/2012
Abstract 1482: Abnormal abundance of senescent fibroblasts in the tumor stroma of non-small cell lung cancer patients Cancer Research
06/04/2012
Abstract 1480: Regulation of ovarian tumor growth and stromal cell infiltration by the HU177 biomechanical ECM switch Cancer Research
06/04/2012
Abstract 1479: Targeting breast cancer bone metastases looking at the cross-talk between tumor cells and bone environment Cancer Research
06/04/2012
Abstract 1478: Bone marrow mesenchymal stem cells suppress tumor cell apoptosis and are selectively recruited to early-stage tumors Cancer Research
06/04/2012
Abstract 1477: Tumor metastasis is modulated by tissue stiffness in MMTV-PyMT breast cancer model Cancer Research
06/04/2012
Abstract 1476: Prostate cancer-associated fibroblasts secrete Annexin A1 that facilitates both generation of cancer stem cell-like cells (CSCs) from prostatic malignant epithelial cells and self-renewal/differentiation of CSCs Cancer Research
06/04/2012
Abstract 1475: Localization of mitochondrial targeted GS-nitroxide JP4-039 BODIPY FL conjugate during radioprotection and mitigation in vivo Cancer Research
06/04/2012
Abstract 1474: Hepatocytes either radioprotect or sensitize colorectal cancer cells through nitric oxide-induced oxygen sparing in hypoxic microenvironment Cancer Research
06/04/2012
Abstract 1473: Nanocoated brachytherapy spacers eluting radiosensitizers for biological in situ image-guided radiation therapy of prostate cancer Cancer Research
06/04/2012
Abstract 1472: Comprehensive evaluation of PEGylated gold nanorods for two photon photoluminescence image guided radiation therapy enhancement Cancer Research
06/04/2012
Abstract 1469: Radiosensitization of hepatocellular carcinoma using rationally combined molecular-targeted agents Cancer Research
06/04/2012
Abstract 1467: Inhibition of Cdk4 radiosensitizes breast cancer cells by increasing PP2A levels, and decreasing Bad136 phosphorylation. Cancer Research
06/04/2012
Abstract 1466: Radiosensitization by the mTOR inhibitor RAD001 involves the induction of autophagy in two cancer cell lines Cancer Research
06/04/2012
Abstract 1465: Radiosensitization of NSCLC through modulation of autophagy and senescence Cancer Research
06/04/2012
Abstract 1464: Afatinib, an EGFR/Her-2 dual inhibitor, effectively radiosensitizes bladder cancer cells Cancer Research
06/04/2012
Abstract 1463: PARP inhibition reverses radiation resistance conferred by ETS fusions in prostate cancer Cancer Research
06/04/2012
Abstract 1460: Comparison of radiosensitizing effects of several PARP inhibitors under clinical investigation Cancer Research
06/04/2012
Abstract 1459: Combined inhibition of Wee1 and PARP1 sensitizes pancreatic cancer cells to radiation Cancer Research
06/04/2012
Abstract 1457: Valproic acid enhances radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells Cancer Research
06/04/2012
Abstract 1455: Knock down of the aryl hydrocarbon receptor sensitizes human breast carcinoma cell lines to radio- and chemotherapy Cancer Research
06/04/2012
Abstract 1453: The cannabinoid Win55, 212-2 enhances the response of breast cancer cells to radiation Cancer Research
06/04/2012
Abstract 1448: Whole genome RNAi screen identifies proteasome inhibition as a strategy for NSCLC radiosensitization Cancer Research
06/04/2012
Abstract 1447: Investigating susceptibility to sporadic osteosarcoma by genome-wide copy number analysis Cancer Research
06/04/2012
Abstract 1446: Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem Cancer Research
06/04/2012
Abstract 1445: Integrative genomics identifies actionable targets for therapy in medulloblastoma subgroups Cancer Research
06/04/2012
Abstract 1444: Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma Cancer Research
06/04/2012
Abstract 1442: Side population analysis and gene expression profiling identify Notch pathway genes in neuroblastoma Cancer Research
06/04/2012
Abstract 1440: Validation of potential therapeutic targeting of IL-6/JAK/STAT3 pathway by AZD1480 in neuroblastoma and other pediatric tumors Cancer Research
06/04/2012
Abstract 1439: Loss of expression of SWI/SNF subunits in high risk Wilms tumor is accompanied by global gene expression changes Cancer Research
06/04/2012
Abstract 1435: Phenotype:Genotype correlations of p53 mutation carriers: The 20-year Toronto experience Cancer Research
06/04/2012
Abstract 1434: A mouse model of the most aggressive subgroup of human medulloblastoma Cancer Research
06/04/2012
Abstract 1433: TC21/R-Ras2 is a critical mediator of the Nf1 oncogenic switch Cancer Research
06/04/2012
Abstract 1431: A novel tumor-suppressor role of MyoD, a muscle differentiation factor, in mouse models of medulloblastoma Cancer Research
06/04/2012
Abstract 1430: Characterization of the medulloblastoma splice-ome reveals subgroup-specific changes in alternative splicing and isoform expression patterns Cancer Research
06/04/2012
Abstract 1429: Forkhead box M1 (FoxM1) is a direct transcriptional target of EWS/FLI1 and a regulator of Ewing's sarcoma cell morphology, adhesiveness and tumorigenicity Cancer Research
06/04/2012
Abstract 1427: Signal rewiring induced by EWS/FLI-1 in mouse and human mesenchymal stem cells Cancer Research
06/04/2012
Abstract 1424: KCNJ2 comprises a marker of poor prognosis and a therapeutic target in non-WNT/non-SHH medulloblastoma Cancer Research
06/04/2012
Abstract 1421: Down-regulation of neuronal repressor gene REST inhibits tumor growth in Ewing's sarcoma Cancer Research
06/04/2012
Abstract 1420: Microsomal prostaglandin E2 synthase 1 (mPGES-1) is expressed in neuroblastoma and may represent a novel target for therapy Cancer Research
06/04/2012
Abstract 1418: Dll4-Fc, an inhibitor of Dll4-notch signaling, suppresses liver metastasis of small cell lung cancer cells through down-regulation of NF-kappa-B activity Cancer Research
06/04/2012
Abstract 1417: Role of the matricellular protein SPARC in breast tumor growth and metastatic dissemination Cancer Research
06/04/2012
Abstract 1416: An animal model to study the effects of primary tumor excision on metastatic potential and organ-tropism of residual breast cancer cells Cancer Research
06/04/2012
Abstract 1415: Anti-metastatic properties of tumor-entrained neutrophils Cancer Research
06/04/2012
Abstract 1412: Progesterone and calcitriol attenuate inflammatory cytokines CXCL1 and -2 in endometrial and ovarian cancer cells Cancer Research
06/04/2012
Abstract 1410: TMEM (Tumor MicroEnvironment of Metastasis) in human breast cancer is a blood vessel associated intravasation microenvironment unrelated to lymphatics Cancer Research
06/04/2012
Abstract 1409: Real-time in vivo imaging for sensitive detection of primary and metastatic disease in a human breast-to-lung orthotopic model Cancer Research
06/04/2012
Abstract 1407: Sonic hedgehog signaling and Androgens are linked in tumor-stromal interaction through Epithelial-Mesenchymal transition (EMT) in prostate cancer progression Cancer Research
06/04/2012
Abstract 1406: A new ovarian cancer metastasis model using multicellular spheroids generated from human ovarian cancers tissues Cancer Research
06/04/2012
Abstract 1405: Macrophages induce a transcriptional program that triggers a stable epithelial to mesenchymal transition in prostate cancer cells Cancer Research
06/04/2012
Abstract 1404: Bacterial infection-induced epithelial-to-mesenchymal transition (EMT) of colonic crypt cells with acquired characteristics of stem cells promotes spheroid/organoid formation in vitro and tumorigenesis in vivo Cancer Research
06/04/2012
Abstract 1403: Multiorogan metastasis of human HER-2+ breast cancer in immunodeficient mice Cancer Research
06/04/2012
Abstract 1402: A xenograft pancreatic cancer mouse model to study the function of extracellular DNA in metastasis Cancer Research
06/04/2012
Abstract 1401: Dietary selenium and metastasis in a mouse model Cancer Research
06/04/2012
Abstract 1400: Mouse models for detection of circulating tumor cells from breast cancer Cancer Research
06/04/2012
Abstract 1399: SRC-1 up-regulates CSF-1 expression to potentiate breast cancer metastasis Cancer Research
06/04/2012
Abstract 1398: Using zebrafish xenotransplantation to study the role of Y-Box binding protein (YB-1) in the metastasis of Ewing family tumors Cancer Research
06/04/2012
Abstract 1397: A novel ligand-independent Flt3 allele drives RANKL expression in a murine model of B-precursor acute lymphoblastic leukemia with CNS dissemination Cancer Research
06/04/2012
Abstract 1396: The role of NF{kappa}B/IKK2 pathway in the pathogenesis of lung cancer Cancer Research
06/04/2012
Abstract 1395: Docetaxel pretreatment is associated with increased incidence of CNS-metastases in a murine model of HER2-positive breast cancer Cancer Research
06/04/2012
Abstract 1394: Acute bacterial infection increases lung cancer metastasis via toll-like receptors 2 and 4 Cancer Research
06/04/2012
Abstract 1393: Chitinase-3-like-1 protein overexpression in lung epithelial cells enhances breast cancer metastasis to the lung Cancer Research
06/04/2012
Abstract 1392: Differential effects of Cancer Stem Cells (CSCs) and non-CSCs-targeted therapies on lung primary tumors and metastasis Cancer Research
06/04/2012
Abstract 1389: Arthritis augments breast cancer metastasis: Role of mast cells and SCF/c-Kit signaling Cancer Research
06/04/2012
Abstract 1388: Acquired resistance to anti-VEGF therapy in glioblastoma is associated with an inflammatory and mesenchymal phenotype Cancer Research
06/04/2012
Abstract 1387: The importance of FGF pathway in hepatocellular carcinoma and its role in acquired resistance to anti-angiogenic therapies Cancer Research
06/04/2012
Abstract 1386: Predictive markers of efficacy for an angiopoietin-2 targeting therapeutic in xenograft models Cancer Research
06/04/2012
Abstract 1385: Molecular changes in breast tumors following bevacizumab-based treatment: Final analysis of a randomized neoadjuvant study of bevacizumab or placebo, followed by chemotherapy with or without bevacizumab, in patients with stage II or III breast cancer Cancer Research
06/04/2012
Abstract 1384: Axl and VE-cadherin expression as markers of angiogenesis in human breast cancers Cancer Research
06/04/2012
Abstract 1383: High levels of CD109+ circulating endothelial cells and progenitors as marker of response to bevacizumab and irinotecan in high grade gliomas Cancer Research
06/04/2012
Abstract 1380: Mechanisms of resistance to antiangiogenic therapy in preclinical models of head and neck squamous cell carcinoma (HNSCC) Cancer Research
06/04/2012
Abstract 1379: The role of PERK and the unfolded protein response in the development of resistance to antiangiogenic agents in renal cell carcinoma Cancer Research
06/04/2012
Abstract 1376: TIMP-2 inhibits angiogenesis induced by tumor associated myeloid-suppressor cells Cancer Research
06/04/2012
Abstract 1375: Contrasting effects of VEGF pathway inhibitors in primary and metastatic disease using perioperative neoadjuvant mouse models Cancer Research
06/04/2012
Abstract 1374: Cross-resistance and sensitivity of sunitinib resistant tumor cells Cancer Research
06/04/2012
Abstract 1372: Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer Cancer Research
06/04/2012
Abstract 1370: Tumor endothelial cells acquire drug resistance by MDR1 upregulation via VEGF signaling in tumor microenvironment Cancer Research
06/04/2012
Abstract 1369: Mouse models of clinical oligo- and poly-metastatic progression Cancer Research
06/04/2012
Abstract 1366: Development of murine models of breast cancer metastasis for the evaluation of the efficacy of TGF-{beta} inhibitors as therapeutic agents Cancer Research
06/04/2012
Abstract 1365: The PAMM (pulmonary assessment of metastatic morbidity) diagnostic: A novel non-invasive method for evaluating lung metastasis in murine models Cancer Research
06/04/2012
Abstract 1364: Osteoprotegerin production by breast cancer cells: Regulation by NF-kappaB and role in metastasis Cancer Research
06/04/2012
Abstract 1362: Developing genetically flexible mouse models of sarcoma - a novel functional genomics platform Cancer Research
06/04/2012
Abstract 1361: Sarcoma-relevant genetic events identified in a chimeric mouse model of sarcoma in skeletal muscle Cancer Research
06/04/2012
Abstract 1359: Establishment and characterization of mouse malignant rhabdoid tumor cell lines Cancer Research
06/04/2012
Abstract 1358: Epithelioid and fibroblastic cell elements coexisting within the sarcomatoid renal carcinoma RCC52 cell line ensue divergent routes of tumor differentiation and progression Cancer Research
06/04/2012
Abstract 1357: Creation and establishment of xenograft model for uterine leiomyoma in immunodeficient mice Cancer Research
06/04/2012
Abstract 1356: Vascular endothelial growth inhibitor - potential role in targeted therapy in kidney neoplasma via angiogenic inhibition Cancer Research
06/04/2012
Abstract 1354: Whole transcriptome analysis of primary and metastatic osteosarcoma in the canine model Cancer Research
06/04/2012
Abstract 1353: Inactivation of ribosomal protein L22 promotes transformation by induction of Lin28B Cancer Research
06/04/2012
Abstract 1351: Analysis of the in vivo tumor suppressive potential of PTPROt (truncated protein tyrosine phosphatase receptor-type O) in CLL using a transgenic mouse model Cancer Research
06/04/2012
Abstract 1350: Transgenic expression of PKR induces a myelodysplastic syndrome/pre-leukemia-like condition in mice Cancer Research
06/04/2012
Abstract 1579: Evaluation of Adeno-associated virus like particles (AAVLP) coupled with HER-2 mimotopes as novel carrier system for anti-tumor vaccines Cancer Research
06/04/2012
Abstract 1578: MTBhsp70 fusion protein targeting mesothelin augments tumor specific T cell responses and prolongs survival in a murine model of ovarian cancer Cancer Research
06/04/2012
Abstract 1577: Lactobacilli secreting a tumor antigen and IL15 activates neutrophils and dendritic cells and generates cytotoxic T lymphocytes against cancer cells Cancer Research
06/04/2012
Abstract 1575: A dual immunostimulatory strategy for pancreatic cancer treatment: MUC1 cytoplasmic tail peptide therapeutic vaccine with adjuvant TLR3 agonist poly(I:C12U) Cancer Research
06/04/2012
Abstract 1574: Quantitation of HLA-A2-MAGE3271-279 complexes on the DC surface improves anticancer vaccine designs Cancer Research
06/04/2012
Abstract 1573: MAGED4B drives oral carcinogenesis and is a promising peptide vaccine target for the treatment of oral squamous cell carcinoma Cancer Research
06/04/2012
Abstract 1572: Development of novel and effective therapeutic peptide vaccines against HPV-induced tumors Cancer Research
06/04/2012
Abstract 1571: Developing antigen-specific Th1 epitope based vaccines by excluding immunosuppressive peptide sequences Cancer Research
06/04/2012
Abstract 1570: Frameshift peptides as prophylactic cancer vaccines antigens Cancer Research
06/04/2012
Abstract 1569: Multivalent melanoma vaccine using primary human melanoma cells and a vaccinia virus based antigen retrieval system Cancer Research
06/04/2012
Abstract 1567: mTERT genetic vaccine chemotherapy combination augment antigen-specific immune response and confer tumor protection in time dependent fashion Cancer Research
06/04/2012
Abstract 1565: Mesoporous silicon particle mediated dendritic cell based vaccine formulation showed stronger immunoresponse for the presentation of tumor antigens and adjuvant Cancer Research
06/04/2012
Abstract 1564: Partial immunovesiculectomy by Th-1 dendritic cell vaccination: Implications for immunotherapy of solid tumors Cancer Research
06/04/2012
Abstract 1562: Efficient antigen presentation and induction of anti-tumor immunity by dendritic cells loaded with antigens by electroporation Cancer Research
06/04/2012
Abstract 1558: Innovative biotherapy for brain tumors: Myxoma virus accelerates NK clearance of malignant gliomas Cancer Research
06/04/2012
Abstract 1556: {alpha}-mannosylceramide, a new NKT cell agonist, induces tumor immunity without anergy induction in NKT cells Cancer Research
06/04/2012
Abstract 1555: Epigenetic modulation enhances the therapeutic effect of anti-IL13 receptor {beta}2 antibody in human mesothelioma xenografts Cancer Research
06/04/2012
Abstract 1554: Rosiglitazone and Gemcitabine combination therapy reduces immune suppression and modulates T cell populations in pancreatic cancer Cancer Research
06/04/2012
Abstract 1553: Key determinants of immunotherapy success in frequently-used murine tumor models Cancer Research
06/04/2012
Abstract 1551: Targeting myeloid derived suppressor cells as novel strategy to enhance immunotherapy in murine prostate cancer models Cancer Research
06/04/2012
Abstract 1550: Successful treatment of advanced tumors with chemo-immunotherapy: a combination of cyclophosphamide and inhibition of chemo-resistant immune suppressor cells Cancer Research
06/04/2012
Abstract 1549: Targeting Stat3 induces senescence in breast cancer cells and elicits an immune response inhibiting tumor growth and metastasis Cancer Research
06/04/2012
Abstract 1548: Ultraviolet B-induced platelet-activating factor receptor agonists mediate augmentation of melanoma tumor growth via regulatory T cells: Implication of systemic immunosuppression Cancer Research
06/04/2012
Abstract 1546: Combined direct intratumoral adenoviral delivery and production of Rheoswitch(R)-regulated IL-12 and IFN{alpha} enhances antitumor activity in lung and breast cancer models Cancer Research
06/04/2012
Abstract 1544: Combined oncolytic virotherapy and immunotherapy for malignant mesothelioma Cancer Research
06/04/2012
Abstract 1543: The effect of combination of oncolytic herpes virus hrR3 and Bevacizumab in the treatment of experimental model of human gastric cancer Cancer Research
06/04/2012
Abstract 1541: NK cells are indispensable for suppression of tumor growth and metastasis in transgenic mice overexpressing chemokine CXCL14/BRAK Cancer Research
06/04/2012
Abstract 1540: Inhibition of SDF production by brain tumor cells reduces brain tumor bed effect Cancer Research
06/04/2012
Abstract 1539: Antibody targeted CpG for the immunotherapy of solid tumors Cancer Research
06/04/2012
Abstract 1538: Enhanced antitumor effects of intratumoral (IT) hu14.18-IL2 immunocytokine (IC) compared to intravenous (IV) hu14.18-IL2 are distinguished by increased activated tumor infiltrating lymphocytes (TILs) and IC retention Cancer Research
06/04/2012
Abstract 1537: Combined Tbet and IL-12 gene therapy elicits and recruits superior anti-tumor immunity in vivo Cancer Research
06/04/2012
Abstract 1536: A novel immunocytokine generates a CD8+ T cell-mediated anti-tumor response in vivo Cancer Research
06/04/2012
Abstract 1535: Intratumoral chitosan/interleukin-12 immunotherapy reduces breast cancer metastasis Cancer Research
06/04/2012
Abstract 1534: Hes1 regulates hypoxia induced chemoresistance of myeloma cells Cancer Research
06/04/2012
Abstract 1533: Fibrocytes promote metastasis by recruiting Ly-6C+ myeloid cells Cancer Research
06/04/2012
Abstract 1532: The identification of osteoblastic and osteolytic factors in prostate cancer bone metastases Cancer Research
06/04/2012
Abstract 1125: Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer Cancer Research
06/04/2012
Abstract 1123: AML cells have low reserve capacity in their respiratory chain complexes leading to increased sensitivity to palmitate-induced cell death Cancer Research
06/04/2012
Abstract 1122: Lipoic acid analogs induce ROS, leading to potent mitochondrial enzyme inhibition, metabolic dysfunction and cell death in tumor cells Cancer Research
06/04/2012
Abstract 1121: ER-negative breast cancer survive mitochondrial IMS-stress via SIRT3 activation Cancer Research
06/04/2012
Abstract 1120: {alpha}-Tocopherol protects cells from lipid peroxidation and rescues tumorigenic phenotypes in CS/CSL patients with germline SDHx variants Cancer Research
06/04/2012
Abstract 1118: Protease-integrin regulates mitochondrial biogenesis in glioma xenograft cells Cancer Research
06/04/2012
Abstract 1117: Investigating the role of PTEN-induced kinase 1 in cancer development and pathogenesis Cancer Research
06/04/2012
Abstract 1115: p32 is a downstream effector of c-Myc induced glutamine addiction Cancer Research
06/04/2012
Abstract 1114: Loss of OPA1 expression results in apoptosis for cells overexpressing c-Myc Cancer Research
06/04/2012
Abstract 1113: Role of the microRNA-23~27~24 clusters in osteosarcoma Cancer Research
06/04/2012
Abstract 1112: Identification of microRNA-based therapeutic candidates using a unique lentiviral microRNA overexpression library Cancer Research
06/04/2012
Abstract 1111: Synthetic microRNA (miR)-181a nanoparticles (NP) target RAS and sensitize cells to daunorubicin (DNR) in acute myeloid leukemia (AML) Cancer Research
06/04/2012
Abstract 1110: Effect of miR-29 on cisplatin sensitivity of ovarian cancer cells Cancer Research
06/04/2012
Abstract 1109: Pleiotropic actions of miR-153 support colorectal cancer progression through enhanced invasion and platinum based chemotherapy resistance Cancer Research
06/04/2012
Abstract 1107: MicroRNA-182 acts as a chemosensitizer in GBM by repressing Bcl2L12 Cancer Research
06/04/2012
Abstract 1106: Targeting both non-coding and coding sequences with small RNA efficiently knocks down DNA repair genes and radiosensitizes human tumor cells Cancer Research
06/04/2012
Abstract 1105: MicroRNAs and their targets genes promote cisplatin resistance in epithelial ovarian cancer cells Cancer Research
06/04/2012
Abstract 1104: Nuclear translocalization of DICER correlates with high-risk clinical/histologic features in melanoma Cancer Research
06/04/2012
Abstract 1101: Modulation of expression of specific oncogenic and tumor suppressor microRNAs enhanced therapeutic efficacy of 4-HPR and EGCG in human malignant neuroblastoma cells Cancer Research
06/04/2012
Abstract 1097: MicroRNA expression in white blood cells of CML patients: Differential expression in responders and non-responders to imatinib Cancer Research
06/04/2012
Abstract 1096: Loss of miR-200 family of microRNAs confers resistance to tamoxifen in human breast cancer cells Cancer Research
06/04/2012
Abstract 1095: Comprehensive miRNA profiling of taxane-resistant human breast and ovarian cancer cell lines using the SmartChip real-time PCR system Cancer Research
06/04/2012
Abstract 1094: MicroRNA-30a inhibits vimentin expression and as a prognostic marker in breast cancer Cancer Research
06/04/2012
Abstract 1093: Resveratrol inhibits prostate cancer metastasis by targeting microRNA-21 Cancer Research
06/04/2012
Abstract 1091: Cannabinoids inhibit epidermal growth factor receptor transactivation in lung cancer cells Cancer Research
06/04/2012
Abstract 1090: Impact of CXCL1/CXCR2 signaling in ovarian cancer proliferation Cancer Research
06/04/2012
Abstract 1089: Effect of lenvatinib (E7080) on site specific phosphorylation in cancer cells with activated FGFR2 signaling Cancer Research
06/04/2012
Abstract 1088: {gamma}-Tocotrienol inhibits HGF-dependent mitogenesis and Met activation in highly malignant mammary tumor cells Cancer Research
06/04/2012
Abstract 1087: TGF-{beta} activated EGFr as a bypass mechanism for the acquired resistance of MET inhibitors in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 1086: Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression Cancer Research
06/04/2012
Abstract 1083: Nuclear receptors as novel targets in ER negative breast cancer Cancer Research
06/04/2012
Abstract 1082: Stochastic control of abnormal morphogenesis induced by the ErbB2 oncoprotein Cancer Research
06/04/2012
Abstract 1080: Effect of IGF2 overexpression on the tumorigenicity of human ovarian carcinoma cells Cancer Research
06/04/2012
Abstract 1078: ErbB/Pi3K signaling contributes to EGFR ligand expression in colorectal cancer cells Cancer Research
06/04/2012
Abstract 1075: Bone morphogenetic protein type I receptor antagonists decrease growth and induce cell death of lung cancer cell lines Cancer Research
06/04/2012
Abstract 1074: Keratinocyte growth factor suppresses malignant phenotype of cutaneous squamous carcinoma cells Cancer Research
06/04/2012
Abstract 1073: Cell surface F1-ATPase, a new potential target in colorectal cancer Cancer Research
06/04/2012
Abstract 1071: Epidermal growth factor induces anterograde lysosome trafficking via activation of p38 Cancer Research
06/04/2012
Abstract 1070: Differential response dynamic of leukemia cells to GM-CSF and IL-3 stimulation in signal transduction pathways Cancer Research
06/04/2012
Abstract 1068: Inhibition of the phosphorylation of eIF4 molecules sensitizes EGFR expressing breast cancers to EGFR inhibitors Cancer Research
06/04/2012
Abstract 1066: Combination synergy of JAK inhibitor, BVB808, and FGFR inhibitor, BGJ398, in an FGFR3-driven multiple myeloma model Cancer Research
06/04/2012
Abstract 1065: Growth factor-mediated resistance to BRAF/MEK inhibitors in BRAF mutant melanoma Cancer Research
06/04/2012
Abstract 1064: Sloan-Kettering Institute (Ski) protein plays distant roles in activation of Smad proteins in response to nodal and TGF-{beta} in prostate cancer cells Cancer Research
06/04/2012
Abstract 1061: EZH2 expression in different subtypes of human breast cancer Cancer Research
06/04/2012
Abstract 1060: Structural insights into the regulation and the recognition of histone marks by the SET domain of histone lysine HMTase NSD1, NSD2/MMSET/WHSC1, and NSD3/WHSC1L1 Cancer Research
06/04/2012
Abstract 1059: SUV39H1 promotes HCC tumorigenesis and is targeted by tumor suppressive miRNA-125b Cancer Research
06/04/2012
Abstract 1058: Mutations in isocitrate dehydrogenase 1 and 2 are associated with DNA hypermethylation in intrahepatic cholangiocarcinomas Cancer Research
06/04/2012
Abstract 1057: Mutation of EZH2 A677 in human B-cell lymphoma promotes hyper-trimethylation of H3K27 Cancer Research
06/04/2012
Abstract 1056: Deregulated HDAC9 expression in breast cancer is associated with basal molecular subtype Cancer Research
06/04/2012
Abstract 1055: Enhancer of Zeste Homologue 2 (EZH2) may relate to progression of intra and extrahepatic cholangiocarcinoma Cancer Research
06/04/2012
Abstract 1050: Extended treatment with azacitidine maintains low DNMT1 levels and DNA methylation in MDA-MB-231 cells in vitro and in vivo Cancer Research
06/04/2012
Abstract 1049: DNMT3b increases transformation efficiency and accelerates carcinogen induced transformation of human bronchial epithelial cells Cancer Research
06/04/2012
Abstract 1047: Suppression of the chromatin remodeling protein CHD3 and platinum resistance in ovarian cancer Cancer Research
06/04/2012
Abstract 1046: The histone methyl transferase MMSET/WHSC1 promotes an epithelial-mesenchymal transition and invasive properties of prostate cancer Cancer Research
06/04/2012
Abstract 1044: Breast cancer subtype-specific regulation of gene transcription and therapeutic response by functional crosstalk between LSD1 and HDACs Cancer Research
06/04/2012
Abstract 1043: Combined targeting of chromatin modifying enzymes LSD1, histone deacetylases (HDACs) and EZH2 has superior efficacy against human acute myeloid leukemia cells. Cancer Research
06/04/2012
Abstract 1042: Down-regulation of UTX contributes to lung cancer progression Cancer Research
06/04/2012
Abstract 1040: A truncated DNMT3B protein (DNMT3B7) drives DNA methylation and suppresses growth in human neuroblastoma Cancer Research
06/04/2012
Abstract 1039: Histone deacetylase 8 (HDAC8) target identification and mechanism of action of HDAC8 isoform-specific inhibitors Cancer Research
06/04/2012
Abstract 1038: Plasma S-adenosylmethionine levels, genetic polymorphisms of DNMT1 and DNMT3A, and LINE-1 DNA methylation among Chinese in Singapore Cancer Research
06/04/2012
Abstract 1037: Histone lysine methyltransferase EHMT2 is involved in proliferation, apoptosis, and DNA methylation of human neuroblastoma cells Cancer Research
06/04/2012
Abstract 1036: Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation Cancer Research
06/04/2012
Abstract 1035: SETD2, a histone methyltransferase, is misregulated in advanced clear cell renal cell carcinoma (ccRCC) Cancer Research
06/04/2012
Abstract 1033: Transcriptional factor ZBP-89 interacts with DNMT1 and HDAC3 to regulate Bak expression Cancer Research
06/04/2012
Abstract 1032: Post-menopausal women with luminal A subtype might not require breast radiotherapy: Preliminary results from a randomized clinical trial of tamoxifen + radiation Cancer Research
06/04/2012
Abstract 1031: Estrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy Cancer Research
06/04/2012
Abstract 1030: Pathology, BRCA status, and ancestry among Hispanics with breast cancer Cancer Research
06/04/2012
Abstract 1029: The association of body mass index with risk of endometrial cancer subtypes: Pooled analysis in E2C2 Cancer Research
06/04/2012
Abstract 1025: Risk of diffuse large B-cell lymphoma in solid organ transplant recipients Cancer Research
06/04/2012
Abstract 1023: Comparison of the effects of aflibercept (VEGF Trap) and small molecule kinase inhibitors on tumors and normal organs in mouse models Cancer Research
06/04/2012
Abstract 1022: Notch regulates the egression of angio-supportive bone marrow-derived cells after chemotherapy Cancer Research
06/04/2012
Abstract 1020: Recruitment of Tie2-expressing monocytes is associated with the heightened invasive phenotype of gliomas after antiangiogenic therapies Cancer Research
06/04/2012
Abstract 1019: CD34+ progenitors resident in the human white adipose tissue promote tumor angiogenesis, growth and metastases in orthotopic models of breast cancer Cancer Research
06/04/2012
Abstract 1017: Protooncogenic TLR4 generates NANOG-dependent tumor-initiating stem-like cells through LIN28-Let7 pathway in experimental and clinical carcinogenesis Cancer Research
06/04/2012
Abstract 1016: Asymmetry-defective oligodendrocyte progenitors are glioma precursors Cancer Research
06/04/2012
Abstract 1015: Mammary stem cells increase late in embryogenesis, facilitating their characterization and revealing links to breast cancer Cancer Research
06/04/2012
Abstract 1014: Targeting cancer stem cells by a Notch2/Notch3 cross-reactive antibody inhibits tumor growth and delays tumor recurrence in pancreatic cancer Cancer Research
06/04/2012
Abstract 1012: MicroRNA-203 restricts the proliferation capacity of normal colon and colon cancer stem cells by regulating the expression of Tcf4 Cancer Research
06/04/2012
Abstract 1011: NOTCH1 signaling is essential for leukemia initiating cell self-renewal in T-ALL Cancer Research
06/04/2012
Abstract 1010: Effect of dietary energy balance modulation on the ability of metformin to inhibit skin tumor promotion Cancer Research
06/04/2012
Abstract 1009: Regression of rectal polyps in familial adenomatous polyposis patients by freeze-dried black raspberries is associated with the demethylation and reactivation of tumor suppressor genes Cancer Research
06/04/2012
Abstract 1006: Soluble epoxide hydrolase gene deficiency attenuates colitis-induced carcinogenesis in IL-10 knockout mice Cancer Research
06/04/2012
Abstract 1005: Targeting COX-LOX and EGFR pathways simultaneously by licofelone and gefitinib lead to complete blockade of progression of PanINs to pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 1004: Impact of genetic polymorphisms on colorectal adenoma recurrence and toxicity in a COX-2 inhibitor trial (Celecoxib): Results from a pilot study Cancer Research
06/04/2012
Abstract 1002: Induced dependency on amino acid metabolism in proliferating cancer cells upon PKM2 activation Cancer Research
06/04/2012
Abstract 1001: Reductive tricarboxylic acid metabolism of glutamine mediates lipogenesis under hypoxia Cancer Research
06/04/2012
Abstract 1000: Oncogenic Kras inhibits mitochondrial metabolism by regulating the pyruvate dehydrogenase complex under conditions of nutrient stress Cancer Research
06/04/2012
Abstract 999: Potential role of reactive oxygen species in mediating glioblastoma stem cell differentiation Cancer Research
06/04/2012
Abstract 998: Oncogenic potential of mitochondria regulate the cellular tumor characteristics Cancer Research
06/04/2012
Abstract 997: Oncogenic tyrosine kinases are localized to mitochondria and regulate cancer metabolism by phosphorylating key components of pyruvate dehydrogenase kinase complex Cancer Research
06/04/2012
Abstract 996: MBD-capture coupled with next generation sequencing elucidates genome-wide crosstalk between epigenetic marks and its role in cancer Cancer Research
06/04/2012
Abstract 2724: Activity of the specific anti-ADAM17 inhibitory IgG antibody (Ab), D1(A12) in an ovarian cancer model in vivo Cancer Research
06/04/2012
Abstract 2723: Sarilumab (REGN88), a fully-human anti-IL6R antibody, inhibits tumor growth in preclinical models, as a single agent and in combination with the VEGF blocker aflibercept Cancer Research
06/04/2012
Abstract 2722: Active recruitment of immune effector cells mediates in vivo tumor growth inhibition by enavatuzumab, an antibody to human TWEAK receptor Cancer Research
06/04/2012
Abstract 2720: Sym004, a novel anti-EGFR antibody mixture augments radiation response in human lung and head and neck cancer models Cancer Research
06/04/2012
Abstract 2718: REGN1400, a fully-human ERBB3 antibody, potently inhibits tumor growth in preclinical models, both as a monotherapy and in combination with EGFR or HER2 blockers Cancer Research
06/04/2012
Abstract 2717: Reolysin: A novel reovirus-based agent that induces endoplasmic reticular stress in RAS-activated pancreatic cancer Cancer Research
06/04/2012
Abstract 2716: Development of tanapox virus for oncolytic therapy Cancer Research
06/04/2012
Abstract 2715: Treatment of disseminated HER-2 carcinomas with a HER-2-retargeted oncolytic herpes virus Cancer Research
06/04/2012
Abstract 2714: Vesicular stomatitis virus as an oncolytic agent against pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 2713: Adenovirus E1A binding to p300 is essential for synergistic cell killing in combination with chemotherapeutic drugs in prostate cancer cells Cancer Research
06/04/2012
Abstract 2712: A non-replicating adenovirus expressing Hey1 is cytotoxic to prostate cancer cells Cancer Research
06/04/2012
Abstract 2707: Long-term significance (15 years) of pathological complete response after dose-dense neo-adjuvant chemotherapy in breast cancer Cancer Research
06/04/2012
Abstract 2706: Phase 2 study with pharmacokinetics (PK) analysis of sorafenib and vinorelbine in metastatic breast cancer Cancer Research
06/04/2012
Abstract 2705: In search of a cost effective sentinel node biopsy technique: A randomized trial comparing the use of methylene blue and patent blue violet to identify sentinel node in breast cancer Cancer Research
06/04/2012
Abstract 2704: Tetraspanin CD151 drives mammary tumor onset and metastasis by coordinating integrin-dependent cell adhesion, motility, survival and signaling Cancer Research
06/04/2012
Abstract 2703: Final results of a phase 2 trial using a novel, non-anthracycline neoadjuvant chemotherapy regimen in Her2-positive breast cancer Cancer Research
06/04/2012
Abstract 2702: Effects of Src and IGF1R inhibition on acquired endocrine therapy resistant breast cancer Cancer Research
06/04/2012
Abstract 2701: ROR{alpha} suppresses breast tumor progression by inducing cell polarization and inhibiting cell invasion Cancer Research
06/04/2012
Abstract 2700: The use of a novel receptor targeted (CD206) Tc99m-labeled intraoperative node mapping agent for preoperative SPECT/CT in imaging head/neck cancer, breast cancer and melanoma Phase 3 trials: Localization and concordance in lymph nodes Cancer Research
06/04/2012
Abstract 2699: Phase II study evaluating the effect of tetrathiomolybdate on circulating endothelial progenitor cells in patients with high risk for breast cancer recurrence Cancer Research
06/04/2012
Abstract 2698: Improved therapeutic activity of Isoflavone-G2535 and Docetaxel combination in hormone refractory prostate cancer Cancer Research
06/04/2012
Abstract 2697: Role of a novel flavonoid enriched in ocimum sanctum linn for prostate cancer chemoprevention and therapy Cancer Research
06/04/2012
Abstract 2696: Modulation of intracrine androgen signaling in bone metastatic castrate resistant prostate cancer (bmCRPC) by MDV3100 Cancer Research
06/04/2012
Abstract 2695: Olfactomedin 4 gene is associated with progression of prostate cancer: Evidence from an OLFM4 knockout mouse model Cancer Research
06/04/2012
Abstract 2693: Pharmacogenetic determinants associated with sunitinib-induced toxicity and ethnic difference in Korean patients with metastatic renal cell carcinoma Cancer Research
06/04/2012
Abstract 2691: A randomized Phase III study comparing the efficacy of Bacillus Calmette Guerin strain Tice versus Connaught for immunotherapy of non-muscle invasive bladder cancer Cancer Research
06/04/2012
Abstract 2690: Evaluation of the hemostatic status in patients with prostate cancer using thromboelastography and tissue factor- microparticles Cancer Research
06/04/2012
Abstract 2689: Inhibition of metastasis of circulating tumor cells by extracellular matrix secreted by human embryonic cells Cancer Research
06/04/2012
Abstract 2688: Color-coded imaging of the pre-metastatic niche in the lung and liver indicates the involvement of cancer-associated fibroblasts Cancer Research
06/04/2012
Abstract 2687: Imaging sub-cellular dynamics of proliferating intra- and extra-vascular cancer cells Cancer Research
06/04/2012
Abstract 2685: Imaging the various mechanisms of cancer-cell killing by Salmonella typhimurium A1-R Cancer Research
06/04/2012
Abstract 2684: Imaging lung colony formation by osteosarcoma cells expressing {alpha}v integrin-GFP in nude mice Cancer Research
06/04/2012
Abstract 2683: Cellmap: Tumor cell subpopulation analysis in immunohistochemistry stained tumor tissue Cancer Research
06/04/2012
Abstract 2682: New diagnostic and therapeutic target KU-MEL9 for chronic myeloid leukemia (CML) Cancer Research
06/04/2012
Abstract 2681: Multicolor imageable orthotopic tumorgraft models of human patient pancreatic cancer Cancer Research
06/04/2012
Abstract 2680: Characterization of cultured circulating melanoma cells for individualized therapy Cancer Research
06/04/2012
Abstract 2679: Color-coded selective chemotherapy of methioninase-synchronized S-phase cancer cells expressing cell-cycle-specific fluorescent reporters: A general approach to the treatment of cancer Cancer Research
06/04/2012
Abstract 2678: Traditional Chinese Medicine (TCM) in combination with S. typhimurium A1-R for cancer treatment Cancer Research
06/04/2012
Abstract 2677: Determination of the optimal route of administration of Salmonella typhimurium A1-R to target breast cancer in nude mice Cancer Research
06/04/2012
Abstract 2676: A secreted tissue engineered extracellular matrix (shECM) prevents recurrence in post-resection pancreatic cancer models Cancer Research
06/04/2012
Abstract 2675: CXCL12 (SDF-1) and its truncation products in patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) receiving ON 01910.Na (Rigosertib) in phase I trials Cancer Research
06/04/2012
Abstract 2673: Relationship between serum hormone levels and pharmacokinetics (PK) of PEGylated liposomal doxorubicin (PLD) in patients with refractory ovarian cancer Cancer Research
06/04/2012
Abstract 2672: Phase 1 pharmacokinetics (PK) & pharmacodynamics (PD) of PEGylated hyaluronidase PH20 (PEGPH20) in patients with solid tumors Cancer Research
06/04/2012
Abstract 2671: CYP2D6 polymorphisms are not associated with tamoxifen outcome in premenopausal women with ER positive breast cancer of the POSH cohort Cancer Research
06/04/2012
Abstract 2670: Genetic variants in human epidermal growth factor receptor (HER) family gene predict tumor recurrence in breast cancer Cancer Research
06/04/2012
Abstract 2669: Early-phase trials in patients with advanced gallbladder cancer and cholangiocarcinoma: The MD Anderson Clinical Center for Targeted Therapy experience Cancer Research
06/04/2012
Abstract 2668: The impact of CYP2C19 polymorphisms on plasma concentrations and metabolic ratios of tamoxifen and its metabolites in Asian breast cancer patients Cancer Research
06/04/2012
Abstract 2667: Molecular profiling guided human PDX tumor model selection for preclinical drug evaluation Cancer Research
06/04/2012
Abstract 2666: Receptor protein tyrosine phosphatase type kappa is a prognostic marker, essential for regulating malignant behavior of glioma cells Cancer Research
06/04/2012
Abstract 2665: Oxaliplatin as an alternative for the treatment of high grade prostate cancers. Identification of serine hydroxymethyl transferases (SHMT) as selective biomarkers of oxaliplatin sensitivity via the modulation of DNA methylation. Cancer Research
06/04/2012
Abstract 2664: Biological relevance of CYP2D6 phenotype and low dose tamoxifen activity within a randomized phase II pre-surgical trial. Cancer Research
06/04/2012
Abstract 2663: Phase I study of azacitidine and cisplatin in patients with advanced head and neck or non-small cell lung cancer Cancer Research
06/04/2012
Abstract 2662: Racial disparities in the surgical outcomes after esophagectomy for esophageal cancer Cancer Research
06/04/2012
Abstract 2661: Healthcare utilization by race and sex among a nationally representative sample of adults with and without a personal history of cancer Cancer Research
06/04/2012
Abstract 2660: Prevalence of obesity among subjects with a personal history of cancer: A call for action among cancer survivors and care providers Cancer Research
06/04/2012
Abstract 2659: Cilastatin attenuates cisplatin-induced proximal tubular cell damage without compromising antitumoral activity Cancer Research
06/04/2012
Abstract 2658: Chemotherapy within last 30 days of life: differences between hematologic malignancy (HM) and solid tumor (ST) patients at a cancer hospital Cancer Research
06/04/2012
Abstract 2657: Younger age correlates with depression but not adaptive maturity in adult cancer patients Cancer Research
06/04/2012
Abstract 2656: Predictors of bloodstream infection associated with permanently implantable venous port in solid cancer patients Cancer Research
06/04/2012
Abstract 2655: Esophagectomy with extended 2-field lymph node dissection for patients with thoracic esophageal carcinoma Cancer Research
06/04/2012
Abstract 2653: Racial and ethnic differences in survival after cancer diagnosis Cancer Research
06/04/2012
Abstract 2652: Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib +/- megestrol acetate for patients with cancer-related anorexia/cachexia syndrome Cancer Research
06/04/2012
Abstract 2650: A combined bioinformatics and GWAS approach identifies a functional 3'UTR insertion/deletion in YES1 associated with bladder cancer risk Cancer Research
06/04/2012
Abstract 2649: Maternal and offspring folate metabolic genes and the risk of childhood acute lymphoblastic leukemia (ALL) Cancer Research
06/04/2012
Abstract 2648: Gene-asbestos interaction and lung cancer risk from a genome-wide association study Cancer Research
06/04/2012
Abstract 2647: Influence of quercetin-rich foods intake on microRNA expression in EAGLE lung cancer tissues Cancer Research
06/04/2012
Abstract 2646: Genetic determinants of PAH-DNA adduct level and nucleotide excision repair among non-smokers in a high risk area for esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2645: Genomic deletions and point mutations in the STK11 gene in Peutz-Jeghers Chilean families Cancer Research
06/04/2012
Abstract 2644: No evidence for increased risk of cancers other than testicular cancer among first-degree relatives of testicular germ cell tumor (TGCT) patients from multiple-case TGCT families Cancer Research
06/04/2012
Abstract 2642: Dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas Cancer Research
06/04/2012
Abstract 2641: Polymorphisms in pattern recognition genes in the innate immunity system and risk of non-Hodgkin lymphoma Cancer Research
06/04/2012
Abstract 2640: Risk of cytochrome P450 1B1 missense polymorphisms in renal cell carcinoma Cancer Research
06/04/2012
Abstract 2639: A community-based study of nucleotide excision repair polymorphisms in relation to risk of non-melanoma skin cancer Cancer Research
06/04/2012
Abstract 2638: Genetic association analysis of the AMP dependent protein kinase complex and NHL risk Cancer Research
06/04/2012
Abstract 2637: Application of identity-by-descent (IBD) approach to genetic mapping of susceptibility locus in hereditary esophageal squamous cell carcinoma (ESCC) by high density SNP array analysis Cancer Research
06/04/2012
Abstract 2636: Nonmelanoma skin cancer as a marker of a cancer-prone phenotype: Potential role of DNA repair gene variants Cancer Research
06/04/2012
Abstract 2635: association between CASP7 and CASP14 genetic polymorphisms and the risk of childhood leukemia Cancer Research
06/04/2012
Abstract 2634: Polymorphisms in DNA repair genes and risk of multiple myeloma Cancer Research
06/04/2012
Abstract 2633: Single nucleotide polymorphisms in one carbon metabolism genes are associated with methylation patterns and plasma metabolites in high risk smokers based on gender Cancer Research
06/04/2012
Abstract 2632: Genetic variants of iron-dependent metabolism genes and risk of upper gastrointestinal cancers Cancer Research
06/04/2012
Abstract 2631: Analysis of PI3K pathway genes in bladder cancer Cancer Research
06/04/2012
Abstract 2630: DNA repair single nucleotide polymorphisms interact with indoor tanning and melanoma Cancer Research
06/04/2012
Abstract 2629: Common genetic variants in the vitamin D pathway including genome-wide associated variants in relation to glioma risk and outcome Cancer Research
06/04/2012
Abstract 2628: Genome-wide sequencing identifies ATM as a pancreatic cancer susceptibility gene Cancer Research
06/04/2012
Abstract 2627: Polymorphisms of retinol transporter genes and risk of head and neck cancer Cancer Research
06/04/2012
Abstract 2626: Apoptosis-related single nucleotide polymorphisms and the risk of non-small cell lung cancer in a case-control study of women Cancer Research
06/04/2012
Abstract 2625: Is familial risk of cancer limited to relatively early onset cases Cancer Research
06/04/2012
Abstract 2624: Evaluation of the association of the ABO blood group SNP rs505922 with breast cancer phenotypes Cancer Research
06/04/2012
Abstract 2623: The role of polymorphisms in DNA repair genes and HPV 16 integration status in cervical dysplasia Cancer Research
06/04/2012
Abstract 2622: SNP markers in the FGF9 and MAP3K1 region associate with testicular germ cell tumor susceptibility Cancer Research
06/04/2012
Abstract 2621: Relative excess risk due to interactions between GWAS-identified susceptibility loci and other breast cancer risk factors Cancer Research
06/04/2012
Abstract 1139: Novel, cellular active inhibitors of G6PD, a key mediator of ROS-induced cellular stress Cancer Research
06/04/2012
Abstract 1138: The emerging role of thioredoxin-1 on ROS and metabolic reprogramming in cisplatin resistant lung cancer Cancer Research
06/04/2012
Abstract 1137: Imp2 controls oxidative phosphorylation in glioblastoma cancer stem cells Cancer Research
06/04/2012
Abstract 1135: Bioluminescent methods to investigate cellular metabolic status: NAD(P)/NAD(P)H levels, redox potential, and hydrogen peroxide concentration Cancer Research
06/04/2012
Abstract 1134: Fumarate activates NRF2 in tissues with fumarate hydratase mutation Cancer Research
06/04/2012
Abstract 1133: Glucose deprivation-induced intracellular reactive oxygen species activates the PI3K-AKT axis Cancer Research
06/04/2012
Abstract 1132: Regulation of the glutamine-to-lipid pathway by HIF: Reductive TCA cycle is a metabolic signature of VHL deficiency Cancer Research
06/04/2012
Abstract 1129: Mitochondrial dysfunction precedes tumor progression in ulcerative colitis, but it is restored in advanced dysplasia and cancer Cancer Research
06/04/2012
Abstract 1128: The role of peptide deformylase in the apoptosis of c-Myc overexpressing cancers Cancer Research
06/04/2012
Abstract 1126: Mitochondrial DNA copy number and colorectal cancer risk: Results from the Shanghai Women's Health Study Cancer Research