Medical Research Articles Published in June 2012

With a Free Docphin Account, you create a custom list of medical research journal sources that are easy to navigate, search our extensive databse of articles, save and organize your articles into folders, set up alerts to be notificed of research articles that match your interests ... and much more.

Login or Register
06/04/2012
Abstract 2620: Contribution of risk variant in miR-125b binding site of BMPR1B in women of African ancestry with breast cancer Cancer Research
06/04/2012
Abstract 2619: Relevance of mismatch repair deficiency in ovarian cancer Cancer Research
06/04/2012
Abstract 2618: Chemokine-associated loci and prostate cancer among men of African descent Cancer Research
06/04/2012
Abstract 2617: Cytokine and cytokine receptors of adaptive immune response are differentially associated with breast cancer risk in women of African ancestry and European ancestry Cancer Research
06/04/2012
Abstract 2616: Association of UGT2B17 gene copy number variation with breast cancer risk: The Nashville Breast Health Study Cancer Research
06/04/2012
Abstract 2615: Genetic variations in angiogenesis-related genes in prostate cancer recurrence Cancer Research
06/04/2012
Abstract 2614: Distinguished features of ERG oncoprotein expression among matched cohorts of African-American and Caucasian-American prostate cancer patients Cancer Research
06/04/2012
Abstract 2613: Racial/Ethnic specific polygenic models of breast cancer risk Cancer Research
06/04/2012
Abstract 2612: The PROFILE study; Germline genetic profiling: Correlation with targeted prostate cancer screening and treatment Cancer Research
06/04/2012
Abstract 2611: Role of circadian genes in breast cancer: Analysis of the CECILE study, a population-based case-control study conducted in France Cancer Research
06/04/2012
Abstract 2609: Addition of ER and PTEN, but not cytokeratins, aids identification for BRCA1 carriers in Malaysian breast cancer patients Cancer Research
06/04/2012
Abstract 2608: Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer Cancer Research
06/04/2012
Abstract 2607: Genetic variants in the vitamin D pathway and breast cancer disease free survival Cancer Research
06/04/2012
Abstract 2606: Absence of association between common genetic polymorphisms in the TERT-CLPTM1L locus and breast cancer risk in women of African descent Cancer Research
06/04/2012
Abstract 2605: Apolipoprotein E polymorphisms, plasma cholesterol, and prostate cancer Cancer Research
06/04/2012
Abstract 2604: Transforming growth factor beta signaling pathway variants and breast cancer risk: results from the Shanghai Breast Cancer Genetics Study Cancer Research
06/04/2012
Abstract 2603: Subtype-specific ovarian cancer risk associated with SNPs in IL1A Cancer Research
06/04/2012
Abstract 2602: CHEK2 contribution to hereditary breast cancer in non-BRCA famillies Cancer Research
06/04/2012
Abstract 2601: Polymorphisms in oxidative stress genes, physical activity and breast cancer risk Cancer Research
06/04/2012
Abstract 2599: IGF gene pathway and progression to fatal prostate cancer after diagnosis in men of European ancestry Cancer Research
06/04/2012
Abstract 2598: An association study between AGTR2 and MAS1 gene polymorphisms with breast cancer among Brazilian women Cancer Research
06/04/2012
Abstract 2597: Identification of new genes for hereditary breast cancer Cancer Research
06/04/2012
Abstract 2596: Correlation of TGF beta receptor II and pSmad2 expression with clinico-pathological factors in human breast cancer: An immunohistochemical observation from the Shanghai Breast Cancer Study Cancer Research
06/04/2012
Abstract 2595: Screening for genomic rearrangements in BRCA1 and BRCA2 genes in Algerian breast/ovarian cancer families Cancer Research
06/04/2012
Abstract 2594: Chamomile (Matricaria chamomilla L.) upregulates heme oxygenase-1 through activation of ERK-Nrf2 signaling: Cytoprotective mechanism against oxidative damage Cancer Research
06/04/2012
Abstract 2593: HDAC inhibition reverses EMT through modulation of ZEB1 Cancer Research
06/04/2012
Abstract 2592: Vitamin E forms and 13'-carboxychromanol, a long-chain metabolite of {alpha}-tocopherol, induce cell death by interrupting de novo sphingolipid synthesis in human cancer cells Cancer Research
06/04/2012
Abstract 2590: A novel use of E2f and Cdk inhibitors to prevent RB-null tumours in genetically engineered models of retinoblastoma Cancer Research
06/04/2012
Abstract 2588: The effect of kava extracts and kavalactones on histone lysine methylation in urinary bladder cancer Cancer Research
06/04/2012
Abstract 2587: Proteomic and transcriptomic profiling of effects of Angelica gigas ethanol extract on prostate neuroendocrine carcinomas of TRAMP mice Cancer Research
06/04/2012
Abstract 2586: Pomegranate components modulate distinct pathways in prostate cancer cells Cancer Research
06/04/2012
Abstract 2585: Resveratrol induces autophagy in prostate cancer cells and intervention suppresses the progression of PIN in animals Cancer Research
06/04/2012
Abstract 2584: Notch1 and Notch2 activation by phenethyl isothiocyanate hinders its inhibitory effect on prostate cancer cell migration Cancer Research
06/04/2012
Abstract 2583: Green tea polyphenols cause stabilization and increased transcriptional activity of p53 by increasing its acetylation through inhibition of class I histone deacetylases Cancer Research
06/04/2012
Abstract 2581: Curcubitacin B exhibits cytotoxic effects by inhibiting ILK-Paxillin signaling in breast cancer cells Cancer Research
06/04/2012
Abstract 2580: Induction of estrogen receptor alpha by GW9662 sensitizes mammary glands to tamoxifen treatment in organ culture Cancer Research
06/04/2012
Abstract 2579: Capsaicin inhibits {beta}-catenin signaling in pancreatic cancer cells by disrupting nuclear {beta}-catenin/TCF-1 complex: critical role of STAT-3 Cancer Research
06/04/2012
Abstract 2578: Anticancer action of garcinol in vitro and in vivo is mediated through inhibition of STAT-3 signaling Cancer Research
06/04/2012
Abstract 2577: Blocking Janus activated kinase-2 activation by DIM suppresses ovarian tumor growth in vitro and in vivo Cancer Research
06/04/2012
Abstract 2576: STAT3 tyrosine phosphorylation is frequent in diffuse large B cell lymphoma and is independent of molecular subtype: Implications for biomarker Cancer Research
06/04/2012
Abstract 2575: DNA microarray and connectivity map analysis reveals estrogen-like activity of Chinese medicinal formula Si-Wu-Tang Cancer Research
06/04/2012
Abstract 2574: Mangosteen fruit extract promotes endoplasmic reticulum stress through upregulation of CHOP/GADD153 in prostate cancer cells Cancer Research
06/04/2012
Abstract 2573: Carnosol and carnosic acid, from rosemary, promote endoplasmic reticulum stress and androgen receptor degradation in prostate cancer cells Cancer Research
06/04/2012
Abstract 2572: Pro-resolving effects of 15-deoxy-{alpha}12,14-prostaglandin J2 through activation of Nrf2-mediated CD36 expression in murine macrophages Cancer Research
06/04/2012
Abstract 2571: The effect of 15-deoxy-{alpha}12,14-prostaglandin J2 on osteolytic bone metastasis by breast cancer cells Cancer Research
06/04/2012
Abstract 2570: Role of PPAR gamma in chemoprevention of renal cell carcinomas by omega-3 fatty acids Cancer Research
06/04/2012
Abstract 2569: Lyc-O-Mato causes cell cycle arrest and apoptosis in human bladder transitional carcinoma cells Cancer Research
06/04/2012
Abstract 2568: Hexane fraction of Naematoloma sublateritium extracts inhibits metastatic potential of MDA-MB-231 Breast cancer cells through modulation of the JNK and p38 pathway Cancer Research
06/04/2012
Abstract 2567: DIM regulates anoikis through sonic hedgehog in ovarian cancer cells Cancer Research
06/04/2012
Abstract 2566: Critical role of autophagy proteins Beclin 1 and LC3B in deguelin-induced apoptosis in pancreatic tumor cells in vitro and in vivo: A new paradigm Cancer Research
06/04/2012
Abstract 2564: Characterization of dysgerminoma-like cells emerged in the process of iPSC generation from common Marmoset fibroblasts Cancer Research
06/04/2012
Abstract 2563: Characterization of a p53 knockout Sprague Dawley rat Cancer Research
06/04/2012
Abstract 2562: Ultra sensitive immuno-array based multiplexed assay capable of profiling RTKs and signaling proteins, heterodimers, and growth factors for routine analysis of clinical samples with limited availability Cancer Research
06/04/2012
Abstract 2561: IKK{alpha} links inflammation and tumorigenesis in a mouse model of lung squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2560: IKK{alpha} inactivation predisposes to spontaneous lung squamous cell carcinomas Cancer Research
06/04/2012
Abstract 2559: Targeting mTORC1 may provide selectivity for inhibiting proliferation of hair follicle stem/progenitor cells during tumor promotion Cancer Research
06/04/2012
Abstract 2558: VEGF-dependent suppression of prostaglandin transporter (PGT) expression in Kras mutant human bronchial epithelial cells Cancer Research
06/04/2012
Abstract 2557: Exploring the contribution of ubiquitin binding domain of Bcr-Abl in chronic myelogenous leukemia Cancer Research
06/04/2012
Abstract 2556: Stat1 plays a major role in skin tumor promotion by chrysarobin but not TPA Cancer Research
06/04/2012
Abstract 2555: Aberrantly expressed AURKC increases tumorigenicity in cancer cells Cancer Research
06/04/2012
Abstract 2554: HSP90 inhibition induced cytotoxicity via downregulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells Cancer Research
06/04/2012
Abstract 2553: A non-catalytic function of Rev1 in translesion DNA synthesis and mutagenesis is mediated by its stable interaction with Rad5 Cancer Research
06/04/2012
Abstract 2552: Detection of PIGO-deficient cells using proaerolysin: a valuable tool to investigate mechanisms of mutagenesis in the DT40 cell system Cancer Research
06/04/2012
Abstract 2551: New understanding of cancer induction by ionizing radiation Cancer Research
06/04/2012
Abstract 2550: Expanded simple tandem repeat (ESTR) mutations in offspring of benzo(a)pyrene exposed DNA repair deficient male mice Cancer Research
06/04/2012
Abstract 2548: Quantitative changes in endogenous DNA adducts correlate with conazole mutagenicity and tumorigenicity in mouse liver Cancer Research
06/04/2012
Abstract 2547: Protein kinase C epsilon and protein kinase C delta, which are linked to skin carcinogenesis, associate with heat shock protein 90 beta Cancer Research
06/04/2012
Abstract 2546: A novel DNA damage detection assay reveals a critical role of XPF in the repair of endogenous damage Cancer Research
06/04/2012
Abstract 2544: Associations between RET/PTC rearrangements, BRAF and RAS mutations and radiation dose, age at exposure, and latency in post-Chernobyl thyroid cancer Cancer Research
06/04/2012
Abstract 2543: A dual-fluorescent reporter system facilitates identification of thiol compounds that suppress oxidative frameshift mutations Cancer Research
06/04/2012
Abstract 2542: EXO1 is required for SN1 methylator-induced DNA damage response Cancer Research
06/04/2012
Abstract 2541: Effect of carcinogen acrolein on DNA repair and mutagenic susceptibility. Cancer Research
06/04/2012
Abstract 2539: The PARP inhibitor AZD2281 induces autophagy and complete cell death in BRCA mutant breast cancer cell lines Cancer Research
06/04/2012
Abstract 2538: HIF1{alpha} regulated expression of XPA contributes to cisplatin resistance in lung cancer Cancer Research
06/04/2012
Abstract 2537: UVB irradiation induces nuclear translocation of TC-PTP in keratinocytes Cancer Research
06/04/2012
Abstract 2535: Regulation of Chk1 by the mTOR pathway is essential for cancer cells to complete DNA replication in response to replication stress Cancer Research
06/04/2012
Abstract 2534: Anti-LOXL2 conjugated gold nanoparticles: therapeutic probes for pancreatic cancer Cancer Research
06/04/2012
Abstract 2533: A novel approach to generate anti-Tn antibody for cancer diagnosis and immunotherapy Cancer Research
06/04/2012
Abstract 2532: Integrated therapeutic antibody development at the National Research Council of Canada Cancer Research
06/04/2012
Abstract 2531: Reduction of In Vivo Tumor Growth and Angiogenesis by a Humanized IgG4 Monoclonal Antibody to SEMA4D Cancer Research
06/04/2012
Abstract 2530: Long-term tumor regression induced by a novel antibody drug conjugate that targets 5T4, an oncofetal antigen expressed on tumor-initiating cells Cancer Research
06/04/2012
Abstract 2529: A monoclonal anti-Globo H antibody, VK9 can mediate CDC/ADCC and inhibit adhesion of Globo H+ cancer cells to extracellular matrix Cancer Research
06/04/2012
Abstract 2528: 3C23K: an anti-human Mullerian inhibiting substance type II receptor humanized monoclonal antibody for ovarian cancer targeted therapy Cancer Research
06/04/2012
Abstract 2527: Antibody-dependent cellular cytotoxicity of cetuximab against colorectal cancer cells with wild-type and mutant KRAS Cancer Research
06/04/2012
Abstract 2526: Optimal cleavable linker for antibody-SN-38 conjugates for cancer therapy: Impact of linker's stability on efficacy Cancer Research
06/04/2012
Abstract 2525: JL1 is a cell surface molecule of acute leukemia blasts: Potential for targeted immunotherapy Cancer Research
06/04/2012
Abstract 2524: Antibodies of the IgG and IgE classes against the melanoma-associated antigen HMW-MAA: Investigating a new therapeutic approach Cancer Research
06/04/2012
Abstract 2523: The in vitro effects of immobilized epratuzumab, a non-blocking anti-CD22 humanized monoclonal antibody, on malignant B cells Cancer Research
06/04/2012
Abstract 2522: The anti-kappa monoclonal antibody MDX-1097 cooperates with Lenalidomide to enhance antibody-dependent cell cytotoxicity of multiple myeloma cells Cancer Research
06/04/2012
Abstract 2521: Targeting CD44 in head and neck squamous cell carcinoma (HNSCC) with a new humanized antibody RO5429083 Cancer Research
06/04/2012
Abstract 2520: CHC promotes tumor growth and angiogenesis through regulation of HIF-1{alpha} and VEGF signaling Cancer Research
06/04/2012
Abstract 2519: U3-1565, a fully human anti-HB-EGF monoclonal antibody, inhibits oncogenic signaling and tumor cell growth in vitro and in vivo Cancer Research
06/04/2012
Abstract 2518: A novel preclinical study in cynomolgus monkeys examining CCL2 production rate and kinetic profile after escalating dose administration of anti-CCL2 human monoclonal antibody carlumab (CNTO 888) Cancer Research
06/04/2012
Abstract 2517: Potent antitumor activity of AbGn-ADC, a humanized monoclonal antibody conjugated with dolastatin analogue, to gastric and pancreatic cancers expressing AbGn carbohydrate epitope Cancer Research
06/04/2012
Abstract 2516: Immunohistochemical characterization of a novel, highly sensitive monoclonal antibody to folate receptor {alpha} Cancer Research
06/04/2012
Abstract 2514: CSPG4 as a target of antibody-based immunotherapy for malignant mesothelioma Cancer Research
06/04/2012
Abstract 2513: Evaluation of CD37 expression by calibrated IHC identifies non-Hodgkin's lymphoma as a therapeutic target for IMGN529, an anti-CD37-maytansinoid conjugate Cancer Research
06/04/2012
Abstract 2512: PF-04605412 induces cytokine activation and marginalization of NK cells and macrophages in patients with solid tumor Cancer Research
06/04/2012
Abstract 2511: Tumor cell-specific full-length human antibodies from Epstein-Barr virus-immortalized sentinel node B lymphocytes from breast cancer patients Cancer Research
06/04/2012
Abstract 2509: AV-203, a humanized ERBB3 inhibitory antibody inhibits ligand-dependent and ligand-independent ERBB3 signaling in vitro and in vivo Cancer Research
06/04/2012
Abstract 2508: GE-huMab-HER3, a novel humanized, glycoengineered HER3 antibody with enhanced ADCC and superior preclinical in vitro and in vivo efficacy Cancer Research
06/04/2012
Abstract 2507: Relationship between cell surface expression level of EGF-R and cetuximab-mediated ADCC activity in human colorectal cancer cells Cancer Research
06/04/2012
Abstract 2506: A phase 1 study of ABT-806, a humanized recombinant anti-EGFR monoclonal antibody, in patients with advanced solid tumors Cancer Research
06/04/2012
Abstract 2505: Targeting the p53 response in pediatric B-cell acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 2504: Defining the contribution of the extracellular domain of ICAM-2 to the non metastatic phenotype of neuroblastoma cells using chimeric fusion proteins Cancer Research
06/04/2012
Abstract 2503: Multicellular Ewing sarcoma spheres are efficiently targeted by activated NK cells Cancer Research
06/04/2012
Abstract 2502: Next-generation sequencing: Integrated exotome analysis in human multiple neuroblastoma Cancer Research
06/04/2012
Abstract 2501: Inhibition of the PI3K pathway potentiates temozolomide effects in pediatric glioblastoma and results in alterations in glucose and choline metabolism detected by MRS Cancer Research
06/04/2012
Abstract 2500: The pivotal role of p53 in doxorubicin-induced acute versus chronic cardiotoxicity Cancer Research
06/04/2012
Abstract 2499: The significance of Wip1 in neuroblastoma and medulloblastoma Cancer Research
06/04/2012
Abstract 2498: Differential rapamycin sensitivity distinguishes two distinct populations of tumor cells in murine glioma Cancer Research
06/04/2012
Abstract 2497: ET-743 interferes with EWS-FLI1 driven WRN expression in Ewing sarcoma cells and sensitizes to topoisomerase I inhibitors Cancer Research
06/04/2012
Abstract 2496: Characterization of genes critical for chondro-osseous differentiation, metastasis and osteotropism in Ewing Tumors Cancer Research
06/04/2012
Abstract 2495: Sepiapterin reductase interacts with Ornithine Decarboxylase and regulates neuroblastoma proliferation Cancer Research
06/04/2012
Abstract 2494: Identification of mithramycin analogues with increased potency and more selective inhibition of EWS-FLI1 for the treatment of Ewing sarcoma Cancer Research
06/04/2012
Abstract 2493: Enhanced activity of fenretinide/-LYM-X-SORBTM (4-HPR/LXS) oral powder in combination with ketoconazole and vincristine against recurrent neuroblastoma xenografts Cancer Research
06/04/2012
Abstract 2492: Integrated genomics on molecular subgroups in medulloblastoma Cancer Research
06/04/2012
Abstract 2491: High-dose acetaminophen with N-acetylcysteine rescue enhances the efficacy of cisplatin chemotherapy Cancer Research
06/04/2012
Abstract 2490: High AXL promotes migration in non-MYCN amplified neuroblastoma cell lines Cancer Research
06/04/2012
Abstract 2489: A phase II trial of poly-ICLC in the management of recurrent or progressive pediatric low grade gliomas Cancer Research
06/04/2012
Abstract 2488: Reovirus (Reolysin) as a potential therapy for malignant peripheral nerve sheath tumors Cancer Research
06/04/2012
Abstract 2487: CONSERTING: an accurate method for detecting focal and gross somatic copy number alterations in cancer genome by next generation sequencing Cancer Research
06/04/2012
Abstract 2486: African ancestry is associated with high-risk disease and event-free survival in children with neuroblastoma Cancer Research
06/04/2012
Abstract 2485: Combined Src and aurora kinase inhibition in medulloblastoma Cancer Research
06/04/2012
Abstract 2484: Whole-exome sequencing of a rare case of familial childhood acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 2483: Inhibition of the polycomb group gene EZH2 suppresses growth and radiosensitizes ATRT cells by promoting senescence and inhibiting the CycinD-E2F1 axis Cancer Research
06/04/2012
Abstract 2465: Matrix metalloproteinase 9 promotes breast cancer through regulation of insulin-like growth factor-binding proteins Cancer Research
06/04/2012
Abstract 2464: Novel MMP-3 generated PTHrP peptides promote osteoblast proliferation: Implications for prostate to bone metastases Cancer Research
06/04/2012
Abstract 2462: Pro-tumorigenic activity of plasminogen activtor inhibitor-1 through an anti-apoptotic function Cancer Research
06/04/2012
Abstract 2460: Extracellular matrix protein expression is associated with chemotherapy resistance in breast cancer Cancer Research
06/04/2012
Abstract 2458: The expression of hyaluronan and hyaluronidases in cutaneous melanoma Cancer Research
06/04/2012
Abstract 2457: Laminin receptor cross-talk stimulates receptor internalization and migration of human prostate cancer cells Cancer Research
06/04/2012
Abstract 2456: TGF-Beta regulates tumor ECM remodeling and progression to metastasis Cancer Research
06/04/2012
Abstract 2455: Molecular targeted imaging of vascular endothelial growth factor receptor (VEGFR)-2 and anti-NMP autoantibodies detect ovarian tumor at early stage Cancer Research
06/04/2012
Abstract 2452: Tumor detection and measurement of responses to chemotherapy using human phosphatidylserine targeting antibody fragments Cancer Research
06/04/2012
Abstract 2451: Development of a high performance liquid chromatography (HPLC) method for controlling the radiochemical purity (RCP) of 99mTc-tetrofosmin used in oncology Cancer Research
06/04/2012
Abstract 2450: Optimization of spontaneous metastasis incidence and quantification in human tumor xenograft models using bioluminescence imaging Cancer Research
06/04/2012
Abstract 2447: Measurement of tumor vascular integrity changes in an orthotopic glioma model in rats induced by antiangiogenic treatment using DCE-MRI Cancer Research
06/04/2012
Abstract 2445: High-resolution imaging of orthotopic glioblastoma in mice using multispectral optoacoustic tomography Cancer Research
06/04/2012
Abstract 2444: Non-invasive FMT quantification of folate receptor expression in mouse tumor xenografts with a new near-infrared fluorescent folate agent Cancer Research
06/04/2012
Abstract 2443: MR imaging in human glioma tumor xenograft models using enzyme-conjugated anti-EGFRvIII-specific antibody fragments Cancer Research
06/04/2012
Abstract 2442: A precise orthotopic rectal tumor model for evaluating therapeutic response of cancer treatment Cancer Research
06/04/2012
Abstract 2441: Modeling glioblastoma in the mouse: Insights from noninvasive imaging Cancer Research
06/04/2012
Abstract 2440: Glioblastoma molecular imaging in vivo using multi-spectral optoacoustic tomography Cancer Research
06/04/2012
Abstract 2439: Molecular imaging of spatial and temporal heterogeneity of tumor micro-environment in mouse models of non-small cell lung cancer macroscopic xenografts and micro-metastases Cancer Research
06/04/2012
Abstract 2438: Bevacizumab treatment hampers tumor uptake of antibodies in human tumor bearing mice Cancer Research
06/04/2012
Abstract 2436: [18F]FDG accumulation in tumor microenvironment -Microautoradiographic study combined with immunohistochemistry in mice- Cancer Research
06/04/2012
Abstract 2435: Assessment of vascular disrupting properties of sodium meta-arsenite treatment using Dynamic contrast-enhanced MRI in colon cancer allograft model Cancer Research
06/04/2012
Abstract 2433: Comparisons between an IRDye 800CW-labeled PSMA-targeted small molecule and antibody for preclinical small animal imaging Cancer Research
06/04/2012
Abstract 2431: 89Zr-bevacizumab PET as an early biomarker for response to everolimus treatment in an ovarian cancer xenograft model Cancer Research
06/04/2012
Abstract 2430: PET imaging of c-Met expression in non-human primates using [18F]AH113804 Cancer Research
06/04/2012
Abstract 2429: An abdominal imaging window for long-term subcellular visualization of abdominal organs in living mice Cancer Research
06/04/2012
Abstract 2428: Echo-contrast monitoring of sorafenib early efficacy: animal model for Ewing's sarcoma tumors Cancer Research
06/04/2012
Abstract 2427: The stress response controls the interorgan glutathione/interleukin-6 cycling activity: A systemic signaling mechanism promoting metastases growth. Cancer Research
06/04/2012
Abstract 2426: Role of fibroblast growth factor receptor 1 (FGFR1) in liver metastasis of colorectal cancer Cancer Research
06/04/2012
Abstract 2425: Collapsin response mediator protein 4 promotes tumor cell invasion and lethality of pancreatic cancer Cancer Research
06/04/2012
Abstract 2424: Conditioned media enhances proliferation and mobility in triple negative breast cancer cells Cancer Research
06/04/2012
Abstract 2423: Acute in vitro exposure to cigarette smoke particulate matter does not induce epithelial-mesenchymal transition in lung epithelial cells Cancer Research
06/04/2012
Abstract 2421: Iron deficiency suppresses EMT through down-regulation of N-cadherin in esophageal cancer. Cancer Research
06/04/2012
Abstract 2420: Loss of hCLCA4 promotes EMT in breast cancer Cancer Research
06/04/2012
Abstract 2419: Irradiation of {alpha}-ionizing radiation to in vivo glioma model induced metastasis via occurrence of epithelial-mesenchymal transition Cancer Research
06/04/2012
Abstract 2418: NADPH Oxidase 1 over-expression enhances invasion via matrix metalloproteinase-2 and epithelial-mesenchymal transition in melanoma cells Cancer Research
06/04/2012
Abstract 2417: Oncogenic properties shared by all Snail family members Cancer Research
06/04/2012
Abstract 2415: Phenotypic stabilization of mesenchymal-like cancer cells through mesenchymal-specific DNA hypermethylation Cancer Research
06/04/2012
Abstract 2414: The inhibitory effect of heat treatment against Epithelial-Mesenchymal Transition (EMT) in human colon adenocarcinoma cell line Cancer Research
06/04/2012
Abstract 2413: Human glypican-3 promotes hepatocellular carcinoma progression via induction of epithelial-mesenchymal transition Cancer Research
06/04/2012
Abstract 2412: Epithelial splicing regulatory protein 1 modulates cell growth, migration, and invasion of human pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 2411: The epithelial-mesenchymal transition of gastric cancer cells was stimulated by TGF{beta}R signaling in hypoxia Cancer Research
06/04/2012
Abstract 2410: Reduced expression of DDB2 promotes epithelial to mesenchymal transition in colon cancer Cancer Research
06/04/2012
Abstract 2409: Pharmacologic ascorbate inhibits pancreatic cancer cell EMT and sensitizes cancer cells to gemcitabine Cancer Research
06/04/2012
Abstract 2408: CD44s is required for a tumor-initiating stem-like mesenchymal phenotype in hepatocellular carcinoma via ligand-independent c-Met activation Cancer Research
06/04/2012
Abstract 2407: Snail 1 regulates invasion through uPA-uPAR and MMP-9 signaling in prostate cancer cells Cancer Research
06/04/2012
Abstract 2405: Loss of TBK1 induces an epithelial-mesenchymal transition through upregulation of Slug in the breast cancer cell lines Cancer Research
06/04/2012
Abstract 2404: Correlation of OGlcNAc modification components and EMT/Stem cell markers in lung adenocarcinoma Cancer Research
06/04/2012
Abstract 2403: DNAJB6 suppresses the Wnt/{beta}-catenin pathway Cancer Research
06/04/2012
Abstract 2402: TGF beta-mediated epithelial to mesenchymal transition in non small cell lung cancer: effects on stemness, invasiveness and chemotherapy sensitivity Cancer Research
06/04/2012
Abstract 2401: Epigenetics-regulated microRNAs related with epithelial-mesenchymal transition of breast cancer cells Cancer Research
06/04/2012
Abstract 2400: Epithelial-mesenchymal transition in hepatocellular carcinoma leads to downregulation of adaptive immunity via COX-2 pathway Cancer Research
06/04/2012
Abstract 2399: Syntenin-1 promotes cell invasion though regulating Slug-dependent epithelial-mensenchymal transition in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 2398: S100P/RAGE signaling activates AP1 and NF-kB in miR-21/RECK regulation Cancer Research
06/04/2012
Abstract 2397: Evaluation of proliferation and apoptosis markers in circulating tumor cells (CTCs) of women with early breast cancer who are candidates for tumor dormancy Cancer Research
06/04/2012
Abstract 2395: HER-2 FISH analysis and H & E staining of circulating tumor cells pre-isolated using high porosity precision microfilters Cancer Research
06/04/2012
Abstract 2393: Isolation and characterization of circulating tumor cells in a mouse model of colorectal cancer Cancer Research
06/04/2012
Abstract 2392: A novel approach for detecting viable and tissue-specific circulating tumor cells Cancer Research
06/04/2012
Abstract 2391: All patients with metastatic breast, colorectal and prostate carcinoma have circulating tumor cells Cancer Research
06/04/2012
Abstract 2390: Increased detection of circulating prostate epithelial tumor cells on microfluidic channels using enhanced staining and automated scanning Cancer Research
06/04/2012
Abstract 2389: A microfluidic system for the selection of circulating tumor cells that utilizes both affinity and size capture technologies Cancer Research
06/04/2012
Abstract 2388: Dendrimer-mediated multivalent binding strongly captures tumor cells Cancer Research
06/04/2012
Abstract 2387: Analysis of the expression of stemness and epithelial-to-mesenchymal transition markers in circulating tumor cells of patients with breast cancer Cancer Research
06/04/2012
Abstract 2386: Triple fluorescence analysis of estrogen receptor alpha (ER) and ErbB2 status of circulating tumor cells (CTC) in breast cancer: from cell models to metastatic patients Cancer Research
06/04/2012
Abstract 2385: A highly sensitive detection system of genetic alterations in circulating tumor cells using a telomerase-specific replication-competent adenovirus Cancer Research
06/04/2012
Abstract 2384: Assessment of PITX2, BMP4, FGF4, ERalpha, ERbeta promoter methylation in the circulating tumor cells (CTCs) can predict metastasis and survival in primary invasive duct carcinoma (PIDC) patients Cancer Research
06/04/2012
Abstract 2383: A new approach to isolate label-free and viable circulating tumor cells for monitoring cancer patient treatment response Cancer Research
06/04/2012
Abstract 2382: SOX17 promoter methylation in CTC and cell free DNA isolated from plasma of breast cancer patients Cancer Research
06/04/2012
Abstract 2381: ApoStreamtm, an antibody independent platform, captures circulating tumor cells in patients with hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 2380: Detecting human circulating endothelial cells using the acoustic focusing cytometer Cancer Research
06/04/2012
Abstract 2378: Detection of circulating tumors cells (CTCs) in mice, using cancer stem cell (CSC) markers and a novel cell surface marker, AnnexinA2 Cancer Research
06/04/2012
Abstract 2376: Development of a novel microfluidic device for the capture and molecular characterization of circulating tumor cells from metastatic breast cancer patients Cancer Research
06/04/2012
Abstract 2375: Rapid unbiased enrichment (negative selection) of circulating non-hematopoietic tumor cells directly from whole blood Cancer Research
06/04/2012
Abstract 2373: An integrated approach for isolating CTCs to enable the interrogation of cellular heterogeneity using IFAST Cancer Research
06/04/2012
Abstract 2372: Capture and molecular characterization of CTC in metastatic breast, prostate, colorectal, and renal cancer Cancer Research
06/04/2012
Abstract 2371: Circulating cancer associated cells co-express epithelial and hematopoietic markers in metastatic breast cancer (MBC) patients (pts) Cancer Research
06/04/2012
Abstract 2370: Development of microcavity array system for size- and deformability-based isolation of circulating tumor cells Cancer Research
06/04/2012
Abstract 2369: Correlating circulating tumor cells with 18F-FDG positron emission tomography (PET) uptake in patients with treatment naive non-small cell lung cancer: A pilot study Cancer Research
06/04/2012
Abstract 2368: Unbiased quantitative assessment of Her-2 expression of circulating tumor cells in patients with metastatic and non metastatic breast cancer Cancer Research
06/04/2012
Abstract 2367A: Understanding the role of stem-like tumor cells in mouse models of high-grade gliomas Cancer Research
06/04/2012
Abstract 2367: Neural progenitor cells deficient in BAX and BAK manifest progressive hyperplasia and tumorigenesis Cancer Research
06/04/2012
Abstract 2366: Role of MKP1 in skin carcinogenesis Cancer Research
06/04/2012
Abstract 2365: Defining the role of Akt activation in melanoma development and progression Cancer Research
06/04/2012
Abstract 2364: Identification of therapy resistant pediatric brain tumor cells that have extraordinary survival and tumorigenic capabilities: The ultimate seed cells that drives the growth of autopsied tumor cells in mouse brains Cancer Research
06/04/2012
Abstract 2363: Comparison and characterization of two orthotopic glioblastoma in vivo mouse models with human U87 and LN-229 cells using in vivo bioluminescence imaging and magnetic resonance imaging (MRI) Cancer Research
06/04/2012
Abstract 2362: Targeted suppression of TGF-beta2 by trabedersen (AP 12009) in an orthotopic xenograft melanoma mouse model Cancer Research
06/04/2012
Abstract 2360: Complex DNA damage cooperates with Ink4a/Ink4b/Arf loss to generate high grade gliomas in transgenic mouse models Cancer Research
06/04/2012
Abstract 2359: Using the glycolytic inhibitor 2-fluorodeoxy-D-glucose, a novel glycolytic inhibitor approach to target the chemoresistant, hypoxic cell population in advanced LHBETATAG retinal tumors Cancer Research
06/04/2012
Abstract 2358: ERK1/2 regulation of CD44 modulates aggressiveness in a new mouse model of oral cancer Cancer Research
06/04/2012
Abstract 2356: Establishment of HPV-positive and HPV-negative head and neck cancer tumorgrafts directly from patient biopsies Cancer Research
06/04/2012
Abstract 2355: Assessment of glioma recurrence following radiotherapy using the parametric response map: A preclinical study Cancer Research
06/04/2012
Abstract 2354: A neural origin for intracranial germ cell tumors Cancer Research
06/04/2012
Abstract 2353: Therapeutic effect of cilengitide in combination with CKD-602, a campothecin derivative, against experimental glioblastoma Cancer Research
06/04/2012
Abstract 2352: Molecular profiles of head and neck cancer tumorgrafts Cancer Research
06/04/2012
Abstract 2351: Identification of somatic mutations in esophageal squamous cell carcinoma and corresponding xenograft by next-generation sequencing Cancer Research
06/04/2012
Abstract 2350: DATS prevented tumor progression and induced apoptotic death in an ectopic model of glioblastoma in SCID mice Cancer Research
06/04/2012
Abstract 2349: Establishment of a novel metastatic head and neck cancer model with gain of epithelial-mesenchymal transition and stemness properties Cancer Research
06/04/2012
Abstract 2348: Suppression of metastasis of intratesticular inoculation of B16FO melanoma cells by a novel nutrient mixture in male athymic nude mice Cancer Research
06/04/2012
Abstract 2347: Translational control and lung cancer: eIF4F activation promotes tumorigenesis in vivo Cancer Research
06/04/2012
Abstract 2346: Lung cancer progression by efficient cre-mediated deletion of Pten and Smad4 Cancer Research
06/04/2012
Abstract 2344: PDX from the naive NSCLC patients containing activating EGFR mutations are resistant to erlotinib but sensitive to c-met inhibitor Cancer Research
06/04/2012
Abstract 2343: Establishment of patients' primary non-small cell lung cancer xenograft models for test of anticancer drugs Cancer Research
06/04/2012
Abstract 2341: Curcumin targets a stem-like subpopulation of Lewis lung carcinoma cells Cancer Research
06/04/2012
Abstract 2339: Specific binding of modified ZD 6474 (Vandetanib) monomer and its dimer with VEGF receptor 2 Cancer Research
06/04/2012
Abstract 2338: Aflibercept (VEGF Trap) impairs tumor growth and perfusion, and restrains metastasis invasion in orthotopic models Cancer Research
06/04/2012
Abstract 2337: Regorafenib (BAY 73-4506): Anti-metastatic activity in a mouse model of colorectal cancer Cancer Research
06/04/2012
Abstract 2334: Anti-angiogenic activity of anthrax lethal toxin using the mouse retina as a model system Cancer Research
06/04/2012
Abstract 2332: The glucose analog 2-DG selectively inhibits AKT and ERK in endothelial cells via interference of N-linked glycosylation and induces endothelial cell apoptosis in vitro and in vivo. Cancer Research
06/04/2012
Abstract 2330: Murine interferon-{alpha} inhibits aortic endothelial outgrowth Cancer Research
06/04/2012
Abstract 2329: Anti-tumor efficacy of Dll4 blockade in combination with sunitinib or aflibercept in primary human renal cell carcinoma models Cancer Research
06/04/2012
Abstract 2328: Targeting angiogenesis: Anti-docking site peptides to Met receptor and nanotechnology Cancer Research
06/04/2012
Abstract 2327: Anti-angiogenic activity of a CovX bi-functional antibody conjugate targeting both activin-receptor like kinase type 1 (ALK-1) and vascular endothelial growth factor (VEGF) Cancer Research
06/04/2012
Abstract 2325: Increase in neuroblastoma metastasis after dual inhibition of VEGF and Notch Cancer Research
06/04/2012
Abstract 2324: LHT-7 as multi-targeting and anti-angiogenic agent to growth factor receptors Cancer Research
06/04/2012
Abstract 2323: Iron chelator contributes to anti-angiogenic therapy via selective induction of VEGF-A Cancer Research
06/04/2012
Abstract 2322: Rapid discovery of novel antiangiogenic drugs using a phenotypic profiling platform with high predictive value for preclinical models of cancer Cancer Research
06/04/2012
Abstract 2321: The novel vasopressin analog [4-valine 5-glutamine] desmopressin inhibits tumor growth and angiogenesis in V2 receptor-expressing breast cancer xenografts Cancer Research
06/04/2012
Abstract 2320: A multi-domain fusion molecule inhibits tumor growth affecting in-vivo angiogenesis Cancer Research
06/04/2012
Abstract 2319: Dual inhibition of Ang-2 and VEGF via a novel human bispecific bivalent IgG1 CrossMAb shows potent anti-angiogenic, antitumoral, and antimetastatic efficacy and leads to a reduced side effect profile compared to single therapies Cancer Research
06/04/2012
Abstract 2318: Azadirachta indica leaf extract attenuates angiogenesis in endothelial cells Cancer Research
06/04/2012
Abstract 2317: Direct anti-angiogenic activity of a small molecular STAT3 inhibitor LLL12 Cancer Research
06/04/2012
Abstract 2316: Itraconazole, an antifungal drug with anti-angiogenic activity, inhibits VEGFR2 trafficking, glycosylation, and signaling in endothelial cells Cancer Research
06/04/2012
Abstract 2315: Pharmacodynamic and antitumor activity of fragment-derived inhibitors of MetAP2 in tumor xenografts Cancer Research
06/04/2012
Abstract 2314: Dovitinib demonstrates antitumor and anti-metastatic activities in xenograft models of hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 2312: A genomics approach to determining the role of DICER1 in tumorigenesis: Interferon responses in the cancer cell Cancer Research
06/04/2012
Abstract 2311: microRNA-196b regulates HOXB7 in cervical cancer Cancer Research
06/04/2012
Abstract 2310: Identification of signaling pathways involved in the regulation of let-7 in ovarian cancer Cancer Research
06/04/2012
Abstract 2309: Down-regulation of miR-181b contributes to the poor prognosis of adverse cytogenetically abnormal acute myeloid leukemia by targeting PBX3 Cancer Research
06/04/2012
Abstract 2307: MiR-365 regulates lung cancer and developmental gene TTF-1 Cancer Research
06/04/2012
Abstract 2306: Overexpression of microRNA-223 regulates the ubiquitin ligase FBXW7 in esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2482: Carnitine palmitoyltransferase 1A (CPT1A): a transcriptional target of PAX3-FKHR and mediates PAX3-FKHR-dependent motility in alveolar rhabdomyosarcoma cells Cancer Research
06/04/2012
Abstract 2481: Exploiting BRAF mutation for therapy of childhood low-grade astrocytoma Cancer Research
06/04/2012
Abstract 2480: High-level activation of the Notch pathway in diffuse intrinsic pontine glioma Cancer Research
06/04/2012
Abstract 2479: TP53 status as a marker of recurrence and survival in choroid plexus carcinomas Cancer Research
06/04/2012
Abstract 2478: Jagged 2 signalling is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells Cancer Research
06/04/2012
Abstract 2476: P53 is potential predictive biomarker for combination therapy of epidermal growth factor receptor (EGFR) and MET inhibitors in non-small cell lung cancer (NSCLC) with wild-type EGFR Cancer Research
06/04/2012
Abstract 2475: The abundance of SLC7a11 transporter in different tissues Cancer Research
06/04/2012
Abstract 2474: Microenvironments of tumor cell intravasation Cancer Research
06/04/2012
Abstract 2473: Extracellular matrix density and acinus formation in breast cancer Cancer Research
06/04/2012
Abstract 2471: The role of Syndecan 1 and 4 in breast cancer brain metastasis Cancer Research
06/04/2012
Abstract 2470: Adhesion-mediated dysfunctions in myelodysplastic syndromes microenvironment Cancer Research
06/04/2012
Abstract 2468: Inhibition of autophagy as a potential mechanism by which pantoprazole, a proton pump inhibitor (PPI), enhances the therapeutic effect of docetaxel chemotherapy for solid tumors Cancer Research
06/04/2012
Abstract 2467: Acidic pericellular pH increases contribution of cathepsin B to invasiveness of a human breast carcinoma cell line Cancer Research
06/04/2012
Abstract 2466: Elafin, a serine protease inhibitor, is deregulated during breast cancer progression Cancer Research
06/04/2012
Abstract 2104: Molecular alterations in JAK1 and JAK2 genes in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2103: High resolution melting analysis: a sensitive screening method for the detection of MDM2 promotor SNP309 Cancer Research
06/04/2012
Abstract 2102: High resolution fluorescence imaging of cellular DNA and RNA enabled by the synthesis of complex oligonucleotide libraries Cancer Research
06/04/2012
Abstract 2099: RNA from brush cytology to noninvasively screen for oral squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2098: Reducing sequence artefacts from FFPE DNA for cancer diagnostics Cancer Research
06/04/2012
Abstract 2097: In situ mutation detection in cancer tissue sections for research and diagnostics in clinical oncology Cancer Research
06/04/2012
Abstract 2096: Variants of uncertain clinical significance in cancer predisposition genes: Development of a family studies program for reclassification Cancer Research
06/04/2012
Abstract 2094: Comparing exome with whole-genome next-generation sequencing in detecting somatic mutations Cancer Research
06/04/2012
Abstract 2091: Ultrasensitive detection of mutations in the androgen receptor gene by ICE COLD-PCR Cancer Research
06/04/2012
Abstract 2090: Mutational analysis in circulating tumor cells (CTC):ScreenCell MB Filtration Unit and ICE COLD-PCR Cancer Research
06/04/2012
Abstract 2089: Fully automated SNP detection from whole blood and mutation detection from plasma-free DNA Cancer Research
06/04/2012
Abstract 2088: Detection of PIK3CA somatic mutations in cell-free DNA of breast cancer patients by high-resolution melting curve analysis Cancer Research
06/04/2012
Abstract 2087: Detection of KRAS mutations in circulating tumor cells (CTCs) and in formalin-fixed, paraffin-embedded (FFPE) tissue using castPCR method Cancer Research
06/04/2012
Abstract 2086: Evaluation of a promoter methylation panel in plasma cell-free DNA to screen for colorectal cancer in Hispanics Cancer Research
06/04/2012
Abstract 2085: MMP-2 knockdown leads to anoikis and inhibits migration and invasion by attenuating {alpha}v{beta}3/EGFR/Pak4 survival signaling in human glioma xenograft cells in vitro and in vivo Cancer Research
06/04/2012
Abstract 2084: Claudin-1 induces resistance to anoikis in Src dependent manner in colon cancer cells Cancer Research
06/04/2012
Abstract 2083: The regulation of anoikis by carcinoma-associated fibroblasts in breast cancer cells Cancer Research
06/04/2012
Abstract 2082: The role of cell-cell contacts in the survival of extracellular matrix detached mammary epithelial cells Cancer Research
06/04/2012
Abstract 2081: Mechanisms of the acquisition of anoikis resistance in breast cancer: Lessons from small molecule inhibitors Cancer Research
06/04/2012
Abstract 2080: The role of ErbB2 in regulating survival in matrix-detached inflammatory breast cancer cells Cancer Research
06/04/2012
Abstract 2078: Treatment with auranofin induces oxidative and lethal endoplasmic reticulum (ER) stress exerting single agent activity against mantle cell lymphoma cells Cancer Research
06/04/2012
Abstract 2077: Modulation of reactive oxygen species (ROS) by a dietary agent for the prevention/ treatment of breast cancer Cancer Research
06/04/2012
Abstract 2076: Oxidative stress induced by sodium ascorbate:menadione sodium-bisulfate combination results in lysosomal and mitochondrial changes that lead to prostate cancer cell death Cancer Research
06/04/2012
Abstract 2075: Overexpression of the peroxiredoxin family of antioxidant proteins in MCF7 breast cancer cells and investigation of possible regulatory mechanisms Cancer Research
06/04/2012
Abstract 2072: Distinct antioxidant profiles of human prostate carcinoma cell lines and tissues: Implications for rational design of redox therapy Cancer Research
06/04/2012
Abstract 2071: Docosahexaenoic acid-induced apoptosis is directly linked to mitochondria-mediated reactive oxygen species production in human cervical cancer cells Cancer Research
06/04/2012
Abstract 2070: Obesity, p53 and increased oxidative stress: The role of TXNIP Cancer Research
06/04/2012
Abstract 2068: Opposite effects of arsenic trioxide on the Nrf2 pathway in oral squamous cell carcinoma in vitro and in vivo Cancer Research
06/04/2012
Abstract 2066: Identification of NRF2 target genes in human cells: Aldoketo reductases as a potential biomarker for NRF2 activity Cancer Research
06/04/2012
Abstract 2065: Loss of Nrf2 increases susceptibility to radiation induced bone loss Cancer Research
06/04/2012
Abstract 2064: Atm is required for homeostasis within the lactating mammary gland Cancer Research
06/04/2012
Abstract 2063: Oxidized ATM functions in intracellular redox regulation Cancer Research
06/04/2012
Abstract 2062: Peptidylprolyl cis/trans isomerase A1 (Pin1) is modified by lipid electrophiles generated during oxidative stress Cancer Research
06/04/2012
Abstract 2061: Implication of NQO1 knockdown on prostate carcinogenesis Cancer Research
06/04/2012
Abstract 2060: NADPH oxidase NOX5 regulates the expression of the cell cycle inhibitor p27kip1 in the human melanoma UACC-257 cancer cells Cancer Research
06/04/2012
Abstract 2059: NADPH Oxidase 4 induced ROS regulates anoikis resistance through activation of Src and EGFR. Cancer Research
06/04/2012
Abstract 2058: Colorectal cancer in the setting of inflammatory bowel disease: role of hemoglobin Cancer Research
06/04/2012
Abstract 2057: Tumor suppressor effects of tetrahydrobiopterin are mediated through beta-catenin in breast cancer cells Cancer Research
06/04/2012
Abstract 2055: p21CIP1 mediates reciprocal switching between invasion and proliferation during metastasis Cancer Research
06/04/2012
Abstract 2053: Aurora-A kinase is required for rapid establishment of the mitotic checkpoint Cancer Research
06/04/2012
Abstract 2052: Regulation of p16Ink4a - Rb pathway by Cyclin D1- Dmp1 interaction Cancer Research
06/04/2012
Abstract 2050: Plk1 phosphorylation of Orc2 promotes DNA replication under conditions of stress Cancer Research
06/04/2012
Abstract 2049: Preclinical profile of AMG900 in combination with HDACIs in prostate cancer Cancer Research
06/04/2012
Abstract 2048: Phosphorylation and regulation of PTEN by Polo-like kinase 1 Cancer Research
06/04/2012
Abstract 2047: The interaction of ZSCAN4 with TRF1: Effects on regulation of telomere elongation in cancer cells Cancer Research
06/04/2012
Abstract 2044: Three-dimensional nuclear telomeric architecture defines cytopenias of myelodysplastic syndrome and its transformation to acute myeloid leukemia Cancer Research
06/04/2012
Abstract 2043: Deregulated Cdc7/Dbf4 expression promotes DNA repair and checkpoint recovery to enhance survival and associates with poor prognosis in OSCC Cancer Research
06/04/2012
Abstract 2042: The RAX/PACT-PKR stress-signaling pathway promotes p53 sumoylation and stability to induce G1 arrest Cancer Research
06/04/2012
Abstract 2041: Her2/Neu has an essential role for the gamma-irradiation-induced ERK1/2 signaling activation and G2/M checkpoint response Cancer Research
06/04/2012
Abstract 2038: Aurora A and BRCA1 cooperate to control cytokinesis failure leading to aneuploidy in ovarian cystadenoma cells Cancer Research
06/04/2012
Abstract 2036: Forced activation of Cdk1 via Wee-1 inhibition impairs homologous recombination in breast cancer cells Cancer Research
06/04/2012
Abstract 2035: The effect of KLF5 on cell cycle progression depends upon p53 status Cancer Research
06/04/2012
Abstract 2034: The Fbw7 tumor suppressor: Genetic and biochemical approaches to study a dimeric ubiquitin ligase Cancer Research
06/04/2012
Abstract 2033: Protection of quiescent fibroblasts from proteasome inhibition-mediated proteotoxicity Cancer Research
06/04/2012
Abstract 2032: A novel function of WW domain binding protein 2 (WBP2) in regulating cytoskeletal function and cellular division through binding to co-chaperone BAG3 Cancer Research
06/04/2012
Abstract 2029: Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer Cancer Research
06/04/2012
Abstract 2028: Kruppel-like factor 4 null mouse embryonic fibroblasts exhibit DNA repair defects post exposure to gamma-irradiation Cancer Research
06/04/2012
Abstract 2027: Carbamylated albumin increase MMP9 activity via ERK MAPK pathway Cancer Research
06/04/2012
Abstract 2026: Targeted delivery of therapeutic NefM1 peptide with single-walled carbon nanotubes (SWNTs) suppresses growth of 3-D cultures of breast and colon cancers Cancer Research
06/04/2012
Abstract 2025: Blockade of the Shh pathway by KAAD-Cyclopamine promoted apoptosis in estrogen treated breast cancer cells Cancer Research
06/04/2012
Abstract 2023: The role of RASSF1A in FasL expression and function Cancer Research
06/04/2012
Abstract 2022: P53-dependent thrombocytopenia induced by the histone deacetylase inhibitor S78454 Cancer Research
06/04/2012
Abstract 2020: Suppression of Twist expression sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin Cancer Research
06/04/2012
Abstract 2018: Discovery of potent dual inhibitors of both XIAP and cIAP1 using fragment based drug discovery Cancer Research
06/04/2012
Abstract 2017: Galectin-3 SNP rs10148371 in the anti-death motif NWGR is related to the colon cancer incidence in African Americans Cancer Research
06/04/2012
Abstract 2014: IRF8 regulates Bax transcription in primary myeloid cells differentiation and pathogenesis in CML Cancer Research
06/04/2012
Abstract 2013: Interferon gamma receptor 2 (IFNgR2) has a ligand (IFNg)-independent activity as a Bax inhibitor in cancer cells Cancer Research
06/04/2012
Abstract 2012: MAP kinase activation and suppression of anti-apoptotic Bcl-2 family members are associated with induction of apoptotic death in melanoma cells following down-regulation of glutathione S-transferase P1 Cancer Research
06/04/2012
Abstract 2011: A novel bcl-2/xL inhibitor induces tumor cell apoptosis and potentiates the activity of standard chemotherapeutics Cancer Research
06/04/2012
Abstract 2010: Development of a cytotoxic peptide based on the C-terminal domain of Bax Cancer Research
06/04/2012
Abstract 2009: PKR induces apoptosis via PP2A activation and Bcl-2 dephosphorylation in IL-3 dependent murine bone marrow stem/progenitor cells Cancer Research
06/04/2012
Abstract 2008: Broad spectrum BH3 mimetic BI-97D6 induces apoptosis of acute myeloid leukemia cells even when co-cultured with supporting stromal cells Cancer Research
06/04/2012
Abstract 2007: Differential roles of BCL-XL and BCL-2 in protecting mitochondria against oxidative stress in CML cells Cancer Research
06/04/2012
Abstract 2006: Identification and molecular cloning of novel splicing variants of BCL2L12, a new member of the BCL2 family, and their expression analysis in breast, prostate, and colon cancer cells Cancer Research
06/04/2012
Abstract 2005: Identification of Bcl2L13 as a novel GBM oncoprotein Cancer Research
06/04/2012
Abstract 2004: Ribonucleotide reductase subunit M2 regulates Bcl-2 in human cancer: A potential target for cancer therapy Cancer Research
06/04/2012
Abstract 2003: STAT3 is a critical mediator of the pro-survival effect of Bcl-2-Rac1 interaction in human cancer cells Cancer Research
06/04/2012
Abstract 2002: OCT-3/4 expression is associated with high levels of the pro-apoptotic BH3 only protein NOXA in testicular germ cell tumors (TGCTs) Cancer Research
06/04/2012
Abstract 2001: Caffeic acid phenethyl ester inhibits growth of human lung adenocarcinoma cells with an epidermal growth factor receptor T790M mutation susceptible property Cancer Research
06/04/2012
Abstract 2000: Curcumin prevents human prostate cancer cell invasion by inhibiting of matriptase activity Cancer Research
06/04/2012
Abstract 1999: Specific pomegranate juice components are potential inhibitors of prostate cancer metastasis Cancer Research
06/04/2012
Abstract 1998: Inhibition of hedgehog signaling in prostate cancer by extracts of Sutherlandia Cancer Research
06/04/2012
Abstract 1997: Resveratrol modifies the activity and expression of antioxidant enzymes in somatic cancer cells Cancer Research
06/04/2012
Abstract 1996: Anticancer efficacy and mechanism of action of novel ginsenoside 25-OCH3-PPD, a natural product MDM2 inhibitor Cancer Research
06/04/2012
Abstract 1995: Huachansu inhibits proliferation of non-hodgkin lymphoma cells by induction of apoptosis Cancer Research
06/04/2012
Abstract 1994: Honokiol reduces drug resistance by down-regulation of survivin expression in multidrug resistant squamous cell carcinoma of the head and neck Cancer Research
06/04/2012
Abstract 1993: Fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells Cancer Research
06/04/2012
Abstract 1992: Ganoderma lucidum (Reishi) induces autophagy in inflammatory breast cancer by regulation of the mTOR signaling pathway Cancer Research
06/04/2012
Abstract 1991: Effects of isoliquiritigenin (ISL) on VEGF secretion in Human breast cancer cell line MDA-MB-231 Cancer Research
06/04/2012
Abstract 1990: Effects of pomegranate extract on proliferation, apoptosis and mRNA expression in human breast cancer cells Cancer Research
06/04/2012
Abstract 1989: The effect of resveratrol combined with DFMO or DenSpm on MCF-7 breast cancer cells and MCF-10a non-cancerous cells Cancer Research
06/04/2012
Abstract 1988: Increased expression of eukaryotic protein synthesis initiation factor eIF4G by the daidzein metabolite equol may contribute to breast cancer malignancy Cancer Research
06/04/2012
Abstract 1987: Ganoderma lucidum (Reishi) suppresses key protein synthesis initiation molecules in inflammatory breast cancer Cancer Research
06/04/2012
Abstract 1986: GBM cell migration and proliferation is inhibited by crude Rosa canina plant extracts Cancer Research
06/04/2012
Abstract 1985: Omega-3 polyunsaturated fatty acids induce cell cytotoxicity through apoptosis and autophgy in brain cancer in vitro and in vivo Cancer Research
06/04/2012
Abstract 1984: Nature's pharmacy: eburnamonine and its derivative as therapeutics against brain tumors Cancer Research
06/04/2012
Abstract 1983: Thymoquinone induces cell killing in glioblastoma cells through generation of DNA damage and cell cycle arrest Cancer Research
06/04/2012
Abstract 1982: Turmeric oil inhibits hepatocellular carcinoma through abolishing EpCAM expression Cancer Research
06/04/2012
Abstract 1981: Interference of the polyphenolic compound curcumin with expression regulation of target genes of the PLAG1 oncogenic transcription factor Cancer Research
06/04/2012
Abstract 1980: Dihydroartemisinin inhibits ovarian cancer growth and metastasis via targeting PDGFR{alpha} Cancer Research
06/04/2012
Abstract 1979: Sweet wormwood-derived artesunate causes cell cycle arrest in ovarian cancer cell lines Cancer Research
06/04/2012
Abstract 1978: Isorhamnetin modulates PPAR{delta} activation pathway leading to the suppression of proliferation, invasion and induction of apoptosis in gastric cancer Cancer Research
06/04/2012
Abstract 1977: Higher doses of BAMLET may be required to induce cell death in HPV16-infected cancer cells Cancer Research
06/04/2012
Abstract 1976: Monocytic/macrophagic differentiation status of human promyelocytic leukemia cells dictates targeting efficacy of NF-kappaB downstream gene productes Cancer Research
06/04/2012
Abstract 1975: The mitochondrial pathway in baicalein and wogonin-induced apoptosis in human colorectal cancer cells Cancer Research
06/04/2012
Abstract 1974: Growth inhibition and antitumor activity of chikusetsusaponin IVa methyl ester, an oleanane-type triterpenoid from the root of Acyranthes japonica, in HCT 116 human colon cancer cells Cancer Research
06/04/2012
Abstract 1973: Falcarindiol induces colorectal cancer cell death through activation of ER stress Cancer Research
06/04/2012
Abstract 1972: Active targeting, fluorescence imaging, and NIR photothermal therapy of malignant tumors Cancer Research
06/04/2012
Abstract 1970: Liposomal nanoparticle siRNA delivery systems for in vivo silencing of the androgen receptor in human prostate cancer Cancer Research
06/04/2012
Abstract 1969: Silencing {alpha}III-tubulin by RNA interfering nanoparticles in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 1968: Nanoparticle mediated measurement of target-drug binding in cancer cells Cancer Research
06/04/2012
Abstract 1967: Multi-stage silicon vector-delivered tumor antigen and TLR ligands for dendritic cell-based cancer immunotherapy Cancer Research
06/04/2012
Abstract 1966: Plasmonic gold nanostars: A potential agent for molecular imaging and cancer therapy Cancer Research
06/04/2012
Abstract 1965: Evaluating the use of Fe3O4@TiO2 nanoparticles and nanoconjugates with a HPV 18 E2 peptide as a potential therapy for HPV containing cancer cells Cancer Research
06/04/2012
Abstract 1964: Development of a nanovaccine for cancer therapy Cancer Research
06/04/2012
Abstract 1962: Engineering of EGFR-targeted nanoparticles for triple negative breast cancer therapy Cancer Research
06/04/2012
Abstract 1961: Evaluated mechanism of dual targeting using liposomal doxorubicin-modified novel PEG by imaging analysis Cancer Research
06/04/2012
Abstract 1960: Nanosponges as suitable platforms for targeted chemotherapy Cancer Research
06/04/2012
Abstract 1959: Surface modifications and drug-loading affect immunogenicity of targeted nanoparticles Cancer Research
06/04/2012
Abstract 1958: T-oligo mechanism of action and delivery with an alpha-helical peptide Cancer Research
06/04/2012
Abstract 1957: Targeted polymer-based nanoparticles containing camptothecin: Development and function Cancer Research
06/04/2012
Abstract 1956: Folate coated platinum nanoparticles: An effective strategy for targeting cancer therapy Cancer Research
06/04/2012
Abstract 1955: Simultaneous delivery of siRNA and cisplatin by polymer-lipid hybrid nanoparticles sensitizes resistant cancer to chemotherapy Cancer Research
06/04/2012
Abstract 1954: Synthesis and self-assembly of highly PEGylated dendron-coils: A potential nanocarrier platform Cancer Research
06/04/2012
Abstract 1953: Co-delivery of doxorubicin and siRNA using octreotide-conjugated gold nanorods for targeted neuroendocrine cancer therapy Cancer Research
06/04/2012
Abstract 1952: Targeting the CCL2/CCR2 chemokine pathway in breast tumors through intratumoral delivery of calcium cross linked TAT peptide: siRNA complexes Cancer Research
06/04/2012
Abstract 1951: Targeting cancer by a chimeric nanoparticle formulation of Cisplatin and PI828, a PI3 kinase inhibitor Cancer Research
06/04/2012
Abstract 2279: Akt inhibitor SC-66 leads to inhibition of mTOR pathway in cervical cancer cell line C33A. Cancer Research
06/04/2012
Abstract 2278: Smac mimetic primes FADD- or caspase-8-deficient leukemia cells for TNF{alpha}-induced necroptosis and overcomes apoptosis resistance Cancer Research
06/04/2012
Abstract 2277: Autophagy-associated necroptosis contributes to cancer cell cytotoxicity induced by the chalcone compound SBC2 Cancer Research
06/04/2012
Abstract 2276: Coordinate autophagy and PI3K/Akt/mTOR pathway inhibition enhances cell death in melanoma Cancer Research
06/04/2012
Abstract 2275: A novel heat shock protein 90 inhibitor, NVP-AUY922, enhances the antitumor effect of imatinib via autophagy on imatinib-resistant CML cells Cancer Research
06/04/2012
Abstract 2274: Docosahexaenoic acid-induced cell death may be related to inhibition of mTOR through AMPK activation and PI3K/Akt inhibition in human non-small cell lung cancer cells Cancer Research
06/04/2012
Abstract 2273: Autophagic cell death induced by curcumin is mediated by p38/Beclin 1 to crosstalk with apoptotic cell death in DU145 cells Cancer Research
06/04/2012
Abstract 2272: Heme oxygenase-1 regulates apoptosis and autophagy for the survival of renal cancer cells Cancer Research
06/04/2012
Abstract 2271: Autophagy induction by low dose cisplatin: The role of p53 in autophagy Cancer Research
06/04/2012
Abstract 2270: Non-invasive radiofrequency increases the anticancer effect of gemcitabine in treating pancreatic cancer via autophagy Cancer Research
06/04/2012
Abstract 2268: Suicidal tendencies: The promotion of cell death by a prolactin antagonist through autophagy in ovarian cancer Cancer Research
06/04/2012
Abstract 2267: Inhibition of autophagy in hypoxic HT29 cells reverses hypoxia-induced resistance to oxaliplatin Cancer Research
06/04/2012
Abstract 2266: Beclin-1 regulation of autophagy in endocrine resistant breast cancer Cancer Research
06/04/2012
Abstract 2265: Embelin induces autophagy in ovarian cancer cells Cancer Research
06/04/2012
Abstract 2264: Autophagy inhibition sensitizes the growth inhibitory effects of propolin C but not propolin G on human lung adenocarcinoma A549 cells Cancer Research
06/04/2012
Abstract 2263: Autophagy protects against Src tyrosine kinase inhibitor treatment in non-small cell lung cancer cells via a novel miR-106a/ULK1 pathway Cancer Research
06/04/2012
Abstract 2262: Contribution of autophagy in anticancer immune response induced by chemotherapy Cancer Research
06/04/2012
Abstract 2261: Heat-shock and autophagy in cancer: Novel role for DGK iota Cancer Research
06/04/2012
Abstract 2260: Novel molecular therapy targeting Mcl-1 and modulating autophagy in castration-resistant prostate cancer Cancer Research
06/04/2012
Abstract 2259: Oncolytic attenuated measles virus exploits autophagy for its replication and spreads by suppressing Rig-1 like receptors (RLRs) in non-small cell lung cancer cells Cancer Research
06/04/2012
Abstract 2258: Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells Cancer Research
06/04/2012
Abstract 2257: Role of Survivin and small heat shock proteins in the chemoresistance of retinoblastoma Cancer Research
06/04/2012
Abstract 2255: Inhibition of 5-lipoxygenase interrupts c-Myc oncogenic signaling Cancer Research
06/04/2012
Abstract 2254: FIP200 regulation by hypoxia in brain endothelial cells Cancer Research
06/04/2012
Abstract 2253: New targets of mTORC1 pathway in ER-positive cells Cancer Research
06/04/2012
Abstract 2251: Loss of epithelial PTEN affects gastric homeostasis and leads to spasmolytic polypeptide-expressing metaplasia in the mouse Cancer Research
06/04/2012
Abstract 2250: Combination of PARP inhibitor, Olaparib with pathway-targeted drug, vandetanib (Caprelsa™) in TNBC: A proof of principle study to determine the role of PI3K-AKT-mTOR or RAS-MAPK pathways in targeted drug-response Cancer Research
06/04/2012
Abstract 2249: Mutations to the GSK3{beta} regulatory region of CTNNB1 increase TCF transcription activity and are resistant to degradation by GSK3{beta} Cancer Research
06/04/2012
Abstract 2248: Both rpS6 and 4EBP1 are required for the carcinogenesis induced by coactivation of AKT and Ras Cancer Research
06/04/2012
Abstract 2247: Torin2 targets mTOR activity and induces apoptosis in DLBCL cells Cancer Research
06/04/2012
Abstract 2246: Combined grape polyphenols regulate mammalian target of rapamycin (mTOR) signaling via a dual mechanism of Akt inhibition and AMPK activation Cancer Research
06/04/2012
Abstract 2245: The role of STAT3{alpha} in Pten-dependent hematopoietic malignancy Cancer Research
06/04/2012
Abstract 2244: AKT activation by Pdcd4 knockdown upregulates cyclin D1 expression and promotes cell proliferation Cancer Research
06/04/2012
Abstract 2243: Targeting the MUC1-C oncoprotein synergistically enhances cytotoxicity of breast carcinoma cells in combination with PI3K inhibitors Cancer Research
06/04/2012
Abstract 2242: The MAPK and PI3K signaling pathways in breast cancer: Crosstalk mechanisms and the effect on cell proliferation Cancer Research
06/04/2012
Abstract 2241: Differential regulation of Gli1 transcriptional activity by MAPK and PI3K pathways in neuroblastoma Cancer Research
06/04/2012
Abstract 2240: Pre-clinical potency of INK128, a highly potent TORC1/2 kinase inhibitor in the HER2 amplified breast cancer model Cancer Research
06/04/2012
Abstract 2239: The effect combining the KIT inhibitor Imatinib with the PI3K inhibitor BKM120 or the dual PI3K/mTOR inhibitor BEZ235 on the proliferation of gastrointestinal stromal tumor cell lines Cancer Research
06/04/2012
Abstract 2238: Role of phosphoinositide-dependent protein kinase-1 (PDK1) in leukemogenesis of acute leukemia Cancer Research
06/04/2012
Abstract 2237: Analysis of the PI3K/Akt signaling pathway in neuroblastoma shows stage dependent expression of PI3K isoforms Cancer Research
06/04/2012
Abstract 2236: Perifosine induces in vitro and in vivo antitumor activity in gastric cancer cells Cancer Research
06/04/2012
Abstract 2235: GAL-1 function as an alternative PI3K pathway activator depends on PTEN and EGFR status in CHO cells Cancer Research
06/04/2012
Abstract 2234: Activation of PI3K pathway by P-Rex2 is inhibited by GNMT Cancer Research
06/04/2012
Abstract 2233: IKBKE activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 to sustain malignant transformation Cancer Research
06/04/2012
Abstract 2232: Overexpression of the mu opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth and metastasis Cancer Research
06/04/2012
Abstract 2228: mTORC2 is a promising therapeutic target in epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 2227: P110 {alpha}-specific inhibitor is more suitable in PIK3CA mutated breast cancer model but ineffective in PTEN loss of function breast cancer model Cancer Research
06/04/2012
Abstract 2226: Mechanisms for cross-talk between Notch1 and AKT signaling in T-cell acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 2224: Targeted PI3K/mTOR inhibition impairs tumor cell motility and bone metastatic outgrowth via modulation of p27 Cancer Research
06/04/2012
Abstract 2223: Epigenetic silencing of ribosomal RNA genes by Mybbp1a Cancer Research
06/04/2012
Abstract 2221: Dimerization and DNA binding specificities unravelled by the structure of MITF Cancer Research
06/04/2012
Abstract 2220: p53 dimers associate with a head-to-head element to repress cyclin B transcription Cancer Research
06/04/2012
Abstract 2219: Mechanism of trancriptional repression by EWS/FLI in Ewing's sarcoma Cancer Research
06/04/2012
Abstract 2218: Radiation-induced hypomethylation triggers urokinase plasminogen activator (uPA) transcription in meningioma cells Cancer Research
06/04/2012
Abstract 2217: Stress-induced NQO1 controls stability of C/EBP{alpha} against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer Cancer Research
06/04/2012
Abstract 2216: SUMOylated CPAP contributes to NF-kB activation in cancer cells Cancer Research
06/04/2012
Abstract 2214: COUP-TFII suppresses NF{kappa}B activation in endocrine-resistant breast cancer cells Cancer Research
06/04/2012
Abstract 2213: Aberrant expression of TRIM24 in breast cancer progression is linked to loss of repressive histone marks at the promoter Cancer Research
06/04/2012
Abstract 2212: C-terminus-truncated hepatitis B virus X protein enhances cell invasiveness in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 2211: Accessible chromatin structure permits factors Sp1 and Sp3 to regulate human TGFBI gene expression Cancer Research
06/04/2012
Abstract 2210: Global levels of H3K27me3 track with differentiation in vivo and are deregulated by MYC in prostate cancer Cancer Research
06/04/2012
Abstract 2209: Cellular characterization of chromatin state via high throughput ChIP assay Cancer Research
06/04/2012
Abstract 2207: SUMOylation of EAPII/TTRAP/TDP2 modulates its function Cancer Research
06/04/2012
Abstract 2206: Molecular interaction of HIF-1{alpha} and the androgen receptor in prostate cancer Cancer Research
06/04/2012
Abstract 2205: The EVI1 human protein regulates its own transcription. Role of the different isoforms Cancer Research
06/04/2012
Abstract 2203: AP-1 activation and a functional SNP242 regulates the LY-6K gene expression in human breast cancer cells Cancer Research
06/04/2012
Abstract 2202: HMG box-containing protein 1 (HBP1) is a direct target of transcription factor FOXO1 in invasive oral cancer Cancer Research
06/04/2012
Abstract 2201: A novel androgen receptor regulatory loop: Posttranscriptional androgen receptor regulation through Midline 1 ribonuclear protein complex Cancer Research
06/04/2012
Abstract 2200: Identification of GLI1 binding partners that regulate transactivation or cell transformation Cancer Research
06/04/2012
Abstract 2199: Death Associated Protein Kinase 2 (DAPK2) is a novel transcriptional target of PML-RARA and PU.1 (SPI1) during neutrophil differentiation of acute promyelocytic leukemia (APL) cells Cancer Research
06/04/2012
Abstract 2198: A functional ETS/E2F module in cancers expressing ETS fusion genes Cancer Research
06/04/2012
Abstract 2197: Fliz-1 regulation of GATA-3 expression in mammary tumor cells Cancer Research
06/04/2012
Abstract 2196: Upregulation of survivin during immortalization is linked to repression of p16INK4a and confers resistance to oxidative stress Cancer Research
06/04/2012
Abstract 2195: Smurf2 is a novel tumor suppressor gene that governs chromatin structure and genome integrity through RNF20 Cancer Research
06/04/2012
Abstract 2194: KLF4 overexpression and apigenin treatment inhibited cell migration and induced apoptosis in human malignant neuroblastoma SK-N-DZ and IMR32 cells Cancer Research
06/04/2012
Abstract 2193: WT1 mediated regulation of growth control genes in leukemia Cancer Research
06/04/2012
Abstract 2192: Genomic amplification and drug-resistance roles of the KDM5A histone demethylase gene in breast cancer Cancer Research
06/04/2012
Abstract 2191: Mutational analysis of DNMT3A gene in acute leukemias and common solid cancers Cancer Research
06/04/2012
Abstract 2190: Epigenetic mechanisms of transformation for the NSD3 oncogene in human breast cancer cells with the 8p11-p12 amplicon Cancer Research
06/04/2012
Abstract 2188: The ubiquitin-specific protease USP2a targets cyclin A1: A potential role in bladder cancer Cancer Research
06/04/2012
Abstract 2187: Plk2 loss and mTOR signaling in advanced colorectal cancer Cancer Research
06/04/2012
Abstract 2185: BRD4 is a novel therapeutic target in melanoma Cancer Research
06/04/2012
Abstract 2183: Determining the functional roles of the specific isoforms of ARID3B from cellular localizations Cancer Research
06/04/2012
Abstract 2182: Epigenetic regulation and growth suppression by NDN, an imprinted tumor suppressor gene whose expression is decreased in epithelial ovarian cancers Cancer Research
06/04/2012
Abstract 2181: Characterization of PHF11, a candidate tumor suppressor gene, in esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2180: Identification of nuclear transcription factor Y (NF-Y) as a novel key transcriptional regulator of the tumor-suppressor gene DAPK1 Cancer Research
06/04/2012
Abstract 2179: Histopathologic and genetic features of lung adenocarcinomas with loss of chromatin remodeling factors, BRG-1 and BRM Cancer Research
06/04/2012
Abstract 2178: ARID1B, a member of the human SWI/SNF chromatin remodeling complex, is a novel tumor suppressor gene in pancreatic cancer Cancer Research
06/04/2012
Abstract 2177: Tumor suppressor effects of ETS2 transcriptional factor in human non-small cell lung cancer Cancer Research
06/04/2012
Abstract 2176: Deletion of 3p14 is linked to ERG-fusion positive prostate cancers and harbors the FOXP1 tumor suppressor gene Cancer Research
06/04/2012
Abstract 2174: MLL3 act as a tumor suppressor gene in pancreatic cancer Cancer Research
06/04/2012
Abstract 2173: Heterozygosity for Mtap accelerates lymphomagenesis in Emu-Myc and Pten +/- mice Cancer Research
06/04/2012
Abstract 2170: The SWI/SNF nucleosome-remodeling gene PBRM1 - Another tumor suppressor gene in renal cell carcinomas Cancer Research
06/04/2012
Abstract 2168: Per2 (PERIOD 2) mediates low-dose radiation-induced adaptive response in human mammary epithelial cells Cancer Research
06/04/2012
Abstract 2167: The tumor suppressor CDC73/parafibromin is required for the maintenance of histone 2B monoubiquitination both in vitro and in vivo Cancer Research
06/04/2012
Abstract 2166: In silico identification and biological evaluation of potent small molecule inhibitors targeting GAB1 pleckstrin homology domain Cancer Research
06/04/2012
Abstract 2165: Sprouty loss leads to aberrant regulation of receptor tyrosine kinase signaling pathways and accelerates mammary tumorigenesis Cancer Research
06/04/2012
Abstract 2164: S100B affects MAPK signaling in malignant melanoma via a direct interaction with RSK Cancer Research
06/04/2012
Abstract 2163: RSK signaling in HER2-positive breast cancer cells Cancer Research
06/04/2012
Abstract 2162: EGFR-induced interaction of GSTP1 with the SH2-domain of Grb2 enhances Ras downstream activation in human glioma cells Cancer Research
06/04/2012
Abstract 2159: Targeting GRB7/ERK/FOXM1 signaling cascade is a promising therapeutic approach in ovarian cancer Cancer Research
06/04/2012
Abstract 2158: RAF signaling and SHOC2 mediate mutant NRAS acquired resistance to RAF inhibitors in melanoma Cancer Research
06/04/2012
Abstract 2157: A novel role for Gi{alpha} proteins in differentially regulating activation of RTK-mediated signaling Cancer Research
06/04/2012
Abstract 2156: Preclinical combinations of vemurafenib, a selective BRAF inhibitor, with other targeted therapies in BRAFV600E colorectal cancer models Cancer Research
06/04/2012
Abstract 2154: CDCP1 links RAS and Src signaling pathways as a common effector for the promotion of tumor metastasis Cancer Research
06/04/2012
Abstract 2153: Active PAK6 induces aneuploidy in breast cancer cells Cancer Research
06/04/2012
Abstract 2152: p38{alpha} MAPK regulates signal transduction between estrogen receptor (ER) and its antagonist by switching ER signaling from the classical to the non-classical pathway Cancer Research
06/04/2012
Abstract 2150: The role of SHP2 in HER2+ breast cancer Cancer Research
06/04/2012
Abstract 2149: Cooperation of Notch and RAS/MAPK pathway leads to poor outcome in breast cancer patients Cancer Research
06/04/2012
Abstract 2148: Exploitation of androgen receptor splice variant signaling by guanine nucleotide exchange factor Vav3 in castration resistant prostate cancer Cancer Research
06/04/2012
Abstract 2147: The RRas2/TC21 GTPase is essential for breast tumorigenesis and lung metastasis Cancer Research
06/04/2012
Abstract 2146: The Rho GTPase RhoE is a p53-regulated candidate tumor suppressor Cancer Research
06/04/2012
Abstract 2145: Coupling S100A4 to Rhotekin alters Rho signaling output in breast cancer cells Cancer Research
06/04/2012
Abstract 2144: RasGRP1 induces autophagy in primary human epidermal keratinocytes resembling fail-safe mechanisms triggered by oncogenic Ras Cancer Research
06/04/2012
Abstract 2141: cAMP/PKA signaling enhances activity of Deleted in Liver Cancer 1 (DLC1) tumor suppressor in suppressing liver cancer tumorigenesis Cancer Research
06/04/2012
Abstract 2138: Tumorigenic and migratory potential of Ral GTPases in non-small cell lung cancers Cancer Research
06/04/2012
Abstract 2136: Nuclear trafficking of Tie2 is associated with radioresistance of gliomas Cancer Research
06/04/2012
Abstract 2135: Proline, glutamic acid, leucine rich protein 1 (PELP1) is essential for optimal p53-mediated DNA damage response Cancer Research
06/04/2012
Abstract 2133: MCPH1 interacts with the anaphase-promoting complex subunit Cdc27 Cancer Research
06/04/2012
Abstract 2132: Characterization of galectin 3 as a novel BARD1 interaction partner Cancer Research
06/04/2012
Abstract 2131: Plk1 decreases DNA double strand break (DSB) formation during replication- stalling genotoxic stress Cancer Research
06/04/2012
Abstract 2130: DNA repair biochip-based screening to identify Glycosylase/AP endonuclease inhibitors: from the concept to the identification of effective molecules Cancer Research
06/04/2012
Abstract 2128: A new protein complex containing the Fanconi protein FANCM and Rif1 Cancer Research
06/04/2012
Abstract 2125: A new method for assessing fidelity of DSB repair shows involvement of different DNA repair mechanisms at specific sites in human genome Cancer Research
06/04/2012
Abstract 2124: Non-homologues end joining mediates fatty acid synthase(FASN)-associated resistance to DNA-damaging chemotherapeutics Cancer Research
06/04/2012
Abstract 2122: Chronic inflammatory levels of nitric oxide/reactive nitrogen species down-regulate BRCA1 protein expression and decrease homologous recombination Cancer Research
06/04/2012
Abstract 2121: Nonerythroid alpha spectrin prevents telomere fragility after DNA interstrand crosslink damage Cancer Research
06/04/2012
Abstract 2120: Hepatitis B virus X protein interacts with PARP1 that inhibits DNA repair Cancer Research
06/04/2012
Abstract 2119: DDB2 and XPC influence ATR and ATM recruitment and regulate DNA damage response upon UV irradiation Cancer Research
06/04/2012
Abstract 2118: Particulate chromate induces persistent DNA double strand breaks resulting in disruption of homologous recombination repair in human lung cells Cancer Research
06/04/2012
Abstract 2116: CHEK2 (Chk2) endogenous activation is associated with p53 deficiency and downregulation of BRCA2 and Fanconi Anemia pathway gene members in the National Cancer Institute Anticancer Tumor Cell Line Panel (NCI-60) Cancer Research
06/04/2012
Abstract 2114: Trypanosoma brucei: A model to evaluate joint contribution of BRCA2 and PARP in DNA damage repair Cancer Research
06/04/2012
Abstract 2112: CA-microsatellite instability as a factor of branch migration impeding in Holliday junctions Cancer Research
06/04/2012
Abstract 2111A: Molecular genetics of non-alcoholic fatty liver disease Cancer Research
06/04/2012
Abstract 2111: Characterization of current and novel biomarkers of bladder cancer Cancer Research
06/04/2012
Abstract 2110: An attempt to replicate the results of genome-wide association studies on lung cancer susceptibility loci in a Korean population Cancer Research
06/04/2012
Abstract 2109: PIK3CA mutations in hepatocellular carcinoma in Korea Cancer Research
06/04/2012
Abstract 2108: Prevalence of mutations in MSH6, PMS1 and PMS2 gene in Brazilian families with Lynch syndrome Cancer Research
06/04/2012
Abstract 2107: Clonal patterns of chromosomal aberrations in cervical cancers and precursor lesions Cancer Research
06/04/2012
Abstract 2106: Long non-coding RNA signatures for melanoma detection in humans Cancer Research
06/04/2012
Abstract 3500: T cells redirected against HER2 for the adoptive immunotherapy for HER2-positive osteosarcoma Cancer Research
06/04/2012
Abstract 3499: CD56 targeted chimeric antigen receptors for immunotherapy of multiple myeloma Cancer Research
06/04/2012
Abstract 3498: Synergistic effects of sinomenine combined with low dose cyclosporine A on acute graft-versus-host disease in a murine model Cancer Research
06/04/2012
Abstract 3497: A novel pathway involving Tcf-driven Bcl2 under regulation of Bmi-1 stem cell factor: Role in chemoresistance Cancer Research
06/04/2012
Abstract 3496: Self-renewal as a therapeutic target in human colorectal cancer Cancer Research
06/04/2012
Abstract 3495: The novel phospholipid ether analog CLR1404 decreases glioblastoma stem cell proliferation, suppresses GBM growth, and improves survival Cancer Research
06/04/2012
Abstract 3494: Liver X receptor activation represents a novel strategy to block Hedgehog signaling in pancreatic adenocarcinoma and enhance the antitumor effect of gemcitabine Cancer Research
06/04/2012
Abstract 3493: Soluble ALK4 extracellular domain antagonizes the cancer/stem cell phenotype caused by Nodal and Cripto signaling in mammary epithelia Cancer Research
06/04/2012
Abstract 3492: {gamma}-secretase inhibitor PF-03084014 diminishes the tumor-initiating cells and demonstrates synergy with docetaxel in breast cancer xenograft models Cancer Research
06/04/2012
Abstract 3491: Development of a new approach to kill non-small cell lung cancer cells with resistance to standard chemotherapy using parthenolide analogues Cancer Research
06/04/2012
Abstract 3490: Targeting E3 ligases in liver cancer stem cells with disruption of TGF-{beta} signaling Cancer Research
06/04/2012
Abstract 3489: Genistein inhibits highly proliferative hematopoietic stem cells Cancer Research
06/04/2012
Abstract 3488: Targeting ligands and nanotherapeutics against acute myeloid leukemia stem cell Cancer Research
06/04/2012
Abstract 3487: Distant delivery of glioma-restricted oncolytic adenovirus loaded into a neural stem cell-based carrier prolongs the survival of animals with human glioblastoma Cancer Research
06/04/2012
Abstract 3486: Novel cell models of ovarian cancer for target discovery and validation obtained through stem cell culturing technology Cancer Research
06/04/2012
Abstract 3485: Inhibition of Notch signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells Cancer Research
06/04/2012
Abstract 3484: Distinct cancer cell with stem cell like properties contribute to doxorubicin and paclitaxel resistance Cancer Research
06/04/2012
Abstract 3483: Inhibition of Monocarboxylate Transporter 4 (MCT4) targets stem-like cells in glioblastoma Cancer Research
06/04/2012
Abstract 3482: Validation of novel therapeutic targets for T-cell non-Hodgkin lymphoma Cancer Research
06/04/2012
Abstract 3481: Dietary acetate supplementation as a means of inducing glioma stem cell growth arrest Cancer Research
06/04/2012
Abstract 3479: Targeting FoxM1 selectively depletes hepatic cancer stem cells Cancer Research
06/04/2012
Abstract 3478: CD44+CD24low+ progenitors in ER negative breast cancer have higher Notch1 activation, self-renewal, and chemo resistance and generate CD44+CD24neg cells and tumors that metastasize Cancer Research
06/04/2012
Abstract 3477: Tamoxifen leads to an increase in tumor cells with self-renewing capacity in a mouse model of estrogen dependent breast cancer Cancer Research
06/04/2012
Abstract 3476: Hyaluronan-mediated motility receptor as a novel target for inhibiting glioblastoma stem cells Cancer Research
06/04/2012
Abstract 3475: Inhibition of the TGF{beta} pathway inhibits chemotherapy-induced enrichment of breast cancer stem cells in triple-negative breast cancer Cancer Research
06/04/2012
Abstract 3474: Ovarian cancer tumor initiating cells persist after paclitaxel and carboplatinum treatment in vivo Cancer Research
06/04/2012
Abstract 3473: Beta catenin inhibitor ICG-001 attenuates proliferation of hepatic tumor initiating cells in Pten deficient models Cancer Research
06/04/2012
Abstract 3472: Molecular mechanisms of growth inhibition of human brain tumor stem cells and glioblastoma LN18 and U138MG cells by combination of curcumin and paclitaxel Cancer Research
06/04/2012
Abstract 3471: Paclitaxel selects and enriches for CD44+/MyD88+ ovarian cancer stem cells Cancer Research
06/04/2012
Abstract 3468: Endoscopic diagnosis and treatment of esophageal tumor using a novel DDS-type photoactivatable agent Cancer Research
06/04/2012
Abstract 3466: Mitochondrial targeting photosensitizer-lipophilic cation conjugates for photodynamic therapy Cancer Research
06/04/2012
Abstract 3465: The effect of ephrin-A1 on the resistance of photodynamic therapy in esophageal cancer cells Cancer Research
06/04/2012
Abstract 3464: Aminolevulinic acid-mediated photodynamic therapy induces cell death in human osteosarcoma cells Cancer Research
06/04/2012
Abstract 3463: The role of Atg13 in response to radiotherapy in cervical cancer cells Cancer Research
06/04/2012
Abstract 3461: C-kit inhibitors and radiation: A promising combination in NSCLC Cancer Research
06/04/2012
Abstract 3460: Inhibition of c-met radio-sensitizes in breast cancer brain metastatic cancer Cancer Research
06/04/2012
Abstract 3459: Radioresistence mechanism of prostate cancer stem cells Cancer Research
06/04/2012
Abstract 3458: Wnt activation is implicated in glioblastoma radioresistance Cancer Research
06/04/2012
Abstract 3457: Galectin-1 suppression enhances combined anti-EGFR and radiation-therapy of NSCLC Cancer Research
06/04/2012
Abstract 3455: p53 status determines the radio-sensitizing effect of an Akt kinase inhibitor in malignant gliomas Cancer Research
06/04/2012
Abstract 3454: Establishing role of KRAS mutation on NSCLC radio-sensitivity Cancer Research
06/04/2012
Abstract 3453: SPARC overexpression inhibits cell proliferation in neuroblastoma and is partly mediated by tumor suppressor protein PTEN and AKT Cancer Research
06/04/2012
Abstract 3452: The role of CX3CR1 in resistance of ovarian carcinoma cells to radiation therapy Cancer Research
06/04/2012
Abstract 3451: Lack of CD47 in the tumor microenvironment enhances anti-tumor adaptive immune responses when combined with ionizing radiation Cancer Research
06/04/2012
Abstract 3450: Functional characterization of a DNA damage response network in glioblastoma associated with long-term patient survival Cancer Research
06/04/2012
Abstract 3449: Impact of BRCA2 mutation in primary human triple negative breast cancer xenografts on the responses to ionizing radiation and in vivo tumor growth after treatment Cancer Research
06/04/2012
Abstract 3448: Association of reactive oxygen species (ROS) levels and radiosensitivity by knockdown of ZEB1 in NSCLC Cancer Research
06/04/2012
Abstract 3447: Tetrac (tetraiidothyroacetic acid) decreases in vitro x-ray survival of a human medullary thyroid cancer cell line under oxic and hypoxic conditions Cancer Research
06/04/2012
Abstract 3446: Stat3 is a potential molecular target for chemoradiosensitization of colorectal cancer cells Cancer Research
06/04/2012
Abstract 2304: MicroRNA-7 functions as antimetastic microRNA in gastric cancer by targeting insulin-like growth factor 1 receptor Cancer Research
06/04/2012
Abstract 2303: MicroRNA-23b is a tumor suppressor and a useful prognostic biomarker in prostate cancer Cancer Research
06/04/2012
Abstract 2302: Epigenetic activation of miR-200a targets the Nrf2-dependent chemoprevention pathway in breast cancer Cancer Research
06/04/2012
Abstract 2301: Epigenetic regulation of microRNA-200a and 141 by proto-oncogene PELP1: Role in breast cancer progression and metastasis Cancer Research
06/04/2012
Abstract 2300: MicroRNA-101 (miR-101) posttranscriptionally regulates the expression of EP4 receptor in colon cancers Cancer Research
06/04/2012
Abstract 2299: Genistein suppresses prostate cancer growth through inhibition of oncogenic miR-151 Cancer Research
06/04/2012
Abstract 2297: MicroRNAs inhibit breast canncer metastasis via targeting CXC chemokine receptor 4 Cancer Research
06/04/2012
Abstract 2296: Aldose reductase inhibition prevents human colon cancer cells growth by miR-21 and FOXO3a-mediated regulation of PTEN Cancer Research
06/04/2012
Abstract 2295: miR-342 modulates ID4 expression in breast cancer Cancer Research
06/04/2012
Abstract 2294: Let-7a inhibits neuroblastoma cell proliferation by directly targeting the MYCN oncogene Cancer Research
06/04/2012
Abstract 2293: MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. Cancer Research
06/04/2012
Abstract 2292: Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells Cancer Research
06/04/2012
Abstract 2291: Oncogenic hsa-miR-1323 down-regulates MYCN/ALK and reveals PAG1 as a novel tumor suppressor for neuroblastoma Cancer Research
06/04/2012
Abstract 2289: miR-497 targets cell cycle regulator WEE1 in neuroblastoma Cancer Research
06/04/2012
Abstract 2288: Genetic and epigenetic inactivation of miR-31 in EBV-associated nasopharyngeal carcinoma Cancer Research
06/04/2012
Abstract 2287: Inhibition of microRNA-32 leads to decreased expression of the survival-enhancing scaffold protein hKSR2 in human myeloid leukemia cells treated with vitamin D derivatives Cancer Research
06/04/2012
Abstract 2286: p53-miR-dependent post-transcriptional circuits: mechanisms, targets and inter-individual variation Cancer Research
06/04/2012
Abstract 2284: MIR-200 family as EMT related microRNA in renal cell carcinoma Cancer Research
06/04/2012
Abstract 2282: Targeting oncogenic NDRG4: A promising strategy for meningioma treatment Cancer Research
06/04/2012
Abstract 2281: Signaling from lysosomes to mitochondria sensitizes head and neck cancer cells to photodynamic treatment: Role of mitoferrin 2 Cancer Research
06/04/2012
Abstract 2280: Role of MAP1LC3 in 15d-PGJ2 induced non-apoptotic and non-autophagic cell death in therapy-resistant triple negative breast tumors Cancer Research
06/04/2012
Abstract 1950: LHRH Peptide decorated cross-linked micelles for the targeted drug delivery to breast cancer Cancer Research
06/04/2012
Abstract 1949: Receptor mediated delivery of therapeutic Fe3O4 core TiO2 shell nanoparticles Cancer Research
06/04/2012
Abstract 1947: Self-reporting dendritic nanoparticles (nanodendrons) for drug delivery targeted to the tumor microenvironment and with reduced neurotoxicity Cancer Research
06/04/2012
Abstract 1946: Silencing of EVI1 with siRNA inhibits the growth of ovarian tumor cells Cancer Research
06/04/2012
Abstract 1944: A novel vasoactive intestinal peptide-grafted curcumin nanomedicine for targeting breast cancer stem cells Cancer Research
06/04/2012
Abstract 1943: On-demand reversible boronate-catechol crosslinked nanocarriers for cancer therapy Cancer Research
06/04/2012
Abstract 1942: Activity of lenalidomide in vitro and in vivo models of bortezomib-resistant mantle cell lymphoma involving the modulation of c-myc/p27 axis Cancer Research
06/04/2012
Abstract 1941: Development of novel NSAID conjugated molecules for lung cancer therapy Cancer Research
06/04/2012
Abstract 1940: Anti-tumor action of adenosine A3 receptor in prostate cancer involves suppression of micro RNA-21 Cancer Research
06/04/2012
Abstract 1938: Angiotensin-(1-7), a peptide hormone with therapeutic potential for the treatment of glioblastomas Cancer Research
06/04/2012
Abstract 1937: APE/Ref-1, a drugable target for the therapy of human melanoma Cancer Research
06/04/2012
Abstract 1934: Characterization of the anti-proliferative effect of 6-(3-aminopropyl)-9-methoxy-3-nitro-5H-indeno[1,2-c]isoquinoline-5,11(6H)-dione in cultured PC-3 cells Cancer Research
06/04/2012
Abstract 1933: Ellagic acid induces apoptosis and cell cycle arrest in HeLa cells and inhibits HPV oncogene expression Cancer Research
06/04/2012
Abstract 1931: A potential antitumor herb medicine, Corilagin, inhibits ovarian cancer cell growth by blockage of TGF-{beta}/AKT/ERK signaling pathways Cancer Research
06/04/2012
Abstract 1927: Mechanistic characterization of SC144 in colon cancer Cancer Research
06/04/2012
Abstract 1926: Antitumor and antiangiogenic effects of OTX-008, a novel calyx[4]arene, are mediated by galectin-1 inhibition in human tumor xenograft models Cancer Research
06/04/2012
Abstract 1925: Trifluoromethylated artemisinin dimers demonstrate a potent anti-cancer activity in vitro and in vivo Cancer Research
06/04/2012
Abstract 1924: The aurora kinase inhibitor CYC3 synergizes with low concentrations of paclitaxel in pancreatic cancer cells in vitro Cancer Research
06/04/2012
Abstract 1923: The mTOR kinase inhibitor, CC214, preferentially blocks the growth of EGFRvIII-activated glioblastomas Cancer Research
06/04/2012
Abstract 1922: 2-Aminothiazoles as potent and selective PI3Kalpha inhibitors: Discovery of NVP-BYL719 and structural basis for the isoform selectivity Cancer Research
06/04/2012
Abstract 1921: A novel FAK kinase inhibitor (PF-4554878) decreases growth and induces apoptosis in pancreatic neuroendocrine tumor cells Cancer Research
06/04/2012
Abstract 1920: Small molecule inhibitor of polo-like kinase 1 (Plk1) causes significant melanoma growth delay and regression in vivo Cancer Research
06/04/2012
Abstract 1918: Anti-metastasis effect of EW-7197, a novel ALK5 inhibitor in both breast cancer cells in vitro and mouse model in vivo Cancer Research
06/04/2012
Abstract 1917: Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of primary lung explant models Cancer Research
06/04/2012
Abstract 1915: Novel sorafenib derivatives (SC-40, SC-43 and SC-60) show better anti-tumor effects than sorafenib in hepatocellular carcinoma through SHP-1/STAT3-mediated signaling pathway Cancer Research
06/04/2012
Abstract 1913: Epithelial mesenchymal transition: A mechanism of resistance to VEGF pathway inhibition in genitourinary cancers Cancer Research
06/04/2012
Abstract 1912: Jab1/Csn5 as a novel driver for therapeutic resistance in HER2-positive breast cancer Cancer Research
06/04/2012
Abstract 1911: A common BIM polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer Cancer Research
06/04/2012
Abstract 1909: Cytoprotective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells Cancer Research
06/04/2012
Abstract 1908: MDR1 gene overexpression confers resistance to C-MET inhibitor in multidrug resistant cancer cell line Cancer Research
06/04/2012
Abstract 1907: Heat shock protein 90 inhibition overcomes hepatocyte growth factor-triggering resistance to EGFR tyrosine kinase inhibitors in EGFR mutant lung cancer by decreasing client protein expression and angiogenesis Cancer Research
06/04/2012
Abstract 1906: Mechanisms of resistance to EGFR tyrosine kinase inhibitors involving HER-family ligands and receptors Cancer Research
06/04/2012
Abstract 1904: Transforming growth factor-beta mediated epithelial to mesenchymal transition contributes to in vivo resistance to sorafenib in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 1903: In vitro and in vivo characterization of sunitinib resistance in renal cancer models Cancer Research
06/04/2012
Abstract 1902: Sorafenib overcome irinotecan resistance in colorectal cancer Cancer Research
06/04/2012
Abstract 1899: Endocytosis of EGFR and resistance to gefitinib in NSCLC cells with wild-type EGFR Cancer Research
06/04/2012
Abstract 1898: Potential molecular mechanisms of intrinsic resistance to EGFR-targeting monoclonal antibodies in HNSCC Cancer Research
06/04/2012
Abstract 1897: RAS signaling pathway gene mutations and acquired resistance to EGFR tyrosine-kinase inhibitors in EGFR mutant lung cancer Cancer Research
06/04/2012
Abstract 1895: The role of autophagy and Atg3 in erlotinib-resistant lung cancer and synergistic cell death with combination of erlotinib and cisplatin Cancer Research
06/04/2012
Abstract 1894: Antitumor effects of everolimus, sorafenib, and axitinib in human renal cells carcinoma xenografts resistant to first line treatment by sunitinib Cancer Research
06/04/2012
Abstract 1893: Activating NRAS mutations are associated with FLT3-independent resistance to the clinically active FLT3 inhibitor AC220 in vitro Cancer Research
06/04/2012
Abstract 1892: Identification of differentially methylated genes associated with cetuximab and erlotinib resistance Cancer Research
06/04/2012
Abstract 1891: NF-{kappa}B signaling plays a certain role in apoptosis resistance in 3D-cultured EGFR-mutant lung adenocarcinoma cells Cancer Research
06/04/2012
Abstract 1890: Novel targets mediating resistance to EGFR/c-Met tyrosine kinase inhibitors in NSCLC Cancer Research
06/04/2012
Abstract 1889: Smad4 inactivation correlates with EMT and cetuximab resistance in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 1888: MM-111, a bispecific HER2 and HER3 antibody, inhibits trastuzumab-resistant tumor cell growth Cancer Research
06/04/2012
Abstract 1887: Targeting oncoprotein stability overcomes lapatinib-resistance due to ERBB2 kinase domain mutations Cancer Research
06/04/2012
Abstract 1885: Targeting the FOXO1/KLF6 transcriptional network to modulate response to anti-EGFR based therapy Cancer Research
06/04/2012
Abstract 1884: Resistance to second-line tyrosine kinase inhibitor treatment in imatinib-resistant Philadelphia-positive leukemia patients can be anticipated by ultra-deep sequencing of the BCR-ABL kinase domain using Roche 454 technology Cancer Research
06/04/2012
Abstract 1883: Pharmacogenetic analysis of the weekly paclitaxel/IP carboplatin combination therapy for ovarian and peritoneal cancers Cancer Research
06/04/2012
Abstract 1881: Integration of cell line and Cancer and Leukemia Group B 40101 clinical trial genome-wide association analyses implicates multiple loci in paclitaxel-induced peripheral neuropathy Cancer Research
06/04/2012
Abstract 1880: Incorporating protein levels with genetic variation and gene expression in sensitivity to chemotherapy Cancer Research
06/04/2012
Abstract 1879: The exomes of the NCI60 and their implications for cancer pharmacogenomics Cancer Research
06/04/2012
Abstract 1878: Upregulation of UGT1A4 by fulvestrant: A potential elimination mechanism of anastrazole in breast cancer treatment Cancer Research
06/04/2012
Abstract 1877: Predictive marker discovery for Sorafenib using patient derived xenograft models of hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 1876: Preclinical efficacy of fibroblast growth factor ligand trap HGS1036 in lung carcinoma models with genomic amplification of FGFR1 Cancer Research
06/04/2012
Abstract 1875: Identifying genetic variants contributing to cellular susceptibility to tamoxifen using a genome-wide cell-based model Cancer Research
06/04/2012
Abstract 1874: The role of functional polymorphisms in folate metabolism on 6-mercaptopurine-mediated hematological toxicity in children with acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 1872: Identification of novel single-nucleotide polymorphisms associated with anticancer drug effects using the SNPChip384 platform Cancer Research
06/04/2012
Abstract 1871: Role of CYP1B1 gene polymorphisms in anticancer drug cytotoxicity as studied on isogenic cell lines Cancer Research
06/04/2012
Abstract 3589: Comparative expression profile of transmembrane mucin MUC1 in breast cancer from American Indian and Caucasian women Cancer Research
06/04/2012
Abstract 3588: Treatment differences are associated with black-white disparities in advanced epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 3587: Effect of race on outcome in women with uterine cancers Cancer Research
06/04/2012
Abstract 3586: Epigenetic influence on ethnic disparities in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 3585: Second primary tumors after breast cancer: Results from the European Prospective Investigation into Cancer and Nutrition (EPIC) study Cancer Research
06/04/2012
Abstract 3584: Cardiovascular risk factors and co-morbid conditions among African-American and Caucasian breast cancer survivors Cancer Research
06/04/2012
Abstract 3583: Elevated inflammatory and hematological markers and survival in patients with renal cell carcinoma Cancer Research
06/04/2012
Abstract 3582: Genetic polymorphisms in NAT2 gene influence overall survival in bladder cancer patients Cancer Research
06/04/2012
Abstract 3581: Long-term results of organ sparing surgical treatments of precancerous cervical lesions in Mongolia Cancer Research
06/04/2012
Abstract 3580: Pre-diagnostic alcohol consumption and breast cancer recurrence and survival in postmenopausal women Cancer Research
06/04/2012
Abstract 3579: Prognostic and predictive role of JWA and XRCC1 expression in gastric cancer Cancer Research
06/04/2012
Abstract 3578: The use of preventive services among prostate cancer survivors Cancer Research
06/04/2012
Abstract 3577: A decade of changed behavior: Trends in screening adherence and incidence 2000-2010 Cancer Research
06/04/2012
Abstract 3575: The effects of selection bias by lung cancer screening Cancer Research
06/04/2012
Abstract 3574: Detection of serum CYFRA 21-1 as a biomarker for stratification of ovarian cancer risk in women with a pelvic mass Cancer Research
06/04/2012
Abstract 3573: Urine and serum biomarkers as early detection tools for ovarian cancer Cancer Research
06/04/2012
Abstract 3572: Methylated gene marker levels in stool: effects of demographic, drug, and body mass and other patient characteristics Cancer Research
06/04/2012
Abstract 3571: UKLS - United Kingdom Lung Cancer Screening Trial Cancer Research
06/04/2012
Abstract 3570: Cervical cancer screening practices among Hispanic migrant and seasonal farmworkers of Michigan Cancer Research
06/04/2012
Abstract 3569: Age distribution at prior benign biopsy (PBB) in breast cancer patients and implications for risk biomarker discovery Cancer Research
06/04/2012
Abstract 3568: Progression from benign breast disease to cancer in women with a family history of breast cancer Cancer Research
06/04/2012
Abstract 3567: Loss of heterozygosity (LOH) profiles predict oral cancer recurrence in the Oral Cancer Recurrence Prediction Cohort Cancer Research
06/04/2012
Abstract 3566: Multimodal optical imaging for detection of oral neoplasia Cancer Research
06/04/2012
Abstract 3565: Colorectal cancer screening among US adults with and without doctor's specific recommendation regarding choice of screening modality Cancer Research
06/04/2012
Abstract 3564: A Phase II randomized trial of lycopene-rich tomato extract among men with high-grade prostatic intraepithelial neoplasia (HGPIN) Cancer Research
06/04/2012
Abstract 3563: Soy protein isolate consumption does not prevent biochemical failure after radical prostatectomy in high risk men: A randomized controlled trial Cancer Research
06/04/2012
Abstract 3562: Overweight, inflammation of normal colorectal mucosa, and cancer risk. Cancer Research
06/04/2012
Abstract 3561: Effects of metformin on markers of insulin resistance and on breast cancer proliferation: The putative role of IGFBP-1 as a predictive biomarker Cancer Research
06/04/2012
Abstract 3560: Application of metabolomics to assess serum profiles in limonene-treated breast cancer patients Cancer Research
06/04/2012
Abstract 3559: Gene-expression changes in adipose tissue with diet- and/or exercise-induced weight loss: a randomized controlled trial Cancer Research
06/04/2012
Abstract 3558: A pilot clinical study of limonene in women with early stage breast cancer: Effects of short-term treatment on tissue limonene disposition and serum markers Cancer Research
06/04/2012
Abstract 3557: Reduced ovarian hormones & reduced mammographic & MRI determined breast density in BRCA carriers following a hormonal chemo-prevention regimen of gonadotropin releasing hormone agonist (GnRHA) & low-dose add-back estrogen & testosterone Cancer Research
06/04/2012
Abstract 3556: Administration of omega-3 fatty acids and raloxifene individually and in combination to women at high risk of breast cancer: Interim feasibility data and biomarker analysis from a randomized clinical trial Cancer Research
06/04/2012
Abstract 3555: Histone deacetylase 6 as a novel regulator of the immunogenicity and aggressiveness of melanoma Cancer Research
06/04/2012
Abstract 3554: The histone deacetylase inhibitor LBH589 augments anti-tumor immunity through direct effects on tumor and immune cells leading to impaired tumor progression in vivo Cancer Research
06/04/2012
Abstract 3553: Modulation of pro-inflammatory signaling pathways by aging T-lymphocytes contributes to a more malignant phenotype in prostate epithelial cells Cancer Research
06/04/2012
Abstract 3552: Cancer immunoediting: Profile of cytokines in a mammary adenocarcinoma tumor model Cancer Research
06/04/2012
Abstract 3550: Differences in immune escape in HPV+ versus HPV- head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 3549: DeltaNp63 overexpression induced cytokines and chemokines attract type2 suppressive inflammatory infiltrates through NF-kappaB activation in dysplastic and malignant epithelia Cancer Research
06/04/2012
Abstract 3547: Disruption of Galectin1-glycan interaction impairs tumor growth and metastasis in breast cancer by disarming the immunosuppressive capacity of regulatory T cells Cancer Research
06/04/2012
Abstract 3546: IL-17 production by tumor-infiltrating Th17 cells favors inflammation and promotes survival in human colorectal cancer Cancer Research
06/04/2012
Abstract 3545: Neutrophils regulate effector and inhibitory T cell function in prostate cancer Cancer Research
06/04/2012
Abstract 3544: Role of tumor-infiltrating gammadelta T lymphocytes in breast cancer Cancer Research
06/04/2012
Abstract 3543: Complete regression of solid B16F1 melanoma tumors obtained by intratumoral injection of LTX-315 (Oncopore(R)) Cancer Research
06/04/2012
Abstract 3542: Interplay between cancer and the immune system: Beneficial role of TILs and mechanisms of tumor immune escape in GBM patients Cancer Research
06/04/2012
Abstract 3541: CD4+ T cells infiltrating human breast cancer are critical for an effective anti-tumor immune response Cancer Research
06/04/2012
Abstract 3540: Prostate cancer-infiltrating mast cells suppress anti-tumor immunity through a TGF{beta} and IL-13 dependent mechanism Cancer Research
06/04/2012
Abstract 3539: Anti-CSF-1R antibodies reduce tumor-associated macrophages and inhibit tumor growth in preclinical models Cancer Research
06/04/2012
Abstract 3538: The HIF-1{alpha} hypoxia response in mouse tumor-infiltrating T lymphocytes induces functional CD137 (4-1BB) for immunotherapy Cancer Research
06/04/2012
Abstract 3537: Manipulation of local and systemic immune suppression by GPI-anchored immune stimulatory proteins Cancer Research
06/04/2012
Abstract 3535: Lymphoma-associated macrophages benefit for tumor progress via overexpressing legumain to degrade extracellular matrix in diffuse large B-cell lymphoma Cancer Research
06/04/2012
Abstract 3534: Human Th17 cells have stem cell-like features and promote long-term tumor immunity Cancer Research
06/04/2012
Abstract 3533: Acquisition of antigen presenting cell functions by V{gamma}9V{alpha}2-T cells requires trogocytosis Cancer Research
06/04/2012
Abstract 3532: The effect of B cell depletion on tumor phenotype Cancer Research
06/04/2012
Abstract 3531: Papillary thyroid carcinomas with and without lymph node metastasis show differences in tumor-infiltrating leukocytes Cancer Research
06/04/2012
Abstract 3530: Lipid accumulation inhibits DC ability for cross-presentation of antigens in tumor-bearing mice Cancer Research
06/04/2012
Abstract 3529: A direct mass spectrometry approach for HPV T cell epitope identification Cancer Research
06/04/2012
Abstract 3528: IMCmage1: A novel bi-specific biologic re-directing T cells to kill MAGE-A3/A6 presenting cancers Cancer Research
06/04/2012
Abstract 3527: Potent anti-tumor activity of AbGn-100, an anti-CD326 x anti-TCR bispecific antibody to CD326-expressing solid tumors Cancer Research
06/04/2012
Abstract 3526: Subcutaneous administration of PSMA/CD3-bispecific BiTE antibody MT112/BAY 2010112 leads to complete remission of human prostate cancer xenografts in mice Cancer Research
06/04/2012
Abstract 3525: IMCgp100: A novel bi-specific biologic for the treatment of malignant melanoma Cancer Research
06/04/2012
Abstract 3524: A novel approach to targeting mutated colorectal adenocarcinomas with T cell-engaging CEA/CD3-bispecific BiTE investigational antibody MEDI-565 Cancer Research
06/04/2012
Abstract 3523: Preclinical characterization of MT114, a novel CD33/CD3-bispecific BiTE antibody for the treatment of acute myeloid leukemia (AML) Cancer Research
06/04/2012
Abstract 3522: Preclinical development of an anti-CD30/anti-CD16A bispecific tetravalent TandAb antibody for the treatment of Hodgkin lymphoma Cancer Research
06/04/2012
Abstract 3521: RECRUIT-TandAb AFM13: Overcoming limitations of monoclonal antibodies in Hodgkin lymphoma Cancer Research
06/04/2012
Abstract 3520: Targeting spatiotemporal expression of CD137 on tumor-specific cytotoxic T lymphocytes as a novel strategy for agonistic antibody therapy Cancer Research
06/04/2012
Abstract 3519: Appropriate crosslinking is required for co-stimulatory activity of human CD27 antibody in a transgenic mouse model Cancer Research
06/04/2012
Abstract 3518: Cellular therapy in combination with cytokines improves survival in a xenograft mouse model of ovarian cancer Cancer Research
06/04/2012
Abstract 3517: Use of a novel synthetic biomaterial to induce mild whole body hyperthermia for the treatment of cancer in a preclinical model Cancer Research
06/04/2012
Abstract 3516: Evaluation of whole body hyperthermia system: changes of core body temperature and their effects on immune system Cancer Research
06/04/2012
Abstract 3515: Maitake D-Fraction, a natural mushroom extract, synergizes with Interleukin-2 for increased lytic activity of peripheral blood mononuclear cells against various human tumor cell histologies Cancer Research
06/04/2012
Abstract 3514: Ex vivo activation and expansion of natural killer cells from advanced cancer patients with feeder cells from healthy volunteers Cancer Research
06/04/2012
Abstract 3513: The anti-tumor effect of activated natural killer cells in xenograft mouse models with epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 3512: Expanded human regulatory iNKT cells exhibit direct cytotoxicity against hematolymphoid tumor targets Cancer Research
06/04/2012
Abstract 3511: Genetically engineered natural killer (NK) cell immunotherapy for poor risk B-cell (CD20+) leukemia and lymphoma (L/L) Cancer Research
06/04/2012
Abstract 3509: Intracranial administration of activated NK-cells and mAb9.2.27 against NG2/CSPG4 activates microglial cytotoxicity and prolongs survival in glioblastoma xenograft model Cancer Research
06/04/2012
Abstract 3507: Type 17-1-CD8+ T cells (Tc17-1) as potent effector cells for immunotherapy of brain tumors Cancer Research
06/04/2012
Abstract 3506: IL-15 or IL-15/IL-15R{alpha} complexes activates natural killer cells and enhances anti-GD2 monoclonal antibody-mediated antibody-dependent cellular cytotoxicity in vitro and in vivo Cancer Research
06/04/2012
Abstract 3505: Preclinical testing of mRNA engineered chimeric antigen receptor T cells: Comparison of a multi-infusion protocol to a single injection of stably expressed CARs in ALL xenograft models Cancer Research
06/04/2012
Abstract 3504: Generation and optimization of a chimeric antigen receptor against human CD22: A new immunotherapeutic agent for adoptive immunotherapy Cancer Research
06/04/2012
Abstract 3503: Enhanced delivery of T cells to tumor after chemotherapy using membrane-anchored, apoptosis-targeted peptide Cancer Research
06/04/2012
Abstract 3502: Short-term cytolytic assays are not predictive of chimeric antigen receptor anti-tumor activity mediated by some T cell subsets Cancer Research
06/04/2012
Abstract 3501: Binary control of CAR-CTL by transgenic IL-7 and IL-7R expression Cancer Research