Medical Research Articles Published in June 2012

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06/04/2012
Abstract 3445: Targeting Thromboxane A2 receptor (TP) to block breast cancer metastasis Cancer Research
06/04/2012
Abstract 3444: Exon 4 of osteopontin: A unique target to reduce malignant behavior in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 3443: CXCR2 inhibition decreases invasion and metastasis of a KRAS/p53-mutant lung adenocarcinoma cell line in vitro and in vivo Cancer Research
06/04/2012
Abstract 3442: Overexpression of Kruppel-like factor 4 inhibits the growth and migration in human hepatoma cells Cancer Research
06/04/2012
Abstract 3441: Silencing glucosylceramide synthase using MBO-asGCS eliminates tumor metastasis Cancer Research
06/04/2012
Abstract 3440: Effect of neoadjuvant therapy for the number of lymph node micrometastasis in esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 3437: A natural plant product to inhibit breast cancer metastasis Cancer Research
06/04/2012
Abstract 3436: Suppression of the epithelial-mesenchymal transition (EMT) by a wound-healing gene, Grainyhead-like-2 Cancer Research
06/04/2012
Abstract 3435: NM23-H1 suppresses melanoma cell motility by promoting strong adhesions between fibronectin and {alpha}4{alpha}1 integrin Cancer Research
06/04/2012
Abstract 3434: EphB3 mediates kinase-dependent suppression of non-small cell lung cancer metastasis Cancer Research
06/04/2012
Abstract 3433: Molecular regulation of RKIP, a tumor metastasis suppressor in breast cancer Cancer Research
06/04/2012
Abstract 3432: HLJ1 serves as an inhibitor of epithelial-mesenchymal transition by inactivating {beta}-catenin signaling Cancer Research
06/04/2012
Abstract 3431: Prostate-derived ETS factor expression decreases prostate tumor cell aggressiveness in vitro and metastasis in vivo Cancer Research
06/04/2012
Abstract 3429: AKAP12/SSeCKS inhibits peritoneal metastasis by regulating chemokine production Cancer Research
06/04/2012
Abstract 3428: Genome-stabilizing functions of NM23 in metastatic melanoma Cancer Research
06/04/2012
Abstract 3427: Interaction of two metastasis suppressors, Nm23-H1 and Gelsolin, in the proliferation and motility of MDA-MB-231 breast carcinoma cells Cancer Research
06/04/2012
Abstract 3426: E-cadherin regulates 'stemness' and 'bone metastasis' of prostate cancer cells Cancer Research
06/04/2012
Abstract 3425: Prognostic significance of BRMS1 promoter methylation in operable breast cancer Cancer Research
06/04/2012
Abstract 3424: Cancer cells lose their expression of lipoxygenases in order to activate pro-survival and angiogenic pathways thereby establishing successful macro-metastases Cancer Research
06/04/2012
Abstract 3423: RRP1B, a novel metastasis suppressor, interacts with mRNA splicing factors and regulates alternative mRNA splicing Cancer Research
06/04/2012
Abstract 3421: Nm23, a metastasis suppressor gene, binds the cytoskeletal linker Ezrin to regulate motility Cancer Research
06/04/2012
Abstract 3420: A survival-associated polymorphism within metastasis suppressor RRP1B directs RRP1B-chromatin interactions and self-regulation of gene expression Cancer Research
06/04/2012
Abstract 3419: N-myc downstream regulated gene 1, NDRG1, modulates Wnt-{beta}-catenin signaling and pleiotropically suppresses metastasis Cancer Research
06/04/2012
Abstract 3418: Regulation of Dicer expression by Sox4 and its role in melanoma cell invasion and patient survival Cancer Research
06/04/2012
Abstract 3417: An in vivo functional screen to identify metastasis suppressor genes Cancer Research
06/04/2012
Abstract 3415: Development of a new circulating tumor cell detection and isolation assay based on automated on-chip imaging flow cytometry technology Cancer Research
06/04/2012
Abstract 3414: Role of FGFR2 in invasion and metastasis through different activation of downstream signaling in gastric cancer Cancer Research
06/04/2012
Abstract 3413: A population of metastatic colorectal cancer (mCRC) patients with radiologically proven liver metastasis and EpCAM expressing primary tumors show low circulating tumor cell counts by Veridex Cellsearch Cancer Research
06/04/2012
Abstract 3412: Quadruple immunofluorescence protocol for identification of the metastatic potential of prostate CTCs Cancer Research
06/04/2012
Abstract 3410: Identification of frequently gained genomic regions in breast circulating tumor cells Cancer Research
06/04/2012
Abstract 3409: Generation of mRNA and miRNA gene expression profiles in circulating tumor cells of metastatic colorectal cancer patients Cancer Research
06/04/2012
Abstract 3408: Gene expression profiling of MCF10A series of Ha-Ras transformed human breast epithelial cells: Gene expression involved in EMT pathway Cancer Research
06/04/2012
Abstract 3407: Analysis of the MET dependent proteins expression in cervical carcinoma cell lines Cancer Research
06/04/2012
Abstract 3406: Impact of TJP-1 and TWIST expression on post-operative prognosis in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 3404: Exploring the role of Twist1 in the pathogenesis of malignant pleural mesothelioma (MPM) Cancer Research
06/04/2012
Abstract 3403: E-cadherin and vimentin patterns by immunohistochemistry identify epithelial and mesenchymal phenotypes in lung adenocarcinoma Cancer Research
06/04/2012
Abstract 3402: Clinical implication of epithelial to mesenchymal transition (EMT) in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 3401: Amplification of the STOML3, FREM2, and LHFP genes is associated with mesenchymal differentiation in gliosarcoma Cancer Research
06/04/2012
Abstract 3399: Detection of rare mutations in plasma by droplet digital PCR Cancer Research
06/04/2012
Abstract 3398: High-throughput expression profiling of circulating tumor cells from breast cancer patients as potential therapy decision indicator Cancer Research
06/04/2012
Abstract 3397: Patterns of DNA copy number changes in colorectal cancer metastasis are highly similar to their corresponding primaries with additional focal alterations that differ between individual patients Cancer Research
06/04/2012
Abstract 3396: Predictive value of metastatic lymph node ratio in diagnosis of recurrence after surgical resection of gastric cancer Cancer Research
06/04/2012
Abstract 3394: Identification of PRDX4 and P4HA2 as metastasis-associated proteins in oral cavity squamous cell carcinoma by comparative tissue proteomics of microdissected specimens using iTRAQ technology Cancer Research
06/04/2012
Abstract 3393: Antibody-based array proteomics identify proteins differentially expressed in human metastatic and non-metastatic triple negative breast cancer cells Cancer Research
06/04/2012
Abstract 3392: Molecular determinants for the bone-metastatic potential of prostate cancer cells Cancer Research
06/04/2012
Abstract 3391: Interaction of microRNAs and target genes in bladder cancer metastasis Cancer Research
06/04/2012
Abstract 3390: Delineating the molecular signature of the breast cancer-induced brain metastasis and the role of a novel pan-TGF-{beta} inhibitor to block brain metastasis in a mouse xenograft model Cancer Research
06/04/2012
Abstract 3389: Determining optimal conditions for collection and processing of metastatic liver biopsies collected for a multicenter, prospective study to identify biomarkers of clinical resistance to first-line therapy in metastatic colorectal cancer Cancer Research
06/04/2012
Abstract 3387: Secreted exosomes from cultured bladder cells are enriched for distinct miRNAs detected in circulation of metastatic bladder cancer patients Cancer Research
06/04/2012
Abstract 3386: Molecular profiling of breast cancer organ-specific metastases Cancer Research
06/04/2012
Abstract 3385A: Synergistic effect of purified components from Antrodia Cinnamomea Mycelia on targeting oral cancer stem cell Cancer Research
06/04/2012
Abstract 3385: Expression of CD22, a late B lymphoid antigen, does not distinguish leukemia stem cells from the bulk population in acute lymphoblastic leukemia cases Cancer Research
06/04/2012
Abstract 3384: High ALDH activity is associated with high tumorigenicity in prostate cancer Cancer Research
06/04/2012
Abstract 3383: Expression and role of BORIS/CTCFL in human cancer stem cells Cancer Research
06/04/2012
Abstract 3382: A systematic approach to the study of cancer stem cells applied to ovarian cancer Cancer Research
06/04/2012
Abstract 3381: Photochemical internalization (PCI) of immunotoxins targeting cancer stem cell markers Cancer Research
06/04/2012
Abstract 3380: Comparison proteome analysis of scirrhous gastric carcinoma stem cell-like SP and hypoxia-resistant cell lines Cancer Research
06/04/2012
Abstract 3379: Adaptation of soft agar colony formation assays to identify agents which block proliferation of putative colon cancer stem cells Cancer Research
06/04/2012
Abstract 3378: Metformin protects head and neck cancer stem cells against DNA damage induced apoptosis Cancer Research
06/04/2012
Abstract 3377: Oncolytic herpes simplex virus treatment of malignant peripheral nerve sheath tumor (MPNST) cancer stem-like cell orthotopic tumor model Cancer Research
06/04/2012
Abstract 3376: Cord blood stem cells revert EMT to MET in glioma stem cells by downregulating synergistic transcriptional activation of Sox2 and Twist1 Cancer Research
06/04/2012
Abstract 3374: Characterizing a new population of adult mouse submandibular gland stem cells Cancer Research
06/04/2012
Abstract 3373: Identification of the stem cells in the epithelium of human Fallopian tube Cancer Research
06/04/2012
Abstract 3372: Mouse keratinocyte side-population plays an important role during malignant progression to skin squamous cell carcinomas Cancer Research
06/04/2012
Abstract 3371: Targeting glioblastoma stem cell pathways through phage display screening Cancer Research
06/04/2012
Abstract 3370: DNA repair in glioma stem cell-mediated radiation resistance Cancer Research
06/04/2012
Abstract 3368: Efficient delivery of prostate cancer gene therapy via adipose-derived mesenchymal stem cells in vivo Cancer Research
06/04/2012
Abstract 3367: Breast cancer stem cell-like cells are sensitive to ionizing radiation: Role of ATM Cancer Research
06/04/2012
Abstract 3366: An inhibitor of the NF-kappaB pathway targets cancer stem cells and prevents tumor recurrence Cancer Research
06/04/2012
Abstract 3365: Histone deacetylase inhibitor differentially regulates stemness gene expression in neuroblastoma drug resistant cells Cancer Research
06/04/2012
Abstract 3364: Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma (MCL) via manipulation of tissue transglutaminase activities. Cancer Research
06/04/2012
Abstract 3363: Brain tumor stem-like cells as a tool for testing small molecules for anti-tumor therapy Cancer Research
06/04/2012
Abstract 3362: Tumor initiating cells are sensitive to paclitaxel encapsulated in polymeric nanoparticles Cancer Research
06/04/2012
Abstract 3361: Sensitization of chemoresistant H1650 lung cancer stem cells to chemotherapy by combination treatment with novel diindolylmethane compounds Cancer Research
06/04/2012
Abstract 3360: The hedgehog pathway inhibitor GDC-0449 alters intracellular Ca2+-homeostasis and inhibits cell growth in cisplatin-resistant lung cancer cells Cancer Research
06/04/2012
Abstract 3358: 1{alpha},25-dihydroxyvitamin D3 inhibits the proliferation of cultured glioblastoma multiforme cells Cancer Research
06/04/2012
Abstract 3357: Targeting cancer stem cells by an anti-DLL4 antibody inhibits epithelial-to-mesenchymal transition, delays tumor recurrence and overcomes drug resistance in breast and pancreatic cancer Cancer Research
06/04/2012
Abstract 3356: Development of a novel Wnt pathway antagonist antibody, OMP-18R5, that reduces tumor initiating cell frequency in breast cancer Cancer Research
06/04/2012
Abstract 3355: Signaling networks in pancreatic cancer cells with stem cell characteristics Cancer Research
06/04/2012
Abstract 3354: Investigating the role of Nodal in the regulation of integrin {alpha}6{beta}4high trophoblast progenitor cells Cancer Research
06/04/2012
Abstract 3353: Nodal signaling mediates the aggressive, tumorigenic phenotype in breast cancer cells Cancer Research
06/04/2012
Abstract 3352: The medulloblastoma oncogene Otx2 enhances migration and permits ectopic proliferation of neuronal progenitor cells of the cerebellum and brainstem Cancer Research
06/04/2012
Abstract 3351: Cord blood stem cells inhibit epidermal growth factor receptor translocation to mitochondria in glioblastoma Cancer Research
06/04/2012
Abstract 3350: Implications of the STAT6 pathway by interleukin-4 in prostate cancer Cancer Research
06/04/2012
Abstract 3349: Transformation of mammary epithelial cells by inactivation of p53 and PTEN generates cancer stem cells driven by an IL-6/TGF-beta inflammatory loop Cancer Research
06/04/2012
Abstract 3348: Pax8-PPAR{delta} fusion protein activates {beta}-catenin/TCF pathways Cancer Research
06/04/2012
Abstract 3347: A proneural signature profile predicts response to Notch inhibition in glioma stem cells Cancer Research
06/04/2012
Abstract 3346: Astrocytoma initiation by Rb family inactivation induced dedifferentiation of mature astrocytes. Cancer Research
06/04/2012
Abstract 3343: Upregulation of SOX5 perturbs human glioma cell proliferation and is associated with proneural glioblastoma Cancer Research
06/04/2012
Abstract 3342: Tumor-initiating cells in human glioblastoma are heterogeneous populations which reside in distinct environmental niches Cancer Research
06/04/2012
Abstract 3341: Chronic TNF{alpha} treatment enhances cancer stem cell-like phenotype via Notch1 activation in oral squamous cell carcinoma cells Cancer Research
06/04/2012
Abstract 3340: Prolactin hormone signaling promotes cancer stem cell niche and migration in colorectal cancer Cancer Research
06/04/2012
Abstract 3339: The role of active Notch signaling in glioblastoma neurosphere cultures Cancer Research
06/04/2012
Abstract 3338: Characterization of glucose transporter 3 in head and neck cancer initiating cells Cancer Research
06/04/2012
Abstract 3337: TGF-{beta} from niche fibroblasts increases the stemness cancer stem cell-like side population cells in gastric cancer Cancer Research
06/04/2012
Abstract 3336: The role of Notch signaling in esophageal adenocarcinoma Cancer Research
06/04/2012
Abstract 3335: The potential role of lateral inhibition in the maintenance of glioblastoma cancer stem cells Cancer Research
06/04/2012
Abstract 3334: Antiangiogenic activity of honokiol through inhibition of vascular vessel formation in the mouse embryonic stem cell-derived endothelial cells Cancer Research
06/04/2012
Abstract 3332: Inhibition of cancer stem-like properties in malignant glioma by delivery of microRNA145 with cationic polyurethanes-PEI Cancer Research
06/04/2012
Abstract 3331: MicroRNAs regulate breast cancer stem cells and spontaneous metastases in orthotopic xenograft models Cancer Research
06/04/2012
Abstract 3329: A let-7 signaling pathway targets metastatic genes enriched in tumor initiating cells Cancer Research
06/04/2012
Abstract 3328: Targeted inactivation of EZH2 by CDF inhibits pancreatic tumor growth mediated by re-expression of lost miRNAs in tumors Cancer Research
06/04/2012
Abstract 3327: Role of microRNA221 in breast cancer stem cell expansion and induction of EMT Cancer Research
06/04/2012
Abstract 3326: {Delta}Np63{alpha} is a regulator of epithelial-mesenchymal transition in human keratinocytes Cancer Research
06/04/2012
Abstract 3325: The role of MyD88 in chemoresistance, differentiation and hypoxia in cancer stem cells Cancer Research
06/04/2012
Abstract 3324: Cyclooxygenase-2 mediated breast cancer progression by induction of stem like cells and micro RNA Cancer Research
06/04/2012
Abstract 3323: Hyaluronan synthase 2 promotes breast cancer bone metastasis by stimulating interaction of cancer stem-like cells with tumor-associated macrophage Cancer Research
06/04/2012
Abstract 3322: Phenotypic plasticity in the normal breast Cancer Research
06/04/2012
Abstract 3321: Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma Cancer Research
06/04/2012
Abstract 3320: Plasticity between the cancer stem-like and non cancer stem-like states is regulated by the PI3K/Akt/{beta}-catenin/CBP pathway Cancer Research
06/04/2012
Abstract 3319: CD44 standard isoform regulates the mesenchymal phenotype in hepatocellular carcinoma cells, and associates with a poor prognosis in patients. Cancer Research
06/04/2012
Abstract 3318: Phenotypic heterogeneity and instability of tumor-initiating cells in high-grade serous cancer Cancer Research
06/04/2012
Abstract 3317: The roles of TMCC3 in breast cancer cells Cancer Research
06/04/2012
Abstract 3316: The stem cell marker nestin inhibits growth and invasion of malignant melanoma Cancer Research
06/04/2012
Abstract 3315: Malignant melanoma cells reciprocate aspects of the embryonic neural crest migration program to promote invasion and increased plasticity Cancer Research
06/04/2012
Abstract 3314: Phenotypic plasticity in glioma stem cells mediated by NF{kappa}B signaling Cancer Research
06/04/2012
Abstract 3313: Novel roles of CCN6 in mesenchymal-epithelial transition (MET) and loss of stem cell properties of breast cancer cells Cancer Research
06/04/2012
Abstract 3312: Targeting Notch signaling to abrogate the increase in breast cancer stem cells induced by hypoxia Cancer Research
06/04/2012
Abstract 3311: Role of nicastrin in the maintenance of breast cancer stem cells and invasion Cancer Research
06/04/2012
Abstract 3310: microRNAs regulate the transition between EMT and MET breast cancer stem cell states Cancer Research
06/04/2012
Abstract 3309: Blocking the Notch pathway inhibits the epithelial-mesenchymal transition (EMT) status in lung cancer and alters chemoresistance Cancer Research
06/04/2012
Abstract 3308: Axl is required for EMT-induced stem cell traits and metastasis in breast cancer Cancer Research
06/04/2012
Abstract 3307: Improved survival in AML by in vivo drug targeting of conserved regulatory pathways in phenotypically distinct tumor-initiating compartments Cancer Research
06/04/2012
Abstract 3306: A novel reconstructed metastasis (rMet) model to understand the role of breast cancer stem cells in metastasis Cancer Research
06/04/2012
Abstract 3305: The role of carbonic anhydrase IX in tumor hypoxia, metastasis and the cancer stem cell niche Cancer Research
06/04/2012
Abstract 3304: Hyaluronan mediates interactions between CD44+ MSCs and CD34+ fibrocytes in Desmoid Tumors. Cancer Research
06/04/2012
Abstract 3290: A novel model of breast cancer metastasis: Killing two birds with one stone Cancer Research
06/04/2012
Abstract 3289: Tissue specific expression of the PI 3-kinase mutation Pik3caH1047R induces hyperplasia and tumorigenesis in a mouse model Cancer Research
06/04/2012
Abstract 3288: A chromosome engineering mouse model to identify mechanisms by which duplication of 8q24 promotes human breast cancer Cancer Research
06/04/2012
Abstract 3287: Intra- and intercellular Wnt pathway induction synergistically accelerates FGFR1-mediated prostate tumorigenesis Cancer Research
06/04/2012
Abstract 3286: Interleukin-17 receptor c (IL-17RC) knockout mice developed fewer and smaller prostate tumors compared to the wild-type mice in Pten-deficient context Cancer Research
06/04/2012
Abstract 3284: Organ-specific Gst-pi expression in new metastatic androgen-independent prostate cancer animal model Cancer Research
06/04/2012
Abstract 3283: Conditional Low-molecular-weight (LMW) cyclin E-induced mammary tumorigenesis Cancer Research
06/04/2012
Abstract 3282: Does the catalytic activity of prostate-specific antigen (PSA) or kallikrein-related peptidase 2 (hK2) secreted by novel transgenic mice models critically influence development of prostate cancer or release of PSA or hK2 in blood Cancer Research
06/04/2012
Abstract 3281: Development of a novel transgenic mouse model for prostate cancer Cancer Research
06/04/2012
Abstract 3280: Loss of the tumor suppressor APC in cells expressing lysozyme M results in murine endometrial hyperplasia Cancer Research
06/04/2012
Abstract 3279: Potential beneficial effects of the BRCA1 mutation carrier state on bone strength Cancer Research
06/04/2012
Abstract 3278: Sustained multilocular adipose tissue phenotype in adult Brca1 mutant mouse mammary gland is correlated with an increase in BMP7 Cancer Research
06/04/2012
Abstract 3277: Increased mitogen-activated protein kinase kinase 4 (MEK4) induces metastasis in an orthotopic murine model of prostate cancer Cancer Research
06/04/2012
Abstract 3276: A novel in vivo xenograft mouse model of human high-grade serous ovarian cancer, with clinical, molecular and functional annotation relevant for pre-clinical analysis Cancer Research
06/04/2012
Abstract 3273: A robust transgenic mouse model to study male breast cancer Cancer Research
06/04/2012
Abstract 3272: Characterization of mouse oviductal glycoprotein (Ovgp1) promoter driven SV40 T large antigen: fallopian tube cancer and leiomyosarcoma mouse model Cancer Research
06/04/2012
Abstract 3271: Targeting fibroblast growth factor receptor 4 decreases prostate cancer growth and metastasis Cancer Research
06/04/2012
Abstract 3270: The effect of soy exposure in different ages on the mammary tumor development of the MMTV-ErbB-2 transgenic mice Cancer Research
06/04/2012
Abstract 3269: Basal VEGF protein expression in skeletal muscle, adipose tissue and mammary tumors of PyMT mice Cancer Research
06/04/2012
Abstract 3267: Mammalian target of rapamycin (mTOR) signaling proteins are highly expressed in mamamry tumors of MMTV-TGF-{beta} mice Cancer Research
06/04/2012
Abstract 3266: Interaction of MCM7 and RACK1 for activation of MCM7 and cell growth Cancer Research
06/04/2012
Abstract 3265: PMA induces malignant characteristics in MCF-7 breast cancer cells via MAPK-pathway Cancer Research
06/04/2012
Abstract 3264: Downregulation of intersectin-1s in human lung cancer may contribute to tumorigenesis Cancer Research
06/04/2012
Abstract 3263: Expression of Bim, Noxa, and Puma in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 3261: GRP78 regulates clusterin stability, retrotranslocation, and mitochondrial localization under ER stress in prostate cancer Cancer Research
06/04/2012
Abstract 3260: Primary cilia are lost early in prostate cancer progression Cancer Research
06/04/2012
Abstract 3259: TGF{beta} signaling is frequently attenuated in hepatocellular carcinomas but is retained for malignant phenotypes in some hepatocellular carcinoma cells Cancer Research
06/04/2012
Abstract 3258: Targeted-deletion of Ptp4a3 suppresses murine colon tumorigenesis Cancer Research
06/04/2012
Abstract 3257: Nodal signalling in choriocarcinoma cells Cancer Research
06/04/2012
Abstract 3256: Sphingolipid regulation by sphingosine kinase anchoring protein (SKAP) and its implication in cancer Cancer Research
06/04/2012
Abstract 3255: IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 3254: Cadherin-11 function is required for full neoplastic transformation by v-Src Cancer Research
06/04/2012
Abstract 3253: Bone morphogenetic proteins increase hepcidin in breast cancer cells Cancer Research
06/04/2012
Abstract 3252: Divergence of activin and TGF{beta}-induced SMAD-independent signaling in colon cancer Cancer Research
06/04/2012
Abstract 3251: Linking prostaglandin E2 signaling, lipid rafts, and DNA protein kinase Cancer Research
06/04/2012
Abstract 3250: Chondroitin sulfate-mediated regulation of Wnt/{beta}-catenin signaling in breast cancer Cancer Research
06/04/2012
Abstract 3249: Intersectin 1 is required for neuroblastoma tumorigenesis Cancer Research
06/04/2012
Abstract 3248: Amphiregulin interacts with Wnt signaling to regulate cancer cell growth and survival Cancer Research
06/04/2012
Abstract 3247: Identification of a novel TAZ/TEAD/BMP4/Smad1,5 signaling axis Cancer Research
06/04/2012
Abstract 3246: TMS1 / ASC is critical for primary ciliogenesis and participates in cell migration Cancer Research
06/04/2012
Abstract 3244: Compensatory function of the homologous proteins MIF and D-DT in regulation of AMPK-dependent metabolic-stress pathways in non-small cell lung carcinoma Cancer Research
06/04/2012
Abstract 3243: Dysfunctional of TGF-{beta} signaling via loss of {beta}2SP activates SOX9 and C-MYC via Notch signaling in Barrett's esophageal adenocarcinoma Cancer Research
06/04/2012
Abstract 3242: Wnt secretion is required for colon cancer cell survival Cancer Research
06/04/2012
Abstract 3241: Analysis of transcription factor activation by the embryonic microenvironment in metastatic breast cancer cells Cancer Research
06/04/2012
Abstract 3240: The Wnt secretion factor Evi/Wls/Gpr177 promotes glioma tumorigenesis Cancer Research
06/04/2012
Abstract 3239: The Notch pathway as a new target in gastrointestinal stromal tumors Cancer Research
06/04/2012
Abstract 3237: XRay structure of human glutaminase in complex with BPTES and analysis of BPTES-resistant mutants Cancer Research
06/04/2012
Abstract 3236: Small molecule inhibitors of choline kinase lead to reduced phosphocholine levels and induction of apoptosis in cancer cells Cancer Research
06/04/2012
Abstract 3235: The IGF1 inhibitor BMS-754807 synergizes with Lapatinib in colorectal cancer cell lines Cancer Research
06/04/2012
Abstract 3234: Metformin shifts prostate cancer metabolism towards a less malignant phenotype Cancer Research
06/04/2012
Abstract 3233: Lovastatin decreases ovarian cancer cell proliferation and invasion: A case for statin therapy for ovarian cancer patients? Cancer Research
06/04/2012
Abstract 3231: A small molecule inhibitor of glucose transporter 1 (Glut1) down-regulates glycolysis, induces cell cycle arrest, and inhibits cancer cell growth in vitro and in vivo Cancer Research
06/04/2012
Abstract 3230: Fenofibrate-mediated energy crisis and apoptotic cell death of glioblastoma Cancer Research
06/04/2012
Abstract 3229: Energy restriction caused by the glycolytic inhibitor, 2-Deoxy-D-Glucose inhibits chemical induced carcinogenesis in mice Cancer Research
06/04/2012
Abstract 3226: PKM2 metabolic activator slows lung cancer xenograft growth Cancer Research
06/04/2012
Abstract 3225: Growth inhibition of glycolytic tumors by targeting basigin/lactate-H+ symporters (MCTs): Metformin sensitizes MCT inhibition Cancer Research
06/04/2012
Abstract 3224: Pre-clinical targeting of the metabolic phenotype of lymphoma by AZD3965, a selective inhibitor of monocarboxylate transporter 1 (MCT1) Cancer Research
06/04/2012
Abstract 3223: Magnetic resonance spectroscopic imaging of lactate in LDH-A silenced metastatic breast tumors Cancer Research
06/04/2012
Abstract 3222: Metformin enhances cisplatin cytotoxicity of lung cancer through Stat3 pathway Cancer Research
06/04/2012
Abstract 3221: Anticancer effect of PUFAs is mediated by inhibition of polyisoprenylated methylated protein methyl esterase Cancer Research
06/04/2012
Abstract 3219: Changing the metabolism of cancer cells with PKM2 activators - a path to a cancer metabolism drug Cancer Research
06/04/2012
Abstract 3217: Mechanistic analysis of the ketogenic diet versus KetoCal(R) as adjuvant treatments for malignant glioma Cancer Research
06/04/2012
Abstract 3216: Cytosolic leucine metabolism regulates the expression of prometastatic proteins: The genesis of a new druggable target Cancer Research
06/04/2012
Abstract 3215: Metabolic alterations of cancer cell as potential anti-cancer target Cancer Research
06/04/2012
Abstract 3214: Resveratrol potentiates glycolytic inhibitor-induced neuroblastoma cell death independent of sirt activity Cancer Research
06/04/2012
Abstract 3213: Selective killing of advanced prostate cancer cells by targeting the Warburg effect and autophagy Cancer Research
06/04/2012
Abstract 3212: N-acetylcysteine protects melanoma cells from glucose depletion through unequal modulation of SOD1 and Copper chaperone for SOD1 depending on p53 mutational status Cancer Research
06/04/2012
Abstract 3211: Inhibition of Hsp90 impairs expression of VDAC in plasma and mitochondrial membrane influencing cancer cell metabolism Cancer Research
06/04/2012
Abstract 3210: Glutamine synthetase is a genetic determinant of cell-type specific glutamine independence in breast epithelia Cancer Research
06/04/2012
Abstract 3209: Metformin suppresses the growth and modulates the metabolic profiles of pancreatic cancer cells under hypoxia in an IKK{alpha}-dependent manner Cancer Research
06/04/2012
Abstract 3206: Three-dimensional hyaluronan hydrogel culture systems facilitate study of the complex microenvironment of bone metastatic prostate cancer cells Cancer Research
06/04/2012
Abstract 3205: Isolating RNA, DNA and protein from the same sample allows correlation of multiple biomarkers Cancer Research
06/04/2012
Abstract 3204: Novel, rapid and sensitive technology to analyze gene expression directly from archived FFPE clinical oncology specimens without sample preparation Cancer Research
06/04/2012
Abstract 3203: High quality DNA obtained with an automated DNA Extraction method with 15 to 40 year old formalin fixed paraffin embedded (FFPE) blocks from normal and cancer tissues Cancer Research
06/04/2012
Abstract 3202: Universal detection of protein phosphorylation based on multi-functionalized soluble nanopolymers Cancer Research
06/04/2012
Abstract 3201: Generation of tumor-antigen specific T cells under highly controlled environmental conditions by utilization of a novel cGMP compliant cell culture reactor Cancer Research
06/04/2012
Abstract 3200: The AKT inhibitor AZD5363 is selectively active in PIK3CA mutant gastric cancer cell lines, and sensitizes a gastric cancer explant model to docetaxel Cancer Research
06/04/2012
Abstract 3199: Miniaturized, multiplexed, highly sensitive protein NanoArray assay for measuring biomarkers in dried blood spot (DBS) samples Cancer Research
06/04/2012
Abstract 3198: The CEE-Selector Assay: A tool for the identification of rare allele variants Cancer Research
06/04/2012
Abstract 3197: Functional microscale cell-based systems for studying hematologic cancers in complex microenvironments Cancer Research
06/04/2012
Abstract 3196: In vivo drug sensitivity testing of CTCs isolated using the FMSA device Cancer Research
06/04/2012
Abstract 3195: Formalin-fixed and paraffin-embedded (FFPE) DNA recovery for high-throughput genotyping of lung cancer tissues Cancer Research
06/04/2012
Abstract 3194: Reverse engineering the interplay between multiple myeloma and microenvironment Cancer Research
06/04/2012
Abstract 3192: Translational research platform (SnapPath™) for enabling drug development and personalized medicine in metastatic melanoma Cancer Research
06/04/2012
Abstract 3191: Primary human tumor-derived Oncoprint platform predicts molecular mechanism of sensitivity and resistance to anti-EGFR in colorectal cancer: A step towards personalized cancer medicine Cancer Research
06/04/2012
Abstract 3189: Preservation of immunorecognition by the transfer of cells from 10% neutral buffered formalin to 70% ethanol Cancer Research
06/04/2012
Abstract 3188: Development of a cancer pharmacopeia-wide ex-vivo drug sensitivity and resistance testing (DSRT) platform for AML: Towards individually optimized therapy and improved understanding of drug resistance patterns Cancer Research
06/04/2012
Abstract 3187: Ex vivo characterization of CTCs isolated using the FMSA device Cancer Research
06/04/2012
Abstract 3186: Comparative analysis of different total RNA sequencing approaches Cancer Research
06/04/2012
Abstract 3185: Rapid and efficient methods for preparing rRNA-depleted and directional RNA-Seq libraries from low-input and FFPE RNA samples Cancer Research
06/04/2012
Abstract 3184: Whole genome sequencing of low-input fresh frozen prostate cancer biopsies Cancer Research
06/04/2012
Abstract 3183: Breast Cancer MethylSeq: Analysis of bisulfite converted breast cancer genomes using microdroplet-based targeted sequencing Cancer Research
06/04/2012
Abstract 3182: Single tube, ultra-multiplexed PCR with Ion AmpliSeq™ technology for amplicon resequencing on the Ion Personal Genome Machine™ System Cancer Research
06/04/2012
Abstract 3180: A fast solution to NGS library preparation with low nanogram DNA input Cancer Research
06/04/2012
Abstract 3179: Targeted re-sequencing of cancer-related genes from matched FFPE and fresh-frozen tumor samples using the Illumina sequencing platform Cancer Research
06/04/2012
Abstract 3178: Can DNA from archived formalin-fixed paraffin embedded (FFPE) cancer tissues be used for somatic mutation analysis in next generation sequencing Cancer Research
06/04/2012
Abstract 3176: miR-211 promotes the progression of head and neck carcinomas by targeting TGF{beta}RII Cancer Research
06/04/2012
Abstract 3174: Genome-wide analysis of epigenetically silenced miRNAs reveals miR-340 as a methylation repressed potential tumour suppressor miRNA in neuroblastoma Cancer Research
06/04/2012
Abstract 3173: Identification of miR-4423 as a primate-specific microRNA highly expressed in airway epithelium and associated with lung cancer Cancer Research
06/04/2012
Abstract 3172: Role of miRNA-211in melanocytes and melanoma Cancer Research
06/04/2012
Abstract 3171: Hyperactive MAPK dysregulation of microRNAs contributes to the ER-negative phenotype in breast cancer Cancer Research
06/04/2012
Abstract 3170: Comprehensive analysis of the microRNA-128 function in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 3169: MicroRNA-144 induces proliferation and invasion in nasopharyngeal carcinoma through repression of PTEN Cancer Research
06/04/2012
Abstract 3168: Functional analysis and target identification of specific miRNAs involved in development of metastases in renal cell carcinoma Cancer Research
06/04/2012
Abstract 3166: Molecular target regulated by tumor suppressive microRNA-1 and microRNA-133a in prostate cancer Cancer Research
06/04/2012
Abstract 3165: microRNA-148a: A novel oncogenic microRNA in glioblastoma Cancer Research
06/04/2012
Abstract 3163: Exploration of microRNA-34a effects in human glioma cell lines Cancer Research
06/04/2012
Abstract 3162: Characterizing premalignant progression within optically altered oral mucosa fields using microRNA expression profiles Cancer Research
06/04/2012
Abstract 3161: Identification of HPV/p16-associated microRNAs in primary oropharyngeal carcinoma Cancer Research
06/04/2012
Abstract 3160: Expression of apoptosis-regulating miRNAs and target mRNAs in oral squamous cell carcinoma Cancer Research
06/04/2012
Abstract 3158: MicroRNA signatures associate with pathogenesis and progression of osteosarcoma Cancer Research
06/04/2012
Abstract 3157: Clinical relevance of miR-200 family members in various cancers Cancer Research
06/04/2012
Abstract 3156: MicroRNA profiling for the detection of melanoma Cancer Research
06/04/2012
Abstract 3155: High-throughput profiling of miRNA expression in plasma and cerebrospinal fluid using OpenArray(R) platform for biomarker discovery Cancer Research
06/04/2012
Abstract 3154: Sequencing of the small RNA transcriptome in cytologically normal bronchial airway epithelium of smokers with and without lung cancer Cancer Research
06/04/2012
Abstract 3153: H. pylori infection enhances the degradation of Drosha through regulating its acetylation-ubiquitination switches Cancer Research
06/04/2012
Abstract 3152: Molecular networks regulated by tumor suppressive microRNA-1 and microRNA-133a in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 3151: Molecular and clinicopathological impact of miR-375 deregulation in prostate cancer Cancer Research
06/04/2012
Abstract 3150: miR-100 in ovarian cancer cell lines Cancer Research
06/04/2012
Abstract 3149: MicroRNA-141 inhibits proliferation and invasion by suppressing the Wnt signaling pathway in renal cell carcinoma Cancer Research
06/04/2012
Abstract 3148A: MYOD1, hTERT, and RASSF1A gene promoter methylation is useful for prediction of outcome/ prognostication in patients with invasive cervical cancer Cancer Research
06/04/2012
Abstract 3148: Frequent epigenetic inactivation of keap1 gene in non small cell lung cancer Cancer Research
06/04/2012
Abstract 3147: Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers Cancer Research
06/04/2012
Abstract 3146: Awake the sleeping: Gene specific re-expression of epigenetically silenced candidate tumor suppressor genes in cervical cancer by artificial transcription factors Cancer Research
06/04/2012
Abstract 3144: A role for DOK2 methylation in platinum resistance and tumor suppression in ovarian cancer Cancer Research
06/04/2012
Abstract 3143: Epigenetic regulation of PTEN by miR-185 and miR-200b in liver cancer Cancer Research
06/04/2012
Abstract 3142: Hypermethylation of the tissue inhibitor of metalloproteinases-2 gene in multiple myeloma Cancer Research
06/04/2012
Abstract 3140: Constitutive and regulated expression of GPR109A by DNA methylation and IFN-{gamma} in human colon carcinoma cells Cancer Research
06/04/2012
Abstract 3139: Frequent downregulation of NGB/GTPBP in lung cancer Cancer Research
06/04/2012
Abstract 3138: Epigenetic regulation of Src pathway in pancreatic adenocarcinomas Cancer Research
06/04/2012
Abstract 3137: Epigenetic regulators influencing dual histone reader TRIM24 in estrogen receptor-mediated transcription in breast cancer Cancer Research
06/04/2012
Abstract 3136: C-Myc-mediated transcriptional repression of HPP1 in colon cancer by recruitment of HDACs Cancer Research
06/04/2012
Abstract 3135: Epigenetic regulation of miR-1275 through histone H3 lysine 27 trimethylation during human glioma stem-like cell differentiation Cancer Research
06/04/2012
Abstract 3303: Clonal evolution of pre-leukemic hematopoietic stem cells precedes human acute myeloid leukemia Cancer Research
06/04/2012
Abstract 3301: Multiple cytokeratin-19 positive stem cells contribute to the clonal origin of colonic tumors in mice Cancer Research
06/04/2012
Abstract 3299: Hematopoietic chimerism in liver transplantation patients and hematopoietic stem/progenitor cells in adult human liver Cancer Research
06/04/2012
Abstract 3298: Arsenic induces human bronchial epithelial cell transformation featured with tumor-initiating cells Cancer Research
06/04/2012
Abstract 3297: A cell of origin for cervical cancer Cancer Research
06/04/2012
Abstract 3296: SRC-3 is a critical mediator in the development of castration-resistant prostate cancer Cancer Research
06/04/2012
Abstract 3295: Systematic in vivo analysis of PI3K pathway aberrations in a mouse model for invasive lobular carcinoma Cancer Research
06/04/2012
Abstract 3294: A novel, inducible, mammary gland-specific PELP1 murine breast cancer model Cancer Research
06/04/2012
Abstract 3293: p53 suppresses type II endometrial carcinomas in mice and governs endometrial tumour aggressiveness in humans Cancer Research
06/04/2012
Abstract 3292: A genetically engineered mouse model for high grade serous "ovarian" carcinoma arising in the fallopian tube Cancer Research
06/04/2012
Abstract 3291: Defining the role of the cellular polarity regulator Scrib in epithelial tumorigenesis Cancer Research
06/04/2012
Abstract 2932: Knockdown of polypyrimidine tract-binding protein (PTB) sensitizes ovarian cancer cells to chemotherapeutic agents in vitro Cancer Research
06/04/2012
Abstract 2931: Inherited variation at chromosome 12p13.33 including RAD52 influences squamous cell lung carcinoma risk Cancer Research
06/04/2012
Abstract 2929: Predictors of survival in never-smokers with non-small cell lung cancer: A large-scale, two-phase genetic study Cancer Research
06/04/2012
Abstract 2928: Functional effects of SNPs in non-coding RNAs at the 3q25 ovarian cancer susceptibility locus Cancer Research
06/04/2012
Abstract 2927: MicroRNA binding site polymorphisms influence ovarian cancer risk in the collaborative oncological gene-environment study Cancer Research
06/04/2012
Abstract 2926: Effect of common cancer susceptibility variants on risk of second primary cancers: results from the Multiethnic Cohort and PAGE studies Cancer Research
06/04/2012
Abstract 2925: Genome-wide association study identifies 10q24.32 variants associated with arsenic metabolism and premalignant skin lesion risk in Bangladesh Cancer Research
06/04/2012
Abstract 2924: Constitutively active androgen receptor splice variants function independently of full-length androgen receptor in a cell-based model of castrate-resistant prostate cancer Cancer Research
06/04/2012
Abstract 2921: Critical mediation of E2-induced apoptosis through c-Src in long-term estrogen deprived breast cancer cells Cancer Research
06/04/2012
Abstract 2920: Transcriptional regulation of estrogen response through long-range chromatin interactions Cancer Research
06/04/2012
Abstract 2919: Effect of selumetinib and AZD8055 on the growth of anastrozole resistant tumors Cancer Research
06/04/2012
Abstract 2918: Estrogen receptor coactivator MED1 in mammary progenitor/stem cell determination and tamoxifen resistance of breast cancer Cancer Research
06/04/2012
Abstract 2917: Design, synthesis and biological evaluation of two chemical classes as novel small molecule Mcl-1 inhibitors Cancer Research
06/04/2012
Abstract 2916: Discovery of pyrazolimidazopyridine compounds as potent in vitro and in vivo anaplastic lymphoma kinase inhibitors Cancer Research
06/04/2012
Abstract 2915: Discovery and characterization of OSI-296, a dual inhibitor of cMET and RON kinases Cancer Research
06/04/2012
Abstract 2914: Creation of a novel biochemical and biophysical assay suite to enable the identification of inhibitors targeting inactive kinases Cancer Research
06/04/2012
Abstract 2913: Identification of GSK2636771, a potent and selective, orally bioavailable inhibitor of phosphatidylinositol 3-kinase-beta (PI3K{alpha}) for the treatment of PTEN deficient tumors Cancer Research
06/04/2012
Abstract 2912: Development of potent SHP2 inhibitors for in vivo studies Cancer Research
06/04/2012
Abstract 2911: SAR125844: a potent and selective ATP-competitive inhibitor of MET kinase Cancer Research
06/04/2012
Abstract 2910: Selenium nanoparticles suppress prostate LNCaP cancer cells growth through induced endogenous apoptosis Cancer Research
06/04/2012
Abstract 2909: Doxorubicin-loaded zirconium phosphate nanoparticles for intracellular anticancer drug delivery to breast cancer cells Cancer Research
06/04/2012
Abstract 2908: Biological evaluation of paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery Cancer Research
06/04/2012
Abstract 2907: Novel liposomal compositions of PharmaGap's lead peptide: Effect on ovarian cancer cell proliferation and signaling pathways Cancer Research
06/04/2012
Abstract 2904: EGFR-targeted gold liposome for molecular imaging and therapy on NSCLC cells Cancer Research
06/04/2012
Abstract 2903: Therapeutic targeting of leukemia and lymphoma with a neuropilin-1 binding pro-apoptotic peptide Cancer Research
06/04/2012
Abstract 2901: Development of mannose-polyethyleneglycol-modified liposomes for idiopathic thrombocytopenic purpura Cancer Research
06/04/2012
Abstract 2900: Redox nanoparticle enhances effect of anticancer chemotherapy and suppresses cardio-toxicity Cancer Research
06/04/2012
Abstract 2898: Intracellular dissociation of polymer coating from nanoparticles Cancer Research
06/04/2012
Abstract 2897: Preferential drug delivery to cancer cells than to normal cells by using the Niosome-Chitosan Thermo-responsive Double Package System (NCTR-DPS) Cancer Research
06/04/2012
Abstract 2896: Nanoparticle co-delivery of RNAi and chemotherapy for the treatment of drug-resistant cancers Cancer Research
06/04/2012
Abstract 2894: Environmentally responsive nanoparticles for the intracellular delivery of RNAi therapeutics into tumor-associated macrophages Cancer Research
06/04/2012
Abstract 2893: Curcumin loaded magnetic nanoparticles for breast cancer therapeutics and imaging applications Cancer Research
06/04/2012
Abstract 2892: Enhancing anti cancer activity of PI103, a dual PI3K/mTOR inhibitor, by designing a self assembled Nanoformulation Cancer Research
06/04/2012
Abstract 2891: Photodynamic therapy using PMB polymer as a new nanotransporter of verteporfin for the treatment of lymph node metastasis in breast cancer Cancer Research
06/04/2012
Abstract 2889: Development of a novel nanoconstruct for tumor hypoxia photothermal therapy Cancer Research
06/04/2012
Abstract 2888: Lipid nanoparticle-mediated delivery of siRNA to extrahepatic tumors Cancer Research
06/04/2012
Abstract 2887: Nanoconstructs for the efficient delivery of siRNA molecules against Aquaporin-1 for anti-angiogenic therapies Cancer Research
06/04/2012
Abstract 2886: Carbon nanotube-mediated siRNA for gastrin-releasing peptide receptor silencing in neuroblastoma Cancer Research
06/04/2012
Abstract 2885: Urokinase plasminogen activator system targeted delivery of arsenic trioxide loaded nanobins as a novel ovarian cancer therapeutic Cancer Research
06/04/2012
Abstract 2884: Preclinical studies on tumor retention, antitumor efficacy and toxicity of thermally responsive polypeptide-based radionuclide intratumoral depot in nude mice Cancer Research
06/04/2012
Abstract 2882: Therapeutic effects of ormeloxifene on cervical cancer Cancer Research
06/04/2012
Abstract 2881: Cytotoxic effect of trastuzumab on macrophage-infiltrated human mammary tumor spheroids Cancer Research
06/04/2012
Abstract 2880: Dasatinib induces apoptosis in head and neck squamous cell carcinoma cells through down-regulation of epidermal growth factor receptor (EGFR) in vitro and in vivo Cancer Research
06/04/2012
Abstract 2879: Pre-clinical characterization of Dacomitinib, an irreversible pan-HER inhibitor, combined with radiation therapy in head and neck cancer models Cancer Research
06/04/2012
Abstract 2878: Anticancer effects of c-Met inhibitors in esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2877: Perifosine alone and in combination with antimetabolites interferes with NF-kB pathway activation in colon cancer cell lines Cancer Research
06/04/2012
Abstract 2876: Farnesyltransferase inhibitor induces p53-dependent cellular senescence in colon cancer cells Cancer Research
06/04/2012
Abstract 2875: Meta-iodo-benzylguanidine (MIBG) is a MYCN/MYC destabilizer that specifically targets neural crest derived tumors Cancer Research
06/04/2012
Abstract 2873: Opposing effects of NF-{kappa}B inhibition during chemical lung carcinogenesis Cancer Research
06/04/2012
Abstract 2872: Functional inhibition of HSP90 potentiates the effects of ionizing radiation in colorectal cancer Cancer Research
06/04/2012
Abstract 2871: Inhibition of androgen receptor-mediated expression of prostate derived ets transcription factor (PDEF) induces a loss of prostate cancer cell differentiation Cancer Research
06/04/2012
Abstract 2870: p28, a cell penetrating peptide fragment of azurin, inhibits COP1 mediated ubiquitination of wild type and mutated p53, but does not alter intracellular levels of c-jun Cancer Research
06/04/2012
Abstract 2869: p53 response of cancer associated fibroblasts (CAFs) to cisplatin is closely correlated with the p53 response of tumor cells in lung cancer tissue cultures Cancer Research
06/04/2012
Abstract 2868: Pancreatic tumor stromal cells express high levels of {alpha}-glutamyl transferase that may be employed to deliver a metabolism inhibitor to the tumor mass Cancer Research
06/04/2012
Abstract 2867: A novel WT1-derived peptide induces cellular senescence and inhibits tumor growth in a human melanoma cell line and xenograft model Cancer Research
06/04/2012
Abstract 2866: Exploring the basis for platinum and ionizing radiation combination with R1507 (an anti-IGF1R monoclonal antibody) in a small cell lung cancer (SCLC) model using integrated functional and genomic approaches on both short- and long-term drug exposure reveals adaptive mechanisms Cancer Research
06/04/2012
Abstract 2865: Gemcitabine causes telomere shortening by stabilizing TRF2 Cancer Research
06/04/2012
Abstract 2863: Development of an AKT1-specific synbody that inhibits MOLT-4 cell growth Cancer Research
06/04/2012
Abstract 2862: Deregulated GSK3{beta} sustains gastrointestinal cancer cells by modulating hTERT and telomerase Cancer Research
06/04/2012
Abstract 2861: Inhibition of mTOR and AKT as a potential strategy for the treatment of basal-like breast cancer Cancer Research
06/04/2012
Abstract 2860: EphA2 and its phosphorylation is a key determinant of dasatinib sensitivity in endometrial cancer Cancer Research
06/04/2012
Abstract 2859: Dual targeting of protein tyrosine kinase c-Src and protein tyrosine phosphatase SHP-2 is a novel therapeutic strategy that induces potent inhibition of pancreatic cancer cell viability in vitro and tumor progression in vivo Cancer Research
06/04/2012
Abstract 2858: Mirk/dyrk1B kinase inhibition increases ROS and apoptosis in ovarian cancer cells, but has little effect on normal diploid cells Cancer Research
06/04/2012
Abstract 2857: Induced expression of DUSP4 and PPM1A in ER-negative breast cancer cells suppresses proliferation and invasion Cancer Research
06/04/2012
Abstract 2856: Functional profile of BEZ-235 activity in human tumor primary culture microspheroids by ex vivo analysis of programmed cell death (EVA/PCD) Cancer Research
06/04/2012
Abstract 2855: SRC represents a potential therapeutic target in liposarcoma Cancer Research
06/04/2012
Abstract 2853: Discovery of phosphatases that regulate growth and tumorigenicity of ER-negative breast cancers Cancer Research
06/04/2012
Abstract 2852: Combination therapy: Galectin-3C and bortezomib potent anticancer activity and inhibition of angiogenesis, chemotaxis, and NF-kB activation in human multiple myeloma Cancer Research
06/04/2012
Abstract 2851: Cabozantinib (XL184) inhibits prostate tumor growth and bone lesion development Cancer Research
06/04/2012
Abstract 2850: Demonstration of anti-tumor efficacy in multiple preclinical cancer models using a novel peptide inhibitor (Aurigene-012) of the PD1 signaling pathway Cancer Research
06/04/2012
Abstract 2849: Optimization and pharmacokinetic characterization of potent CXCR4 antagonist CovX-Bodies Cancer Research
06/04/2012
Abstract 2848: Preclinical activity of OM-RCA-01, a humanized anti-FGFR1 antibody, in renal cell carcinoma (RCC) Cancer Research
06/04/2012
Abstract 2847: PECAM-1 targeting extends overall survival in various advanced metastatic mouse tumor models Cancer Research
06/04/2012
Abstract 2846: Exploring ERBB3 as novel drug target in lung cancer Cancer Research
06/04/2012
Abstract 2845: Prostaglandin E receptor EP4 antagonist RQ00015986 inhibits breast cancer metastasis and protects natural killer cells from PGE-mediated immune suppression Cancer Research
06/04/2012
Abstract 2844: Inhibiting androgen receptor and JunD protein interaction to prevent prostate cancer progression Cancer Research
06/04/2012
Abstract 2843: A quantitative sequencing based method for the monitoring of clonal expansion Cancer Research
06/04/2012
Abstract 2842: Development of a novel TrkA HTS assay using template directed self assembly (TDA) Cancer Research
06/04/2012
Abstract 2841: A simplified approach to measuring thymidine kinase activity in cells, tumors, and blood as a biomarker of tumor proliferative potential Cancer Research
06/04/2012
Abstract 2840: Development of a bioluminescent cell-based bioassay to measure Fc receptor functionality in antibody-dependent cellular cytotoxicity Cancer Research
06/04/2012
Abstract 2839: Antitumor activity on colorectal and pancreatic tumors of a new strategy based on ROS generation by non-thermal plasma Cancer Research
06/04/2012
Abstract 2838: High-throughput genotoxicity screening unlocks chemotherapeutic potential of antioxidants Cancer Research
06/04/2012
Abstract 2837: Assay development for the discovery of semaphorin 3B-inducing agents from natural product sources Cancer Research
06/04/2012
Abstract 2836: Downregulation of galectin-1 by OTX-008, a novel calyx[4]arene, is associated with galectin-1 oxidation followed by proteosomal degradation in human head and neck tumor cell lines Cancer Research
06/04/2012
Abstract 2835: Discovery of novel inhibitors for ECT2 as a novel therapeutic strategy for lung cancer Cancer Research
06/04/2012
Abstract 2834: Discovery of a novel class of prostaglandin e2 synthesis inhibitors with anti-tumor activity in colorectal cancer Cancer Research
06/04/2012
Abstract 2833: The protein ps20 increases tumourigenic potential in prostate cancer epithelial cells Cancer Research
06/04/2012
Abstract 2832: Fibroblast growth factors in head and neck cancer: Genetic alterations and therapeutic targeting with ponatinib Cancer Research
06/04/2012
Abstract 2831: Studies on the mechanistic basis of the anticancer activity of 2,4-disulfonyl-PBN (OKN-007) Cancer Research
06/04/2012
Abstract 2830: Multikinase inhibition by TG02 is therapeutically effective in two forms of breast cancer Cancer Research
06/04/2012
Abstract 2829: Activity of EP-100 in Non-Hodgkin's Lymphoma - synergy in combination Cancer Research
06/04/2012
Abstract 2827: In vivo effects of ICA-1 on breast cancer and glioma xenografts Cancer Research
06/04/2012
Abstract 2826: Preclinical development of a Pim kinase inhibitor for cancer treatment Cancer Research
06/04/2012
Abstract 2825: Regorafenib and Sorafenib induce reversible quiescence in human hepatoma cells Cancer Research
06/04/2012
Abstract 2824: Therapeutic potential of multi-kinase inhibitor sorafenib in osteosarcoma cells Cancer Research
06/04/2012
Abstract 2823: PHA-739358, a pan-Aurora kinase inhibitor, induces apoptosis and inhibits invasion in melanoma cell lines Cancer Research
06/04/2012
Abstract 2822: Characterization of the effects of PLX4720 in the immunocompetent BRAF/PTEN mouse melanoma model Cancer Research
06/04/2012
Abstract 2820: Vorinostat abrogates ridaforolimus-induced activation of Akt in synovial sarcoma cells: A possible rationale for their synergism Cancer Research
06/04/2012
Abstract 2819: Temsirolimus inhibits colon cancer growth in vitro and in vivo Cancer Research
06/04/2012
Abstract 2818: Aurora B kinase inhibitor barasertib (AZD1152) and cytarabine in combination exert more than additive cytotoxicities against cytarabine-resistant acute myeloid leukemia cells in vitro Cancer Research
06/04/2012
Abstract 2817: Preclinical studies of the PI3K/mTOR dual inhibitors in endometrial cancer cell lines Cancer Research
06/04/2012
Abstract 2815: Sylvestrol inhibits protein synthesis by downregulating the AKT/mTOR pathway Cancer Research
06/04/2012
Abstract 2814: Potent and selective small molecule inhibitors of polo-like kinase 1: Biological characterization Cancer Research
06/04/2012
Abstract 2813: Modulation of Signal Transducer and Activator of Transcription 3 by emodin through the induction of a phosphatase leads to the suppression of HCC growth in orthotopic mouse model Cancer Research
06/04/2012
Abstract 2812: mTOR kinase mediates dissemination and colonization of breast cancer metastasis Cancer Research
06/04/2012
Abstract 2811: Preclinical evaluation of combined TKI258 and RAD001 in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 2809: BMS-777607, a small molecule RON/MET kinase inhibitor induces polyploidy in breast cancer cells: molecular mechanism and therapeutic implication Cancer Research
06/04/2012
Abstract 2808: Mechanism of action of the multikinase inhibitor TG02 in chronic lymphocytic leukemia Cancer Research
06/04/2012
Abstract 2807: Inhibition of mixed lineage kinase activity results in G2/M arrest and apoptosis in ER-positive breast cancer cells Cancer Research
06/04/2012
Abstract 2806: BRAF and MEK inhibitor profiling across 240 tumor cell lines to correlate with sensitivity and resistant biomarkers Cancer Research
06/04/2012
Abstract 2805: In vitro characterization of AMG 511, a potent and selective class I PI3K inhibitor for the treatment of cancer Cancer Research
06/04/2012
Abstract 2804: Radiosensitization by the Dual PI3K/mTOR inhibitor NVP-BEZ235 Cancer Research
06/04/2012
Abstract 2803: GSK3 plays a crucial role in determining cell response to mTOR inhibitors Cancer Research
06/04/2012
Abstract 2802: Selective inhibition of signal transducers and activators of transcription 3 overexpressing endometrial cancer cells, using HO-3867, a novel STAT3 inhibitor Cancer Research
06/04/2012
Abstract 2800: Dual PI3K/mTOR inhibitor NVP BEZ-235 suppresses translation of hypoxia-inducible factor (HIF)-1{alpha} and increases cell death under hypoxia Cancer Research
06/04/2012
Abstract 2799: BAY 1082439, a highly selective and balanced PI3K{alpha}/{beta} inhibitor demonstrated potent activity in tumors with activated PI3K{alpha} and loss-of-function of PTEN Cancer Research
06/04/2012
Abstract 2798: Cytotoxic and cystostatic properties of rapamycin are due to differential effects on the phosphorylation of mTORC1 substrates S6 kinase and 4E-BP1 Cancer Research
06/04/2012
Abstract 2797: AMG 511, a potent and selective class I PI3K inhibitor, demonstrates anti-tumor activity in multiple xenograft models Cancer Research
06/04/2012
Abstract 2796: Efficacy and biomarker modulation by AZD1208, a novel, potent and selective pan-Pim kinase inhibitor, in models of acute myeloid leukemia Cancer Research
06/04/2012
Abstract 2795: Safety profile and therapeutic potential in breast cancer of STX140, an original tubulin binding agent Cancer Research
06/04/2012
Abstract 3104: Genome-wide screen for modulators of cell death induced by the NEDD8-activating enzyme inhibitor MLN4924 Cancer Research
06/04/2012
Abstract 3103: Differences in the DDR enzymes activation kinetics between normal and cancer cells could be utilized to achieve targeted cellular sensitivity towards genotoxic agents Cancer Research
06/04/2012
Abstract 3102: Hexavalent chromium induces chromosome instability leading to DNA double strand break repair deficiency and neoplastic transformation Cancer Research
06/04/2012
Abstract 3101: Transition from extrachromosomal to intrachromosomal amplification in glioblastoma cells Cancer Research
06/04/2012
Abstract 3100: Identifying novel chromosomal fusions out of RNAseq data from oropharyngeal cancers Cancer Research
06/04/2012
Abstract 3099: Gastroesophageal junction adenocarcinoma displays abnormalities in homology directed repair Cancer Research
06/04/2012
Abstract 3096: ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis in mice: Linkage to resistance to apoptosis and susceptibility to genomic instability Cancer Research
06/04/2012
Abstract 3095: The host cell reactivation (HCR) assay for measuring DNA repair capacity (DRC) in cancer research after 20 years; re-evaluation and lessons learned Cancer Research
06/04/2012
Abstract 3093: Elucidation of c-KIT- dependent signaling to MITF Cancer Research
06/04/2012
Abstract 3091: A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis Cancer Research
06/04/2012
Abstract 3090: Oncogenic ETS transcription factors bind ETS/AP-1 sequences and activate a RAS/MAPK gene expression program in the absence of MAPK activation Cancer Research
06/04/2012
Abstract 3088: Essential roles of ATM in GM-CSF-induced bone marrow differentiation to dendritic cells Cancer Research
06/04/2012
Abstract 3086: {alpha}-arrestin-1 acts as a nuclear transcriptional regulator of endothelin A receptor signalling to promote ovarian cancer progression Cancer Research
06/04/2012
Abstract 3085: ER{alpha} phosphorylation on Ser167 in the development of endometrial cancer Cancer Research
06/04/2012
Abstract 3084: Constitutively active RAS signaling reduces 1,25 dihydroxyvitamin D-mediated gene transcription by suppressing vitamin D receptor gene expression in mouse colon epithelial cells Cancer Research
06/04/2012
Abstract 3083: Dual-specificity phosphatase-2 (DUSP2) negatively control cyclooxygenase-2 (COX-2) expression in cancer cells Cancer Research
06/04/2012
Abstract 3082: TGF-{beta} synergistically stimulates malignant mesothelioma growth with defects in the Hippo pathway by inducing CTGF expression Cancer Research
06/04/2012
Abstract 3081: Crosstalk between Runx2 regulatory network and PI3K/Akt signaling pathway in breast cancer cells Cancer Research
06/04/2012
Abstract 3080: MYC antagonizes imatinib-induced differentiation in chronic myeloid leukemia cells through downregulation of p27KIP1 Cancer Research
06/04/2012
Abstract 3079: Akt interacts and phosphorylates PHF20, a transcription factor binding to and inducing p53 Cancer Research
06/04/2012
Abstract 3078: Effects of neuregulins in the regulation of EGFR in breast cancer cell lines Cancer Research
06/04/2012
Abstract 3077: Nek3/Vav2 modulation of the expression of genes involved in breast cancer pathogenesis Cancer Research
06/04/2012
Abstract 3075: NOTCH1 dimerization directly activates Rag1 and Rag2 in murine T-cell leukemia Cancer Research
06/04/2012
Abstract 3074: NAD(P)H:quinone oxidoreductase 1 stabilizes C/EBP{alpha} from 20S proteasomal degradation leading to protection against myeloproliferative disease Cancer Research
06/04/2012
Abstract 3073: EphrinA1 inhibits non small cell lung cancer (NSCLC) tumor growth via induction of miRNA-122 Cancer Research
06/04/2012
Abstract 3072: HER2 signaling affects SRC-3 phosphorylation and gene regulatory potential within the cistrome Cancer Research
06/04/2012
Abstract 3071: Obesity-associated growth factor signaling upregulates aromatase expression and estrogen receptor activity in breast cancer cells Cancer Research
06/04/2012
Abstract 3070: Activated EGFR and PPAR{delta} regulate MUC1 expression in human uterine and pancreatic cancer cell lines Cancer Research
06/04/2012
Abstract 3068: Hedgehog signaling regulates drug sensitivity by targeting ABC transporters in epithelial ovarian cancer (EOC) Cancer Research
06/04/2012
Abstract 3067: Regulation of PAX2 expression/activity by hypoxia and EGF in breast cancer cells Cancer Research
06/04/2012
Abstract 3065: Interferon consensus sequence-binding protein (ICSBP) regulates the transforming growth factor-beta type I receptor expression in osteosarcoma cells Cancer Research
06/04/2012
Abstract 3064: An alternative mechanism of action for paclitaxel in breast cancer Cancer Research
06/04/2012
Abstract 3063: Mcl-1 dependency is a predictive biomarker for apoptotic induction by short-term dinaciclib (SCH 727965) treatment Cancer Research
06/04/2012
Abstract 3062: Ada3, a component of STAGA HAT complex, controls cell cycle by regulating c-myc Cancer Research
06/04/2012
Abstract 3060: DYRK2-mediated phosphorylation of c-Jun and c-Myc is requisite for proper control of the G1/S transition Cancer Research
06/04/2012
Abstract 3058: Mad1 Serine-214 phosphorylation is essential for the spindle assembly checkpoint Cancer Research
06/04/2012
Abstract 3057: CDK5 modulates the cell cycle, apoptosis and paclitaxel sensitivity in human ovarian cancer cells with wild-type p53 function Cancer Research
06/04/2012
Abstract 3056: High levels of Wee1 are associated with malignancy and has potential as a therapeutic target in malignant melanoma Cancer Research
06/04/2012
Abstract 3054: P1446A-05: a new oral cyclin-dependent kinase inhibitor with potent preclinical antitumor activity Cancer Research
06/04/2012
Abstract 3053: Identification of a novel cytoplasmic role for MTDH/AEG-1 in chemoresistance as a RNA binding protein Cancer Research
06/04/2012
Abstract 3052: Role of p53 in cdk inhibitor VMY-1-103-induced apoptosis in prostate cancer Cancer Research
06/04/2012
Abstract 3051: CDC28 protein kinase subunit 1B (CKS1B) is a potential therapeutic target in esophageal adenocarcinomas overexpressing the CDK inhibitor p21Cip1/Waf1 Cancer Research
06/04/2012
Abstract 3050: Inducing apoptosis in mantle cell lymphoma using inhibitors of cyclin-dependent kinases and the Bcl-2 inhibitor ABT-737 Cancer Research
06/04/2012
Abstract 3047: MK1775, a selective Wee1 inhibitor shows antitumor activity against sarcoma cells Cancer Research
06/04/2012
Abstract 3046: Cathepsin B and uPAR downregulation sensitizes glioma initiating cells to radiation induced cell cycle arrest Cancer Research
06/04/2012
Abstract 3045: Sesamin synergistically potentiates the anticancer effects of {gamma}-tocotrienol in mammary tumor cells Cancer Research
06/04/2012
Abstract 3044: A new paradigm for ABCB6: Role in growth and proliferation Cancer Research
06/04/2012
Abstract 3043: A CDK-independent function of p27kip1 controls cell proliferation Cancer Research
06/04/2012
Abstract 3042: Glypican-1 (GPC1) promotes S-phase entry and DNA replication in human glioma cells Cancer Research
06/04/2012
Abstract 3041: Macrophage inhibitory cytokine-1 stimulates proliferation of human umbilical vein endothelial cells by up-regulating Cyclins D1 and E through the PI3K/Akt- and ERK-dependent AP-1 and E2F activation signaling pathways Cancer Research
06/04/2012
Abstract 3040: Terbinafine inhibits oral squamous cell carcinoma growth through anti-cancer cell proliferation and anti-angiogenesis Cancer Research
06/04/2012
Abstract 3039: The high mobility group A1 oncogene & NF-{kappa}B cooperate in malignant transformation Cancer Research
06/04/2012
Abstract 3038: Delineating the role of Arid3B in normal and malignant differentiation of esophageal and cervical stratified squamous epithelia Cancer Research
06/04/2012
Abstract 3037: Cyr61/CCN1 regulates SHh through Notch signaling in pancreatic cancer cells Cancer Research
06/04/2012
Abstract 3036: Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer Cancer Research
06/04/2012
Abstract 3035: Bone morphogenetic proteins signal through Smad2 and Smad3 to regulate cell migration and proliferation Cancer Research
06/04/2012
Abstract 3032: Role of ruffles and filopodia in adhesion gradient sensing Cancer Research
06/04/2012
Abstract 3031: Angiotensin 1-7 up regulates apoptosis related genes and it preferentially targets differentiated epithelial breast cells Cancer Research
06/04/2012
Abstract 3030: Hypoxia induces BACH1 expression regulating colon cancer metastasis Cancer Research
06/04/2012
Abstract 3029: Biochemical evidence towards the existence of an oncogenic Hsp90 complex Cancer Research
06/04/2012
Abstract 3028: Peroxisome proliferator-activated receptor <= (PPAR{delta}) reveals a critical role in promoting the TGF{beta}-induced EMT and metastasis of non-small cell lung cancer cell (H460) Cancer Research
06/04/2012
Abstract 3027: Dishevelled proteins are highly upregulated in chronic lymphocytic leukemia Cancer Research
06/04/2012
Abstract 3025: CXCR4 is expressed in the nucleus of metastatic prostate cancer cells Cancer Research
06/04/2012
Abstract 3024: Elucidation of WNT signaling pathway players "sFRP-1" and "TCF7L2" as novel potential biomarkers of triple negative breast cancer Cancer Research
06/04/2012
Abstract 3023: Decreased neutral endopeptidase expression regulates the autocrine proliferative effects of substance P on cholangiocarcinoma growth Cancer Research
06/04/2012
Abstract 3022: Overexpression of LPCAT1 and concomitant lipid alterations in gastric cancer Cancer Research
06/04/2012
Abstract 3021: FLT3/ITD acute myeloid leukemia (AML) cells show C-MYC- and PIM-1-mediated CDC25A overexpression despite the presence of intrinsic DNA damage Cancer Research
06/04/2012
Abstract 3020: The role of NF-{kappa}B (p65) and Stat3 interplay in the regulation of radiation-induced, ICAM-1-mediated migration and invasion in glioma Cancer Research
06/04/2012
Abstract 3019: TGF{beta}3 is a less potent inducer of TGF{beta} signaling than TGF{beta}1 in non-small cell lung cancer cells Cancer Research
06/04/2012
Abstract 3018: Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through GnRH-I receptor and mitogen-activated protein kinases (MAPKs)-dependent activation of matrix metalloproteinase (MMP)-2 Cancer Research
06/04/2012
Abstract 3017: Oct4B mediates hypoxia induced epithelial mesenchymal trans-differentiation of lung cancer Cancer Research
06/04/2012
Abstract 3016: Translocation-dependent activation of WNT signaling is essential in synovial sarcoma cells Cancer Research
06/04/2012
Abstract 3015: Crosstalk between <= and <= PKC isoforms and retinoic acid system in malignant phenotype reversion Cancer Research
06/04/2012
Abstract 3014: Expression of hypoxia-inducible factors (HIF-1alpha) mediates Matrix Metalloproteinases (MMP) in colorectal carcinomas progression Cancer Research
06/04/2012
Abstract 3013: Role of prostanoid signaling in lung cancer Cancer Research
06/04/2012
Abstract 3012: The mechanism of UV-induced and prohibitin-mediated apoptosis Cancer Research
06/04/2012
Abstract 3011: Correlation of PERK activation with increased GRP78-binding in UVB-irradiated HaCaT cells Cancer Research
06/04/2012
Abstract 3010: IL-6 enhances migration and ICAM-1 expression of human oral squamous cell carcinoma involves IL-6 receptor signaling pathway Cancer Research
06/04/2012
Abstract 3007: A novel five gene signature predicts overall and recurrence-free survival in NSCLC Cancer Research
06/04/2012
Abstract 3006: A systematical view on key genetic factors affecting somatic copy number alternations in different cancers Cancer Research
06/04/2012
Abstract 3005: Characterization of a lung cancer growth factor, LASEP1 as a serological and prognostic biomarker and a therapeutic target Cancer Research
06/04/2012
Abstract 3004: Biomarker identification through integrative bioinformatics analysis of serous epithelial ovarian cancer tumor samples Cancer Research
06/04/2012
Abstract 3003: Development of a computational framework for disease knowledge modeling and clinical treatment decision support and its application to a rare cancer, malignant peripheral nerve sheath tumor (MPNST) Cancer Research
06/04/2012
Abstract 3002: Identification of frequently altered protein networks in ependymomas Cancer Research
06/04/2012
Abstract 3000: Molecular profiling of residual tumor cells after various chemotherapies shows distinct gene expression patterns in patient-derived breast cancer xenografts Cancer Research
06/04/2012
Abstract 2998: BRG1 (SMARCA4) protein loss has profound effects on the transcriptome of non-small cell lung cancer (NSCLC) cell lines Cancer Research
06/04/2012
Abstract 2997: Peripheral T-cell lymphomas not otherwise specified correspond to distinct mature T-cell populations basing on the global gene expression profile Cancer Research
06/04/2012
Abstract 2996: The prognostic value of a cell cycle proliferation gene signature in bladder cancer Cancer Research
06/04/2012
Abstract 2995: Identifying subtypes of colorectal cancer tumors and cell lines with treatment relevance using iterative clustering (iNMF) Cancer Research
06/04/2012
Abstract 2994: Characteristics of cross-hybridization/cross-alignment of expression in xenograft samples by RNAseq and microarrays Cancer Research
06/04/2012
Abstract 2993: Comparison of copy number variation using exome sequencing and affymetrix SNP6.0 genotype array in human cancer cell lines Cancer Research
06/04/2012
Abstract 2992: Analysis of divergent hypoxic gene expression data in prostate cancer cell lines suggests novel tumor progression biomarkers Cancer Research
06/04/2012
Abstract 2990: Molecular subtyping of glioblastoma based on isoform level network modeling Cancer Research
06/04/2012
Abstract 2989: Identification of a potential tumor suppressor function for SNX9 by mining public genomic data Cancer Research
06/04/2012
Abstract 2988: Exploring the association between immune-related genetic variations and virally mediated head and neck cancer Cancer Research
06/04/2012
Abstract 2987: Regulatory network discovery using 3-way integration of high-dimensional mRNA, miRNA and lncRNA expression data from the entire NCI60 cancer cell line panel Cancer Research
06/04/2012
Abstract 2986: A novel biomarker for gliomas, ELTD1 Cancer Research
06/04/2012
Abstract 2985: Predicting the impact of mutations in cancer using an integrated pathway approach Cancer Research
06/04/2012
Abstract 2984: A comprehensive bioinformatic analysis of the representativity of 460 cancer cell lines as model systems for 88 different clinical cancer types Cancer Research
06/04/2012
Abstract 2983: Nkx3.1 and c-Myc co-regulate shared target genes involved in prostate cancer Cancer Research
06/04/2012
Abstract 2981: Association of a BRCAness profile with outcome and molecular aberrations involving homologous recombination in the TCGA ovarian cancer dataset Cancer Research
06/04/2012
Abstract 2979: Epithelial-mesenchymal gene expression signature defines clinically relevant subtypes in epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 2978: In vivo profiling of migratory tumor cells identifies novel mediators for invasion and dissemination in human breast cancer. Cancer Research
06/04/2012
Abstract 2977: Epithelial mesenchymal plasticity in xenograft models of circulating and disseminated tumour cells from human breast cancer Cancer Research
06/04/2012
Abstract 2976: KSHV-initiated Notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition Cancer Research
06/04/2012
Abstract 2975: Transgenic mouse model of Twist1-induced metastasis reveals genes highly prognostic for human hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 2974: Combating breast cancer brain metastasis by targeting Src family kinases Cancer Research
06/04/2012
Abstract 2973: Adhesion of tumor cells to ECM microarrays identifies novel ECM interactions in metastasis Cancer Research
06/04/2012
Abstract 2972: Neutrophil extracellular traps sequester circulating tumor cells in vitro and in a murine model of metastasis Cancer Research
06/04/2012
Abstract 2971: Human extramedullary bone and bone marrow in mice: First in vivo model of a genetically controlled hematopoietic environment - Role of CTGF and HIF1-{alpha} Cancer Research
06/04/2012
Abstract 2970: Cyclooxygenase-2 mediates significant changes in the extracellular matrix in triple negative breast cancer Cancer Research
06/04/2012
Abstract 2969: Gremlin 1 labels a mesenchymal progenitor cell in the gastrointestinal tract, bone marrow and cancer microenvironment Cancer Research
06/04/2012
Abstract 2967: CCL3 autocrine signaling regulate retention of metastasis associated macrophages and promote breast cancer metastasis Cancer Research
06/04/2012
Abstract 2965: ERG and ETV1 regulate a common transcriptional network in prostate cells but in an opposite fashion Cancer Research
06/04/2012
Abstract 2964: Transcriptional regulation of manganese superoxide dismutase gene reveals a novel mechanism by which FUS/TLS functions as a tumor suppressor Cancer Research
06/04/2012
Abstract 2963: ALK is a MYCN target gene and contributes to cell growth, migration and invasion in neuroblastoma Cancer Research
06/04/2012
Abstract 2962: FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair Cancer Research
06/04/2012
Abstract 2961: Reactivation of EWS-FLI1 suppressed FOXO1 expression as a novel therapeutic strategy for Ewing's sarcoma Cancer Research
06/04/2012
Abstract 2960: Factor dependent chromatin structure and nucleosome dynamics Cancer Research
06/04/2012
Abstract 2959: p53 as a guardian of genomic junk: A novel role for p53 in epigenetic silencing of retroelements Cancer Research
06/04/2012
Abstract 2958: The novel protein kinase STK17A is a direct p53 target gene that mediates response to genotoxic and nutritional stress in a cancer cell context-dependent manner Cancer Research
06/04/2012
Abstract 2957: Uncovering tumor-specific components of the p53 pathway using mouse models and RNAi Cancer Research
06/04/2012
Abstract 2956: High throughput RNAi screening of synthetic lethal genes interacting with the common TP53 mutation R175H Cancer Research
06/04/2012
Abstract 2955: c-Myc suppresses DNA double-strand break repair Cancer Research
06/04/2012
Abstract 2953: Anticipating new biochemical mechanisms of resistance to Raf inhibition in Melanoma Cancer Research
06/04/2012
Abstract 2950: miR-34 prevents in vivo lung tumor initiation and progression in the therapeutically resistant Kras;p53 mouse model Cancer Research
06/04/2012
Abstract 2949: miR-16 is an in vivo suppressor of gastrointestinal tumorigenesis Cancer Research
06/04/2012
Abstract 2948: The role of the RNA binding protein LIN28B in neuroblastoma Cancer Research
06/04/2012
Abstract 2947: B-cell lymphoma in e{alpha}-miR-17~92 transgenic mice Cancer Research
06/04/2012
Abstract 2946: Post-transcriptional regulators of microRNA biogenesis regulate pathogenesis of cancer Cancer Research
06/04/2012
Abstract 2945: Antitumor activities of 2-fluorofucose, an orally active agent that inhibits cell-surface fucosylation Cancer Research
06/04/2012
Abstract 2944: Targeting negative feedback signaling in tyrosine kinase-driven malignancies Cancer Research
06/04/2012
Abstract 2943: KPT-SINE (Selective Inhibitors of Nuclear Export) induce apoptosis in colon cancer cells in-vitro and in-vivo through nuclear localization of Tumor Suppressor Proteins (TSPs) Cancer Research
06/04/2012
Abstract 2942: RKI-1447, a potent ROCK inhibitor with anti-tumor and anti-invasive activities in breast cancer Cancer Research
06/04/2012
Abstract 2940: Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded protein response, induce autophagy and cancer cell death Cancer Research
06/04/2012
Abstract 2939: Discovery and synthesis of highly potent and selective small molecule inhibitors of the histone methyltransferase EZH2 Cancer Research
06/04/2012
Abstract 2938: Polo-like kinase 1: a potential therapeutic target for the management of patients with triple negative breast cancer Cancer Research
06/04/2012
Abstract 2937: An EGFR-STAT3 pathway promotes NF1 peripheral nerve tumorigenesis and transformation Cancer Research
06/04/2012
Abstract 2936: Screen for kinase inhibitors that sensitize pancreatic cancer cells to gemcitabine: When collateral damage is a good thing Cancer Research
06/04/2012
Abstract 2934: Targeting Bruton's tyrosine kinase with PCI-32765 blocks growth and survival of multiple myeloma and Waldenstrom macroglobulinemia via potent inhibition of osteoclastogenesis, cytokines/chemokine secretion, and myeloma stem-like cells in the bone marrow microenvironment Cancer Research
06/04/2012
Abstract 2933: Synthetic lethal screening: A pathway for rational combinatorial therapies for cancer Cancer Research
06/04/2012
Abstract 4365: A cellular model for investigation of circulating tumor cells and identification of therapeutic target and regimen Cancer Research
06/04/2012
Abstract 4364: S1P generated by SphK1 is important not only for primary tumor growth but also for tumor-induced hemangiogenesis and lymphangiogenesis Cancer Research
06/04/2012
Abstract 4363: Tumor regulation of myeloid-derived suppressor cell proliferation, circulation and apoptosis. Cancer Research
06/04/2012
Abstract 4362: Identification and isolation of host factors in response to therapy: an approach to identify new targets for cancer therapy Cancer Research
06/04/2012
Abstract 4361: Role of Id1-induced IGF2 in autocrine/endocrine promotion of esophageal cancer tumorigenesis and metastasis Cancer Research
06/04/2012
Abstract 4360: CD87 is essential for mediating growth-factor induced angiogenesis via distribution of integrin beta-1 Cancer Research
06/04/2012
Abstract 4359: Use of high resolution Doppler imaging for non-invasive, quantitative evaluation of hypoxia-driven neovascularization following surgical ligation of the femoral artery Cancer Research
06/04/2012
Abstract 4358: Notch signaling regulates tumor-induced angiogenesis in SPARC-overexpressed neuroblastoma Cancer Research
06/04/2012
Abstract 4357: The role of lysyl oxidase on proangiogenic phenotypes of tumor endothelial cells Cancer Research
06/04/2012
Abstract 4356: Finding the genetic determinants of response to radiotherapy Cancer Research
06/04/2012
Abstract 4355: Use of MnSOD tet on transgenic mice as a model for evaluating irradiation protection and mitigation Cancer Research
06/04/2012
Abstract 4354: Proteomic analysis of acute radiation response following whole brain irradiation: Is Sirt2 a key player of radiation-induced neurotoxicity Cancer Research
06/04/2012
Abstract 4352: Radiotherapy-induced plasma cytokine changes and skin toxicity in breast cancer patients Cancer Research
06/04/2012
Abstract 4351: Exposure to ionizing radiation causes long-term increase in serum estradiol and activation of PI3K-Akt signaling pathway in mouse mammary gland Cancer Research
06/04/2012
Abstract 4350: Normal stem cells exhibit hypersensitivity and cell death in response to ionizing radiation Cancer Research
06/04/2012
Abstract 4349: Therapeutic radiation induces an epigenetic DNA methylation response Cancer Research
06/04/2012
Abstract 4348: Changes in leukocyte gene expression after computer tomography in children Cancer Research
06/04/2012
Abstract 4347: {gamma}H2AX foci formation in lymphocytes in vivo is increased one hour after very low dose X-radiation in three young children Cancer Research
06/04/2012
Abstract 4346: Influence of ionizing radiation on transcription of human endogenous retrovirus-K (HERV-K) in breast cancer cell lines Cancer Research
06/04/2012
Abstract 4345: Inadequate repair of ionizing radiation damage: A consequence of the invasive tumor phenotype Cancer Research
06/04/2012
Abstract 4344: Ionizing radiation induces adhesion of breast cancer cells to fibronectin through upregulation of integrin alpha5beta1 Cancer Research
06/04/2012
Abstract 4343: Ionizing radiation reduces VLA4 mediated adhesion of macrophage via generation of ROS Cancer Research
06/04/2012
Abstract 4342: Inhibition of radiation-enhanced cell adhesion in breast cancer cells by ROS scanvenger Cancer Research
06/04/2012
Abstract 4341: A novel sonodynamic therapy using hydroxyl radical generated from ultrasound activated TiO2 for human epithelial carcinoma cells Cancer Research
06/04/2012
Abstract 4340: Increased cytokine and chemokine expression in U87MG glioblastoma cells after large clinically relevant single doses of ionizing radiation Cancer Research
06/04/2012
Abstract 4338: Monitoring radiation response in tumor vasculature using intravital photoacoustic imaging in a murine window chamber model in vivo Cancer Research
06/04/2012
Abstract 4337: Effect of sorafenib in combination with cytostatic agents on hepatoblastoma in vitro and in vivo Cancer Research
06/04/2012
Abstract 4336: Macrophage migration inhibitory factor (MIF) plays roles in proliferation, survival and migration of Ewing tumor cells by activation of a CD74-CD44 receptor complex Cancer Research
06/04/2012
Abstract 4335: The genomic landscape of childhood pre-B acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 4334: Expression of PID1 correlates with PFS in pediatric medulloblastomas and negatively impacts growth of medulloblastoma, glioblastoma and AT/RT brain tumor cell lines Cancer Research
06/04/2012
Abstract 4333: Difference in the synergistic effect of cytotoxicity in pediatric brain stem gliomas and adult glioblastomas to combination treatment with temozolomide and molecular target-specific agents Cancer Research
06/04/2012
Abstract 4332: Proprotein convertases as target for therapy of pediatric sarcomas Cancer Research
06/04/2012
Abstract 4331: Analysis of stem cell-like compartments in Embryonal Rhabdomyosarcoma modulated by Sonic Hedgehog signaling Cancer Research
06/04/2012
Abstract 4330: Transcriptional regulation of gp170 by YY1 and prognostic significance in childhood acute lymphoblastic leukemia (ALL) Cancer Research
06/04/2012
Abstract 4329: Modulation of metastatic behavior in breast cancers harboring p53 mutations Cancer Research
06/04/2012
Abstract 4328: Specific epidermal growth factor receptor autophosphorylation sites promote epithelial cell chemotaxis and restitution Cancer Research
06/04/2012
Abstract 4327: Loss of the APC tumor suppressor alters breast cancer cell migration and invasion Cancer Research
06/04/2012
Abstract 4326: The potential role of IMP-3 and PDPN in invadopodia formation and collective cancer invasion: Anti-invadopodia therapy as a therapeutic target Cancer Research
06/04/2012
Abstract 4325: CD99 suppresses osteosarcoma cell migration by favouring the oncosoppressor N-cadherin/beta-catenin signalling pathway in contrast to ezrin. Cancer Research
06/04/2012
Abstract 4324: Axl receptor tyrosine kinase expression regulates tumor cell invasion and migration in colorectal cancer Cancer Research
06/04/2012
Abstract 4323: MED28 (magicin/EG-1) modulates MEK1 (MAP2K1)-dependent cellular migration in human breast cancer cells Cancer Research
06/04/2012
Abstract 4322: Iron increases the invasiveness of prostate cancer cells in vitro: Mechanisms and inhibition by the antioxidant ebselen Cancer Research
06/04/2012
Abstract 4321: EGFR signaling in glioblastoma regulates the expression of a brain specific isoform of alphaPIX/Arhgef6 to promote invasion Cancer Research
06/04/2012
Abstract 4320: Overexpression of Homeobox A5 decreases the invasive and migration capabilities of lung cancer cells Cancer Research
06/04/2012
Abstract 4319: Gene expression profiling of isolated small migratory and invasive breast cancer cells at different times during chemotaxis Cancer Research
06/04/2012
Abstract 4317: Stim1 and Orai1 are critical regulators of melanoma invasion and anoikis Cancer Research
06/04/2012
Abstract 4316: Villin expression is frequently lost in colon cancers with microsatellite instability. Cancer Research
06/04/2012
Abstract 4315: A novel role for the high affinity IL13 receptor in glioblastoma multiforme Cancer Research
06/04/2012
Abstract 3134: Integrin {alpha}6{beta}4 upregulates EGFR ligands in pancreatic cancer cells Cancer Research
06/04/2012
Abstract 3133: Regulatory sequences of the ATP-Binding Cassette Transporter A1 gene are hypermethylated in prostate cancer resulting in loss of gene expression Cancer Research
06/04/2012
Abstract 3132: Dynamic changes of epigenetic abnormalities during initiation and progression of adult T-cell leukemia/lymphoma (ATLL) Cancer Research
06/04/2012
Abstract 3131: Higher IGF-II expression in Vietnamese triple negative breast cancer tumors is dependent on Biallelic or Monoallelic IGF-II with ApaI SNP Cancer Research
06/04/2012
Abstract 3130: Targeted DNA methylation reprogrammed differentiation and tumorigenesis of mesenchymal stem cells Cancer Research
06/04/2012
Abstract 3129: XPC protein attenuation and deficiency in tobacco smoke-induced DNA hypermethylation of tumor suppressor genes Cancer Research
06/04/2012
Abstract 3128: Diet folate, DNA methylation and genetic polymorphisms of MTHFR C677T in esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 3127: Cigarette smoke condensate (CSC) induces differential expression and promoter methylation profiles of critical genes involved in lung cancer in NL-20 lung cells in vitro: Short-term and chronic exposure Cancer Research
06/04/2012
Abstract 3126: Effect of folic acid and docetaxel on the multidrug and folate transporter ABCG2 in prostate cancer Cancer Research
06/04/2012
Abstract 3125: Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa Cancer Research
06/04/2012
Abstract 3124: Smoking effects on CYP24A1 in lung adenocarcinoma: Epigenetic changes by smoking Cancer Research
06/04/2012
Abstract 3122: The DNA-PK inhibitor NU7441 inhibits non-homologous end joining, enhances radio- and chemosensitivity and increases dependence on homologous recombination in hepatocellular carcinoma cell lines Cancer Research
06/04/2012
Abstract 3121: Systematic analysis of the DNA synthesis fidelity of somatic mutations of polymerase beta found in prostate cancer Cancer Research
06/04/2012
Abstract 3120: Functional characterization of ERCC1 isoforms in NSCLC Cancer Research
06/04/2012
Abstract 3119: A synthetic lethal screen identifies genetic determinants for gemcitabine sensitivity in pancreatic cancer Cancer Research
06/04/2012
Abstract 3118: The proteasome inhibitor Bortezomib rescues clinically identified unstable missense variants of the DNA mismatch repair protein Msh2 Cancer Research
06/04/2012
Abstract 3117: Complex genomic regions associated with ERBB2 amplification in breast cancer Cancer Research
06/04/2012
Abstract 3116: Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in ovarian cancer Cancer Research
06/04/2012
Abstract 3115: PARP overactivation predicts the susceptibility of human cancer cells to apoptosis induction by PARP inhibitors Cancer Research
06/04/2012
Abstract 3114: Mutational inactivation of STAG2 causes aneuploidy in human cancer Cancer Research
06/04/2012
Abstract 3112: Molecular events in DNA damage induced downstream of blockade of the Hedgehog (HH) signaling axis in colon carcinoma cells Cancer Research
06/04/2012
Abstract 3111: Synthetic lethality in head and neck cancer Cancer Research
06/04/2012
Abstract 3109: Correlation between genomic aberrations and the DNA damage response in bladder cancer Cancer Research
06/04/2012
Abstract 3108: Exploring base excision repair variants as potential defining events in cancer patient populations and characterization of models for pre-clinical studies Cancer Research
06/04/2012
Abstract 3107: Association of alterations in homologous recombination repair genes with survival and chemotherapy sensitivity in patients with high-grade serous ovarian cancer Cancer Research
06/04/2012
Abstract 3106: Collagen-mediated chromatin remodeling promotes chemoresistance in pancreatic cancer Cancer Research
06/04/2012
Abstract 3105: Chromosome 18q encodes a chromosomal instability suppressor locus in colorectal cancer Cancer Research
06/04/2012
Abstract 2794: Cytotoxic and vascular disrupting activity of EHT 6706, a novel tubulin polymerization inhibitor Cancer Research
06/04/2012
Abstract 2792: Novel anti-microtubule agents for breast cancer Cancer Research
06/04/2012
Abstract 2791: Disruption of EB1 comets from microtubule "plus" ends and induction of microtubule catastrophes are intrinsic mechanisms of patupilone-induced inhibition of glioblastoma cell migration Cancer Research
06/04/2012
Abstract 2790: Localization of the binding site for Peloruside A and Laulimalide on beta-tubulin by physical and biological means Cancer Research
06/04/2012
Abstract 2789: Interaction of (+)-discodermolide-Taxol hybrids with microtubules Cancer Research
06/04/2012
Abstract 2787: Antitumor activity and toxicity of FL118, a novel IAP/Bcl-2 antiapoptotic genes-selective inhibitor, in animal models of human tumor via the clinic-compatible intravenous (i.v.) routes Cancer Research
06/04/2012
Abstract 2786: Potent inhibition of human liposarcoma cell growth and survival by novel modulators of the MDM2-p53 interaction Cancer Research
06/04/2012
Abstract 2785: Discovery of a novel HDM2 inhibitor with potent in vivo anti-tumor activity Cancer Research
06/04/2012
Abstract 2783: Inhibition of prosurvival autophagy by the BH3-mimetic obatoclax sensitizes antiestrogen-resistant breast cancer cells to apoptosis Cancer Research
06/04/2012
Abstract 2782: Bcl-2 selective antagonists show antitumor activity without dose limiting platelet toxicity Cancer Research
06/04/2012
Abstract 2780: Bortezomib induces autophagy in hepatocellular carcinoma through the inhibition of CIP2A independent of proteasome inhibition. Cancer Research
06/04/2012
Abstract 2778: Development of non-covalent reversible proteasome inhibitors Cancer Research
06/04/2012
Abstract 2777: Suppression of multiple myeloma via non-canonical inhibition of NF-{kappa}B Cancer Research
06/04/2012
Abstract 2776: Inhibition of Nek2 by novel small molecules affects proteasome activity Cancer Research
06/04/2012
Abstract 2775: Antitumor activity of cabazitaxel in pediatric tumor xenografts Cancer Research
06/04/2012
Abstract 2774: Anti-cancer activity of the tumor-selective, hypoxia-inducing, agent BNC105 in platinum resistant ovarian cancer Cancer Research
06/04/2012
Abstract 2773: HSP90 inhibitors target KRAS mutant human tumors through degradation of STK33 Cancer Research
06/04/2012
Abstract 2772: AT13387, an HSP90 inhibitor, is effective in both vemurafenib-sensitive and -resistant melanoma models Cancer Research
06/04/2012
Abstract 2771: HSP90 inhibitor NVP-AUY922 exhibits the potent antiproliferative effect in gastrointestinal cancer cells with a lack of PTEN expression Cancer Research
06/04/2012
Abstract 2770: Antitumor activity of heat shock protein 90 (HSP90) inhibitor AT13387 in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 2769: The development of 19-substituted benzoquinone ansamycins as potential anticancer drugs Cancer Research
06/04/2012
Abstract 2768: IDH1057, A novel, synthetic, small molecule inhibitor of heat shock protein 90(Hsp90) Cancer Research
06/04/2012
Abstract 2767: AUY922, a heat shock protein 90 inhibitor, plus 5-fluorouracil inhibits tumors synergistically in gastric cancer MKN45 xenograft via down regulation of multiple pivotal growth factor receptors and oncoproteins Cancer Research
06/04/2012
Abstract 2766: Targeting heat shock proteins: Novel strategies for treating prostate cancer Cancer Research
06/04/2012
Abstract 2765A: Co-treatment of human pancreatic cancer MiaPaCa-2 Cells with PNC-27 and Gemzar Cancer Research
06/04/2012
Abstract 2765: Combination strategies for management of ovarian cancer using doxorubicin and withaferin A Cancer Research
06/04/2012
Abstract 2764: Effect of PNT2258 combinations with docetaxel, dacarbazine, or vemurafenib on the A375 melanoma xenograft Cancer Research
06/04/2012
Abstract 2762: Phase I study of pazopanib and ixabepilone in patients with solid tumors Cancer Research
06/04/2012
Abstract 2761: Co-administration of the short-chain sphingolipid N-octanoyl-glucosylceramide improves doxorubicin therapy by enhancing intracellular drug accumulation in vivo Cancer Research
06/04/2012
Abstract 2760: Gemcitabine induced lytic EBV replication and confers ganciclovir susceptibility to EBV-positive gastric cancer Cancer Research
06/04/2012
Abstract 2758: Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: Evidence for the role of C-Jun N-terminal kinase activation Cancer Research
06/04/2012
Abstract 2757: TAS-106, a newly synthesized RNA polymerase inhibitor, combined with cisplatin exhibits potent synergistic growth-inhibitory effect via Vaults dysfunction Cancer Research
06/04/2012
Abstract 2756: Combination therapy of doxorubicin and the acid-sensitive albumin-binding prodrug of doxorubicin INNO-206 induces complete regressions in a xenograft pancreatic carcinoma model demonstrating excellent tolerability Cancer Research
06/04/2012
Abstract 2755: Enhanced anti-tumor effects using a combinatorial targeted treatment strategy in a preclinical model of prostate cancer Cancer Research
06/04/2012
Abstract 2754: Cinnamoyl quinolines are novel autophagy inhibitors and enhance antitumor activity of 2-deoxyglucose Cancer Research
06/04/2012
Abstract 2753: The addition of low dose 17-DMAG to BIBW-2992 effectively inhibits lung cancer cells with acquired resistance by T790M mutation Cancer Research
06/04/2012
Abstract 2752: In vivo evaluation of dacomitinib (PF-00299804) in patient-derived salivary gland tumor models: Identification of a potential treatment options for adenoid cystic carcinoma Cancer Research
06/04/2012
Abstract 2751: Protective effects of phenylaminoethyl selenide (PAESe) on doxorubicin-induced cardiotoxicity in vitro and in vivo Cancer Research
06/04/2012
Abstract 2749: YM155, a small molecule survivin suppressant, sensitizes human B-cell non-Hodgkin lymphoma to rituximab-induced apoptosis Cancer Research
06/04/2012
Abstract 2748: Prostate-specific inhibition of PI3 Kinase and protein synthesis as a therapy for advanced hormone-refractory prostate cancer Cancer Research
06/04/2012
Abstract 2747: Synergistic antileukemic activity of F14512 in combination with AraC Cancer Research
06/04/2012
Abstract 2746: Thiazolidinediones augment anticancer effects of gemcitabine on human pancreatic cancer cells through PPAR{delta} activation Cancer Research
06/04/2012
Abstract 2745: INK128, a TORC1/2 kinase inhibitor, enhances the efficacy of cytotoxic therapies in endometrial tumor models Cancer Research
06/04/2012
Abstract 2744: Identification of synergistic effect of autophagy inhibitors and resveratrol on BRCA1 mutant cancer cells Cancer Research
06/04/2012
Abstract 2743: Triapine sensitizes ovarian cancer cells to platinum drugs and PARP inhibitors Cancer Research
06/04/2012
Abstract 2742: Cerebral microdialysis for simultaneous sampling of crenolanib (PDGFR inhibitor) and erlotinib (EGFR inhibitor) in mouse models of glioma Cancer Research
06/04/2012
Abstract 2741: Synergistic inhibition of tumor growth and overcoming chemo-resistance by simultaneously targeting key components in DNA damage/repair, epigenetic, and putative cancer stem cell signaling pathways using novel dual-functional DNA-alkylating/HDAC inhibitor and tumor suppressor gene nanoparticles in lung cancer Cancer Research
06/04/2012
Abstract 2740: Antitumor activity of BMS-754807, a small molecule inhibitor of insulin-like growth factor-1 receptor / insulin receptor, in combination with gemcitabine in pancreatic cancer Cancer Research
06/04/2012
Abstract 2739: Panobinostat potentiates the cytotoxic effects of ara-C and daunorubicin on acute myeloid leukemia cells through suppressing the DNA damage response Cancer Research
06/04/2012
Abstract 2738: c-Met antibody LY2875358 (LA480) has pre-clinical enhanced efficacy with gastric cancer standard-of-care in vitro and in vivo Cancer Research
06/04/2012
Abstract 2737: Anti-proliferative action of metformin on various types of human lung cancer cell lines Cancer Research
06/04/2012
Abstract 2736: PIM2 is up-regulated in response to metformin-induced cell death triggered by ER stress/UPR in ALL lymphoblasts Cancer Research
06/04/2012
Abstract 2735: Effects of metformin on a non-small cell lung cancer cell line with an EGFR mutation Cancer Research
06/04/2012
Abstract 2734: c-Met antibody LY2875358 (LA480) shows differential antitumor effects in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 2732: Internalization of the dual-specific immunotoxin D2C7-(scdsFv)-PE38KDEL in malignant glioma cell lines Cancer Research
06/04/2012
Abstract 2731: Cetuximab resistance is associated with increased dependence on lipogenesis Cancer Research
06/04/2012
Abstract 2730: Anti-Her2/neu immunotoxins: Impact of monovalent and bivalent designs on in vitro and in vivo antitumor efficacy Cancer Research
06/04/2012
Abstract 2729: Suppression of hematogenous metastasis by mouse and murine/human chimeric anti-Aggrus/podoplanin antibodies Cancer Research
06/04/2012
Abstract 2728: Onartuzumab (MetMAb) restores sensitivity to erlotinib in EGFR mutant NSCLC cells expressing HGF Cancer Research
06/04/2012
Abstract 2727: Bispecific, hexavalent antibodies (HexAbs) targeting IGF-1R and either Trop-2 or CEACAM6 inhibit anchorage-independent growth and invasion of antigen-expressing breast and pancreatic cancer cell lines in vitro Cancer Research
06/04/2012
Abstract 2726: Efficacy and candidate biomarker evaluation for the anti-mesothelin antibody drug conjugate (ADC) BAY 94-9343, mesothelin-ADC in mesothelin-positive preclinical xenograft models Cancer Research
06/04/2012
Abstract 2725: Preclinical development of an Fc-enhanced anti-B7-H3 monoclonal antibody with potent anti-tumor activity Cancer Research
06/04/2012
Abstract 4456: Biomarkers of breast cancer risk in a randomized trial of a low-fat or low-carbohydrate weight loss intervention and physical activity among overweight and obese premenopausal women Cancer Research
06/04/2012
Abstract 4455: Mild and moderate early-life stressors differentially affect stress reactivity and mammary tumorigenesis in BALB/c mice: A new look at the stress and breast cancer relationship Cancer Research
06/04/2012
Abstract 4454: Global health as the key to a new paradigm in cancer research Cancer Research
06/04/2012
Abstract 4453: Smoking characteristics, intention to quit, and nicotine dependence in patients with head and neck cancer Cancer Research
06/04/2012
Abstract 4452: Mother-daughter communication and breast cancer prevention knowledge, attitudes, and behaviors between Hispanic and non-Hispanic college women Cancer Research
06/04/2012
Abstract 4451: The NCI Early Detection Research Network (EDRN) urinary PCA3 validation trial Cancer Research
06/04/2012
Abstract 4450: Navigating Latinas with breast screen abnormalities to diagnosis: The Six Cities Study Cancer Research
06/04/2012
Abstract 4449: Initial medical attention on patients with stage I or II non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4448: Fecal miRNA test using microRNA expressions of exfoliated colonocytes for colorectalcancer screening Cancer Research
06/04/2012
Abstract 4447: In search of the ideal cancer screening test Cancer Research
06/04/2012
Abstract 4446: Evaluation of the sensitivity and specificity of a fluorescent nanobeacon for imaging colorectal cancer Cancer Research
06/04/2012
Abstract 4445: Defining a pipeline to use next generation sequencing for genetic testing in hereditary cancer Cancer Research
06/04/2012
Abstract 4444: BRCA1 Circos: A visualization tool for BRCA1 missense variants Cancer Research
06/04/2012
Abstract 4443: Body weight status predicts pre-treatment risk of PSA failure in men with clinically localized prostate cancer Cancer Research
06/04/2012
Abstract 4442: Activity participation and quality of life for persons with breast cancer: A longitudinal study Cancer Research
06/04/2012
Abstract 4441: Informational needs of prostate cancer survivors: Findings from the Michigan Prostate Cancer Follow-Back Study Cancer Research
06/04/2012
Abstract 4439: Childhood cancer late effects: Knowledge base and meaningful resources from a community perspective Cancer Research
06/04/2012
Abstract 4438: Effect of weight gain on quality of life in young indigent breast cancer survivors Cancer Research
06/04/2012
Abstract 4437: Subsquamous extension of Barrett epithelium is a regular event Cancer Research
06/04/2012
Abstract 4436: Chronic inflammation and gastric carcinogenesis: the role of CD44 variant expression Cancer Research
06/04/2012
Abstract 4435: Overexpression of Rhotekin confers gastric cancer cells resistance to interferon-{alpha}-mediated growth inhibition Cancer Research
06/04/2012
Abstract 4434: Development of pancreatic ductal adenocarcinoma (PDAC) by the expression of temperature-sensitive SV40 large T antigen (tsTAg) and K-ras G12D on pancreatic epithelial linage cells Cancer Research
06/04/2012
Abstract 4432: Pancreatic normal duct epithelial and cancer cells express an autocrine catecholamine loop that is activated by the {alpha}3, 5 and 7 nicotinic acetylcholine receptors Cancer Research
06/04/2012
Abstract 4431: NFATc1 silencing increases sensitivity of pancreatic cancer cells to phosphosulindac Cancer Research
06/04/2012
Abstract 4430: Acute inflammation-induced abrogation of base excision repair as a potential mechanism of cancer initiation in inflammation-mediated hepatocarcinogenesis Cancer Research
06/04/2012
Abstract 4429: An investigation on p21-activated protein kinase 1 inhibitor, IPA-3, in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4428: Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in mice lacking hepatic retinoid storage Cancer Research
06/04/2012
Abstract 4427: Role of cytochrome P450 (CYP)1A2 in the sustained induction of CYP1A1 by the carcinogen, 3-methylcholanthrene (MC) in mouse heptoma cells (hepa-1) Cancer Research
06/04/2012
Abstract 4426: Is development of hepatocellular carcinoma driven by liver homing signals? Cancer Research
06/04/2012
Abstract 4425: Specific miRNA expression profiles of non-tumor liver tissues predict the risk for multicentric occurrence of hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4424: Roles of the primary bile acid receptor FXR in liver repair and tumorigenesis Cancer Research
06/04/2012
Abstract 4423: Transgenic liver expression of human arylamine N-acetyltransferase NAT2 restores sensitivity of male Nat1/2 null mice to 4-aminobiphenyl-induced liver tumorigenesis Cancer Research
06/04/2012
Abstract 4422: Activation of beta-catenin/TCF-4 signaling leading to intestinal tumorigenesis in APCMin/+ mice is radiation quality dependent Cancer Research
06/04/2012
Abstract 4420: Serum regulates reovirus-mediated cytopathy in K-Ras activated colorectal cancer and intestinal epithelial cell lines Cancer Research
06/04/2012
Abstract 4419: The role of ABC transporters in PhIP-induced colon carcinogenesis Cancer Research
06/04/2012
Abstract 4418: The histopathological characteristics of mucin-depleted foci in patients with sporadic colorectal cancer Cancer Research
06/04/2012
Abstract 4417: Induction of colonic cre-recombinase expression in carbonic anhydrase1-cre transgenic mice by dextran sulfate sodium Cancer Research
06/04/2012
Abstract 4416: The pre-neoplastic lesion, mucin-depleted foci, reveals as de novo high-grade dysplasia in rat colon carcinogenesis Cancer Research
06/04/2012
Abstract 4415: Intestinal tumorigenesis increased by obesity caused by leptin deficiency and/or high fat diet in ApcMin x Lepob mice involves blood glucose dysregulation Cancer Research
06/04/2012
Abstract 4414: Distinct taxonomic, metagenomic and metabolomic profiles from a comprehensive gut flora analysis in healthy and colon adenoma African Americans Cancer Research
06/04/2012
Abstract 4413: Rosiglitazone prevents graft-versus-host disease (GVHD) Cancer Research
06/04/2012
Abstract 4412: Combining cytokine gene therapy with conventional cancer chemotherapyfor treatment of metastatic renal cell carcinoma Cancer Research
06/04/2012
Abstract 4411: Farletuzumab (mAb003), a neutralizing monoclonal antibody to folate receptor alpha, enhances paclitaxel efficacy in an ovarian cancer model Cancer Research
06/04/2012
Abstract 4410: Neutralizing Endosialin antibody, MORAb-004, enhances efficacy of TAXOTERE in a metastatic melanoma model Cancer Research
06/04/2012
Abstract 4409: A modular polymer platform for the delivery of cytokines is effective in the treatment of head and neck squamous cell carcinoma (HNSCC) Cancer Research
06/04/2012
Abstract 4408: Targeting cancer stem cells as potential new therapy for pancreatic cancer Cancer Research
06/04/2012
Abstract 4406: Clinical efficacious combined chemo/immunotherapy differently activates AKT pathway and functionality of gp100 and Melan-A specific T cell clones Cancer Research
06/04/2012
Abstract 4405: Immune modulation and Treg suppression with metronomic cyclophosphamide enhances the anti-tumor effect of a therapeutic peptide vaccine in a murine model Cancer Research
06/04/2012
Abstract 4404: Microparticle generation and activation after treatment with paclitaxel and bavituximab combination therapy in metastatic breast cancer Cancer Research
06/04/2012
Abstract 4403: Combined antagonism of the IL-4R and IKK{alpha} inhibits melanoma tumor growth in immunocompetent mice Cancer Research
06/04/2012
Abstract 4402: The anti-tumor effects of two novel multivalent/multifunctional agents derived from hR1, a humanized anti-insulin-like growth factor receptor-I monoclonal antibody, are enhanced in renal cell carcinoma and synergistic with an mTOR inhibitor Cancer Research
06/04/2012
Abstract 4400: Novel combination of carbonic anhydrase inhibitor with a phytochemical for treatment of human bronchial carcinoids Cancer Research
06/04/2012
Abstract 4399: Immunostimulatory effects of HSP90 inhibition: Insights from combinational immunotherapies targeting EphA2 Cancer Research
06/04/2012
Abstract 4398: Liver is a major primary target for the Toll-like receptor-5 agonist CBLB502 providing radioprotective, antimicrobial and antitumor responses Cancer Research
06/04/2012
Abstract 4397: A TLR4-interacting peptide (SPA4) reduces the lipopolysaccharide-stimulated NF-kappaB signaling, cytokines and migration of colon cancer cells Cancer Research
06/04/2012
Abstract 4396: Combination of intratumoral regulated IL-12 gene delivery and systemic chemotherapy with Palifosfamide (IPM-Tris) enhances anti-tumor effects in breast cancer (4T1) model Cancer Research
06/04/2012
Abstract 4394: Combination therapy of dendritic cells and cytokine-induced killer cells prolong survival after the removal of tumor in gastrointestinal cancer Cancer Research
06/04/2012
Abstract 4393: Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF Cancer Research
06/04/2012
Abstract 4392: Vaccination targeting IGF-IR sensitizes tumors to tamoxifen therapy in an anti-estrogen resistant mouse model Cancer Research
06/04/2012
Abstract 4391: CD20 as a target for therapy in solid tumors Cancer Research
06/04/2012
Abstract 4390: Heat shock protein (HSP) Grp94-targeted combinatorial immunotherapy for pancreatic cancer Cancer Research
06/04/2012
Abstract 4389: Impact of regulatory T cell depletion on dendritic cell-tumor fusion vaccine immunotherapy Cancer Research
06/04/2012
Abstract 4388: Combination therapy with anti-CTLA-4 plus leuprolide acetate in the pre-surgical setting of patients with regional, high-risk prostate cancer Cancer Research
06/04/2012
Abstract 4387: Antiviral and antitumoral effects of the anti-CTLA4 agent tremelimumab in patients with hepatocellular carcinoma (HCC) and chronic hepatitis C virus (HCV) infection: Results from a phase II clinical trial Cancer Research
06/04/2012
Abstract 4386: Effects of interferon-{alpha}-transduced tumor cell vaccines and blockade of programmed cell death 1 on the growth of established tumors Cancer Research
06/04/2012
Abstract 4385: PD-1 blockade enhances T-cell migration to tumor through induction of IFN-{gamma} inducible chemokines Cancer Research
06/04/2012
Abstract 4384: Targeting of 4-1BB by monoclonal antibody, PF-05082566, enhances T cell function and promotes antitumor activity Cancer Research
06/04/2012
Abstract 4383: Targeting tumor microenvironment with gemcitabine is useful for the treatment of pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 4382: Inhibition of SDF-1 (CXCL12) using the Spiegelmer NOX-A12 markedly delays the recurrence of ENU-induced rat brain tumors following irradiation Cancer Research
06/04/2012
Abstract 4380: Effect of sunitinib on endothelial-pericyte cell interaction Cancer Research
06/04/2012
Abstract 4379: Activating the prostaglandin I2-IP signaling suppresses metastasis in lung cancer Cancer Research
06/04/2012
Abstract 4378: Pericyte coverage of differentiated vessels inside tumor vasculature is an independent unfavorable prognostic factor for patients with clear cell renal cell carcinoma Cancer Research
06/04/2012
Abstract 4377: Metronomic oral prodrug of gemcitabine (LY2334737) causes antitumor effects with concomitant increase in intratumoral blood flow Cancer Research
06/04/2012
Abstract 4375: Sunitinib alone and in combination with SN-38 is active against anaplastic thyroid cancer Cancer Research
06/04/2012
Abstract 4374: Combination of Bevacizumab and oncolytic virus hRr3 in an experimentalmodel of pancreatic carcinoma Cancer Research
06/04/2012
Abstract 4373: Targeting FGFR system in a model of HCC Cancer Research
06/04/2012
Abstract 4372: Chronic myeloid leukemia (CML) exosomes promote angiogenesis in a Src-dependent fashion in vitro and in vivo Cancer Research
06/04/2012
Abstract 4371: RRx-001 modulates intratumor blood flow in SCCVII and U87 tumors Cancer Research
06/04/2012
Abstract 4369: The macrophage migration inhibitory factor (MIF) contributes to tumor growth and metastasis though interaction with the host immune response Cancer Research
06/04/2012
Abstract 4368: Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses Cancer Research
06/04/2012
Abstract 4367: Contribution of malignant thrombocytosis to ovarian cancer proliferation and resistance to chemotherapy-induced-apoptosis through Platelet Derived Growth Factor Receptor-Alpha (PDGFRA) signaling Cancer Research
06/04/2012
Abstract 4366: miR-126 reduces the tumorigenicity of melanoma cells in vitro and alters the melanoma microenvironment Cancer Research