Medical Research Articles Published in June 2012

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06/04/2012
Abstract 4314: Dynamin 2 mediates PDGFR{alpha}-SHP-2-promoted glioblastoma growth and invasion Cancer Research
06/04/2012
Abstract 4313: A novel endoplasmic reticulum protein promotes cancer invasion/metastasis Cancer Research
06/04/2012
Abstract 4312: E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration but not for its RhoGDI binding activity Cancer Research
06/04/2012
Abstract 4311: EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase Cancer Research
06/04/2012
Abstract 4310: TWIST1, a B-RAF effector, promotes invasion and is a novel regulator of MMP-1 in human melanoma cells Cancer Research
06/04/2012
Abstract 4309: DYRK2 regulates cancer invasiveness via Snail/E-cadherin pathway Cancer Research
06/04/2012
Abstract 4308: ZEB1 mediates invasion and chemoresistance of glioblastoma Cancer Research
06/04/2012
Abstract 4307: The effect of ablating ADF/cofilin pathway during skin homeostasis and tumorigenesis Cancer Research
06/04/2012
Abstract 4306: Lack of TGF-{beta} signaling induces a switch from single to collective cell migration in vivo Cancer Research
06/04/2012
Abstract 4305: Dissecting the requirements for astrocytoma and invasion using genetically-engineered mouse models Cancer Research
06/04/2012
Abstract 4304: A microfluidic invasion assay to investigate the mechanisms involved in prostate cancer metastasis to bone Cancer Research
06/04/2012
Abstract 4303: A high-throughput cell invasion assay combined with reverse phase protein microarrays for rational development of drug combination strategies targeting tumor invasion Cancer Research
06/04/2012
Abstract 4302: Odontogenic ameloblast-associated protein (ODAM) alters the growth and migration of human melanoma cells Cancer Research
06/04/2012
Abstract 4301: Shear stress induces Rac1/Rab5 circular ruffling/endosomes at the apical surface of metastatic esophageal tumor cells enhancing spreading and motility responses Cancer Research
06/04/2012
Abstract 4300: Comparative assessment of cell viability and motility kinetics by novel real-time technology and classic endpoint assays Cancer Research
06/04/2012
Abstract 4299: Evaluation of a new multimodality voxel-based imaging biomarker for therapeutic response assessment in GBM Cancer Research
06/04/2012
Abstract 4298: In-utero, but not pubertal, soy exposure suppresses estrogen-regulated gene expression in non-human primate breast Cancer Research
06/04/2012
Abstract 4297: Racial/ethnic disparities in breast cancer radiosensitivity Cancer Research
06/04/2012
Abstract 4296: Ultrasmall gadolinium-loaded polymer nanoparticles for imaging in glioblastoma Cancer Research
06/04/2012
Abstract 4295: Multifunctional nanoconstructs for tumor visualization using contrast enhanced MRI Cancer Research
06/04/2012
Abstract 4294: GE152: In vivo detection of tumor apoptosis as a tool for assessment of therapeutic efficacy Cancer Research
06/04/2012
Abstract 4293: In vivo imaging and tracking of a PARP inhibitor at single-cell resolution Cancer Research
06/04/2012
Abstract 4292: In vivo and in vitro imaging of Cyclooxygenase-2 in tumor Cancer Research
06/04/2012
Abstract 4291: Near-infrared optical imaging visualizes tumor cell death induced by adoptive transferred T cells Cancer Research
06/04/2012
Abstract 4290: Visualizing immune surveillance in lung metastasis progression Cancer Research
06/04/2012
Abstract 4289: MRI-guided intra-arterial delivery of SPIO-labeled natural killer cells to hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4288: in vivo Imaging of early inflammation response in bacterial infection Cancer Research
06/04/2012
Abstract 4287: M13-stabilized single-walled carbon nanotubes as nanoprobes for second near-infrared window fluorescent imaging of targeted tumors Cancer Research
06/04/2012
Abstract 4286: Oral caffeine during voluntary exercise markedly inhibits skin carcinogenesis and decreases cytokines associated with inflammation in UVB-treated mice Cancer Research
06/04/2012
Abstract 4285: Visualizing cancer vaccine clearance in vivo using magnetic resonance imaging Cancer Research
06/04/2012
Abstract 4284: Prognosis of prostate cancer using gene expression changes in stroma Cancer Research
06/04/2012
Abstract 4283: Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis Cancer Research
06/04/2012
Abstract 4282: Analysis of epithelial and stromal cell networks in prostate cancer by gene expression profiles Cancer Research
06/04/2012
Abstract 4281: Adaptive post-translational regulation of the thiamine transporter THTR1 in breast cancer cells during hypoxic stress Cancer Research
06/04/2012
Abstract 4280: Genome-wide expression and methylation analysis in CD31+ cells from African American and Caucasian American benign and malignant prostate tissue Cancer Research
06/04/2012
Abstract 4279: Inflammation increases colonic tumor multiplicity and stage in Pirc rats: A priming effect Cancer Research
06/04/2012
Abstract 4278: IFN-{gamma} and TNF-{alpha} favor the progression of prostate cancer in distinct ways Cancer Research
06/04/2012
Abstract 4277: Comparative gene expression analysis of proliferating stromal cells from pancreatic ductal adenocarcinoma, pancreatitis and normal pancreas Cancer Research
06/04/2012
Abstract 4276: PGE2 induces LEF-1 expression in breast cancer cells, but is not required for the nuclear localization of beta-catenin Cancer Research
06/04/2012
Abstract 4275: PLA2 activities in human epithelial ovarian cancer ascites Cancer Research
06/04/2012
Abstract 4274: HIF2{alpha}/Sp1/mTOR interaction mediates a deacetylation-dependent FVII gene activation under serum deprived condition in ovarian cancer cells Cancer Research
06/04/2012
Abstract 4273: C-kit expression promotes prostate cancer cell migration and invasion through Brca2 downregulation Cancer Research
06/04/2012
Abstract 4272: An integrated platform for quantifying gene expression in co-cultured cells Cancer Research
06/04/2012
Abstract 4271: Fibroblast transcriptome sequencing reveals different gene expression profiles among distinct subtypes of breast cancer and normal mammary tissue Cancer Research
06/04/2012
Abstract 4270: Novel stromal angiogenic factor MFAP5 in ovarian cancer progression Cancer Research
06/04/2012
Abstract 4269: Opposite effect of ECM features in breast carcinoma progression according to tumor cell differentiation Cancer Research
06/04/2012
Abstract 4268: Gene signature of host irradiation from Trp53 null mammary tumors detects radiation-preceded human cancers and has prognostic value for sporadic human breast cancer Cancer Research
06/04/2012
Abstract 4267: Gene expression profile of fibroblasts from different topographical origins in breast cancer patients Cancer Research
06/04/2012
Abstract 4266: Identification of gene expression profiles associated with different types of breast adipose and their relationship to tumorigenesis Cancer Research
06/04/2012
Abstract 4265: Human prostate mesenchymal stem cells in prostate cancer: Mechanisms of TGF-{beta}1 promoted myofibroblast/CAF differentiation Cancer Research
06/04/2012
Abstract 4264: NF{kappa}B activation in mesenchymal stromal cells induced by leukemia-stroma interaction plays a central role in stroma-mediated chemo-resistance of leukemic cells Cancer Research
06/04/2012
Abstract 4263: Dynamic phenotype switching regulated by epigenetic marks along melanoma genesis Cancer Research
06/04/2012
Abstract 4262: NR2F1 and SOX9 mediate reprogramming of tumor cells into dormancy: Potential role in dormant bone marrow DTCs Cancer Research
06/04/2012
Abstract 4261: Epigenetic reprogramming affects malignant properties of human liver cancer cells Cancer Research
06/04/2012
Abstract 4260: Histone deacetylase 11 (HDAC11) as a novel therapeutic target in the regulation of myeloid-derived suppressor cell (MDSC) Cancer Research
06/04/2012
Abstract 4259: A physiologically relevant 3D cell culture model for screening anti-cancer compounds Cancer Research
06/04/2012
Abstract 4257: Establishment of cancer-tissue originated spheroids (CTOSs) and chemo-sensitivity test for endometrial cancer Cancer Research
06/04/2012
Abstract 4256: Use of short tandem repeat profiling for authentication of human cell lines Cancer Research
06/04/2012
Abstract 4255: Natural product ginger promotes hematopoietic recovery Cancer Research
06/04/2012
Abstract 4254: Human neuroendocrine Bon 1 cells as a three-dimensional model for the study of human neuroendocrine tumor therapy Cancer Research
06/04/2012
Abstract 4253: In vivo activity of small molecule HIF2{alpha} inhibitors Cancer Research
06/04/2012
Abstract 4252: Activated ALK collaborates with MYCN in neuroblastoma pathogenesis Cancer Research
06/04/2012
Abstract 4251: Evaluating novel targeted therapeutic agents in T-cell acute lymphoblastic leukemia using a zebrafish xenotransplantation model Cancer Research
06/04/2012
Abstract 4250: Deficiency of CD109, a negative regulator of TGF-{beta} signaling, leads epidermal hyperplasia and appendage abnormalities in mice Cancer Research
06/04/2012
Abstract 4249: Development of Champions Tumorgraft models in rare cancer types for preclinical investigation and drug discovery Cancer Research
06/04/2012
Abstract 4248: A high-fat diet induces an inflammatory tumor microenvironment in MNU-induced estrogen receptor positive mammary tumors Cancer Research
06/04/2012
Abstract 4246: Long-term primary culture of a mucinous ovarian adenocarcinoma containing CD133 positive cells Cancer Research
06/04/2012
Abstract 4245: Establishment of patients' primary ovarian cancer xenograft models for test of anticancer agents Cancer Research
06/04/2012
Abstract 4244: The role of hypoxia on the tumor-stromal interaction in pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 4242: A humanized tumor mouse model to characterize the interaction of human disseminated cancer cells with the human immune system Cancer Research
06/04/2012
Abstract 4241: Glioma spheroids obtained via ultrasonic aspiration are viable and express stem cell markers: a new tissue resource for glioma research Cancer Research
06/04/2012
Abstract 4240: The translocator protein 18kDa in the morphogenesis of breast epithelial cells in 3D culture Cancer Research
06/04/2012
Abstract 4239: Recapitulation of human tumors in vitro: long-term culture of heterogeneous tumor cell populations in 3-dimensions Cancer Research
06/04/2012
Abstract 4238: Unique ovarian cancer cell line panel: Molecular subtypes and therapy response Cancer Research
06/04/2012
Abstract 4237: Inhibition of prostate cancer associated kinases by Tillandsia recurvata: A Jamaican medicinal plant Cancer Research
06/04/2012
Abstract 4235: Functional assessment of mouse tumor microenvironment following sunitinib treatment using an integrated micro-ultrasound and photoacoustic system Cancer Research
06/04/2012
Abstract 4233A: The opposite effects of doxorubicin on bone marrow cells versus cancer cells in vivo depend on glucosylceramide synthase Cancer Research
06/04/2012
Abstract 4233: The protein ps20 increases resistance to docetaxel in PC3 and LNCAP prostate cancer cell lines Cancer Research
06/04/2012
Abstract 4232: GFP imaging of DNA repair after UV irradiation of cancer cells Cancer Research
06/04/2012
Abstract 4231: Immunohistochemical analysis of claudins expression in penile squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4230: Senescence reversion contributes to acquired drug resistance Cancer Research
06/04/2012
Abstract 4229: The characterization of drug-tolerant cancer cell populations by Colony Lysate Array (CoLA) Cancer Research
06/04/2012
Abstract 4227: Sensitizing resistant ovarian cancer to chemotherapy through inhibition of small GTPases Cancer Research
06/04/2012
Abstract 4226: CD44 increases drug resistance by protecting FBXO21 mediated ubiquitination of P-glycoprotein Cancer Research
06/04/2012
Abstract 4225: Annexin A4 induces chemoresistance for multiple drugs in ovarian clear cell carcinoma Cancer Research
06/04/2012
Abstract 4224: MiR-7 and its novel target regulate sensitivity to microtubule stabilizing agents Cancer Research
06/04/2012
Abstract 4223: Gamma-tocotrienol and simvastatin target TIC and EMT populations in drug-resistant breast cancer Cancer Research
06/04/2012
Abstract 4222: Intercellular transfer between metastatic breast cancer and the endothelium mediated by tunneling nanotubes Cancer Research
06/04/2012
Abstract 4221: Plakophilin 3 (Pkp3) increases oral squamous carcinoma cell-cell adhesion while inhibiting cell motility and proliferation Cancer Research
06/04/2012
Abstract 4220: Beta-catenin signaling initiates the activation of astrocytes and contributes to the pathogenesis of astrocytomas Cancer Research
06/04/2012
Abstract 4219: Claudin-3 and claudin-4 regulate ovarian cancer growth rate and metastatic potential through effect on integrin and {beta}-catenin signaling Cancer Research
06/04/2012
Abstract 4218: Calcitonin receptor increases invasion of prostate cancer cells by activating cAMP-dependent protein kinase (PKA) and promoting phosphorylation of tight junction proteins Cancer Research
06/04/2012
Abstract 4217: Engaging CD151 inhibits cell migration and metastasis through a novel mechanism involving the cell adhesion molecule ALCAM/CD166 Cancer Research
06/04/2012
Abstract 4216: Protein kinase C <= overexpression is associated with loss of membrane-associated E-cadherin and {beta}-catenin in T47D xenograft breast tumors Cancer Research
06/04/2012
Abstract 4215: Integrin-dependent mechanisms for sensitizing melanomas to chemotherapy Cancer Research
06/04/2012
Abstract 4214: Identifying cell surface receptor VAP targets to sensitize melanoma to chemotherapy Cancer Research
06/04/2012
Abstract 4213: Gene expression of hsp27 in renal cell carcinoma and the correlation with tumor progression Cancer Research
06/04/2012
Abstract 4212: Characterization of the gene expression network that underlies cancer cell-platelet interactions and cancer progression Cancer Research
06/04/2012
Abstract 4211: Development of a prognostic gene expression signature for invasive bladder cancer Cancer Research
06/04/2012
Abstract 4210: Association of the 15q25 and 5p15 lung cancer susceptibility regions with gene expression in lung tumor tissue Cancer Research
06/04/2012
Abstract 4209: Hypusine pathway gene expression examined by single molecule RNA fluorescence in situ hybridization (smRNA-FISH) Cancer Research
06/04/2012
Abstract 4208: Post-translational modification of E2F1 in malignant melanoma Cancer Research
06/04/2012
Abstract 4207: CCN5/WISP-2 upregulates p27Kip1 in breast cancer cell lines through AKT/FOXO3a signaling Cancer Research
06/04/2012
Abstract 4206: Identification of transcriptional regulatory motifs that control gene expression in premenopausal women with previous history of breast cancer Cancer Research
06/04/2012
Abstract 4205: Identification of glycine N-methyltransferase-regulated genes in prostate cancer cells Cancer Research
06/04/2012
Abstract 4204: Gene expression changes of DNA repair genes in lymphocytes of breast cancer patients Cancer Research
06/04/2012
Abstract 4202: Genetic re-programming of the AML cell line HL-60 during differentiation: Roles of the EGR/NAB and NR4A transcription factors Cancer Research
06/04/2012
Abstract 4201: Analysis of gene expression profile and signaling networks potentially involved in lymph node metastasis in esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4200: Translation initiation factor eIF3b expression and its role in cancer cell growth and metastases Cancer Research
06/04/2012
Abstract 4198: Transcriptional regulation of breast cancer microRNAs by GATA3 and TFAP2A Cancer Research
06/04/2012
Abstract 4197: Discovering FUS-CHOP targets: A Chip-Seq approach Cancer Research
06/04/2012
Abstract 4196: Identification and investigation of ethnic specific gene expression differences in non-cancerous breast tissue Cancer Research
06/04/2012
Abstract 4195: Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E-BP1 Cancer Research
06/04/2012
Abstract 4194: The superoxide dismutase 1 (SOD1) 3'-UTR maintains high expression of the SOD1 gene in cancer cells Cancer Research
06/04/2012
Abstract 4193: TNF-{alpha} dynamically modulates genome-wide cross-regulation of cRel, {Delta}Np63 and TAp73 promoter binding and gene expression in head and neck cancer: TP53 and NF{kappa}B ChIP-Seq in HNSCC Cancer Research
06/04/2012
Abstract 4192: LIN28 mRNA targets in breast cancer cells Cancer Research
06/04/2012
Abstract 4191: HECT-type ubiquitin ligase ITCH targets lysosomal-associated protein multispanning transmembrane 5 (LAPTM5) and prevents LAPTM5-mediated cell death Cancer Research
06/04/2012
Abstract 4190: Ezrin plays a key role in the regulation of translation in metastatic osteosarcoma Cancer Research
06/04/2012
Abstract 4189: Excess c-Myc loads tissue-specific enhancers in tumor cells Cancer Research
06/04/2012
Abstract 4188: Whole transcriptome analyses of platinum-resistant ovarian cancer cells Cancer Research
06/04/2012
Abstract 4187: A novel genome-wide assay identifies chromatin domains involved in stem cell behavior Cancer Research
06/04/2012
Abstract 4186: An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma Cancer Research
06/04/2012
Abstract 4185: Identifying transcriptional start sites of human microRNAs based on high-throughput sequencing data Cancer Research
06/04/2012
Abstract 4183: Overexpression of PTPN2 promotes lung cancer cell proliferation through ERK activation Cancer Research
06/04/2012
Abstract 4182: Overexpression of Mig-6 suppresses endometrial cancer development and progression in ablation of Pten mice Cancer Research
06/04/2012
Abstract 4181: Absence and/or functional loss of the tumor suppressor Tnk1 is associated with various human neoplasms Cancer Research
06/04/2012
Abstract 4168: Akt pathway in human breast cancer: A comparison between estrogen positive and estrogen negative tumors using reverse phase protein array Cancer Research
06/04/2012
Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance Cancer Research
06/04/2012
Abstract 4166: Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation Cancer Research
06/04/2012
Abstract 4165: Identification of flotillin-1 as a regulator of H-Ras activation in lipid raft Cancer Research
06/04/2012
Abstract 4164: Regulatory mechanism for Ras degradation and its role in the suppression of cellular transformation and tumorigenesis Cancer Research
06/04/2012
Abstract 4163: Determination of synthetic lethal interactions in KRAS oncogene dependent cancer cells reveals novel therapeutic targeting strategies Cancer Research
06/04/2012
Abstract 4162: PTPRO silencing by MAPK pathway in colorectal cancer Cancer Research
06/04/2012
Abstract 4161: Rab25 cooperates with RIN1 to suppress p21 Ras Cancer Research
06/04/2012
Abstract 4160: DEPTOR, an mTOR inhibitor, is a novel substrate of SCF{alpha}TrCP E3 ubiquitin ligase upon S6K1/RSK1 phosphorylation and regulates survival and autophagy Cancer Research
06/04/2012
Abstract 4159: PTEN nucleo-cytoplasmic protein compartmentalization and gene status are correlated with aggressiveness of pulmonary neuroendocrine tumors Cancer Research
06/04/2012
Abstract 4158: MEKK1 regulates DMP1 transcriptional activity via phosphorylation and predicts breast cancer patient outcome Cancer Research
06/04/2012
Abstract 4157: DACH1 Inhibited proliferation and tumor growth of lung adenocarcinoma cells Cancer Research
06/04/2012
Abstract 4156: Interaction between the rabphillin-3A-like gene and phosphorylation of mammalian target of rapamycin (mTOR) in colorectal cancer Cancer Research
06/04/2012
Abstract 4155: Comprehensive glucan profile exploration of mutated K-ras knockdown in colorectal cancer Cancer Research
06/04/2012
Abstract 4154: Exosomal microRNAs: mediators for cell-cell communications Cancer Research
06/04/2012
Abstract 4153: Usefulness of sensitive digital PCR assay to quantify microRNA-34b/c methylation in the circulating serum DNA of malignant mesothelioma patients Cancer Research
06/04/2012
Abstract 4152: Proteomic analysis identifies RAB1A as a novel marker of invasion in neuroblastoma Cancer Research
06/04/2012
Abstract 4151: Real-time imaging of inter-cellular communication via exosomes Cancer Research
06/04/2012
Abstract 4149: Pathway-based serum microRNA profiling and late-stage non-small cell lung cancer survival Cancer Research
06/04/2012
Abstract 4148: MicroRNA biomarkers prognostic for disease-free and overall survival in stage I and II lung adenocarcinoma Cancer Research
06/04/2012
Abstract 4147: Ratio of miR-146b/miR-191 in serum predicts prognosis in surgically resected lung squamous cell carcinomas Cancer Research
06/04/2012
Abstract 4146: The expression of exosomal microRNA in serum of patients with esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4145: Serum miR-21 is a promising biomarker for early detection and prognosis of colorectal cancer Cancer Research
06/04/2012
Abstract 4144: Circulating microRNAs as specific biomarkers for breast cancer Cancer Research
06/04/2012
Abstract 4143: microRNA-874 as a tumor suppressor in maxillary sinus squamous cell carcinoma based on microRNA expression signature Cancer Research
06/04/2012
Abstract 4142: Differential expression of PDCD4 in response to Resveratrol in breast cancer cells Cancer Research
06/04/2012
Abstract 4141: The role of microRNA in gastric cancer Cancer Research
06/04/2012
Abstract 4140: MicroRNA expression in Osteosarcoma: potential role of miR-1 and miR-133b Cancer Research
06/04/2012
Abstract 4139: Clinical evaluation of microRNA expression profiling in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4138: miRNA-362-3p is associated with recurrence of colorectal cancer and targets E2F1, USF2 and PTPN1 Cancer Research
06/04/2012
Abstract 4137: Identification of diagnostic and prognostic miRNAs in lung cancer tissue and serum Cancer Research
06/04/2012
Abstract 4135: Plasma miRNAs as potential predictive/prognostic biomarker for ovarian cancer Cancer Research
06/04/2012
Abstract 4134: miR1288 in colorectal cancers: Altered expression and its clinicopathological significance Cancer Research
06/04/2012
Abstract 4132: MicroRNA-1246 as a novel candidate for a blood-based biomarker in ovarian cancer patients Cancer Research
06/04/2012
Abstract 4131: Serum miRNA profiles of patients with oral cancer and pre-cancer Cancer Research
06/04/2012
Abstract 4130: Bariatric surgery profoundly changes circulating MicroRNA profile in the rat Cancer Research
06/04/2012
Abstract 4129: Green tea polyphenols modulate expression of specific microRNAs for induction of molecular mechanisms of apoptosis in malignant neuroblastoma SH-SY5Y and SK-N-DZ cells Cancer Research
06/04/2012
Abstract 4128: miR203 induces mesenchymal to epithelial transition via repressing SNAI2 and activating P-cadherin in prostate cells Cancer Research
06/04/2012
Abstract 4127: MiR-183/96/182 cluster confers cell motile advantages in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4126: Synergism of polyamine synthesis inhibition and AMP kinase activation on human melanoma proliferation and migration Cancer Research
06/04/2012
Abstract 4125: Suppression of the mevalonate pathway and oncogenic signaling may underlie the tumor-suppressing effects of KLK5 in breast cancer Cancer Research
06/04/2012
Abstract 4124: Activation of AMP-activated protein kinase as a novel mechanism of resistance to EGFR-targeted therapy Cancer Research
06/04/2012
Abstract 4123: Cholesterol and breast cancer Cancer Research
06/04/2012
Abstract 4122: Induction of steroid sulfatase expression by bacterial lipopolysaccharides in human prostate cancer cells: Possible role of STS in tumor cell migration Cancer Research
06/04/2012
Abstract 4121: Glycine N-methyltransferase deficiency affects hepatic cholesterol homeostasis and steatosis-associated inflammation Cancer Research
06/04/2012
Abstract 4119: High-throughput proteomics reveals that enzymes of the ketogenic pathway are upregulated during prostate cancer progression Cancer Research
06/04/2012
Abstract 4118: Hypoxia affects the metabolic activation and detoxification of the environmental mutagen benzo(a)pyrene Cancer Research
06/04/2012
Abstract 4117: Increased pancreatic adipocyte hypertrophy in EL-Kras/PEDF null mice with versus without pancreatic cancer Cancer Research
06/04/2012
Abstract 4116: Mammary adipocyte-specific metabolic alterations are associated with paracrine effects on mammary tumorigenesis Cancer Research
06/04/2012
Abstract 4115: Depletion of unsaturated fatty acids by stearoyl-coA desaturase inhibition results in endoplasmic reticulum stress-mediated tumor cell death Cancer Research
06/04/2012
Abstract 4114: Dual cytoprotective and cytotoxic functions of autophagy in the response of breast tumor cells to radiation and in radiosensitization by vitamin D3 Cancer Research
06/04/2012
Abstract 4113: Combination of LC3 II shRNA and genistein completely inhibited rapamycin-induced autophagy and promoted apoptosis in human malignant neuroblastoma cell lines Cancer Research
06/04/2012
Abstract 4112: Prognostic impact of autophagic markers LC3, Beclin 1 and p62/sequestosome 1 in colon carcinomas from patients treated in 5-FU-based adjuvant therapy trials Cancer Research
06/04/2012
Abstract 4110: Measurement of autophagy in sensitive versus resistant breast cancer cells Cancer Research
06/04/2012
Abstract 4109: The unfolded protein response promotes tolerance to extreme hypoxia through autophagy dependent maintenance of cellular metabolism Cancer Research
06/04/2012
Abstract 4108: The lichen compound usnic acid disturbs mitochondrial and lysosomal function by proton shuttling Cancer Research
06/04/2012
Abstract 4107: Possible role of autophagy inhibition in hypoxia-induced chemoresistance of pancreatic cancer cells Cancer Research
06/04/2012
Abstract 4106: Sirt3 controls the switch between mitophagy and apoptosis in tumor cells Cancer Research
06/04/2012
Abstract 4105: Assessment of autophagosome formation in primary cells by lentiviral delivery of fluorescent protein-tagged LC3 Cancer Research
06/04/2012
Abstract 4104: Moderate calorie restriction activates autophagy during tumor growth suppression Cancer Research
06/04/2012
Abstract 4103: Hepatocellular carcinoma-specific isoforms of methylated DNA-binding protein 2 and their therapeutic and diagnostic potential Cancer Research
06/04/2012
Abstract 4102: Histone deacetylase inhibitor, vorinostat, decreases transcription of survivin and is an enhancer of gemcitabine therapy for resistant pancreatic tumors Cancer Research
06/04/2012
Abstract 4101: Prognostic significance of LINE-1 mathylation level in gastric cancer Cancer Research
06/04/2012
Abstract 4100: Aberrant methylation of the PTPRO gene in peripheral blood as a potential biomarker in esophageal squamous cell carcinoma patients Cancer Research
06/04/2012
Abstract 4099: Utilization of methylation levels across the H19 and IGF2 genes as a predictive marker for various types of cancer Cancer Research
06/04/2012
Abstract 4098: COX-2 expression in human pancreatic cancer cells is associated with an epithelial phenotype Cancer Research
06/04/2012
Abstract 4097: Integrative analysis of epigenetic and transcriptional alterations in head and neck squamous cell carcinomas Cancer Research
06/04/2012
Abstract 4096: Correction of metabolically sensitive histone epigenetic marks mediates the drug sensitivity of MDA-MB-231 human breast cancer cells Cancer Research
06/04/2012
Abstract 4095: Stimulation of blood based biomarker release in primary tumor models of the head and neck Cancer Research
06/04/2012
Abstract 4094: Identification of novel breast cancer methylation biomarkers by global demethylation, cDNA microarray, and quantitative methylation analysis Cancer Research
06/04/2012
Abstract 4093: Investigating a role for menin and MLL-AF9 in suppressing C/EBP{beta}-mediated mixed lineage leukemia cell differentiation Cancer Research
06/04/2012
Abstract 4092: Cancer-type regulation of MIG-6 expression by 5-Aza-2'-deoxycytidine and Trichostatin A Cancer Research
06/04/2012
Abstract 4091: Identification of epigenetic alterations associated with tumor progression and cancer metastasis Cancer Research
06/04/2012
Abstract 4090: Epigenetic profiling identifies differentially methylated loci in metastatic vs. non-metastatic primary squamous and basal cell skin cancers Cancer Research
06/04/2012
Abstract 4089: Identification of a DNA methylation marker to detect the presence of lymph node metastases of gastric cancers Cancer Research
06/04/2012
Abstract 4088: Cotreatment with decitabine and paclitaxel is affected by the re-expression of drug-metabolising enzymes Cancer Research
06/04/2012
Abstract 4087: Microbiomic subprofiles and MDR1 promoter methylation in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4086: Location matters: The impact of the location of CpG sites on the specificity of methylation biomarkers for HCC Cancer Research
06/04/2012
Abstract 4085: The roles of HDACs in chromatin remodelling and response to chemotherapy in cancer Cancer Research
06/04/2012
Abstract 4084: Exploring predictive biomarkers of in vitro sensitivity to azacitidine in breast cancer Cancer Research
06/04/2012
Abstract 4083: Increased DNA methyltransferase activity and DNA methylation following epidermal growth factor stimulation in ovarian cancer cells Cancer Research
06/04/2012
Abstract 4082: Global miRNA expression changes induced by HDAC-42 and 5-azaCdr in lung cancer cells Cancer Research
06/04/2012
Abstract 4081: In vivo effects of decitabine on global gene expression profiles in tumors from patients with platinum-resistant ovarian cancer Cancer Research
06/04/2012
Abstract 4080: 5-Azacitydine augments the anti-glioma efficacy of Herpes-based oncolytic virotherapy Cancer Research
06/04/2012
Abstract 4079: Proanthocyanidins reactivate silenced tumor suppressor genes p16INK4a and Cip1/p21 by reducing DNA methylation and increasing histone acetylation in human non-small cell lung cancer cells Cancer Research
06/04/2012
Abstract 4077: Chemosensitizing effects of the novel, small molecule DNA methylation inhibitor SGI-110 in ovarian cancer Cancer Research
06/04/2012
Abstract 4076: SGI-110, a novel subcutaneous (SQ) second generation DNA hypomethylating agent achieves improved pharmacodynamics (PD), safety and pharmacokinetics (PK) in comparison to IV decitabine in a non-human primate in vivo study Cancer Research
06/04/2012
Abstract 4075: Aerosol azacytidine inhibits the orthotopic lung cancer in mice by its demethylation function but not cytotoxic effect Cancer Research
06/04/2012
Abstract 4074: Prostaglandin E2 promotes intestinal tumor growth via DNA methylation Cancer Research
06/04/2012
Abstract 4073: Comprehensive cell health analysis on a novel multi-parametric cell analyzer Cancer Research
06/04/2012
Abstract 4071: PAXgene Tissue: A new tissue fixation technology for simultaneous preservation of morphology and nucleic acids Cancer Research
06/04/2012
Abstract 4069: Determination of single cell surface protein expression using a tagless microfluidic method Cancer Research
06/04/2012
Abstract 4066: Early assessment of the XL184 treatment by Diffusion-Weighted MRI in metastatic prostate cancer to the bone murine model Cancer Research
06/04/2012
Abstract 4065: A simple biological imaging system for detecting adenovirus receptor expression in tumor cells using a telomerase-specific replication-competent adenovirus Cancer Research
06/04/2012
Abstract 4064: 3-D imaging of human colorectal cancer tissues with optical clearing: Spatial analysis of the tumor vasculature through transparent specimens Cancer Research
06/04/2012
Abstract 4063: Image-guided fluorescent endomicroscopy of glioblastoma with SVV-GFP viral labeling Cancer Research
06/04/2012
Abstract 4062: A kinetic live-cell imaging approach to measuring cytotoxicity in vitro Cancer Research
06/04/2012
Abstract 4061: Computer-assisted Gleason grading of prostate cancer: Two novel approaches using nuclear shape and texture feature to classify pathologic Gleason grade patterns 3 and 4 Cancer Research
06/04/2012
Abstract 4060: Use of small animal MRI and cone-beam CT for image-guided radiotherapy of orthotopic tumors in mice Cancer Research
06/04/2012
Abstract 4059: Development of a point-of-care device for circulating tumor cell/cluster detection Cancer Research
06/04/2012
Abstract 4058: Multispectral imaging of mismatch repair proteins in colorectal cancers and tumor cells isolated from blood Cancer Research
06/04/2012
Abstract 4057: Quantitative assessment of 3D nuclear architecture in colon epithelial cells by micro-optical computed tomography Cancer Research
06/04/2012
Abstract 4056: Gaussia luciferase complementation demonstrates that secreted CXCL12 (SDF-1) forms dimer under physiologic conditions Cancer Research
06/04/2012
Abstract 4054: Assessment of the progression of lymph node metastases using three-dimensional optical coherence tomography (OCT) Cancer Research
06/04/2012
Abstract 4053: A label-free spectroscopic signature associated with hormone sensitivity in 3D co-culture models of breast cancer Cancer Research
06/04/2012
Abstract 4052: Highlighting intratumoral heterogeneity and peritumoral areas in human melanoma biopsies by infrared spectral microimaging Cancer Research
06/04/2012
Abstract 4051: A mouse model of head and neck cancer with infrared-based molecular imaging Cancer Research
06/04/2012
Abstract 4049: Early prediction of response to targeted drugs treatment in malignant lymphoma and sarcoma using in vivo proliferation marker 18F-FLT Cancer Research
06/04/2012
Abstract 4048: Multiphoton tomographic imaging is an effective optical biopsy tool for detecting gastrointestinal inflammation and neoplasia Cancer Research
06/04/2012
Abstract 4047: Introducing a novel acoustic imaging tool for breast cancer detection Cancer Research
06/04/2012
Abstract 4046: Kinetic quantification of caspase-3/7 mediated apoptosis using live-cell imaging Cancer Research
06/04/2012
Abstract 4045: Intragenic ATM methylation in peripheral blood DNA as a biomarker of breast cancer risk Cancer Research
06/04/2012
Abstract 4044: Epigenetic repression of RARRES1 is mediated by methylation of a critical proximal promoter and a loss of CTCF binding Cancer Research
06/04/2012
Abstract 4043: Loss of imprinting of KCNK9 in breast cancer Cancer Research
06/04/2012
Abstract 4042: Loss of imprinting at the 14q32 locus contributes to osteosarcoma Cancer Research
06/04/2012
Abstract 4041: Identification of GNG7 as an epigenetically silenced gene in head and neck cancer by gene expression profiling Cancer Research
06/04/2012
Abstract 4040: Silence of miR-203 by promoter methylation in endometrial cancer Cancer Research
06/04/2012
Abstract 4039: Loss of imprinting in PEG3, MEST and ARHI/DIRAS3 in invasive breast cancer Cancer Research
06/04/2012
Abstract 4038: CpG hypermethylation of p16 and BDNF associate with distant metastasis and survival of head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4037: Downregulation of ZNF516 and INTS1 is related with promoter methylation in cervical uterine cancer cell lines Cancer Research
06/04/2012
Abstract 4036: Frequent downregulation of the transcription factor Foxa2 in lung cancer through epigenetic silencing Cancer Research
06/04/2012
Abstract 4035: Inactivation of the putative tumor suppressor gene AGTR1 by promoter hypermethylation in primary human cancer Cancer Research
06/04/2012
Abstract 4034: The role of CYP33 in MLL target gene repression Cancer Research
06/04/2012
Abstract 4033: A20 gene promoter methylation confers resistance to colorectal carcinoma cell lines Cancer Research
06/04/2012
Abstract 4032: Consequences of NEIL1 promoter hypermethylation in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4031: MGMT methylation based outcome prediction is associated with two CpG regions separated by a prediction minimum centred at the initiation start site Cancer Research
06/04/2012
Abstract 4030: Wnt antagonist SFRP4 acts as a tumor suppressor gene in gastric carcinomas Cancer Research
06/04/2012
Abstract 4029: Enhanced chemosensitivity of estrogen receptor-{alpha} (ER{alpha})-negative breast cancer through soybean genistein-induced epigenetic reactivation of ER{alpha} Cancer Research
06/04/2012
Abstract 4028: Therapeutic relevance of two novel cancer candidate genes, RASAL2 and NENF, activated by DNA hypomethylation Cancer Research
06/04/2012
Abstract 4027: Regulation of p16INK4A and TGF-beta by DNA hydroxymethylation in glioblastoma multiforme Cancer Research
06/04/2012
Abstract 4026: Epigenetic biomarker discovery and validation for diagnosis and therapeutic intervention for hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4025: Evaluation of homologous recombination (HR) genes in myeloproliferative neoplasms (MPNs) suggests BRCA1 as a potential biomarker for sensitivity to poly (ADP-ribose) polymerase (PARP) inhibition and disease progression Cancer Research
06/04/2012
Abstract 4024: Aberrant DNA methylation of Shisa3 is a novel prognostic biomarker for colorectal cancer Cancer Research
06/04/2012
Abstract 4180: The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Hippo tumor suppressor pathway Cancer Research
06/04/2012
Abstract 4179: Loss of Hsulf-1 promotes chemoresistance and tumorigenecity in ovarian cancer Cancer Research
06/04/2012
Abstract 4178: Tcl1 enhances keratinocytes' survival/proliferation by promoting erk and jnk/sap phosphorylation at the expense of p38 and by controlling c-fos expression through miR-29b and miR-181a-1 Cancer Research
06/04/2012
Abstract 4177: Synergistic role of ecdysoneless with oncogenic Ras in transformation of human mammary epithelial cells Cancer Research
06/04/2012
Abstract 4176: Activated NRAS mediates self-renewal capacity in AML Cancer Research
06/04/2012
Abstract 4175: Reactive oxygen species-dependent ERK and JNK activation is important to docasahexaenoic acid-induced cell cytotoxicity in human ovarian cancer cells Cancer Research
06/04/2012
Abstract 4174: Identification of PRPF4 as a novel cancer promoter through AKT signaling in lung cancer Cancer Research
06/04/2012
Abstract 4173: IKBKE/IKK{alpha} is a prognostic marker and is required for KRAS-driven tumorigenecity in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4172: Identification of a low PTEN / high PI3K{alpha} expressing subset of squamous non-small-cell lung cancer (NSCLC) Cancer Research
06/04/2012
Abstract 4171: Functional relevance of particular residues within the BRAF kinase domain in anaplastic thyroid carcinoma Cancer Research
06/04/2012
Abstract 4170: Mutation and chemosensitivity profiling of 18 human melanoma cell lines Cancer Research
06/04/2012
Abstract 3843: Targeting FACT complex suppresses mammary tumorigenesis in Her2/neu transgenic mice Cancer Research
06/04/2012
Abstract 3842: Methylseleninic acid, a novel potent and selective mutant-p53-rescue drug, reactivates mutant p53 by thiol modification Cancer Research
06/04/2012
Abstract 3841: HIF-143, a novel inhibitor of complex III, inhibits pancreatic cancer growth by suppressing reactive oxygen species production and epidermal growth factor signal Cancer Research
06/04/2012
Abstract 3840: Evaluation of the synergetic effect of a combination of dehydroxymethylepoxyquinomicin and gemcitabine on liver metastasis of pancreatic cancer Cancer Research
06/04/2012
Abstract 3839: Nuclear export (karyopherin) inhibitors: A novel therapeutic strategy for treating Philadelphia-positive (Ph+) acute leukemias Cancer Research
06/04/2012
Abstract 3838: NKP-2235 exhibits a novel pattern of cytotoxicity with synergism across a broad range of antitumor agents demonstrated in multiple tumor types Cancer Research
06/04/2012
Abstract 3836: Enhancement of doxorubicin cytotoxicity in breast cancer by NIM811, A non-immunosuppressive cyclosporine A analog Cancer Research
06/04/2012
Abstract 3835: Identification and characterization of inhibitors of 5'-nucleotidase cN-II issued from virtual screening Cancer Research
06/04/2012
Abstract 3834: JKA97, a novel anti-cancer candidate, induces G1 arrest via up-regulation of p21 in a p53-independent manner Cancer Research
06/04/2012
Abstract 3833: Ceramide/tamoxifen nanoliposomal combination - A promising strategy for treatment of chemoresistant breast cancer Cancer Research
06/04/2012
Abstract 3832: Tolerance of oral lipoid acid and hydroxycitrate combination in cancer patients: first approach of the cancer metabolism research group Cancer Research
06/04/2012
Abstract 3831: 131I-CLR1404 and CLR1404: Broad spectrum, cancer-targeted molecular radio- and chemotherapeutic phospholipid ether analogs Cancer Research
06/04/2012
Abstract 3830: Novel small molecule translation inhibitors with safety and efficacy in triple negative breast cancer (TNBC) animal models Cancer Research
06/04/2012
Abstract 3829: Inhibition of breast cancer metastasis by deguelin in an experimental model Cancer Research
06/04/2012
Abstract 3828: Potent curcumin analogues inhibit pancreatic cancer cell growth and angiogenesis Cancer Research
06/04/2012
Abstract 3823: 2-Methyl-6-substituted pyrrolo[2,3-d]pyrimidine classical antifolates as selective folate receptor substrates, glycinamide ribonucleotide formyltransferase inhibitors and antitumor agents Cancer Research
06/04/2012
Abstract 3822: A tumor-targeted 5-pyrrolo[2,3-d]pyrimidine antifolate is a selective substrate for folate receptor <= and potent inhibitor of 5-amino-4-carboxamide formyltransferase in de novo purine nucleotide biosynthesis Cancer Research
06/04/2012
Abstract 3821: Interaction and cross-resistance of cisplatin and pemetrexed in malignant pleural mesothelioma cell lines Cancer Research
06/04/2012
Abstract 3820: Reduced migration and enhanced killing of glioblastoma multiforme by mefloquine via alteration of sphingolipid levels Cancer Research
06/04/2012
Abstract 3819: COX-2 inhibition with apricoxib drives mesenchymal to epithelial transition and synergizes with anti-VEGF therapy Cancer Research
06/04/2012
Abstract 3818: Arsenic hexaoxide (As4O6) shows anticancer effects on human colon cancer cells in vitro and in vivo Cancer Research
06/04/2012
Abstract 3817: Nitric oxide-donating aspirin induces G2/M phase cell cycle arrest in human cancer cells by regulating phase transition proteins Cancer Research
06/04/2012
Abstract 3816: Comparative cellular effects of 4-phenyl-3-butenoic acid and suberoylanilide acid in tumorigenic and non-tumorigenic cells Cancer Research
06/04/2012
Abstract 3815: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action Cancer Research
06/04/2012
Abstract 3814: Combination of selective modular of the glucocorticoid receptor (SEGRA) with proteasome inhibitors as a novel strategy for chemotherapy of hematologic malignancies Cancer Research
06/04/2012
Abstract 3813: DNA polymerase eta and a novel anticancer selenophene compound Cancer Research
06/04/2012
Abstract 3812: Deguelin as a novel therapeutic agent for Herceptin resistant breast cancers Cancer Research
06/04/2012
Abstract 3811: The receptors-independent anti-cancer effect of anandamide in head and neck squamous cell carcinoma cells Cancer Research
06/04/2012
Abstract 3810: Ciclopirox olamine downregulates Cdc25A expression in tumor cells Cancer Research
06/04/2012
Abstract 3809: Effects of honokiol on UACC-62 and SKMEL-2 melanoma cell lines Cancer Research
06/04/2012
Abstract 3808: Tetrandrine blocks cell cycle progression and promotes growth arrest in prostate cancer cells by up-regulating CDK inhibitors (p21 and p27) and suppressing cyclin expression. Cancer Research
06/04/2012
Abstract 3807: Regulation of pancreatic, gliosarcoma and non-small cell lung cancer via CPI-613, a novel anticancer therapeutic agent Cancer Research
06/04/2012
Abstract 3806: Suppression of prostate cancer growth and invasion by a triphenyl ethylene compound ormeloxifene Cancer Research
06/04/2012
Abstract 3805: Identification of a distinctive pattern of lipid composition in Irvalec(R) resistant tumor cells Cancer Research
06/04/2012
Abstract 3804: Molecular changes induced by the curcumin biphenyl analogue D6 in melanoma cells Cancer Research
06/04/2012
Abstract 3803: Anti-cancer activity of Capridine, a novel nitroacridine chemotherapeutic, in glioblastoma Cancer Research
06/04/2012
Abstract 3802: Effect of CS-7017, a selective PPAR{delta} agonist, on the TGF{beta}/Smad-mediated enhanced cell motility of EGFR-tyrosine kinase inhibitor-resistant non-small cell lung cancer cells Cancer Research
06/04/2012
Abstract 3801: Prostate cancer cells are selectively targeted by zinc-sequestration chemotherapy Cancer Research
06/04/2012
Abstract 3800: Nitric oxide acts a promoter of the enhanced permeation and retention effect in a xenograft pancreatic carcinoma model Cancer Research
06/04/2012
Abstract 3799: Polyamine Transport System (PTS) activity and hijacking in cancer cells: New option in Head and Neck tumors treatment with the polyamine-containing drug candidate F14512 Cancer Research
06/04/2012
Abstract 3798: Cryptotanshinone inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3/ERK and small GTPase pathways Cancer Research
06/04/2012
Abstract 3797: Hyperphosphorylation and desumoylation of RanGAP1{middle dot}SUMO1 Cancer Research
06/04/2012
Abstract 3795: BubR1 function is required for the antiproliferative activity of the novel microtubule-targeting drug BAL27862 (active moiety of the prodrug BAL101553) Cancer Research
06/04/2012
Abstract 3794: Inhibition of prostate cancer bone metastases by the dickkopf-1 neutralizing antibody BHQ880 Cancer Research
06/04/2012
Abstract 3793: Characterization of the mechanism of action of a novel small molecule inhibitor of HSP70 Cancer Research
06/04/2012
Abstract 3792: Population Pharmacokinetic (PPK) modeling of ProLindac&trade; (AP5346), a nanopolymer prodrug of diaminocyclohexane (DACH)-platinum (Pt) in recurrent advanced ovarian cancer (AOC) patients Cancer Research
06/04/2012
Abstract 3791: Milk thistle as an inhibitor of PXR-mediated CYP3A4 induction Cancer Research
06/04/2012
Abstract 3790: Preclinical profile of LGX818: A potent and selective RAF kinase inhibitor Cancer Research
06/04/2012
Abstract 3789: Development of an animal model for microdialysis sampling of pons and cerebral cortex in rhesus macaques Cancer Research
06/04/2012
Abstract 3788: Routine micro-sampling and LC-MS/MS quantitation for PK and PK/PD determination in mice Cancer Research
06/04/2012
Abstract 3787: Pharmacokinetics and pharmacodynamics of AV-203, a humanized anti-ERBB3 antibody Cancer Research
06/04/2012
Abstract 3786: Physiologically based pharmacokinetic model of CFAK-C4 disposition in mice for understanding its anti-tumor efficacy Cancer Research
06/04/2012
Abstract 3785: Human pharmacokinetics (PK) of selected tyrosine kinase inhibitors (TKI) in relation to transport characteristics in a polarized gut epithelium model system Cancer Research
06/04/2012
Abstract 3784: AME-133v, a humanized, Fc-engineered anti-CD20 monoclonal antibody, demonstrates greater B cell depletion than Rituxan in vitro Cancer Research
06/04/2012
Abstract 3783: Pharmacokinetics and CNS biodistribution of WP1066, a novel small molecule inhibitor of STAT-3 phosphorylation Cancer Research
06/04/2012
Abstract 3782: Plasma pharmacokinetics of fluorodeoxycytidine, downstream metabolites, and tetrahydrouridine after combined administration to cynomolgus monkeys Cancer Research
06/04/2012
Abstract 3781: Pharmacokinetics of endoxifen and tamoxifen in female mice: Implications for comparative in vivo activity studies Cancer Research
06/04/2012
Abstract 3780: GEP01: Population pharmacokinetic-pharmacodynamic (PK/PD) model for neutropenia of lapatinib and iv vinorelbine in the treatment of HER2-positive locally advanced or metastatic breast cancer Cancer Research
06/04/2012
Abstract 3779: Novel oral gallium compounds as modulators of cancer-related accelerated bone loss Cancer Research
06/04/2012
Abstract 3778: Pharmacokinetic, safety and efficacy of high dose simvastatin in refractory and relapsed chronic lymphocytic leukemia (CLL) patients Cancer Research
06/04/2012
Abstract 3777: Applying mechanistic pharmacokinetic-pharmacodynamic models (PKPD) to describe the growth and inhibition of xenograft tumors in rats and mice by targeted anticancer agents Cancer Research
06/04/2012
Abstract 3776: Antitumor response to inotuzumab ozogamicin (INO) in patients with refractory or relapsed indolent B-cell non-Hodgkin's lymphomas (NHL): Pharmacokinetic-pharmacodynamic (PK-PD) modeling and interim results from a phase II study Cancer Research
06/04/2012
Abstract 3775: Pharmacokinetic (PK) / pharmacodynamic (PD) and efficacy relationship of selective inhibitors of nuclear export (KPT-SINE) Cancer Research
06/04/2012
Abstract 3774: Using hybrid population pharmacokinetic (PK)- scaled efficacy exponential tumor model to determine possible efficacious dose for an anticancer agent Cancer Research
06/04/2012
Abstract 3773: Absolute bioavailability of BRAF inhibitor GSK2118436: Use of a microtracer study in patients with cancer Cancer Research
06/04/2012
Abstract 3772: Passive tumor targeting with drug-loaded liposomes: Experimental evidences that size does matter Cancer Research
06/04/2012
Abstract 3771: Capecitabine pharmacokinetics and efficacy in spontaneous tumors occurring in a genetically engineered mouse model (GEMM) of pancreatic cancer Cancer Research
06/04/2012
Abstract 3770: PK/PD/Efficacy characterization of AZ285, a selective CK2 kinase inhibitor Cancer Research
06/04/2012
Abstract 3769: Metabolic activation of batracylin and N-acetylbatracylin to reactive metabolites that bind protein and DNA: Possible role in toxicity Cancer Research
06/04/2012
Abstract 3768: Evaluating the effects of bortezomib (Velcade(R)) on the pharmacokinetics (PK) of pegylated liposomal doxorubicin (Doxil(R), PLD) Cancer Research
06/04/2012
Abstract 3767: Use of pharmacokinetic-pharmacodynamic modeling to characterize platelet response following inotuzumab ozogamicin treatment in patients with follicular or diffuse large B-cell non-Hodgkin's lymphoma Cancer Research
06/04/2012
Abstract 3766: Effects of a high-fat meal on the pharmacokinetics of orally administered GSK2118436 in patients with BRAF mutation-positive tumors Cancer Research
06/04/2012
Abstract 3765: Discovery and biological characterization of CX-8184, a potent inhibitor of protein kinase CK2 Cancer Research
06/04/2012
Abstract 3764: SC-1, a sorafenib derivative, induces apoptosis in epidermal growth factor receptor wild type non-small cell lung cancer through the inhibition of signal transducers and activators of transcription 3 Cancer Research
06/04/2012
Abstract 3763: Treatment of soft tissue sarcoma cells by EGFR and/or STAT3 inhibitors Cancer Research
06/04/2012
Abstract 3762: Second generation PIM inhibitors exhibit improved activity in solid tumor models Cancer Research
06/04/2012
Abstract 3761: Efficacy of the ATP-competitive mTOR inhibitor AZD8055 in PTEN-wild type cancer cells Cancer Research
06/04/2012
Abstract 3760: A novel PKC-iota inhibitor, ICA-1 abrogates cell proliferation in breast cancer Cancer Research
06/04/2012
Abstract 3759: P7170, a novel inhibitor of phosphoinositide 3-kinase (PI3K)-mammalian target of Rapamycin (mTOR) and activin receptor-like kinase 1 (ALK1) as a new therapeutic option for Kras mutated non small cell lung cancer (NSCLC) Cancer Research
06/04/2012
Abstract 3758: Activity of AZD4547, a potent and selective FGF-receptor inhibitor, alone and in combination with chemotherapy in standard xenograft and human primary explant models of FGF-receptor 2 amplified gastric cancer Cancer Research
06/04/2012
Abstract 3757: CR8, a novel CDK inhibitor, enhances vandetanib activity in a human medullary thyroid carcinoma model Cancer Research
06/04/2012
Abstract 3755: Antitumor activity of CEP-32496, a novel orally active BRAFV600E inhibitor, in a panel of Champions TumorGraft models of melanoma and colorectal cancer with B-Raf V600E mutations Cancer Research
06/04/2012
Abstract 3754: Characterization of NMS-P285, a new highly selective and potent BRAF inhibitor Cancer Research
06/04/2012
Abstract 3752: Nanoparticles delivery of a novel AKT/PDK1 inhibitor inhibits pancreatic cancer tumor growth Cancer Research
06/04/2012
Abstract 3751: In vitro and in vivo pharmacological profile of BAY 1001931, a novel highly potent allosteric AKT1/2 inhibitor Cancer Research
06/04/2012
Abstract 3750: The novel Akt inhibitor MK-2206, is cytotoxic in T-cell acute lymphoblastic leukemia: Therapeutic implications Cancer Research
06/04/2012
Abstract 3749: Single agent activity of PIK3CA inhibitor BYL719 in a broad cancer cell line panel Cancer Research
06/04/2012
Abstract 3748: NVP-BYL719, a novel PI3Kalpha selective inhibitor with all the characteristics required for clinical development as an anti-cancer agent Cancer Research
06/04/2012
Abstract 3747: Pulsatilla saponin D suppresses angiogenesis and induces apoptosis via inhibition of PI3K/Akt/mTOR signaling pathway in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 3745: The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKcs-mediated DNA damage responses Cancer Research
06/04/2012
Abstract 3744: Antitumor activity of CUDC-907, a dual PI3K and HDAC inhibitor, in hematological cancer models Cancer Research
06/04/2012
Abstract 3743: NVP-BYL719, a selective inhibitor of the class Ia PI3K isoform alpha impairs angiogenesis and microvascular permeability. Cancer Research
06/04/2012
Abstract 3742: P7170: A potent and oral phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) and activin receptor-like kinase 1 (ALK1) inhibitor with anti-tumor and anti-angiogenic activity Cancer Research
06/04/2012
Abstract 3741: Inhibition of PI3K{alpha} kinase by a selective small molecule inhibitor suppresses B-cell proliferation and leukemic cell growth Cancer Research
06/04/2012
Abstract 3740: NVP-BEZ235, a dual PI3K/ mTOR inhibitor, suppress tumorigenicity of ovarian clear cell carcinoma cells. Cancer Research
06/04/2012
Abstract 3739: TAK-733, an investigational, selective MEK1/2 inhibitor, in combination with alisertib (MLN8237), an investigational, selective Aurora A kinase inhibitor is tolerated and results in additive to synergistic antitumor activity: Results from In Vivo Studies Cancer Research
06/04/2012
Abstract 3738: A rationale for combining the targeted investigational agents TAK-733, a MEK1/2 inhibitor, with alisertib (MLN8237), an Aurora A kinase inhibitor, for cancer therapy Cancer Research
06/04/2012
Abstract 3737: The PI3K/mTOR inhibitor PWT33597 regresses 786-0 renal xenografts Cancer Research
06/04/2012
Abstract 3736: The mTOR inhibitor, RAD001, displays higher cytotoxicity in leukemias with hyperactivated PI3K/AKT/mTOR pathway Cancer Research
06/04/2012
Abstract 3735: Increased efficacy with use of combination therapy of API 31510 and gemcitabine in the treatment of pancreatic cancer Cancer Research
06/04/2012
Abstract 3734: Paclitaxel disrupts polarized entry of membrane permeable C6 ceramide into ovarian cancer cells resulting in synchronous induction of cell death Cancer Research
06/04/2012
Abstract 3733: Combined effect of linalool as component of Humulus lupulus on doxorubicin-induced antitumor activity Cancer Research
06/04/2012
Abstract 3732: New aspirin analogs for targeted therapy of ER+ breast cancers with activated NFkB inflammatory pathway Cancer Research
06/04/2012
Abstract 3731: Directing combinatorial therapy of breast cancer using signaling pathway predictors Cancer Research
06/04/2012
Abstract 3730: Cisplatin treatment enhancement with acetaminophen in a model of human medulloblastoma in nude rats Cancer Research
06/04/2012
Abstract 3729: Resveratrol enhances the anti-proliferative response of zinc by increasing zinc-transporter protein ZIP1 in prostate cancer cells: A novel combinatorial approach for prostate cancer management Cancer Research
06/04/2012
Abstract 3727: Targeting autotaxin to reduce chemotherapy resistance in ovarian cancer Cancer Research
06/04/2012
Abstract 3726: Allyl isothiocyanate (AITC), a naturally occurring compound, combined with platinum-based therapies enhances apoptosis in vitro, and inhibits lung tumor growth in vivo Cancer Research
06/04/2012
Abstract 3725: Combined cytotoxic effects of volasertib and cisplatin in urothelial carcinoma cells Cancer Research
06/04/2012
Abstract 3724: Wogonin enhances tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo through H2O2-mediated downregulation of X-linked inhibitor of apoptosis protein and cellular inhibitor of apoptosis protein 1 and 2 Cancer Research
06/04/2012
Abstract 3722: Quinacrine and sorafenib combination as potential therapy for anaplastic thyroid cancer Cancer Research
06/04/2012
Abstract 3721: Combination of temozolomide and O6- benzylguanine inhibits breast cancer growth Cancer Research
06/04/2012
Abstract 3720: Combination treatment with hypoxia-activated prodrug TH-302 and the mTOR inhibitor everolimus results in enhanced antitumor efficacy in preclinical models Cancer Research
06/04/2012
Abstract 3719: Simultaneous targeting of ER-stress and PI3K/AKT pathways as novel anticancer and chemosensitization approach against castration resistant prostate cancer Cancer Research
06/04/2012
Abstract 3718: Oncolytic reovirus synergizes with bortezomib and dexamethasone in overcoming therapy resistance of multiple myeloma Cancer Research
06/04/2012
Abstract 3715: EP-100 syndergizes with paclitaxel in ovarian, breast and prostate cancer cell lines Cancer Research
06/04/2012
Abstract 3714: Characterization of a selective focal adhesion kinase (FAK) inhibitor in a panel of glioblastoma cell lines identify rational drug-drug combination strategies Cancer Research
06/04/2012
Abstract 3713: Comparison of endpoints and data analysis methods for exposure of human tumor cells to dasatinib (NSC732517) and 6-MP (NSC755) in culture Cancer Research
06/04/2012
Abstract 3712: Gap junction enhancer potentiates cytotoxic effect of cisplatin Cancer Research
06/04/2012
Abstract 3710: Preclinical dose scheduling studies of LOR-253, a novel anticancer drug, in combination with chemotherapeutics in lung and colon cancers Cancer Research
06/04/2012
Abstract 3989: IQGAP2 inhibits cell proliferation and migration in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 3988: Aberrant NFKBIA expression in lung adenocarcinomas arising from never smokers Cancer Research
06/04/2012
Abstract 3987: Merlin is a negative regulator of human melanoma Cancer Research
06/04/2012
Abstract 3986: Science Exchange: An integrated platform for experiment outsourcing Cancer Research
06/04/2012
Abstract 3985: Senescent cells in growing tumors: population dynamics and cancer stem cells Cancer Research
06/04/2012
Abstract 3983: Evaluation of data compression strategies for genetic variation calling using next generation sequencing data in normal and tumor samples Cancer Research
06/04/2012
Abstract 3982: Cancer genome sequencing analysis, storage, discovery and delivery Cancer Research
06/04/2012
Abstract 3981: Evaluation of mutation detection sensitivity in exome sequencing and other genotyping platforms Cancer Research
06/04/2012
Abstract 3980: Computational analysis of paclitaxel-induced tumor priming that leads to enhanced deposition and efficacy nanoparticulate doxorubicin Cancer Research
06/04/2012
Abstract 3979: Ethnic polymorphisms in the GGAA microsatellite response element of key Ewing's sarcoma EWS/FLI-target genes Cancer Research
06/04/2012
Abstract 3977: Meta-analysis of posttranslational modifications in cancer Cancer Research
06/04/2012
Abstract 3976: NetGestalt: A web application for the integration of multidimensional omics data within a network context Cancer Research
06/04/2012
Abstract 3975: Detecting patient mutomes by integrating DNA and RNA sequencing Cancer Research
06/04/2012
Abstract 3974: A comprehensive resequence-analysis of 250kb region of 8q24 in Africans Cancer Research
06/04/2012
Abstract 3973: Developing a public resource for structural biology and cancer pathway plasmids Cancer Research
06/04/2012
Abstract 3972: Tumor accessiblity and composition play a major role on the efficiency of efflux transporter inhibitor - cytotoxic drug combination: Analysis with a mathematical model Cancer Research
06/04/2012
Abstract 3971: DrGaP: A powerful tool for identifying driver genes and pathways in cancer sequencing studies Cancer Research
06/04/2012
Abstract 3969: A novel statistical method for detecting association of copy number variations in genome-wide association studies of cancers Cancer Research
06/04/2012
Abstract 3968: Exploring cancer datasets in the integrative genomics viewer (IGV) Cancer Research
06/04/2012
Abstract 3967: The Cancer Genome Project high throughput analysis pipeline Cancer Research
06/04/2012
Abstract 3966: GenomeSpace: An environment for frictionless bioinformatics Cancer Research
06/04/2012
Abstract 3965: An algorithm to detect somatic mutations in cancer specimens using mass spectrometric genotyping Cancer Research
06/04/2012
Abstract 3964: Inference of robust tumor phylogenetic markers from multi-sample data Cancer Research
06/04/2012
Abstract 3963: New software for imaging mass spectrometry data Cancer Research
06/04/2012
Abstract 3962: Mathematical models for cellular pharmacodynamics of fractionated radiation and radiochemotherapy Cancer Research
06/04/2012
Abstract 3961: Computational modeling of pancreatic cancer reveals growth and dissemination kinetics and suggests optimum treatment strategies Cancer Research
06/04/2012
Abstract 3960: Rapid and efficient large-scale somatic mutation validation approaches for cancer genome sequencing Cancer Research
06/04/2012
Abstract 3959: COSMIC: Mining the world's knowledge on somatic cancer mutations Cancer Research
06/04/2012
Abstract 3958: Multi-Reg: An integrative parallel approach to uncover drivers of cancer Cancer Research
06/04/2012
Abstract 3957: Cell death and growth arrest pathways mediating the actions of stilbene 5C in HCT-116 colon cancer cells Cancer Research
06/04/2012
Abstract 3956: BRCA1 chromatin dissociation induced by oncogene activation promotes formation of senescence-associated heterochromatin foci and senescence via chromatin remodeling factor BRG1 Cancer Research
06/04/2012
Abstract 3955: Overexpression of the 58-kDa microspherule protein (MSP58) triggers cellular senescence via the p53-p21 signaling axis Cancer Research
06/04/2012
Abstract 3954: mTOR inhibitor increases radiation sensitivity in a radiation-resistance cancer cells through induction of cellular senescence Cancer Research
06/04/2012
Abstract 3953: Senescence induced of smooth muscel protein 22-alpha (SM22) and Radiation patients change human-link genes expression level Cancer Research
06/04/2012
Abstract 3952: New advances in regulation of senescence by PML and the PML nuclear bodies Cancer Research
06/04/2012
Abstract 3951: Expression of SIRT1 and p27 during progression of human cervical cancer Cancer Research
06/04/2012
Abstract 3950: Differential functions of neuropeptide Y in Ewing's sarcoma - hypoxia as a switch Cancer Research
06/04/2012
Abstract 3949: In vivo imaging of tumor hypoxia by a new near-infrared fluorescent carbonic anhydrase IX-targeted agent Cancer Research
06/04/2012
Abstract 3948: Proteome analysis of ovarian cancer cell lines under hypoxic conditon by two-dimensional difference gel electrophoresis (2D-DIGE) Cancer Research
06/04/2012
Abstract 3947: Hypoxic regulation of RIO kinase 3 promotes cell migration and invasion Cancer Research
06/04/2012
Abstract 3946: Genome-wide characterization of hypoxic breast cancer transcriptome Cancer Research
06/04/2012
Abstract 3945: HIFs regulate alternative splicing of HIF target genes Cancer Research
06/04/2012
Abstract 3944: In-vitro evaluation of the Hypoxia Inducible Factor (HIF) pathway in head and neck squamous cell carcinoma (HNSCC) Cancer Research
06/04/2012
Abstract 3943: Invasion and degradation of extracellular matrix decreases in HIF-1{alpha} and HIF-2{alpha}-silenced MDA-MB-231 human breast cancer cells Cancer Research
06/04/2012
Abstract 3942: The role of vHL and REDD1 in predicting sensitivity to targeted therapies in renal cell carcinoma Cancer Research
06/04/2012
Abstract 3941: HAF promotes the switch from HIF-1{alpha} to HIF-2{alpha} signaling during chronic hypoxia and promotes stem cell characteristics Cancer Research
06/04/2012
Abstract 3940: Activation of Signal Transducer and Activator of Transcription 3 (STAT3) in ovarian cancer: The hypoxic implications Cancer Research
06/04/2012
Abstract 3939: Hypoxia-induced BRCA1 phosphorylation and degradation Cancer Research
06/04/2012
Abstract 3938: BNip3 limits HIF-1{alpha} stabilization and metastasis in a mouse model of breast cancer through effects on mitochondrial integrity and ROS generation Cancer Research
06/04/2012
Abstract 3937: SN-38 attenuates the chemoresistance acquired by colon cancer cells under hypoxic condition, via inhibition of hypoxia inducible factor (HIF) 1 Cancer Research
06/04/2012
Abstract 3936: A hemoglobin-based oxygen carrier enhances chemotherapy in a rat orthotopic HCC model Cancer Research
06/04/2012
Abstract 3935: Microfluidic analysis of triple negative breast cancer epithelial cells in response to chemotherapeutic treatments coupled with oxygen gradients Cancer Research
06/04/2012
Abstract 3934: HCV core protein upregulates the expression of vascular endothelial growth factor via the nuclear factor-{alpha}/hypoxia-inducible factor-1{alpha} axis under hypoxic conditions Cancer Research
06/04/2012
Abstract 3933: ER{alpha} phosphorylation patterns at hinge domain Ser294 and Ser305 differentiate ligand-dependent from ligand-independent receptor activation Cancer Research
06/04/2012
Abstract 3932: IL13R{alpha}2 regulates cell invasion, and is a therapeutic target for adrenocortical carcinoma Cancer Research
06/04/2012
Abstract 3931: Progesterone and estrogen affect the expression and secretion of heparin binding epidermal growth factor like growth factor (HB-EGF) in RL95-2 cells, an endometrial cancer cell line Cancer Research
06/04/2012
Abstract 3930: Ligand-independent activity of the mutant LNCaP androgen receptor drives cell proliferation in hormone-independent LNCaP tumor cells Cancer Research
06/04/2012
Abstract 3929: Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells: A novel therapeutic modality Cancer Research
06/04/2012
Abstract 3928: Inhibition of the ubiquitin proteasome system differentially regulates glucocorticoid receptor-mediated transcriptional processes Cancer Research
06/04/2012
Abstract 3927: Loss of bHLH transcription factor Id4 modulates androgen receptor activity in prostate cancer progression Cancer Research
06/04/2012
Abstract 3926: Abrogating tamoxifen resistance with the ribonucleoside analog, 8-amino adenosine Cancer Research
06/04/2012
Abstract 3925: IGF2 activation of HER2 receptor in HER2 positive breast cancer cell lines Cancer Research
06/04/2012
Abstract 3924: Alteration of the shape of the ligand estrogen receptor complex controls estrogen induced apoptosis in breast cancer Cancer Research
06/04/2012
Abstract 3923: Growth hormone activates ERK via EGFR, not IGF-IR, to potentiate estrogen-dependent breast cancer cell proliferation Cancer Research
06/04/2012
Abstract 3922: 20(S)-protopanaxadiol-aglycone inhibition of the development and growth of castration-resistant prostate cancer Cancer Research
06/04/2012
Abstract 3921: Androgens stimulate phosphorylation of ERK and AKT in thyroid cancer cells Cancer Research
06/04/2012
Abstract 3920: Off-target effects of the putative G-protein coupled estrogen receptor 1 (GPER) agonist G1 in ovarian and breast cancer cells Cancer Research
06/04/2012
Abstract 3919: Novel model to study NFkB driven resistance to endocrine treatment in breast cancer Cancer Research
06/04/2012
Abstract 3918: A structural role of androgen receptor in progression of prostate cancer cells from G1 to S phase Cancer Research
06/04/2012
Abstract 3917: Regulatory role of ROBO-1, a novel tumor suppressor on Androgen receptor and Wnt signaling during castration-resistant prostate cancer development: A novel molecular target for gene therapy Cancer Research
06/04/2012
Abstract 3915: Insulin-like growth factor 1 promotes cancer cell growth via RAC1 activation in ovarian epithelial cancer cells Cancer Research
06/04/2012
Abstract 3914: Androgen receptor (AR) degradation is controlled by the co-operation of PMEPA1 and the E3 ubiquitin ligase NEDD4-1 Cancer Research
06/04/2012
Abstract 3913: Estrogen receptor beta and estrogen receptor beta 5 in triple negative breast cancer cells: IGF-II role in regulation of estrogen receptor beta 5 Cancer Research
06/04/2012
Abstract 3912: The discovery of AZD4547: An orally bioavailable, potent and selective N-(5-Pyrazolyl)benzamide FGFR1-3 inhibitor Cancer Research
06/04/2012
Abstract 3911: Infrared vibrational frequency as a novel molecular descriptor for lead optimization of PKB/Akt inhibitors Cancer Research
06/04/2012
Abstract 3910: Lead optimization of a series of 5-aminopyrazol-imidazopyridine compounds as potent anaplastic lymphoma kinase inhibitors active against clinically relevant ALK mutations Cancer Research
06/04/2012
Abstract 3908: Norton-Simon modeling for the optimization of dose and schedule of palifosfamide in breast cancer Cancer Research
06/04/2012
Abstract 3907: Discovery and characterization of AZ285 as a potent and selective inhibitor of CK2 kinase Cancer Research
06/04/2012
Abstract 3906: Design, synthesis and biological evaluation of 2nd generation ezrin inhibitors for metastatic osteosarcoma Cancer Research
06/04/2012
Abstract 3905: Synthesis and structure activity relationship of substituted N,6-diphenyl-5,6-dihydrobenzo[h]quinazolin-2-amine as inhibitors of fibroblast growth factor receptors (FGFR) Cancer Research
06/04/2012
Abstract 3904: Pyridylthiazole-based ureas as inhibitors of Rho-associated protein kinases Cancer Research
06/04/2012
Abstract 3903: Synthesis of substituted N-{4-[(2-hydroxyethyl)sulfanyl]-3,6-dihydropyridin-1(2h)-yl} benzamide/benzenesulfonamide as antiinflamatory and anticancer agents Cancer Research
06/04/2012
Abstract 3902: Development of Aurora A inhibitors with ortho-halophenyl substituted pyrimidines: Unusual potency, SAR and X-ray crystallography studies. Cancer Research
06/04/2012
Abstract 3901: Estrogen receptor conformation sensing small molecules as novel anti-cancer agents Cancer Research
06/04/2012
Abstract 3899: NOSH compounds: Nitric oxide- and hydrogen sulfide-releasing hybrids, a new class of anti-inflammatory pharmaceuticals Cancer Research
06/04/2012
Abstract 3898: NOSH-aspirin: A novel nitric oxide- and hydrogen sulfide-releasing hybrid for treatment of colon cancer Cancer Research
06/04/2012
Abstract 3896: New heat shock protein 90 inhibitors based on the 1,2,3-triazole structure Cancer Research
06/04/2012
Abstract 3895: Rational design of small molecule inhibitors that bind to an allosteric pocket on human heat shock protein 70 (Hsp70) Cancer Research
06/04/2012
Abstract 3894: Discovery, synthesis and SAR studies of a novel nonpeptidic reversible proteosome inhibitor with low nano-molar chymotrypsin like activity Cancer Research
06/04/2012
Abstract 3893: Inhalational temozolomide-a new mode of treating malignant gliomas Cancer Research
06/04/2012
Abstract 3892: Anti-cooperative allosteric inhibitors of thymidylate synthase as novel antineoplastic agents Cancer Research
06/04/2012
Abstract 3891: NOSH-aspirin, a novel nitric oxide- and hydrogen sulfide-releasing hybrid, is a potent inhibitor of colon cancer cell growth Cancer Research
06/04/2012
Abstract 3890: The PhScN peptide as a highly potent inhibitor of basement membrane invasion in vitro and lung colonization in nude mice by metastatic human prostate cancer cells Cancer Research
06/04/2012
Abstract 3889: Substituted pyrrolo[2,3-d]pyrimidines as water soluble microtubule targeting agents Cancer Research
06/04/2012
Abstract 3888: Next generation cell engineering: the Jump-In cell engineering platform Cancer Research
06/04/2012
Abstract 3887: A screen for new cancer specific drugs that target centrosome clustering Cancer Research
06/04/2012
Abstract 3886: Development of a new DNA aptamer against primary cultured tumor endothelial cells by a cell-based SELEX method to discover a new drug delivery system Cancer Research
06/04/2012
Abstract 3885: A bi-functional fluorescent assay for the assessment of cytotoxicity and proliferation Cancer Research
06/04/2012
Abstract 3884: A novel, in vitro tankyrase 1 trans-ribosylation assay Cancer Research
06/04/2012
Abstract 3883: Miniaturizing the GloSensor&trade; cAMP assay for MC4R screening using the Echo(R) acoustic liquid handler Cancer Research
06/04/2012
Abstract 3881: BacMam-enabled biochemical and cellular assays to assess inhibitors of full-length receptor tyrosine kinases Cancer Research
06/04/2012
Abstract 3880: Application of tyramide signal amplification technology to high content analysis of cellular kinase translocation assays Cancer Research
06/04/2012
Abstract 3879: High-throughput, homogeneous in cyto assays to monitor histone H3 post-translational modifications Cancer Research
06/04/2012
Abstract 3878: A highly sensitive assay for the discovery of inhibitors of the histone methyltransferase DOT1L to treat MLL-rearranged leukemia Cancer Research
06/04/2012
Abstract 3877: ABT-737 synergizes with bortezomib to induce apoptosis: Activation of Bid, Bak, and Bax in the apoptotic response in malignant human glioma cells Cancer Research
06/04/2012
Abstract 3876: Role of Stat3 transcriptional activation in a preclinical mouse model of prostate cancer and potential as a therapeutic target Cancer Research
06/04/2012
Abstract 3875: Exploiting the Anticalin therapeutic protein platform for the treatment of cMet ligand-independent and dependent tumors - discovery and characterization of a highly specific and potent c-Met antagonist with drug-like properties Cancer Research
06/04/2012
Abstract 3874: A novel human fusion protein composed of the serine protease Granzyme B and VEGF121 to target the vasculature of solid tumors Cancer Research
06/04/2012
Abstract 3872: Targeting EGFR/HER2 signaling pathway by a dual receptor tyrosine kinase inhibitor BIBW2992 for radiosensitization in murine urothelial carcinoma Cancer Research
06/04/2012
Abstract 3871: Insulin-like growth factor 1 receptor (IGF1R) inhibitor BMS754807 is active against FLT3-ITD mutated acute myelogenous leukemia and activity is p53 dependent Cancer Research
06/04/2012
Abstract 3870: Construction and characterization of completely human serine protease therapeutics targeting Her2/neu Cancer Research
06/04/2012
Abstract 3869: Proteomics highlights which G-protein coupled receptors are candidates for ADC development Cancer Research
06/04/2012
Abstract 3868: ROR1 is expressed in human breast cancer and associated with enhanced tumor-cell growth Cancer Research
06/04/2012
Abstract 3867: Dual blockade of HER2 in HER2-overexpressing tumor cells does not eliminate HER3 function completely: Clinical implications Cancer Research
06/04/2012
Abstract 3866: TWEAK receptor (Fn14) Is a novel target in melanoma: Characterization of unique targeted therapeutics Cancer Research
06/04/2012
Abstract 3865: The rGel/BLyS fusion toxin enhances the therapeutic effects of bortezomib in in vitro and in vivo models of mantle cell lymphoma. Cancer Research
06/04/2012
Abstract 3864: Biological basis of pan-ErbB receptor targeting for malignant melanoma treatment Cancer Research
06/04/2012
Abstract 3863: Aneuploid human colonic epithelial cells are sensitive to AICAR-induced growth inhibition through EGFR degradation Cancer Research
06/04/2012
Abstract 3862: The potential role of CD44 in liver regeneration Cancer Research
06/04/2012
Abstract 3861: Fusion toxin BLyS-gelonin inhibits growth of B-NHL cell lines in vitro and in vivo Cancer Research
06/04/2012
Abstract 3860: Glycosylation is indispensable for ephrin A1 activity Cancer Research
06/04/2012
Abstract 3859: Multivalency of non-peptide integrin {alpha}V{beta}3 antagonist slows tumor growth Cancer Research
06/04/2012
Abstract 3858: Gains in FGF19 are predictive of response to the fibroblast growth factor receptor (FGFR) small molecule tyrosine kinase inhibitor BGJ 398 in vitro Cancer Research
06/04/2012
Abstract 3857: Smac mimetic TL32711 and TRAIL synergistically induce apoptosis of germinal center B lymphoma cells Cancer Research
06/04/2012
Abstract 3856: Dimerized single chain TRAIL-receptor agonists do not depend on Fc-gamma-receptor cross-linking for anti-tumor efficacy in vivo Cancer Research
06/04/2012
Abstract 3855: Inhibitors of apoptosis (IAPs) in gastrointestinal stromal tumors Cancer Research
06/04/2012
Abstract 3854: Gamma-linolenic Acid (GLA) sensitizes pancreatic cancer cells to gemcitabine Cancer Research
06/04/2012
Abstract 3853: TAS266, a novel tetrameric nanobody agonist targeting death receptor 5 (DR5), elicits superior antitumor efficacy than conventional DR5-targeted approaches Cancer Research
06/04/2012
Abstract 3852: Improved coiled-coil design enhances interaction with Bcr-Abl and induces apoptosis Cancer Research
06/04/2012
Abstract 3851: Killing of Kras mutant colon cancer cells by the {alpha}GBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivo Cancer Research
06/04/2012
Abstract 3850: Production of recombinant lunasin peptides with enhanced anticancer activity using transient expression in tobacco Cancer Research
06/04/2012
Abstract 3849: Triptolide reduces activity of RNA polymerase II Cancer Research
06/04/2012
Abstract 3848: Preclinical profile of AZD3514: A small molecule-targeting androgen receptor function with a novel mechanism of action and the potential to treat castration-resistant prostate cancer Cancer Research
06/04/2012
Abstract 3847: Lupeol, a novel inhibitor of Wnt/{beta}-catenin signaling: Implications in colon cancer therapy Cancer Research
06/04/2012
Abstract 3846: Vitamin D3 potentiates the antitumor effects of arsenic trioxide in human leukemia (HL-60) cells Cancer Research
06/04/2012
Abstract 3845: Antitumor activity of SEL120: An orally available dual inhibitors of Haspin/CDK9, for standalone and combination therapy with AuroraB inhibitors in solid tumors and hematopoietic malignancies Cancer Research
06/04/2012
Abstract 3844: A novel sorafenib-derivative SC-1 induces apoptosis in breast cancer cells through STAT3 inhibition Cancer Research
06/04/2012
Abstract 4023: Genome-wide analysis of CpG island methylation identified OTX1, OSR1 and ONECUT2 as biomarkers for recurrent bladder cancer detection in voided urine Cancer Research
06/04/2012
Abstract 4022: HPV16 CpG methylation patterns determined by next-gen bisulfite sequencing and association with cervix precancer/cancer Cancer Research
06/04/2012
Abstract 4021: Breaking the dogma: AWT1 hypermethylation in myeloid leukemia despite high expression Cancer Research
06/04/2012
Abstract 4020: The Sox17 gene hypermethylation is useful as a molecular diagnostic application in early stage of gastric cancer Cancer Research
06/04/2012
Abstract 4019: Galanin has a tumor suppressor activity and is frequently inactivated by aberrant promoter methylation in head and neck cancer Cancer Research
06/04/2012
Abstract 4018: DNA methylation controls CHST11 gene expression in breast cancer Cancer Research
06/04/2012
Abstract 4017: Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers Cancer Research
06/04/2012
Abstract 4016: Epigenetic regulation of CXCR3 splicing in prostate cancer cells Cancer Research
06/04/2012
Abstract 4015: TTLL12: A promising therapeutic target for prostate cancer Cancer Research
06/04/2012
Abstract 4014: The gp130/Stat3 pathway enables Wnt induced regeneration and tumorigenesis in the mouse intestine Cancer Research
06/04/2012
Abstract 4013: The positive role of TP{gamma} in the induction of COX-2, TxA2 and cell growth by NNK in human lung cancer cells Cancer Research
06/04/2012
Abstract 4012: Pyruvate kinase M2 promotes the growth and migration of gastric cancer cell via nuclear factor-kappa B and its target genes Cancer Research
06/04/2012
Abstract 4011: Why does this APC exon 9 mutation causes severe and not attenuated familial adenomatous polyposis (FAP) Cancer Research
06/04/2012
Abstract 4010: New AXIN2 germline variant in a Spanish family with an attenuated form of FAP without oligondontia or ectodermal dysplasia signs Cancer Research
06/04/2012
Abstract 4009: Hypoxia potentiates Runx2-mediated increased Bcl-2 expression in prostate cancer resulting in apoptosis resistance Cancer Research
06/04/2012
Abstract 4008: Nuclear localization of Lymphocyte-specific protein tyrosine kinase (Lck) and its role in regulating LIM domain only 2 (LMO2) gene Cancer Research
06/04/2012
Abstract 4007: Different expression of AHCYL1 affecting ovarian carcinogenesis between chickens and women Cancer Research
06/04/2012
Abstract 4005: Active SHP2 mutant induces lung hyperproliferative lesions and adenoma in transgenic mice Cancer Research
06/04/2012
Abstract 4004: P21-activated kinases (PAKs) are novel therapeutic targets in human breast cancer Cancer Research
06/04/2012
Abstract 4003: Involving of PGD2 signal pathway in the RIG1-mediated suppression of cell invasion in testis cells Cancer Research
06/04/2012
Abstract 4002: Functional investigation and identification of dephosphorylation targets of tumor-suppressive protein tyrosine phosphatase, PTPRG Cancer Research
06/04/2012
Abstract 4001: SOX7 is a potential tumor suppressor in breast cancer Cancer Research
06/04/2012
Abstract 4000: Restoring LSAMP expression decreases the proliferation rate in osteosarcomas Cancer Research
06/04/2012
Abstract 3999: Experimental study of tumor suppressor gene RBM5 in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 3998: The role of serum amyloid A1 (SAA1) in nasopharyngeal carcinoma (NPC) Cancer Research
06/04/2012
Abstract 3997: TUSC3 (N33) affects protein N-glycosylation and proliferation of prostate cancer cells Cancer Research
06/04/2012
Abstract 3996: Identification of DEC1-interacting protein DNAJB6 and its role in esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 3994: Loss of STAT2 enhances the establishment of B16 melanoma tumors Cancer Research
06/04/2012
Abstract 3992: Tid1, a tumor suppressor, regulating the cancer initiation properties of HNSCC Cancer Research
06/04/2012
Abstract 3991: Protein phosphatase 2A (PP2A) downregulation is associated with androgen-independent and aggressive phenotypes in prostate cancer Cancer Research
06/04/2012
Abstract 3990: SPANXA1 suppresses tumor metastasis through WNT pathway in lung cancer Cancer Research
06/04/2012
Abstract 3696: Psychological stress inhibits, while GABA potentiates, the prevention of pancreatic cancer progression in xenografts by celecoxib Cancer Research
06/04/2012
Abstract 3695: Efficacy of gemcitabine combined with hyperthermia therapy in the treatment of unresectable pancreatic cancer: Phase II study Cancer Research
06/04/2012
Abstract 3693: Power of FOLFOXIRI+B-mab as preoperative chemotherapy for multiple liver metastases of colorectal cancer -Relationship between clinical response and pathological response- Cancer Research
06/04/2012
Abstract 3692: Single center phase II study of yttrium-90 radioactive resin microspheres in the treatment of liver predominant metastatic colorectal adenocarcinoma after failure of 1st-line combination chemotherapy Cancer Research
06/04/2012
Abstract 3691: The correlation analysis of postoperative anxiety scale of colorectal cancer patient and the postoperative complication Cancer Research
06/04/2012
Abstract 3690: 19-nor-1{alpha}-25-dihydroxyvitamin D2 induces gastric cancer cell apoptosis and cell cycle arrest and inhibits STAT3 mediated inflammation Cancer Research
06/04/2012
Abstract 3689: Association of thymidylate synthase gene polymorphisms with efficacy and toxicity of oral fluoropyrimidine based chemotherapy in advanced gastric cancer Cancer Research
06/04/2012
Abstract 3688: Akt pathway genes classify GBM into 6 prognostic subgroups with different clinical and molecular features Cancer Research
06/04/2012
Abstract 3687: An integrative genomics approach identifies distinct molecular and epigenetic subgroups of pediatric glioblastoma Cancer Research
06/04/2012
Abstract 3686: Single cell assays of heterogeneity and clonality in leukemia Cancer Research
06/04/2012
Abstract 3685: Analysis of EZH2 and TTF-1 protein expression identifies a subset of lung adenocarcinomas with better prognosis Cancer Research
06/04/2012
Abstract 3684: Targeting Aurora kinase in peripheral T-cell non-Hodgkin's lymphomas Cancer Research
06/04/2012
Abstract 3683: Crenolanib, a novel Type I, mutant-specific inhibitor of Class III receptor tyrosine kinases, preferentially binds to phosphorylated kinases Cancer Research
06/04/2012
Abstract 3682: Overexpression and cell proliferation-regulating function of CRKL protein in gastric cancer Cancer Research
06/04/2012
Abstract 3681: Multi-scale analysis of everolimus and sorafenib combination in pancreatic cancer xenografts Cancer Research
06/04/2012
Abstract 3680: Drug screening for glioblastoma patients Cancer Research
06/04/2012
Abstract 3679: Paired tumor and normal whole genome and transcriptome sequencing of transitional cell carcinoma of the upper urinary tract Cancer Research
06/04/2012
Abstract 3678: Combination analysis of oncogenic mutations and signaling pathway proteins identifies effective therapeutic targets in colorectal cancers Cancer Research
06/04/2012
Abstract 3677: Pattern and distribution of BRAF/NRAS and P16CDKN2A mutations among primary an secondary lesions in melanoma patients Cancer Research
06/04/2012
Abstract 3676: The hypoxia-activated pro-drug tirapazamine suppresses outgrowth of colorectal liver metastases following radiofrequency ablation Cancer Research
06/04/2012
Abstract 3674: Next generation cancer gene sequencing for clinically actionable mutations Cancer Research
06/04/2012
Abstract 3673: Molecular analysis of pheochromocytoma after maternal transmission of SDHD mutation elucidates mechanism of parent-of-origin effect. Cancer Research
06/04/2012
Abstract 3671: A distinct subset of atypical Spitz tumors is characterized by BRAF mutation and loss of BAP1 expression Cancer Research
06/04/2012
Abstract 3669: Autocrine interleukin/STAT3 signaling in breast implant-associated T cell anaplastic large cell lymphoma cell lines suggests a mechanism for tumor progression and effective therapy Cancer Research
06/04/2012
Abstract 3668: Inhibition of HSP90 with NVP-AUY922 induces a synergistic effect in HER2-amplified, trastuzumab-resistant breast and gastric cancer Cancer Research
06/04/2012
Abstract 3667: Inactivating BRAF mutations confer dasatinib sensitivity in lung cancer Cancer Research
06/04/2012
Abstract 3665: An EMT gene expression diagnostic predicts resistance to EGFR and MEK-targeted therapies in cell lines and patients Cancer Research
06/04/2012
Abstract 3664: Breast cancer companion diagnostic platform based on objectively defined tumor co-expression patterns stratifies multiple clinical and therapeutic endpoints comparison to existing molecular subtyping definitions Cancer Research
06/04/2012
Abstract 3663: A gene signature for predicting outcome in patients with basal-like breast cancer Cancer Research
06/04/2012
Abstract 3662: FGFR2 gene amplification and overexpression frequently occur in squamous cell carcinomas of the lung Cancer Research
06/04/2012
Abstract 3661: Notch2 and Six1 are upregulated during progression of early-stage lung adenocarcinoma and define its unfavorable subset at advanced stages Cancer Research
06/04/2012
Abstract 3660: Crenolanib: A next generation FLT3 inhibitor Cancer Research
06/04/2012
Abstract 3659: The AKT inhibitor MK-2206 promotes apoptosis in acute myeloid leukemia cells Cancer Research
06/04/2012
Abstract 3658: The association of mitochondrial DNA content with bladder cancer risk and outcome Cancer Research
06/04/2012
Abstract 3657: MCM7, ADAM10, TRIM29, Aurora Kinase B, and Cyclin D1: A panel of prognostic protein markers for progression in non-muscle invasive bladder cancer - a multicenter tissue microarray validation study Cancer Research
06/04/2012
Abstract 3656: Cathepsin E, Maspin, PLK1, and Survivin are promising prognostic protein markers for progression in non-muscle invasive bladder cancer Cancer Research
06/04/2012
Abstract 3655: Stem cell-associated gene Lin-28B genotype and phenotype in epithelial ovarian cancer and their associations with disease survival outcomes Cancer Research
06/04/2012
Abstract 3654: Prognostic role of androgen receptor in bladder cancer Cancer Research
06/04/2012
Abstract 3653: Cancerous inhibitor of PP2A (CIP2A) expression for bladder cancer diagnostics Cancer Research
06/04/2012
Abstract 3652: Pegylated arginine deiminase (ADI-PEG20) as a potential therapeutic agent for rarer variants of bladder cancer that are deficient for argininosuccinate synthetase Cancer Research
06/04/2012
Abstract 3651: Foxp3 expression correlates with survival in urothelial carcinoma of the bladder Cancer Research
06/04/2012
Abstract 3650: Serous ovarian carcinoma patients with high alpha-folate receptor had poorer outcome by reducing cytotoxic chemo-response through anti-apoptotic pathway Cancer Research
06/04/2012
Abstract 3649: Expression of CXCR5 and its natural ligand CXCL13 in ovarian cancer Cancer Research
06/04/2012
Abstract 3648: Nanofluidic technologies to define biological and response profile in neoadjuvant patients with ovarian cancer Cancer Research
06/04/2012
Abstract 3647: Integrin {beta}5 as a new target in ovarian cancer treatment Cancer Research
06/04/2012
Abstract 3646: Expression of death receptor 6 (DR6) increases in association with ovarian tumor development and progression Cancer Research
06/04/2012
Abstract 3645: Integrative molecular profiling in serous epithelial ovarian cancer for identification of biomarkers of chemoresistance Cancer Research
06/04/2012
Abstract 3644: The PSP94{alpha}prostasin pathway and early detection of ovarian cancer Cancer Research
06/04/2012
Abstract 3642: Phospho-CHK1 as a prognostic biomarker in ovarian cancer and a potential target in platinum-resistant disease Cancer Research
06/04/2012
Abstract 3641: The predictive and prognostic roles of DNA damage response genes in epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 3640: Overexpression of five novel biomarkers in human prostate tissues and cell lines Cancer Research
06/04/2012
Abstract 3639: Systemic inflammation and survival of patients with prostate cancer: Evidence from the Glasgow Inflammation Outcome Study. Cancer Research
06/04/2012
Abstract 3638: Detecting prostate cancer in BRCA1 and BRCA2 mutation carriers: A role for EN2 Cancer Research
06/04/2012
Abstract 3637: Loss of prostate derived Ets (E-twenty six) transcription factor (PDEF) predicts patients at the highest risk of metastatic prostate cancer Cancer Research
06/04/2012
Abstract 3636: Prognostic biomarker potential of ANPEP (CD13) in prostate cancer revealed by large-scale tissue microarray and DNA methylation analyses Cancer Research
06/04/2012
Abstract 3635: Association of reduction in serum androgens and change in serum PSA in patients treated with abiraterone acetate (AA): A subset analysis of the COU-AA-301 phase 3 randomized trial Cancer Research
06/04/2012
Abstract 3634: Molecular determinants of taxane activity using CTCs from CRPC patients Cancer Research
06/04/2012
Abstract 3633: Prognostic value of chromogranin A and alkaline phosphatase in patients with advanced neuroendocrine tumor Cancer Research
06/04/2012
Abstract 3632: Epigenetic silencing and biomarker potential of miR-224, miR-452 and their host gene GABRE in prostate cancer Cancer Research
06/04/2012
Abstract 3631: Secretory phospholipase A2-IIa is a target gene of the HER/HER2-elicited pathway and a potential plasma biomarker for poor prognosis of prostate cancer Cancer Research
06/04/2012
Abstract 3630: Non-enrichment based method for analysis of androgen receptor expression in circulating tumor cells (CTCs) in patients with metastatic castrate resistant prostate cancer Cancer Research
06/04/2012
Abstract 3629: HOXA10 expression profiles in prostate cancer Cancer Research
06/04/2012
Abstract 3628: Predict prostate cancer aggressiveness quantitatively using a nanoparticle test Cancer Research
06/04/2012
Abstract 3627: Head and neck squamous cell carcinoma in African Americans: A simple oral rinse detection test using solCD44 and total protein Cancer Research
06/04/2012
Abstract 3626: Quantitative analysis of microRNAs by in situ hybridization reveals prognostic value of miRNAs in melanoma and breast cancer Cancer Research
06/04/2012
Abstract 3625: A multiplexed marker-based algorithm for diagnosis of carcinoma of unknown primary (CUP) using circulating tumor cells Cancer Research
06/04/2012
Abstract 3624: Circulating sEGFR arises through a fibronectin/integrin-regulated proteolytic cleavage event: Analogy to HER2 shedding Cancer Research
06/04/2012
Abstract 3623: Clinical significance of serum tumor markers in patients with esophageal cancer Cancer Research
06/04/2012
Abstract 3622: Predicting response to EC145 therapy using the folate receptor-specific radiodiagnostic imaging agent, 99mTc-EC20 Cancer Research
06/04/2012
Abstract 3621: Polymorphisms in genes related to DNA repair and to apoptosis: Link with the outcome after radiochemotherapy in head and neck cancer patients Cancer Research
06/04/2012
Abstract 3620: A multiplex quantitative immunofluorescence assay for DNA damage repair in response to cytotoxic treatment Cancer Research
06/04/2012
Abstract 3619: The absence of cleaved caspase-3 in circulating tumor cells detected using a non-enrichment-based assay Cancer Research
06/04/2012
Abstract 3618: Rapid and quantitative lateral flow point-of-care Therapeutic Drug Monitoring (TDM) assays for LH and FSH Cancer Research
06/04/2012
Abstract 3617: A novel competition-based antibody array technology as a potential platform for cancer biomarker discovery Cancer Research
06/04/2012
Abstract 3616: Validation and fitness testing of a quantitative immunoassay for HIF1{alpha} in biopsy specimens Cancer Research
06/04/2012
Abstract 3615: A SNP538(G>A) in ABCC11/MRP8 determines sensitivity for antimetabolites Cancer Research
06/04/2012
Abstract 3614: Development of a contra-indicatory biomarker to predict drug resistance and treatment failure Cancer Research
06/04/2012
Abstract 3613: Methylated PLK2 predicts response to taxanes Cancer Research
06/04/2012
Abstract 3612: Detection and quantification of tumor-derived microparticles in a murine orthotopic tumor progression model Cancer Research
06/04/2012
Abstract 3611: Identifying gene expression markers of anticancer drug response using large scale genomic and drug response databases established from patient derived tumors Cancer Research
06/04/2012
Abstract 3610: GW182 associates with circulating microvesicles and microRNA in human plasma Cancer Research
06/04/2012
Abstract 3609: Generation and characterization of a novel monoclonal antibody recognizing both the blood and tissue form of human PCBP-1 Cancer Research
06/04/2012
Abstract 3608: Measurement of kinase activity in cancer cell lines and tumor tissue using a tyrosine kinase peptide substrate array Cancer Research
06/04/2012
Abstract 3607: Differential protein expression and miR content of sorted subsets of circulating microvesicles from cancer patients and healthy controls Cancer Research
06/04/2012
Abstract 3606: Dynamic expression of pepsinogen I in gastric diseases sequence and relationship with Helicobacter pylori infection Cancer Research
06/04/2012
Abstract 3605: Effects of antibody-mediated EGF-receptor inhibition on ERK 1/2 isoform phosphorylation in organoid cultures Cancer Research
06/04/2012
Abstract 3604: Elevated sigma-2 receptor/Pgrmc1 (progesterone receptor membrane component 1) levels as a potential cancer biomarker in tumors and plasma Cancer Research
06/04/2012
Abstract 3603: Identification of potential pharmacodynamic markers for HER3 targeted cancer treatment by a multi-technology approach Cancer Research
06/04/2012
Abstract 3602: Differential effects of mTOR and PI3K inhibition on the phosphorylation of polysome-associated proteins Cancer Research
06/04/2012
Abstract 3601: Telomere length assessment in human archival tumor tissues by quantitative PCR method (qTL) Cancer Research
06/04/2012
Abstract 3599: Expression and function of HFE in mammary gland iron homeostasis and its relevance to breast cancer Cancer Research
06/04/2012
Abstract 3598: The role of adiposity in racial and ethnic disparities in prostate cancer occurrence and progression: A systematic literature review Cancer Research
06/04/2012
Abstract 3597: The Chicago Colorectal Cancer Consortium (CCCC) experience: Understanding colorectal cancer disparities Cancer Research
06/04/2012
Abstract 3596: Globally, minorities are at increased risk for lung cancer Cancer Research
06/04/2012
Abstract 3595: Hepatocellular carcinoma and diabetes among Latinos: Implications for prevention Cancer Research
06/04/2012
Abstract 3594: Impact of metformin on HCC prognosis Cancer Research
06/04/2012
Abstract 3593: Tumor size and lymph node metastases in African-American and European-American women with breast cancer Cancer Research
06/04/2012
Abstract 3592: Risk factors of prostate cancer in African American men Cancer Research
06/04/2012
Abstract 3591: Triple negative (c-KIT, BRAF, NRAS) acral lentiginous melanoma in Hawaii: Molecular profiling in a multi-ethnic population Cancer Research
06/04/2012
Abstract 3590: Use of four biomarkers to evaluate survival disparity between black women and white women 35 to 64 years of age at diagnosis with invasive breast cancer Cancer Research
06/04/2012
Abstract 5326: ID3 contributes to cerebrospinal fluid seeding and poor prognosis of medulloblastoma Cancer Research
06/04/2012
Abstract 5325: Role of MUC13 in colon cancer progression Cancer Research
06/04/2012
Abstract 5324: H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM Cancer Research
06/04/2012
Abstract 5323: Fractalkine receptor CX3CR1 regulates peritoneal dissemination of ovarian carcinoma Cancer Research
06/04/2012
Abstract 5322: SOD2 enhances cell migration and invasion of tongue squamous cell carcinoma via H2O2-dependent Snail signaling Cancer Research
06/04/2012
Abstract 5321: Tyrosine kinase activation by the metastasis promoting protein S100A4 Cancer Research
06/04/2012
Abstract 5320: Sonic hedgehog in non-small cell lung cancer lymph node metastasis; ROS and PI3kinase/Akt signaling pathway Cancer Research
06/04/2012
Abstract 5319: BRCA1-IRIS overexpression promotes formation of aggressive breast cancers Cancer Research
06/04/2012
Abstract 5318: DPC4 loss results in the activation of alternative oncogenic pathways in pancreatic cancer Cancer Research
06/04/2012
Abstract 5317: Role of TGF-beta superfamily ligand and mechanism of osteoblastic tumorigenesis of prostate cancer cells Cancer Research
06/04/2012
Abstract 5316: GSK3{beta}-dependent phosphorylation of LCRMP-1 is required for filopoda formation and tumor invasion Cancer Research
06/04/2012
Abstract 5315: WAVE3 modulates the invasion-metastasis cascade by regulating invadopodia structures, MMP activity and ECM degradation Cancer Research
06/04/2012
Abstract 5314: An oncogenic splice variant of the KLF6 tumor suppressor gene is associated with poor survival and is a potent driver of breast cancer metastasis Cancer Research
06/04/2012
Abstract 5313: Sustained hypercalcemia primes non-invasive breast cancer cells for metastasis to high calcium microenvironments Cancer Research
06/04/2012
Abstract 5312: Identification of novel HIF-1-dependent target genes in a murine model of breast cancer Cancer Research
06/04/2012
Abstract 5311: Transducer of Cdc42-dependent actin assembly-1 (Toca-1) promotes breast cancer invasion and metastasis Cancer Research
06/04/2012
Abstract 5310: Regulation of metastatic breast cancer by E2F transcription factors Cancer Research
06/04/2012
Abstract 5309: Understanding the function of EZH2 as a determinant of breast cancer invasion and metastasis Cancer Research
06/04/2012
Abstract 5308: Id-1 gene and protein as novel therapeutic targets for metastatic cancer Cancer Research
06/04/2012
Abstract 5306: Overexpression of RAD51 promotes brain metastases from breast cancer Cancer Research
06/04/2012
Abstract 5305: Phosphorylations of Serine-10 and Tyrosine-198 residues in the cytoplasmic mislocalized p27 are critical to migration and invasion of osteosarcoma cells Cancer Research
06/04/2012
Abstract 5304: RNA sequencing of circulating tumor cells implicates WNT signaling in pancreatic cancer metastasis Cancer Research
06/04/2012
Abstract 5303: The role of the anti-hyperglycemic drug metformin in regulating tumor angiogenesis Cancer Research
06/04/2012
Abstract 5302: Characterization the role of leukocyte cell-derived chemotaxin 2 (LECT2) in angiogenesis Cancer Research
06/04/2012
Abstract 5301: Blood vessel structure and expression of permeability related factors in advanced lung cancer complicated with pleural effusion Cancer Research
06/04/2012
Abstract 5300: Endothelial colony forming cells (ECFCs) in multiple myeloma Cancer Research
06/04/2012
Abstract 5299: VEGF receptor-3 interacts with PI3K directly to regulate lymphangiogenesis Cancer Research
06/04/2012
Abstract 5298: Abnormal VEGF-induced Ca2+ signaling in purified tumor endothelial cells Cancer Research
06/04/2012
Abstract 5297: Autocrine stimulation of VEGFR-2 by leptin is associated with Notch signaling pathway and cancer stem cell marker expression Cancer Research
06/04/2012
Abstract 5296: The role of VEGF receptors 1 and 2 on tumor vascularization and progression in single VEGF isoform expressing tumors Cancer Research
06/04/2012
Abstract 5295: Detection of VEGFA gene amplification in different neoplastic entities using four different technologies Cancer Research
06/04/2012
Abstract 5294: Increased angiogenesis resulting from TIMP-1 inhibition of TSP-1 is mediated by PI3kinase and FAK interactions Cancer Research
06/04/2012
Abstract 5293: In vitro modeling of tumor-derived endothelial cell derivation Cancer Research
06/04/2012
Abstract 5292: Identification of antiangiogenic small molecule natural products targeting anthrax toxin receptor 2 Cancer Research
06/04/2012
Abstract 5290: Heme oxygenase 1 (HO-1): An auspicious target for state of the art anti-angiogenic therapeutic strategies and new insights in prostate carcinogenesis Cancer Research
06/04/2012
Abstract 5289: In human endothelial cell line Wnt-beta-catenin pathway controls transcription of lymphoid enhancer-binding factor 1, a representative of vertebrate-specific Lef1/Tcf1 sub-family enhancing matrix metalloproteinase-2 transcription and endothelial cell invasion Cancer Research
06/04/2012
Abstract 5288: Glioma stem cells stimulate the motility of brain endothelial cells: Identification of cell-adhesion molecules mediating motility and direct interaction Cancer Research
06/04/2012
Abstract 5287: RNA binding protein RBM3 promotes metastasis through induction of hemangiogenesis and lymphangiogenesis Cancer Research
06/04/2012
Abstract 5286: Enhancing role of tumor cell gangliosides in tumor angiogenesis Cancer Research
06/04/2012
Abstract 5285: ADAM12: A novel mediator of tumor angiogenesis Cancer Research
06/04/2012
Abstract 5284: EMMPRIN mediates VEGF activation of VEGFR-2 in melanoma cells Cancer Research
06/04/2012
Abstract 5283: Autophagy regulation of angiogenesis in human neuroblastoma Cancer Research
06/04/2012
Abstract 5282: Leptin induces Notch in endothelial cells: Role of VEGFR-2 transactivation Cancer Research
06/04/2012
Abstract 5281: Regulation of tumor growth and angiogenesis by Wilms tumor 1(WT1) Cancer Research
06/04/2012
Abstract 5280: Activation of sphingosine kinase 1 is necessary for angiopoietin 2-induced hemangiogenesis and lymphangiogenesis Cancer Research
06/04/2012
Abstract 5279: Over-expression of EGFRviii induces an angiogenic switch in infiltrative human glioblastomas Cancer Research
06/04/2012
Abstract 5277: MMP-2 suppression abrogates irradiation-induced microtubule formation in endothelial cells by inhibiting {alpha}v{beta}3-mediated SDF-1/CXCR4 signaling Cancer Research
06/04/2012
Abstract 5276: Roles of BMP-9 signals during the formation of tumor vessels Cancer Research
06/04/2012
Abstract 5275: Biglycan is a specific marker and an autocrine angiogenic factor of tumor endothelial cells Cancer Research
06/04/2012
Abstract 5274: MicroRNA-214 /hepatoma-derived growth factor paracrine pathway contributes to hypervascularity of human hepatoma Cancer Research
06/04/2012
Abstract 5273: XenTech patient-derived xenograft (PDX) panels: a clinically relevant platform for drug efficacy, target validation and predictive biomarker discovery studies Cancer Research
06/04/2012
Abstract 5272: A novel organotypic 3D invasion platform to advance anticancer drug development Cancer Research
06/04/2012
Abstract 5270: Evaluation of Cell-able spheroid culture system for culturing patient derived primary tumor cells Cancer Research
06/04/2012
Abstract 5269: Cell matrix interactions in a 3D alginate cell culture system Cancer Research
06/04/2012
Abstract 5268: Standardized and validated ATCC breast cancer panels: A tool for the rapid validation of biological hypotheses. Cancer Research
06/04/2012
Abstract 5267: Mouse models of cancer at The Jackson Laboratory Repository Cancer Research
06/04/2012
Abstract 5266: Anti-cancer drug development using bioactive compounds from Tillandsia recurvata in mouse models of human cancer Cancer Research
06/04/2012
Abstract 5264: Advantages of patient primary tumor models versus tumor cell lines established models for testing anticancer agents Cancer Research
06/04/2012
Abstract 5263: The APC tumor suppressor controls epithelial polarization and morphogenesis Cancer Research
06/04/2012
Abstract 5262: Disruption of alternative and classical NF-kappaB signaling patterns: Connections to branching morphogenesis and mammary tumorigenesis Cancer Research
06/04/2012
Abstract 5261: Irinophore C, a liposomal formulation of irinotecan, has anti-vascular effects in primary tumors of colorectal cancer grown orthotopically in mice Cancer Research
06/04/2012
Abstract 5260: Genomic gains in prostatic carcinoma and proliferative inflammatory atrophy in dogs Cancer Research
06/04/2012
Abstract 5259: Non-invasive determination of in vivo myeloperoxidase activity in ovarian cancer mouse model Cancer Research
06/04/2012
Abstract 5258: Characterization of canine lower urinary tract carcinoma cell lines with variable DNA mismatch repair proficiency derived from a single tumor Cancer Research
06/04/2012
Abstract 5257: Manipulating the Noxa/Bim axis undermines the multicellular resistance of 3D tumor spheroids Cancer Research
06/04/2012
Abstract 5256: Gender bias in rat models of colorectal cancer is owing to male hormone promotion, not female hormone protection Cancer Research
06/04/2012
Abstract 5255: Methionine restriction limits prostate tumor cell proliferation Cancer Research
06/04/2012
Abstract 5254: Xenograft-derived 3D cultures of hematological maligancies ex vivo and in vivo as a model system to investigate efficacy of antitumor compounds Cancer Research
06/04/2012
Abstract 5253: MEK-ERK pathway inhibition reduces mucin production in a murine xenograft model of pseudomyxoma peritonei Cancer Research
06/04/2012
Abstract 5252: Utilization of TumorGraft technology for personalized breast cancer treatment Cancer Research
06/04/2012
Abstract 5251: Branching morphogenesis in the mammary gland is regulated by sprouty-2 Cancer Research
06/04/2012
Abstract 5250: Optimization of an orthotopic mouse model for in vivo fluorescent uPA imaging in breast cancer Cancer Research
06/04/2012
Abstract 5249: LuCaP prostate cancer xenografts: Models that allow clinically relevant investigation of prostate cancer in a preclinical setting Cancer Research
06/04/2012
Abstract 5248: A novel ovarian cancer imaging agent based on integrin ligation Cancer Research
06/04/2012
Abstract 5247: Use of two markers of hypoxia to study migration, re-oxygenation and repopulation of originally hypoxic cells in MCF-7 tumor xenografts following chemotherapy Cancer Research
06/04/2012
Abstract 5246: Use of {gamma}H2aX and other biomarkers to quantify distribution of drug activity in solid tumors Cancer Research
06/04/2012
Abstract 5244: The Heme binding protein HRG-1 controls pH and enhances the invasive potential of cancer cells Cancer Research
06/04/2012
Abstract 5243: Reductions in hypoxia in the tumor microenvironment after Listeria monocytogenes-LLO based immunotherapy Cancer Research
06/04/2012
Abstract 5242: Pancreatic cancer cell type specific oxygen dependent growth and drug sensitivity Cancer Research
06/04/2012
Abstract 5241: Development of a single Listeria monocytogene-based vaccine simultaneously targeting two antigens Cancer Research
06/04/2012
Abstract 5240: Breast cancer in the metastatic niche: A role for stress-induced dormancy Cancer Research
06/04/2012
Abstract 3709: Synergistic effects of obatoclax (GX15-070) and bortezomib (BTZ) in non-Hodgkin's lymphoma Cancer Research
06/04/2012
Abstract 3708: Phase II study of panitumumab plus irinotecan as second-line therapy for advanced esophageal adenocarcinoma Cancer Research
06/04/2012
Abstract 3707: Captopril inhibits colorectal cancer liver metastases following 70% partial hepatectomy in a mouse model Cancer Research
06/04/2012
Abstract 3706: Feasibility of Methacetin C13 breath test in assessing liver function in patient who had liver resection due to HCC Cancer Research
06/04/2012
Abstract 3705: Multicenter phase II clinical trial of gemcitabine and liposomal paclitaxel combination chemotherapy in patients with advanced biliary cancer Cancer Research
06/04/2012
Abstract 3704: Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension in a single-arm Phase II study Cancer Research
06/04/2012
Abstract 3703: Randomized trial of autologous dendritic cell vs tumor cell vaccines in patients with metastatic melanoma Cancer Research
06/04/2012
Abstract 3701: Phase II study of BIBF1120 in recurrent glioblastoma multiforme Cancer Research
06/04/2012
Abstract 3700: Anticancer effects and mechanisms of action of novel flavonoid didymin in neuroblastomas Cancer Research
06/04/2012
Abstract 3699: Adnab-9: A prospective stool biomarker for pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 3698: ODSH, a heparin derivative, enhances the efficacy of gemcitabine in a refractory human pancreatic tumor xenograft model Cancer Research