Medical Research Articles Published in June 2012

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06/04/2012
Abstract 5239: Use of bioscaffolds to study escape from tumor dormancy Cancer Research
06/04/2012
Abstract 5238: Impaired angiogenesis as a hallmark of prolonged tumor dormancy in a mouse model of human glioblastoma Cancer Research
06/04/2012
Abstract 5237: Interrogating cell heterogeneity and dormancy in prostate cancer disseminated tumor cells Cancer Research
06/04/2012
Abstract 5236: Potential loss of p53/p21 function in a murine lung adenocarcinoma cell line prevents TGF{beta}1-induced dormancy despite p38{alpha}/{beta} activation and DEC2 and p27 induction Cancer Research
06/04/2012
Abstract 5235: Uncovering tumor-host molecular and cellular interactions involved in tumor dormancy using microRNAs Cancer Research
06/04/2012
Abstract 5234: Microenvironmental signals dictate disseminated tumor cells (DTCs) fate through regulation of TGF{beta}II and p38{alpha} Cancer Research
06/04/2012
Abstract 5231: Zoledronic acid encapsulated into liposomes and nanoparticles: Enhanced antitumor activity in 3D-prostate carcinoma spheroids Cancer Research
06/04/2012
Abstract 5230: Improving the specificity of drugs which target the actin cytoskeleton for cancer therapy Cancer Research
06/04/2012
Abstract 5229: Apigenin inhibits TGF-beta-induced VEGF expression in human prostate carcinoma cells via Smad2/3 and Src/FAK/Akt signaling pathways Cancer Research
06/04/2012
Abstract 5228: Inhibition of myeloid cell PI3K{gamma} is a potential therapeutic approach to treat pancreatic cancer Cancer Research
06/04/2012
Abstract 5227: Multimodality approaches to treat hypoxic NSCLC tumor microenvironment Cancer Research
06/04/2012
Abstract 5226: Potential anti-tumor effect of a small molecule dipeptidyl peptidase inhibitor, 4175, in colorectal cancer Cancer Research
06/04/2012
Abstract 5225: Correlation between {alpha}v{beta}3 integrin expression, paclitaxel resistance and RGD-bearing conjugate efficacy Cancer Research
06/04/2012
Abstract 5224: Angiotensin-(1-7) inhibits proliferative and fibrotic signaling mechanisms in triple negative breast cancer Cancer Research
06/04/2012
Abstract 5223: The role of bone-marrow derived cells in the intestinal tumor microenvironment of apcmin/+ mouse on tumor response to inhibitors of thymidylate synthase Cancer Research
06/04/2012
Abstract 5222: A novel mechanism of microenvironment-mediated drug resistance in BRAF V600E melanoma with loss of PTEN Cancer Research
06/04/2012
Abstract 5221: A fusion toxin for the treatment of acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 5220: Dclk1 labels quiescent pancreatic progenitor and cancer initiating cells Cancer Research
06/04/2012
Abstract 5219: The role of MEK and Antizyme in keratinocyte stem cell expansion and differentiation Cancer Research
06/04/2012
Abstract 5218: A c-Myc driven threshold model of tumor initiating in glioblastoma Cancer Research
06/04/2012
Abstract 5217: RNA editing enzyme ADAR1 drives leukemia stem cell differentiation and self-renewal in chronic myeloid leukemia Cancer Research
06/04/2012
Abstract 5216: Impact of Stat3 deletion or activation on keratinocyte stem/progenitor cells Cancer Research
06/04/2012
Abstract 5215: EZH2-mediated STAT3 activation in glioblastoma Cancer Research
06/04/2012
Abstract 5214: Functional interaction between foxm1 and {beta}-catenin Cancer Research
06/04/2012
Abstract 5213: MDM2 at the crossroads of cell fate decisions in cerebellar development and medulloblastoma Cancer Research
06/04/2012
Abstract 5212: Irradiation-induced uPAR promotes stemness via Wnt/{beta}-catenin signaling in medulloblastoma cells Cancer Research
06/04/2012
Abstract 5210: Impact of tumor microenvironment on expansion of tumor initiating cells in breast cancer metastasis Cancer Research
06/04/2012
Abstract 5209: Prostate cancer progenitor cells have distinct DNA methylation profile which changes upon differentiation Cancer Research
06/04/2012
Abstract 5208: Overexpression of EZH2 increases multipotent mammary stem cell self-renewal and differentiation Cancer Research
06/04/2012
Abstract 5207: The chemokine 25 and chemokine receptor 9 axis suppresses colon cancer invasion and metastasis Cancer Research
06/04/2012
Abstract 5206: Systems biology identification of processes/pathways facilitating the development of high-grade serous ovarian cancer Cancer Research
06/04/2012
Abstract 5205: Iron metabolism informs glioblastoma stem cell maintenance Cancer Research
06/04/2012
Abstract 5204: Mechanisms of Notch4-Nodal regulation of the aggressive melanoma phenotype Cancer Research
06/04/2012
Abstract 5203: Lineage-specific mechanisms regulating PDGFR{alpha} oncogenic activity in glioblastoma Cancer Research
06/04/2012
Abstract 5202: Bone marrow-derived epithelial cells contribute to chronic skin inflammation and skin tumor formation in the mouse Cancer Research
06/04/2012
Abstract 5201: Suppression of WNT1 expression inhibits the maintenance and expansion of cancer stem cells in a mouse model of breast cancer Cancer Research
06/04/2012
Abstract 5200: Nestin regulates stem cell functions of pancreatic cancer cells Cancer Research
06/04/2012
Abstract 5199: Tumor vascularization by endothelial differentiation of endometrial cancer stem cells Cancer Research
06/04/2012
Abstract 5198: Elucidation of dynamic prostate epithelial hierarchy: Insights into transcriptional and epigenetic regulatory mechanisms Cancer Research
06/04/2012
Abstract 5197: Quantitative phosphorproteomics identified GPER-initiated PKA signal transduction event in breast cancer stem cell Cancer Research
06/04/2012
Abstract 5196: CDF inhibits cell migration by inactivating cancer stem cell markers, and expression of VEGF, IL-6 and miR-21 in human pancreatic and prostate cancer cells under hypoxic condition Cancer Research
06/04/2012
Abstract 5195: Ubiquitin carboxyl-terminal esterase L1 (UCHL1) in regulating cell cycle of neuroblastoma cancer stem-like cells Cancer Research
06/04/2012
Abstract 5194: Heterogenous expression of chemokine receptors in primary patient-derived GBM lines; association of CXCR3, CXCR4, and CXCR7 with a slow cycling sub-population Cancer Research
06/04/2012
Abstract 5193: The importance of primo vascular system (PVS) on cancer metastasis and therapeutic intervention: A new dimension of cancer stem cell Cancer Research
06/04/2012
Abstract 5192: Platelet derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity Cancer Research
06/04/2012
Abstract 5191: Periostin signaling in breast cancer stem cells Cancer Research
06/04/2012
Abstract 5189: N-cadherin promotes metastasis by enhancing motility through Akt3 suppression Cancer Research
06/04/2012
Abstract 5188: Altering cell attachment to growth substrate up-regulates growth differentiation factor 15 (GDF15) expression Cancer Research
06/04/2012
Abstract 5187: Urokinase plasminogen activator receptor (uPAR) and integrin {alpha}5{beta}1 regulate plasminogen activator inhibitor-1 (PAI-1) activity in medulloblastoma cells Cancer Research
06/04/2012
Abstract 5186: A new mode of integrin-Ecadherin cross talk that modulates invasion and metastasis Cancer Research
06/04/2012
Abstract 5185: Ovarian cancer cells induce fibronectin production in the peritoneal microenvironment through a TGF{beta}RI-dependent mechanism which promotes the early steps of metastasis Cancer Research
06/04/2012
Abstract 5184: Expression profiling of ECM proteins in advanced carcinoma of uterine cervix Cancer Research
06/04/2012
Abstract 5183: Raster-image-correlation spectroscopy of paxillin-GFP-expressing breast cancer cell in vitro and in vivo Cancer Research
06/04/2012
Abstract 5182: Real-time molecular imaging of {alpha}v-integrin GFP-expression in osteosarcoma cells in vitro and in vivo Cancer Research
06/04/2012
Abstract 5181: Dynamic cellular adhesivity of breast cancer cells conferred by CD44 varies with mesenchymal or epithelial phenotype Cancer Research
06/04/2012
Abstract 5179: Inhibition of U937-cell adhesion to human endothelial cells by glycosylated lysozyme mutants Cancer Research
06/04/2012
Abstract 5177: Molecular targeting of {alpha}v{beta}3 integrin by echistatin inhibits tumor progression and metastasis in osteosarcoma Cancer Research
06/04/2012
Abstract 5176: Imaging {alpha}v integrin-GFP during tumor blood vessel interaction in the chick CAM Cancer Research
06/04/2012
Abstract 5174: Novel signaling interactions of type XV collagen: Implications for tumor suppression Cancer Research
06/04/2012
Abstract 5173: The human homologue of frog (Xenopus laevis) anterior gradient protein promotes metastasis via regulation of cellular adhesion Cancer Research
06/04/2012
Abstract 5172: The role of vimentin in FAK-mediated cell adhesion and metastasis Cancer Research
06/04/2012
Abstract 5171: Restoration of fibronectin matrix assembly impedes invasion and reduces tumor-stromal cell affinity in prostate cancer Cancer Research
06/04/2012
Abstract 5170: Metabolism and cancer: The CD38-NAMPT connection in chronic lymphocytic leukemia Cancer Research
06/04/2012
Abstract 5169: Roles of lipogenesis in cancer stem-like cells at early stage of breast cancer Cancer Research
06/04/2012
Abstract 5167: Melatonin inhibition of linoleic acid transport and 13-HODE production in HeLa human cervical adenocarcinoma occurs via receptor-mediated signal transduction Cancer Research
06/04/2012
Abstract 5164: Using metabolomic flux to uncover new targets for the modulation of breast cancer metastasis Cancer Research
06/04/2012
Abstract 5163: Differential effects of IGF-2 on epithelial mesenchymal transition (EMT) in African- American and Caucasian breast cancer cell lines Cancer Research
06/04/2012
Abstract 5162: COX-2 downregulation protects SUM-149 cells following targeting of choline phospholipid metabolism Cancer Research
06/04/2012
Abstract 5161: Role of glutamine in cancer growth, invasion and progression: Therapeutic modulation of glutamine pathway Cancer Research
06/04/2012
Abstract 5160: Global metabolomic profiles distinguish malignant from non-malignant human mammary epithelial cell responses to endogenous p53 upregulation by MDM2 antagonism Cancer Research
06/04/2012
Abstract 5159: Investigation of local vitamin D metabolism in breast cancer using an ex vivo tissue explant system Cancer Research
06/04/2012
Abstract 5157: Prolactin plays a role in regulating fatty acid synthesis and metabolism in the prostate cancer cell line PC-3 Cancer Research
06/04/2012
Abstract 5156: Hyperglycemia enhances IGF-I responses and alters the AMPK activation profile that protects against metformin-induced growth inhibition in pancreatic cancer cells Cancer Research
06/04/2012
Abstract 5155: Suppression of gluconeogenesis in hepatocellular carcinoma by miR-23 directed downregulation of key gluconeogenic enzymes and the transcription factor PGC-1{alpha} Cancer Research
06/04/2012
Abstract 5154: Fatty acids mediated regulation of cancer metabolism Cancer Research
06/04/2012
Abstract 5153: Steroid receptor coactivator-2 mediates oncogenic reprogramming of cancer cell metabolism Cancer Research
06/04/2012
Abstract 5152: Targeting HIF1{alpha}-mediated metabolic alterations in pancreatic cancer Cancer Research
06/04/2012
Abstract 5151: Transcriptional regulation of the pyruvate dehydrogenase kinase Pdk2 by tumor suppressors Cancer Research
06/04/2012
Abstract 5150: Oncogene amplification in glioblastomas associates specifically with the increased expression of multiple glycolytic mediators Cancer Research
06/04/2012
Abstract 5149: CYLD downregulation induces aerobic glycolysis via mTOR pathway in human oral squamous cell carcinoma cells Cancer Research
06/04/2012
Abstract 5148: Amino acid transporters ASCT2 and LAT1 ubiquitously function in N-myc (+) epithelial and mesenchymal human HCC cells exhibiting a wide array of mTOR and glycolytic reliance for growth Cancer Research
06/04/2012
Abstract 5147: Glutamine addiction: Recognizing and harnessing the pathometabolic potential of Ras-mediated macropinocytosis Cancer Research
06/04/2012
Abstract 5146: Nicotinamide phosphoribosyl transferase (NAMPT) is over-expressed in Melanoma Cancer Research
06/04/2012
Abstract 5145: Glycolytic gene expression in ER-positive breast cancer tumors: Comparison with metastasis scores Cancer Research
06/04/2012
Abstract 5144: RNA-binding protein HuR supports post-transcriptional regulation of pancreatic cancer cell metabolism Cancer Research
06/04/2012
Abstract 5143: ErbB2 activation up-regulates glutaminase 1 expression via NF-{kappa}B pathway Cancer Research
06/04/2012
Abstract 5142: Up-regulation of glutamine synthetase attenuates the oncogenicity of wnt/{beta}-catenin signaling in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 5141: PI3K-mediated AMPK inactivation leads to a preneoplastic switch to glycolytic metabolism Cancer Research
06/04/2012
Abstract 5140: The functional c-Myc dependent polymorphisms of telomerase promoter control hTERT expression and are associated with telomere length Cancer Research
06/04/2012
Abstract 5139: Therapeutic targets for neuroblastoma by genome scale siRNA screens Cancer Research
06/04/2012
Abstract 5138: Development of a high-throughput screen for breast cancer metastatic potential Cancer Research
06/04/2012
Abstract 5137: A genome wide RNAi screen identify STAT3 activation as essential for ErbB2 mediated transforamtion of breast cancer cells Cancer Research
06/04/2012
Abstract 5136: Identification of sensitizers of platinum-based therapy in head and neck cancer using a functional genomics approach Cancer Research
06/04/2012
Abstract 5135: Functional genomic shRNA screens reveal that the canonical Wnt pathway protects lung cancer cells from EGFR inhibition Cancer Research
06/04/2012
Abstract 5134: The identification and characterization of genetic variations in lung adenocarcinomas in a Japanese population Cancer Research
06/04/2012
Abstract 5133: Copy number variation in 13q32.1 associated with esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 5132: Pooled shRNA screens conducted in vitro and in vivo identify genes that are essential for the growth and/or survival of human tumor cells Cancer Research
06/04/2012
Abstract 5131: Identification of the genes that chemosensitize hepatocellular carcinoma cells to interferon-{alpha} and 5-fluorouracil therapy Cancer Research
06/04/2012
Abstract 5130: Integrative approaches for the identification of therapeutic targets in basal like breast cancer from multi-level molecular data Cancer Research
06/04/2012
Abstract 5129: Identification of therapeutic targets for HPV-positive and HPV-negative head and neck cancers using high throughput RNAi screening Cancer Research
06/04/2012
Abstract 5128: Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data Cancer Research
06/04/2012
Abstract 5127: Characterization of lung cancers by integrated genomic and proteomic analysis Cancer Research
06/04/2012
Abstract 5126: Allele-specific effect of rs2294008 on mRNA and protein expression of the prostate stem cell antigen (PSCA) in human normal and tumor bladder tissue Cancer Research
06/04/2012
Abstract 5124: Genomic and proteomic characterization of tamoxifen sensitive and resistant MCF7 cells Cancer Research
06/04/2012
Abstract 5123: An integrated genomics approach to identify novel drivers of oncogenic pathway activity in human cancer Cancer Research
06/04/2012
Abstract 5122: Integral view of copy number alteration and commonly targeted genes in MDS found a new aspect of correlation and interrelationship with mutated components of the RNA splicing machinery Cancer Research
06/04/2012
Abstract 5121: Acquired inactivating ARID2 mutations in lung non small cell carcinoma Cancer Research
06/04/2012
Abstract 5120: Functional genetic screens identify a rare isoform of RABL3 as a modulator of paclitaxel resistance in ovarian cancer Cancer Research
06/04/2012
Abstract 5119: Frequent splicing pathway mutations and aberrant RNA splicing in myelodysplasia Cancer Research
06/04/2012
Abstract 5118: A functional genetic approach in patient-derived glioblastoma stem cells reveals pre-mRNA splicing components to be cancer-lethal gene targets Cancer Research
06/04/2012
Abstract 5117: Mutations of cohesin genes in myeloid malignancy Cancer Research
06/04/2012
Abstract 5116: Identification and rapid in vivo validation of a novel drug combination for treating melanoma Cancer Research
06/04/2012
Abstract 5115: Genetic signature of histiocytic sarcoma revealed by an unbiased genetic screen in mice Cancer Research
06/04/2012
Abstract 5114: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity Cancer Research
06/04/2012
Abstract 5113: Functional analysis of genomic variants identified through whole exome sequencing for susceptibility to lymphocytic leukemia Cancer Research
06/04/2012
Abstract 5112: Foxa1 and Foxa2 are essential for gender dimorphism in liver cancer Cancer Research
06/04/2012
Abstract 5110: Divergent gene expression profiles in HPV-positive and HPV-negative head and neck squamous cell carcinomas Cancer Research
06/04/2012
Abstract 5109: Identical cancer cell lines from Sanger & Broad CCLE programs sometimes differ Cancer Research
06/04/2012
Abstract 5108: A combined processing and assessment workflow for SNV and indel calling on exome sequencing of tumor samples Cancer Research
06/04/2012
Abstract 5107: Unravelling the complexity of individual cancer genomes Cancer Research
06/04/2012
Abstract 5106: A HHIP derived gene expression signature for the prediction of patient survival after adjuvant chemotherapy of pancreatic cancer Cancer Research
06/04/2012
Abstract 5105: Genetic alterations of the metastatic lesions in ovarian carcinoma Cancer Research
06/04/2012
Abstract 5104: Identification of key tumorigenic pathways in pancreatic adenocarcinoma patients using massively parallel DNA and RNA sequencing Cancer Research
06/04/2012
Abstract 5103: Transcriptional profiling in clear cell renal cell carcinoma (ccRCC). Focus on Czech Republic Cancer Research
06/04/2012
Abstract 5102: Identifying targets for melanoma therapy: Biological and clinical implications of BRAF L597 mutants Cancer Research
06/04/2012
Abstract 5100: Genomic profiling of triple negative breast cancer from South of Brazil Cancer Research
06/04/2012
Abstract 5099: Identification of complex oncogene signatures in human cancer specimens and cell lines Cancer Research
06/04/2012
Abstract 5098: Identification of copy number alterations associated with the progression and clinical outcomes of oral cavity squamous cell carcinoma Cancer Research
06/04/2012
Abstract 5097: Genome-wide analysis of DNA copy number aberrations in gastric cancer Cancer Research
06/04/2012
Abstract 5096: Targeted genome sequencing of 184 cancer-related genes for molecular targeted therapy in gastric cancer Cancer Research
06/04/2012
Abstract 5095: CGH+SNP microarrays for copy-neutral aberration detection in cancer research Cancer Research
06/04/2012
Abstract 5094: Genome-wide molecular profiles of undifferentiated pleomorphic sarcoma and leiomyosarcomas Cancer Research
06/04/2012
Abstract 5093: Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome Cancer Research
06/04/2012
Abstract 5092: Localized and disseminated histiocytic sarcoma complex: A canine model Cancer Research
06/04/2012
Abstract 5091: Proteomic study using a newly established metastatic lung cancer model Cancer Research
06/04/2012
Abstract 5089: Evaluation of BMP4 and BMP7 induced gene expression changes in breast cancer cells reveals time-dependent transcription patterns and a common synexpression group of genes Cancer Research
06/04/2012
Abstract 5088: Identification of effective genotype-selective drug combinations in melanoma Cancer Research
06/04/2012
Abstract 5087: UCSC Cancer Genomics Browser 2.0 Cancer Research
06/04/2012
Abstract 5085: TopModel: An online resource for predictive models in cancer Cancer Research
06/04/2012
Abstract 5084: Functional genomic classification of breast cancer using pooled lentivirus shRNA screens Cancer Research
06/04/2012
Abstract 5083: Analysis of head and neck cancer reveals recurrent copy number aberrations and molecular subtypes exhibiting distinct expression patterns of known oncogenes in the chr3q amplicon Cancer Research
06/04/2012
Abstract 5082: Determinants of clinical outcome in high grade serous ovarian cancer Cancer Research
06/04/2012
Abstract 5081: Comprehensive genomic analysis of primary CNS lymphomas (PCNSL) identifies multiple dysregulated genes involved in immune response, regulation of apoptosis, lymphocyte maturation and activation Cancer Research
06/04/2012
Abstract 5079: A genomic copy number biomarker to identify oral cancer patients at low risk for metastasis Cancer Research
06/04/2012
Abstract 5078: Identification of novel gene fusions by RNA-seq in gastric cancer Cancer Research
06/04/2012
Abstract 5077: Array CGH genomic profile of hereditary breast cancer tumors: Identification of tumor suppressor genes in deleted regions, determination of promoter hypermethylation and their protein expression in tumor biopsies Cancer Research
06/04/2012
Abstract 5076: Integrative genomic and transcriptomic analysis of metaplastic carcinomas of the breast Cancer Research
06/04/2012
Abstract 5075: Genome-wide analysis of DNA copy number variations in osteosarcoma Cancer Research
06/04/2012
Abstract 5074: Massively parallel DNA-sequencing of aggressive prostate cancer reveals disease heterogeneity and identifies targetable mutations Cancer Research
06/04/2012
Abstract 5073: Integrated genomics of high-resolution esophageal adenocarcinomas identify candidate driver genes in regions of large copy number aberrations Cancer Research
06/04/2012
Abstract 5072: Genome sequencing of metastatic colorectal carcinomas to identify potential targets for therapy in patients Cancer Research
06/04/2012
Abstract 5071: The genomic landscape of pancreatic cancer: from discovery to patient care Cancer Research
06/04/2012
Abstract 5070: Paired-end RNA-sequencing reveals novel fusion genes and SNVs in osteosarcoma Cancer Research
06/04/2012
Abstract 5069: Genomic profiles of primary non-small cell lung cancer (NSCLC) xenograft tumors identify distinct gene signatures associated with histological subtypes Cancer Research
06/04/2012
Abstract 5068: Identification of key tumorigenic pathways in never-smoker lung adenocarcinoma using massively parallel DNA and RNA sequencing and methylation profiling Cancer Research
06/04/2012
Abstract 5067: Exome sequencing reveals both DNA sequence and copy number changes in AML: Potential driver changes and mechanisms of drug resistance revealed from serial samples from the same patients Cancer Research
06/04/2012
Abstract 5066: Genome sequence and epigenome map of bladder cancer development from occult field effects Cancer Research
06/04/2012
Abstract 5065: Gene expression profiling of colon adenocarcinomas reveals six prototypic molecular subtypes with distinct clinical and molecular characteristics Cancer Research
06/04/2012
Abstract 5064: Cytogenetic and somatic characterization of myeloma tumors from a multi-ethnic cohort Cancer Research
06/04/2012
Abstract 5063: International Cancer Genome Consortium (ICGC) Cancer Research
06/04/2012
Abstract 5062: Integrated analysis of the whole exome sequencing (WES) identifies novel mutations and suggests patient selection hypothesis Cancer Research
06/04/2012
Abstract 5061: Genomic and functional analysis of Myxofibrosarcoma identifies novel prognostic markers and promising therapeutic targets Cancer Research
06/04/2012
Abstract 5060: Identification of somatic retrotransposon insertions across cancer types using RetroSeq Cancer Research
06/04/2012
Abstract 5059: Exome and targeted sequencing to discover and validate candidate genes in advanced and lethal prostate cancer Cancer Research
06/04/2012
Abstract 5058: Application of a high throughput cancer mutation profiling platform to clinical research Cancer Research
06/04/2012
Abstract 5057: Gene expression profile of chemoresponse of microdissected papillary serous tumors of the ovary identifies POLH and REV3L as potential therapeutic targets Cancer Research
06/04/2012
Abstract 5056: A glimpse into the somatic mutation landscape of melanoma through exome sequencing of 121 tumor-normal pairs Cancer Research
06/04/2012
Abstract 5055: Exploring the subclonal architecture of breast cancer Cancer Research
06/04/2012
Abstract 5054: Inferring mutational chronology in breast cancer by deep-sequencing tumor subpopulations Cancer Research
06/04/2012
Abstract 5053: MicroRNA expression profile of astrocytoma according to its malignant potential in Puerto Rican brain tumor samples Cancer Research
06/04/2012
Abstract 5052: MicroRNA alterations following radiation in melanoma Cancer Research
06/04/2012
Abstract 5050: MicroRNAs profiling in salivary rinse from patients with head and neck squamous cells carcinoma Cancer Research
06/04/2012
Abstract 5049: Serum miRNAs as an early marker for breast cancer Cancer Research
06/04/2012
Abstract 5048: Global microRNA expression array analysis and potential application in discovery of promising drugs for hematologic cancer Cancer Research
06/04/2012
Abstract 5047: Dysregulated microRNAs in cervical neoplasm Cancer Research
06/04/2012
Abstract 5046: miR-199a/125b inhibits tumor growth Cancer Research
06/04/2012
Abstract 5045: miR-10b mediates melanoma progression induced by BRAFV600E Cancer Research
06/04/2012
Abstract 5043: Comparison of the efficacy and analytical performance of isolation procedures for circulating plasma microRNAs Cancer Research
06/04/2012
Abstract 5042: A-AS1, a long non-protein coding RNA overexpressed in esophageal adenocarcinoma, influences cancer cell proliferation and apoptosis Cancer Research
06/04/2012
Abstract 5041: Characterization of the miR-125b1 promoter in breast cancer cell lines Cancer Research
06/04/2012
Abstract 5040: Aberrant DNA methylation of microRNAs in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 5039: Comparative analysis of miRNA in hormonal refractory prostate cancer Cancer Research
06/04/2012
Abstract 5038: Non-cording microRNA hsa-miR-199a expression in hepatocellular carcinoma correlates with patient survival Cancer Research
06/04/2012
Abstract 5037: Identifying differentially expressed microRNAs in retinoblastoma Cancer Research
06/04/2012
Abstract 5036: MicroRNA expression profiling potential for human breast cancer diagnosis using a bead-based microRNA-specific capturing method Cancer Research
06/04/2012
Abstract 5035: MicroRNA expression profiles classify renal cell carcinoma subtypes Cancer Research
06/04/2012
Abstract 5034: Healthy and cancerous serum RNA profiling by the novel RNA extraction reagent and highly sensitive DNA chip Cancer Research
06/04/2012
Abstract 5033: Relationship between microRNA expression and Gleason grading system in prostate cancer Cancer Research
06/04/2012
Abstract 5032: New insights of miR-221 and miR-222 cluster functions in Burkitt lymphoma. Cancer Research
06/04/2012
Abstract 5031: miR-21 targets TGF-{beta} Pathway in breast cancer Cancer Research
06/04/2012
Abstract 5030: Identification of the Her-2 expression-regulating miRNAs by microdissection and RT-PCR in breast cancer tissue Cancer Research
06/04/2012
Abstract 5029: Upregulation of miRNA27, miRNA125a and 125b in ERalpha-negative breast cancers Cancer Research
06/04/2012
Abstract 5026: Loss of microRNA-143/145 disturbs cell growth of cancers by impairing the MDM2-p53 feedback loop Cancer Research
06/04/2012
Abstract 5025: Regulation of miR-145 expression by Foxo3a, C/EBP-{beta} and p53 in cancer cells Cancer Research
06/04/2012
Abstract 5023: CpG pethylator phenotype (CIMP) methylation pattern in Puerto Ricans Hispanics colorectal cancer patients Cancer Research
06/04/2012
Abstract 5022: Immune biology drives cancer specific methylation profiles in blood Cancer Research
06/04/2012
Abstract 5021: Native accessible ChIP: A novel approach to interrogate protein-DNA interactions in accessible chromatin Cancer Research
06/04/2012
Abstract 5020: Genetic and epigenetic analysis of tumors in a zebrafish model of melanoma Cancer Research
06/04/2012
Abstract 5019: Reprogramming the cancer epigenome by "metabolic transduction" Cancer Research
06/04/2012
Abstract 5018: Genetic and epigenetic investigation of breast carcinoma arising in Lynch syndrome families Cancer Research
06/04/2012
Abstract 5017: DNA methylation array screening in salivary gland adenoid cystic carcinoma Cancer Research
06/04/2012
Abstract 5016: Epigenetics in renal cell carcinoma Cancer Research
06/04/2012
Abstract 5015: Regulation of histone modification and chromatin structure by p53-PADI4 pathway Cancer Research
06/04/2012
Abstract 5014: Differences in DNA methylation pattern of primary bladder tumours correlate with their metastatic potential Cancer Research
06/04/2012
Abstract 5013: CpG island shore methylation regulates caveolin-1 expression in breast cancer Cancer Research
06/04/2012
Abstract 5012: DNA methylation profiles of endometrial cancer and benign endometrium suggest differences by mismatch repair status and possible early detection markers Cancer Research
06/04/2012
Abstract 5010: Differences in DNA methylation between the African and European HapMap populations Cancer Research
06/04/2012
Abstract 5009: Identification of DNA methyltransferase target sites in cancer cells Cancer Research
06/04/2012
Abstract 5008: Genome-wide methylation and ovarian cancer survival Cancer Research
06/04/2012
Abstract 5006: High-throughput TR-FRET cellular assays for interrogating histone H3 methylation Cancer Research
06/04/2012
Abstract 5004: CpG island methylator phenotype in bladder cancer Cancer Research
06/04/2012
Abstract 5002: Comprehensive DNA methylation profiling of human hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 5000: Epigenomic profiling of oral cancer Cancer Research
06/04/2012
Abstract 4999: Genome-wide methylation array of human prostate tissues using illumina infunium 450K bead chip reveals distinct DNA methylation signatures with potential as clinical predictors Cancer Research
06/04/2012
Abstract 4998: Genome-wide methylation profiling in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4996: Genome-wide DNA methylation profiles in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4995: Glucose-regulated protein 78 regulates crosstalk between apoptosis and autophagy to determine antiestrogen responsiveness Cancer Research
06/04/2012
Abstract 4994: An integrated stress response activator causes cellular senescence and inhibits growth in multiple tumor cell types Cancer Research
06/04/2012
Abstract 4993: IRE1-XBP1 branch of UPR is involved in tumor angiogenesis Cancer Research
06/04/2012
Abstract 4992: SPARC overexpression induces ER stress leading to autophagy-mediated apoptosis in neuroblastoma cells Cancer Research
06/04/2012
Abstract 4991: Akt and AMPK modulate UPR activity and determine ER stress-induced cell death in response to 2-DG in ALL Cancer Research
06/04/2012
Abstract 4990: PP2A signaling is overridden by MEK/ERK activity leading to suppression of Bim and protection of melanoma cells from ER stress-induced apoptosis Cancer Research
06/04/2012
Abstract 4989: Selective inhibitors of the inositol-requiring enzyme 1 kinase domain Cancer Research
06/04/2012
Abstract 4988: The S-nitrosylation-mediated modification of p53 leads to altered DNA binding and associates with inactivity of p53 in human melanoma cells Cancer Research
06/04/2012
Abstract 4987: Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress Cancer Research
06/04/2012
Abstract 4986: Nuclear PRAS40 regulates the cellular response to nucleolar stress Cancer Research
06/04/2012
Abstract 4985: The essential role of eEF-2 kinase in determining fate of glioma cells under ER stress Cancer Research
06/04/2012
Abstract 4984: Phosporylation of eIF4E confer resistance to cellular stress Cancer Research
06/04/2012
Abstract 4983: Correlation telomere shortening in chronic lymphocytic leukemia cells with oxidative stress and dysregulation of shelterin proteins Cancer Research
06/04/2012
Abstract 4982: Aging-associated alterations in IL-7 receptor signaling and inflammation promote declining B-lymphopoiesis and increased leukemogenesis Cancer Research
06/04/2012
Abstract 4981: NADPH oxidase is a novel target of delphinidin to inhibits UVB-induced MMP-1 expression in human dermal fibroblasts Cancer Research
06/04/2012
Abstract 4980: Age dependent carcinogenic susceptibility of rat liver is related to potential of gap junctional intercellular communication Cancer Research
06/04/2012
Abstract 4979: Co-operative role for Notch and fibroblast growth factor FGF2 signaling pathways in maintaining malignant phenotype of neuroblastoma: Potential targets for neuroblastoma growth inhibition. Cancer Research
06/04/2012
Abstract 4978: The C/EBPbeta isoform, liver-enriched inhibitory protein (LIP) induces cell death in breast cancer cell lines Cancer Research
06/04/2012
Abstract 4976: Telomerase-specific replication-selective virotherapy combined with radiation therapy for oral squamous cell carcinoma cells Cancer Research
06/04/2012
Abstract 4974: Metformin has an anti-cancer effect by repressing TWIST/N-cadherin signaling Cancer Research
06/04/2012
Abstract 4973: Telomerase-specific replication-selective oncolytic viruses for adenoid cystic carcinoma cell lines Cancer Research
06/04/2012
Abstract 4972: Phosphorylation of caspase-3 and caspase-7 by p21-activated protein kinase (PAK)2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines Cancer Research
06/04/2012
Abstract 4971: The oncometabolite (R)-2-hydroxyglutarate modulates stress-induced caspase activity in glioma cells Cancer Research
06/04/2012
Abstract 4970: Convergence of protein kinase and caspase signaling: A mechanism for pathological rewiring of survival pathways by protein kinase CK2 Cancer Research
06/04/2012
Abstract 4968: Phosphorylation of caspase-8 (Thr263) by ribosomal S6 kinase 2 (RSK2) mediates caspase-8 ubiquitination and stability Cancer Research
06/04/2012
Abstract 4967: Altholactone induces caspase dependent and independent apoptosis of human colorectal cancer cells Cancer Research
06/04/2012
Abstract 4966: The anti-apoptotic activity of caspase-2 short isoform is regulated by XPC protein Cancer Research
06/04/2012
Abstract 4965: Oncoprotein PMLRAR{alpha} directly suppresses Fas-mediated apoptosis through forming an apoptotic inhibitory complex with c-FLIP in vivo Cancer Research
06/04/2012
Abstract 4964: Mutations of cysteine residues in Bcl-2 suppress hydrogen peroxide-induced apoptosis of human lung cancer cells through ERK1/2 interaction Cancer Research
06/04/2012
Abstract 4963: Tanshinone IIA induces JNK-dependent intrinsic apoptosis via suppressing astrocyte-elevated gene 1 expression in chronic myelogenous leukemia KBM-5 cells Cancer Research
06/04/2012
Abstract 4962: TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells Cancer Research
06/04/2012
Abstract 4961: In human breast cancer cells thyroid hormone signaling overshadows estrogen signaling on SMP30 gene leading to induction of apoptosis Cancer Research
06/04/2012
Abstract 4960: The role of YY1 in paclitaxel-induced cytotoxicity in epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 4959: Osteoprotegerin mediates resistance to TRAIL-induced apoptosis in pancreatic ductal adenocarcinoma Cancer Research
06/04/2012
Abstract 4958: Identification of cis-regulatory elements in a BIM deletion polymorphism that regulate splicing and generation of non-apoptotic BIM isoforms Cancer Research
06/04/2012
Abstract 4957: Mixed Lineage Kinase 3 mediates vanadium-induced cell death in cancer cells Cancer Research
06/04/2012
Abstract 4956: Regulation of anoikis by DBC1 (Deleted-In-Breast Cancer 1) through NF-kB Cancer Research
06/04/2012
Abstract 4955: TIMP-1 inhibits apoptosis in lung adenocarcinoma cells via Bcl-2 interaction Cancer Research
06/04/2012
Abstract 4954: The expression of X-linked inhibitor of apoptosis in human oral squamous cell carcinoma and its relationship with clinical factors Cancer Research
06/04/2012
Abstract 4953: Interaction of vitamin E compounds with docosahexaenoic acid on induction of apoptosis in human triple negative breast cancer cells Cancer Research
06/04/2012
Abstract 4952: Persistent expression of Nqo1 by p62-mediated Nrf2 activation facilitates p53-dependent mitotic catastrophe Cancer Research
06/04/2012
Abstract 4949: A dynamic TGFBR3-JUND expression circuit in single basal-like breast epithelial cells Cancer Research
06/04/2012
Abstract 4948: Uncovering microRNA and transcription factor-mediated regulatory network in glioblastoma Cancer Research
06/04/2012
Abstract 4947: Analysis of structural mutations in cancer genomes Cancer Research
06/04/2012
Abstract 4946: Control of cellular proliferation by ERK: A quantitative analysis in single cells Cancer Research
06/04/2012
Abstract 4945: Targeting ErbB3-addicted cancers across the HER2 spectrum Cancer Research
06/04/2012
Abstract 4944: Crosstalk between NF{kappa}B and STAT3 in human multiple myeloma cells (U266) Cancer Research
06/04/2012
Abstract 4943: Genetically engineered osteoprotegerin for multiple myeloma osteolytic bone damage Cancer Research
06/04/2012
Abstract 4942: Can three-dimensional cell cultures be used to predict in vivo drug response and synergistic combinations Cancer Research
06/04/2012
Abstract 4940: Activated signaling mechanism of glioblastoma recurrence derived from genetics, epigenetics, and genomics abnormalities Cancer Research
06/04/2012
Abstract 4939: A characterization of pathway aberrations across human cancers Cancer Research
06/04/2012
Abstract 4938: A global landscape of transcriptional interactions and regulations in lung cancer Cancer Research
06/04/2012
Abstract 4937: Factors in NSCLC stage and outcome: Integrated genome-wide study Cancer Research
06/04/2012
Abstract 4936: Network signatures of survival in glioblastoma multiforme Cancer Research
06/04/2012
Abstract 4769: Combinatorial effect of thermally targeted p21 polypeptide and bortezomib in prostate cancer Cancer Research
06/04/2012
Abstract 4768: Design and development of selective sphingosine kinase 2 inhibitors Cancer Research
06/04/2012
Abstract 4767: Reaction of singlet oxygen with hydrazone prodrugs for the photochemical release of N-nitrosoamine drugs Cancer Research
06/04/2012
Abstract 4766: The use of deuterium isotope effects to shift the partitioning of cyclophosphamide and ifosfamide among competing, P450-dependent, oxidative pathways Cancer Research
06/04/2012
Abstract 4765: Synthesis and evaluation of nonclassical 6-substituted pyrrolo[2,3-d]pyrimidine antifolates: Role of terminal amino acid moiety in membrane transport and antitumor activity. Cancer Research
06/04/2012
Abstract 4764: Targeting formin autoinhibition to construct cell infrastructure Cancer Research
06/04/2012
Abstract 4763: Targeting p300 for inhibiting triple negative breast cancer Cancer Research
06/04/2012
Abstract 4762: Effect of the phytochemical crinumaquine on prostate and prostate cancer cell lines Cancer Research
06/04/2012
Abstract 4760: Inhibition of c-myc by the triterpenoid celastrol Cancer Research
06/04/2012
Abstract 4759: Drugging the undruggable: Small molecule inhibition of the Ras oncoprotein Cancer Research
06/04/2012
Abstract 4758: Self-assembled superparamagnetic iron oxide nanoparticles for targeted cancer therapy Cancer Research
06/04/2012
Abstract 4757: Design and optimization of linked nucleic acid (LNA) probes to detect the c-MYC G-quadruplex Cancer Research
06/04/2012
Abstract 4756: YM155 suppresses survivin expression by disrupting the ILF3/p54nrb transcription factor complex Cancer Research
06/04/2012
Abstract 4755: The role of a pair of cysteine residues in the redox properties of human ribonucleotide reductase small subunits hp53R2 and hRRM2 Cancer Research
06/04/2012
Abstract 4754: Quantitative characterization of calmodulin and Fas death domain interactions Cancer Research
06/04/2012
Abstract 4753: Targeting nucleotide excision repair: Chemical synthetic lethality and biology-based combination therapy Cancer Research
06/04/2012
Abstract 4752: Selective inhibition of cancer metastasis with a novel small therapeutic molecule Cancer Research
06/04/2012
Abstract 4751: Structure and inhibition of mitogen-activated protein kinase kinase 4 (MEK4): A prostate cancer pro-invasion protein Cancer Research
06/04/2012
Abstract 4750: Overcoming DDP resistance using folic acid-heparin-DDP nanoparticles Cancer Research
06/04/2012
Abstract 4749: Insights into the molecular mechanism of HSP90 binding of methoxy-substituted resorcinylic isoxazole amide inhibitors reveal different isoform selectivity profiles Cancer Research
06/04/2012
Abstract 4747: Redirecting the endogenous immune response against prostate cancer using an antibody-recruiting small molecule Cancer Research
06/04/2012
Abstract 4746: Structural studies of human glioma pathogenesis-related protein 1(GLIPR1) Cancer Research
06/04/2012
Abstract 4745: Multivalent dendrimeric peptides as new biomarker probes for the detection of cancer metastasis Cancer Research
06/04/2012
Abstract 4744: Development of an immunoproteasome fluorescent substrate: A functional proteomics tool Cancer Research
06/04/2012
Abstract 4743: Exosomes in motion: Visualizing cancer metastasis via the Synaptotagmin C2B domain Cancer Research
06/04/2012
Abstract 4742: Comprehensive epitope mapping of antibodies against CXCR4 and Claudin-4 by Shotgun Mutagenesis Cancer Research
06/04/2012
Abstract 4741: Development of a novel therapeutic agent for breast cancer based on a new pathway analysis of triple-negative breast cancer Cancer Research
06/04/2012
Abstract 4740: Establishment of P53 mutant type specific spontaneous lung tumor in transgenic mice for treatment Cancer Research
06/04/2012
Abstract 4739: miR-627 and histone demethylase JMJD1A as new therapeutic targets in colon cancer Cancer Research
06/04/2012
Abstract 4738: The early response protein EGR-1 mediates vitamin E {gamma}-tocotrienol-induced apoptosis in pancreatic cancer cells Cancer Research
06/04/2012
Abstract 4737: Resveratrol targeting of carcinogen-induced brain endothelial cell inflammation biomarkers MMP-9 and COX-2 is Sirt1-independent Cancer Research
06/04/2012
Abstract 4736: N-myc downstream regulated gene 1: A novel mediator of hypoxia-driven chemoresistance in glioblastoma Cancer Research
06/04/2012
Abstract 4735: Epigenetic modification of the PI3K/Akt/HIF1{alpha} pathway in lymphoma cells by HDAC inhibition Cancer Research
06/04/2012
Abstract 4734: Genes cooperatively downregulated by combined mTOR/histone deactylase (HDAC) inhibition are overexpressed in myeloma patients with lower survival Cancer Research
06/04/2012
Abstract 4733: Function of cytoplasmic histone deacetylase 5 is required for HIF-1{alpha} stability Cancer Research
06/04/2012
Abstract 4731: Cytotoxic versus cytostatic effects in tumor models by spiro-oxindole-based modulators of the MDM2-p53 interaction Cancer Research
06/04/2012
Abstract 4730: Inhibition of the p53-HDMX interaction sensitizes melanoma to chemotherapy Cancer Research
06/04/2012
Abstract 4728: Fatostatin, a novel SREBP inhibitor, suppresses cell growth and induces apoptosis in prostate cancer Cancer Research
06/04/2012
Abstract 4727: Antitumor activity of the MDM2 antagonist, RG7112 Cancer Research
06/04/2012
Abstract 4726: Novel small molecule inhibitors of MDM2/4-p53 interaction, YH264 and its ethyl ester YH263: preclinical evaluation Cancer Research
06/04/2012
Abstract 4725: Inhibition of the Hedgehog signaling pathway - a new target in treatment for children with neuroblastoma Cancer Research
06/04/2012
Abstract 4724: Anti-tumor effects of SC-2001, a novel STAT3 inhibitor, in breast cancer cells Cancer Research
06/04/2012
Abstract 4723: HO-3867, a STAT3 inhibitor induces G2/M arrest and apoptosis in BRCA1-mutated ovarian cancer cells Cancer Research
06/04/2012
Abstract 4722: Targeted inhibition of SIRT1 histone deacetylase by small-molecule inhibitor Tenovin-1 imparts significant anti-proliferative effects in human melanoma cells Cancer Research
06/04/2012
Abstract 4721: Adaptation to histone deacetylase inhibitors attenuates cancer cell growth Cancer Research
06/04/2012
Abstract 4720: Histone deacetylases as promising drug targets for treatment of esophageal squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4719: The HDAC inhibitor ITF2357 blocks c-Myc expression via microRNA modulation and cap-dependent translation inhibition in human Burkitt's lymphoma Cancer Research
06/04/2012
Abstract 4718: Potent preclinical antitumor effects induced by pan-histone deacetylase inhibitor panobinostat in combination with sorafenib in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4717: The anti-leukemic efficacy of the histone deacetylase inhibitor phenylbutyrate (PB): Reversal of epigenetic inactivation of WNT signalling pathway by PB Cancer Research
06/04/2012
Abstract 4716: The antitumor effect of HDAC inhibitor Tenovin-6 for gastric cancer cells Cancer Research
06/04/2012
Abstract 4715: Activation of lytic cycle of Epstein-Barr virus by suberoylanilide hydroxamic acid affects apoptosis and tumor growth suppression of nasopharyngeal carcinoma Cancer Research
06/04/2012
Abstract 4713: Detrimental effects of a histone deacetylase inhibitor on human lymphocytes Cancer Research
06/04/2012
Abstract 4712: Target epigenetic regulation at a specific genomic region by using DNA binding molecules and HDACi Cancer Research
06/04/2012
Abstract 4711: Epigenetic modulation restores expression of functional progesterone receptor in endometrial cancer cells Cancer Research
06/04/2012
Abstract 4710: Deactylases in multiple myeloma: Expression, inhibition and resistance to inhibition Cancer Research
06/04/2012
Abstract 4709: Combined mitogen-activated protein kinase pathway inhibition with short-term romidepsin treatment induces proapoptotic Bim and cell death in BRAF mutant cancers Cancer Research
06/04/2012
Abstract 4708: Short-term romidepsin treatment combined with mitogen-activated protein kinase and phosphatidylinositol 3-kinase inhibition causes increased Bim expression and cell death in KRAS mutant cell lines Cancer Research
06/04/2012
Abstract 4707: Inhibition of autophagy overcomes acquired resistance to vorinostat Cancer Research
06/04/2012
Abstract 4706: Resveratrol potentiates the lethality of HDAC inhibitors in acute myelogenous leukemia cells Cancer Research
06/04/2012
Abstract 4705: Dual targeting of epigenetic pathways and NF-kappaB in diffuse large B-cell lymphoma Cancer Research
06/04/2012
Abstract 4704: Effects of the HDAC inhibitor S78454/PCI-24781 on ER signalling in ER{alpha}-positive antiestrogen-sensitive and -resistant breast cancer cells Cancer Research
06/04/2012
Abstract 4703: SAHA downregulation of HuR expression is responsible for reduction of cyclin D1 mRNA stability and cell transformation by EGF in Cl41 cells Cancer Research
06/04/2012
Abstract 4702: Antitumor activity of a novel histone deacetylase inhibitor S78454 in EBV-associated nasopharyngeal carcinoma Cancer Research
06/04/2012
Abstract 4701: Tasquinimod suppresses the adaptive stress response within sites of prostate cancer via disrupting zinc-dependent Histone Deacetylase 4 signaling. Cancer Research
06/04/2012
Abstract 4700: A novel selective EZH2 inhibitor exhibits anti-tumor activity in lymphoma with EZH2 activating mutations Cancer Research
06/04/2012
Abstract 4699A: Hedgehog signaling (HH/Gli) transcriptionally regulates hTERT gene expression in human cancer cells Cancer Research
06/04/2012
Abstract 4699: A siRNA high-throughput screening identified Wee1 as determinant of Chk1 inhibitor sensitivity Cancer Research
06/04/2012
Abstract 4698: Inhibition of histone deacetylase (HDAC) 3 induces hyperacetylation and inhibition of nuclear heat shock protein (hsp) 90 leading to depletion of ATR and CHK1 with sensitization to DNA damage in breast and cervical cancer cells Cancer Research
06/04/2012
Abstract 4697: Identification, characterization and effects of inhibitors of the human Apurinic/Apyrimidinic Endonuclease 1 (APE1) protein Cancer Research
06/04/2012
Abstract 4696: Expression of the DNA repair protein UNG predicts lung cancer sensitivity to pemetrexed Cancer Research
06/04/2012
Abstract 4695: TGF-{beta} enforces genomic instability in liver cancers Cancer Research
06/04/2012
Abstract 4694: The small molecule CHK1/CHK2 inhibitor PF-0477736 (Pfizer) demonstrates single agent activity in diffuse large B-cell lymphoma Cancer Research
06/04/2012
Abstract 4693: The putative DNA/RNA Helicase Schlafen-11 sensitizes cancer cells to topoisomerase I inhibitors Cancer Research
06/04/2012
Abstract 4692: ABT-888 synergizes treatment of colon cancer cell lines with irinotecan Cancer Research
06/04/2012
Abstract 4691: Rationale for combining PARP inhibitors with topotecan or irinotecan: taking advantage of the alternative DNA repair pathways involving XPF-ERCC1 and PARP-TDP1 Cancer Research
06/04/2012
Abstract 4690: PARP inhibition increases sensitivity to cisplatin in ERCC1-low non-small cell lung cancers Cancer Research
06/04/2012
Abstract 4689: Stabilization of PARP-DNA complexes plays a critical role for the cytotoxic effects of the PARP inhibitors, veliparib and oliparib Cancer Research
06/04/2012
Abstract 4687: DNA polymerase <= inhibitors enhance the chemotherapeutic efficacy of Temozolomide by increasing senescence in colon cancer cells Cancer Research
06/04/2012
Abstract 4686: Synergistic effect of olaparib (AZD2281) with combination of cisplatin on PTEN-deficient lung cancer cell lines Cancer Research
06/04/2012
Abstract 4685: Discovery and characterization of nitroaspirin (NCX-4016) as a powerful and clinically relevant inhibitor of human MGMT for increasing the efficacy of alkylating agents Cancer Research
06/04/2012
Abstract 4684: Synthetic lethal interaction between EGFR and PARP inhibition Cancer Research
06/04/2012
Abstract 4683: Poly (ADP-ribose) polymerase inhibitor LT-626: Sensitivity correlates with MRE11 and synergizes with cisplatin, oxaliplatin, and SN-38 in colorectal cancer cells Cancer Research
06/04/2012
Abstract 4682: Compensatory activation of alternative DNA repair pathways following exposure to the PARP Inhibitor ABT-888 in vitro and in patients with solid malignancies Cancer Research
06/04/2012
Abstract 4681: Inhibition of poly (ADP-ribose) polymerase-1 (PARP-1) as a strategy for targeted therapy in Ewing's sarcoma Cancer Research
06/04/2012
Abstract 4680: DNA dependent protein kinase as a new molecular target for treatment of non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4679: Betulinic acid inhibits deubiquitinases to increase the degradation of pro-survival proteins and enhance prostate cancer-specific apoptosis Cancer Research
06/04/2012
Abstract 4678: Silencing of TIMELESS induces growth suppression, apoptosis and enhanced cytotoxicity of cisplatin in H157 lung cancer cells Cancer Research
06/04/2012
Abstract 4677: Slug is a potential target to restore transforming growth factor-{beta} mediated apoptosis in lung cancer cells Cancer Research
06/04/2012
Abstract 4676: A novel APIM-motif comprising peptide drug potentiates the action of several chemotherapeutic drugs by blocking the interaction between PCNA and key proteins involved in DNA repair, apoptosis and cell cycle control Cancer Research
06/04/2012
Abstract 4675: Fatty acid metabolism is a possible target for treatment of cyclin D1 over-expressing mantle cell lymphoma Cancer Research
06/04/2012
Abstract 4673A: DAPK-mediated phosphorylation of HSF1 enhances apoptosis level upon TNF in colorectal carcinoma cells Cancer Research
06/04/2012
Abstract 4673: The anti-proliferative effects of non-steroidal anti-inflammatory drugs (NSAIDs) diclofenac and indomethacin in ovarian cancer cells Cancer Research
06/04/2012
Abstract 4672: Anti-angiogenic effects of zoledronic acid on osteotropic breast cancer cells Cancer Research
06/04/2012
Abstract 4671: Assessment of molecular processes relative to DNA damage response using primary human hematopoietic cells exposed to high-dose chemotherapy Cancer Research
06/04/2012
Abstract 4670: Identification of common genetic variants contributing to cisplatin-induced apoptosis and cytotoxicity in lymphoblastoid cell lines Cancer Research
06/04/2012
Abstract 4669: A combination of raloxifene and gefitinib potentiates the cytotoxicity and induces apoptosis in estrogen receptor negative breast cancer cell lines Cancer Research
06/04/2012
Abstract 4668: Patient AML cells and AML cell lines are highly sensitive to CNDAC, the active form of sapacitabine Cancer Research
06/04/2012
Abstract 4667: Simultaneous Chk1 and MEK1/2 inhibition circumvents Mcl-1 anti-apoptotic function and bortezomib resistance in human multiple myeloma cells Cancer Research
06/04/2012
Abstract 4666: Anti-leukemic activity of a novel histone deacetylase inhibitor, CG200745, via induction of mitochondrial dysfunction in acute myeloid leukemia Cancer Research
06/04/2012
Abstract 4665: Sensitization of head and neck cancer cells toward cisplatin by inhibition of autophagy Cancer Research
06/04/2012
Abstract 4664: Co-treatment of cancer cells with DNA damaging drugs and quercetin suppresses cell growth independent of p21 and Bax induction Cancer Research
06/04/2012
Abstract 4663: The cyclooxygenase-2 inhibitor, celecoxib, suppresses proliferation and induces apoptosis in endometrial cancer cells Cancer Research
06/04/2012
Abstract 4662: Shikonin causes cancer cell death by inducing mitochondrial dysfunction Cancer Research
06/04/2012
Abstract 4661: Levels of C22:0- and C24:0-dihydroceramide correlate with cytotoxicity in T-cell acute lymphoblastic leukemia cell lines Cancer Research
06/04/2012
Abstract 4660: Antiproliferative effects of antagonists of Inhibitor of Apoptosis Proteins (IAPs) in human cancer cells Cancer Research
06/04/2012
Abstract 4659: Switch between Apoptosis and Autophagy induced by 4-HPR-driven ROS: The role of DJ-1 and it's different oxidative modifications Cancer Research
06/04/2012
Abstract 4658: Delta9-Tetrahydrocannabinol induces apoptosis via Cannabinol Receptor 1 and modulates methylation of oncogenes and tumorsuppressors in blasts derived from patients with acute lympoblastic or myeloid leukemia Cancer Research
06/04/2012
Abstract 4657: Differential regulation of autophagy vs. apoptosis as a potentially unique mechanism of cancer cell specific radiosensitization with fluoxetine Cancer Research
06/04/2012
Abstract 4656: Targeting Sp1 and survivin for potential ovarian cancer therapy: Comparative assessment of anti-cancer NSAID tolfenamic acid and cisplatin Cancer Research
06/04/2012
Abstract 4655: Aplidin induces a non-canonical ER stress response in HeLa cells response in HeLa cells Cancer Research
06/04/2012
Abstract 4654: Docosahexaenoic acid induces autophagy through reactive oxygen species /mTOR pathway in p53 mutant cancer cells Cancer Research
06/04/2012
Abstract 4652: The autophagy-senescence connection in chemotherapy of breast tumor cells; senescence accelerated by autophagy but not dependent on autophagy Cancer Research
06/04/2012
Abstract 4651: Sorafenib and its derivatives induce apoptosis and autophagy in canine mammary tumor cells Cancer Research
06/04/2012
Abstract 4649: Nbk/Bik induced by flavopiridol switches GX15-070-induced autophagy to apoptosis in human multiple myeloma cells Cancer Research
06/04/2012
Abstract 4648: In vitro characterization of spiro-oxindole-based modulators of the MDM2-p53 interaction and their interspecies selectivity. Cancer Research
06/04/2012
Abstract 4647: Caspase-dependent post-translational modulation of Mcl-1 by ABT-737 in acute lymphoblastic cell lines Cancer Research
06/04/2012
Abstract 4646: Toward engineering of novel anticancer bio-agents Cancer Research
06/04/2012
Abstract 4645: Preclinical development of RFF-1, a novel rational designed CXCL12 mimetic drug Cancer Research
06/04/2012
Abstract 4644: A novel strategy for targeted drug delivery to the tumor vasculature by radiation-induced receptor expression on endothelial cells Cancer Research
06/04/2012
Abstract 4642: Combined glycolytic inhibition and anti-vascular treatment in retinoblastoma: Novel strategy for tumor control avoids chemotherapy Cancer Research
06/04/2012
Abstract 4641: Hypoxia activated pro-drug TH-302 induces hypoxia-dependent anti-leukemia activity in vitro and in vivo Cancer Research
06/04/2012
Abstract 4640: Development of antibody-drug conjugate technology based on novel DNA-interacting agents and unique linker technology Cancer Research
06/04/2012
Abstract 4638: Suppression of tumorigenicity by targeting anterior gradient-2 (AGR2) through multiple epitopes binding of the monoclonal antibody 18A4 Cancer Research
06/04/2012
Abstract 4637: Cell penetrating antibodies for intracellular targets: Expanding the antibody-based treatments for cancer Cancer Research
06/04/2012
Abstract 4636: Novel immunoRNases comprising multiple copies of ranpirnase display potent cytotoxicity in human breast cancer cell lines expressing Trop-2 Cancer Research
06/04/2012
Abstract 4635: Development of monoclonal antibodies against the GPCR CXCR4 and the ion channel Hv1 using virus-like particles Cancer Research
06/04/2012
Abstract 4634: Engineered cysteine drug conjugates show potency and improved safety Cancer Research
06/04/2012
Abstract 4633: Polyacetal-based immunoconjugates: Next-generation ADCs with high drug loading, alternative payloads, and alternative protein recognition scaffolds Cancer Research
06/04/2012
Abstract 4632: Phosphatidylserine-targeting 'betabodies' for the treatment of cancer Cancer Research
06/04/2012
Abstract 4631: Anti-CD70 antibody-drug conjugates containing pyrrolobenzodiazepine dimers demonstrate robust antitumor activity Cancer Research
06/04/2012
Abstract 4630: Integrin {alpha}V{alpha}6 is expressed on multiple solid tumors and is a potential therapeutic target for auristatin-based antibody-drug conjugates Cancer Research
06/04/2012
Abstract 4629: Tumor penetration and retention of different sized FGFR4 targeting scaffolds Cancer Research
06/04/2012
Abstract 4628: Anti-tumor activity and pharmacokinetics of the anti-FOLR1-maytansinoid conjugate IMGN853 is maintained over a wide range of maytansinoid-to-antibody ratios Cancer Research
06/04/2012
Abstract 4913: A quantitative integrated systems biology approach for modeling cell cycle pathways in normal and tumor cells Cancer Research
06/04/2012
Abstract 4912: Systematic, comparative network analysis on non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4911: Systems level network analysis of NCI60 cell lines by alignment of protein pathway activation modules with multiple -omic data fields and therapeutic response signatures Cancer Research
06/04/2012
Abstract 4910: Apoptotic effects of curcumin and bleomycin alone or in combination on malignant testicular germ cells Cancer Research
06/04/2012
Abstract 4909: Calcitriol and arsenic trioxide synergistically inhibited proliferation of HL-60 cell line mainly through apoptosis pathway Cancer Research
06/04/2012
Abstract 4908: The apoptotic response of the triple negative breast cancer cell line HCC1806 to chemotherapeutics Cancer Research
06/04/2012
Abstract 4907: Effect of arsenic trioxide on cholangiocarcinoma: Use of an in vitro test and an in vivo xenograft model Cancer Research
06/04/2012
Abstract 4906: Tamoxifen-mediated apoptosis relationship with ER{alpha}36 in gastric cancer cell BGC823 Cancer Research
06/04/2012
Abstract 4905: The BH3 mimetic navitoclax (ABT-263) selectively induces apoptosis in cholangiocarcinoma-associated fibroblasts thereby reducing tumor growth Cancer Research
06/04/2012
Abstract 4904: Acetaminophen enhances the chemotherapeutic effect of cisplatin and paclitaxel on human ovarian carcinoma cells in vitro Cancer Research
06/04/2012
Abstract 4903: D-alpha-tocopheryl polyethylene glycol succinate (TPGS) induces apoptosis and cell cycle arrest selectively in breast cancer cells by targeting aberrantly activated pathways engaging survivin signaling Cancer Research
06/04/2012
Abstract 4902: Targeting APC mutant colon cancer cells by chloroquine Cancer Research
06/04/2012
Abstract 4901: Impact of the TGF-{beta}1 isoform on p53 signalling in ovarian cancer cell lines in response to cisplatin Cancer Research
06/04/2012
Abstract 4900: Bortezomib induces G2-M arrest through ROS-inducible phosphorylation of ATM independent on genotypes of KRAS in human colon cancer cells Cancer Research
06/04/2012
Abstract 4899: Altered receptor glycosylation confers cisplatin resistance in ovarian and colon cancer cells Cancer Research
06/04/2012
Abstract 4898: Methylseleninic acid potentiates multiple types of cancer cells to ABT-737-induced apoptosis involving Mcl-1, AKT-Bad, and mitochondrial cascade Cancer Research
06/04/2012
Abstract 4897: Involvement of Akt isoforms in chemoresistance of carcinoma endometrial cells Cancer Research
06/04/2012
Abstract 4896: Synergistic anti-tumor activity of CDK4/6 inhibitor combined with paclitaxel in NSCLC cells harboring mutant KRAS Cancer Research
06/04/2012
Abstract 4895: Caveolin-1 modulates docetaxel activity by inducing p53 expression in breast cancer. Cancer Research
06/04/2012
Abstract 4894: Effect of lysosome destabilization on response to ceramide in prostate cancer cells over-expressing acid ceramidase Cancer Research
06/04/2012
Abstract 4893: XIAP downregulation accompanies inhibition of melanoma xenograft growth by mebendazole Cancer Research
06/04/2012
Abstract 4892: EBV infectivity determines sensitivity to bortezomib in hematopoietic malignancy cells Cancer Research
06/04/2012
Abstract 4891: Radiation enhances the efficacy of Bcl-2 and Bcl-XL inhibition in small cell lung cancer: A new concept of using radiation for targeted therapy through contextual oncogene addiction Cancer Research
06/04/2012
Abstract 4890: Arsenic trioxide induces apoptosis through the activation of ASK1 and is enhanced by a thioredoxin reductase inhibitor Cancer Research
06/04/2012
Abstract 4889: ERa-targeted therapy in ovarian cancer cells using novel Estradiol-Platinum(II) hybrids Cancer Research
06/04/2012
Abstract 4888: Decitabine and vorinostat cooperate to sensitize metastatic human colon carcinoma cells to Fas-mediated apoptosis Cancer Research
06/04/2012
Abstract 4887: Curcuminoid CLEFMA induces autophagy-associated apoptosis in lung cancer Cancer Research
06/04/2012
Abstract 4886: PTHrP sensitizes breast cancer cells to TRAIL-induced apoptosis Cancer Research
06/04/2012
Abstract 4885: mTOR complex 2 is involved in regulation of c-FLIP stability and sensitization of TRAIL-induced apoptosis Cancer Research
06/04/2012
Abstract 4884: The oncogenic phosphatase PPM1D confers cisplatin resistance in ovarian carcinoma cells by attenuating checkpoint kinase 1 and p53 activation Cancer Research
06/04/2012
Abstract 4883: YM155 potentiates chemosensitivity to gemcitabine in human pancreatic cancer cell line, MiaPaCa-2 Cancer Research
06/04/2012
Abstract 4881: Induction of Bim by the BRAF inhibitor PLX4720 sensitizes human melanoma cells to the BH3 mimetic ABT-737 Cancer Research
06/04/2012
Abstract 4880: Disruption of STAT3 signaling promotes K-Ras induced lung tumorigenesis Cancer Research
06/04/2012
Abstract 4879: Distinct roles of p53 and p19ARF in MYC-dependent tumor oncogene addiction Cancer Research
06/04/2012
Abstract 4878: The fallopian tube is the origin of high-grade serous ovarian carcinomas in a mouse model Cancer Research
06/04/2012
Abstract 4876: Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib Cancer Research
06/04/2012
Abstract 4875: Human HER2 and PI3K H1047R cooperate to promote mammary tumorigenesis in vivo Cancer Research
06/04/2012
Abstract 4874: Small molecule inhibitor of ezrin inhibits metastasis in a transgenic mouse model of osteosarcoma Cancer Research
06/04/2012
Abstract 4873: Comprehensive analysis of 160 whole-genome sequences reveals striking telomere alteration patterns in 9 pediatric cancers Cancer Research
06/04/2012
Abstract 4872: ICGC PedBrain Tumor - Next-generation sequencing identifies novel subgroup-specific mutations and copy number aberrations in medulloblastoma Cancer Research
06/04/2012
Abstract 4870: Integrated genomic analysis of hypodiploid acute lymphoblastic leukemia Cancer Research
06/04/2012
Abstract 4869: Whole genome sequence analysis of MLL rearranged infant acute lymphoblastic leukemias reveals remarkably few somatic mutations: A Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project Cancer Research
06/04/2012
Abstract 4868: Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations within a wide spectrum of genetic heterogeneity Cancer Research
06/04/2012
Abstract 4867: Identification of an inv(16)-encoded CBFA2T3-GLIS2 fusion protein in 34% of non-infant acute megkaryoblastic leukemias: A report from the Pediatric Cancer Genome Project Cancer Research
06/04/2012
Abstract 4866: The atypical kinase SgK223 is a novel mediator of cell invasion in pancreatic cancer Cancer Research
06/04/2012
Abstract 4864: Targeting MET and ERBB2 signaling in aggressive breast cancers Cancer Research
06/04/2012
Abstract 4863: Ubiquitination of the breast cancer oncogene IKK{alpha} is essential for transformation Cancer Research
06/04/2012
Abstract 4862: Autocrine secreted IL-6 and IL-8 play critical and non-redundant roles in basal-like breast cancer cell transformation and growth in vitro and in vivo Cancer Research
06/04/2012
Abstract 4861: Triple-negative breast cancers establish a systemic environment that drives malignant progression of otherwise indolent disseminated tumors via EGF and IGF Cancer Research
06/04/2012
Abstract 4860: Exon capture analysis of G-protein coupled receptors reveals activating mutations in GRM3 in melanoma Cancer Research
06/04/2012
Abstract 4859: Ultra-sensitive detection of rare mutants by droplet digital PCR with conventional TaqMan assays Cancer Research
06/04/2012
Abstract 4857: Allelic-specific imbalance mapping identifies HDAC9 as a candidate susceptibility gene for cutaneous squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4856: Using embryonic melanoblast transcriptome analysis to identify novel mechanisms promoting metastatic melanoma Cancer Research
06/04/2012
Abstract 4855: KLLN, which shares a bidirectional promoter with PTEN, is an AR-regulated tumor suppressor, and induces p53-dependent and -independent apoptosis in breast cancer Cancer Research
06/04/2012
Abstract 4854: Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion positive and fusion negative prostate cancer Cancer Research
06/04/2012
Abstract 4853: Constitutively decreased TGF-{beta} signaling and risk for colorectal cancer Cancer Research
06/04/2012
Abstract 4852: cFLIP-regulated and caspase-8-mediated limited cleavage of RIP1 promotes NF-kB activation and inhibits cell death induced by TRAIL Cancer Research
06/04/2012
Abstract 4851: Selective small molecule inhibition of anti-apoptotic MCL-1 Cancer Research
06/04/2012
Abstract 4850: Sensitization to chemotherapy through interference with FOXO4 - a pivotal node between senescence and apoptosis Cancer Research
06/04/2012
Abstract 4848: A synthetic-lethal screen identifies novel Mcl1 regulators in neuroblastoma Cancer Research
06/04/2012
Abstract 4847: CD95/Fas protects cancer cells from cell death Cancer Research
06/04/2012
Abstract 4846: Manipulation of autophagy during tumor cell killing regulates the growth of neighboring tumor cells Cancer Research
06/04/2012
Abstract 4845: Reeducate the tumor microenvironment to improve the anticancer efficacy of adoptive T-cell therapy Cancer Research
06/04/2012
Abstract 4844: A novel mechanism of immune escape in cancer and its regulation by nitric oxide Cancer Research
06/04/2012
Abstract 4842: p300 targeting impairs treg function and promotes host anti-tumor immunity Cancer Research
06/04/2012
Abstract 4841: Lysis of cancer cells by highly purified T regulatory cells engaged via an EpCAM/CD3-bispecific BiTE antibody Cancer Research
06/04/2012
Abstract 4840: Blockade of IL-10 production in effector B cells significantly increases their therapeutic efficacy in cancer adoptive immunotherapy Cancer Research
06/04/2012
Abstract 4839: Adoptive cell transfer of transgenic T cells elicited a two-wave antitumor cellular immune response consisted of engineered and endogenous T lymphocytes with different sets of functions Cancer Research
06/04/2012
Abstract 4838: Upregulation of ERBB3/HER3 by FOXD3, an adaptive response promoting resistance to RAF/MEK-inhibitors Cancer Research
06/04/2012
Abstract 4837: Tumor microenvironment contributes to RAF-inhibitor resistance through HGF secretion Cancer Research
06/04/2012
Abstract 4836: Inhibition of PI3K/mTOR leads to adaptive resistance in extracellular matrix attached cancer cells Cancer Research
06/04/2012
Abstract 4835: Genetic determinants of mTOR inhibitor response in breast and endometrial cancer Cancer Research
06/04/2012
Abstract 4834: Basement membrane localized tumor cells are protected from HER2-targeted therapy in vivo Cancer Research
06/04/2012
Abstract 4833: Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutics antibody cetuximab Cancer Research
06/04/2012
Abstract 4832: Novel EGFR mutations that cause drug resistance to irreversible pyrimidine but not quinazoline based EGFR inhibitors Cancer Research
06/04/2012
Abstract 4831: Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain Cancer Research
06/04/2012
Abstract 4830: Target-molecular specific near infrared cancer photoimmunotherapy: Detection, treatment, and monitoring of tumors with a theranostic fluorescent probe Cancer Research
06/04/2012
Abstract 4829: A purine scaffold Hsp90 inhibitor has antitumor activity in KSHV-associated malignancies by suppressing vFLIP Cancer Research
06/04/2012
Abstract 4828: A novel small molecule p53-pathway restoring compound suppresses colorectal cancer cells via p73 Cancer Research
06/04/2012
Abstract 4827: Humanized hepsin neutralizing antibody RO5486055 inhibits tumor growth and leads to accumulation of hepsin substrate laminin-332 Cancer Research
06/04/2012
Abstract 4826: A therapeutic sphingosine 1-phosphate antibody improves intratumoral oxygenation and sensitizes to chemotherapy in prostate cancer animal model Cancer Research
06/04/2012
Abstract 4825: Inhibition of AKT abrogates resistance to endocrine therapy in estrogen receptor positive breast cancer Cancer Research
06/04/2012
Abstract 4823: Copy number gain and increased expression of BLM and FANCI is associated with sensitivity to genotoxic chemotherapy in triple negative breast and serous ovarian cancer Cancer Research
06/04/2012
Abstract 4822: Identifiying the anti-Tr antigen in paraneoplastic cerebellar degeneration Cancer Research
06/04/2012
Abstract 4821: Biomarker evaluation In phase I clinical trials of selective PI3K and PI3K/mTOR inhibitors Cancer Research
06/04/2012
Abstract 4820: Identification of a metagene representing SRC activation which is predictive of response to Dasatinib Cancer Research
06/04/2012
Abstract 4819: Gene-expression profiles predict sorafenib efficacy in wild-type EGFR non-small cell lung cancer (NSCLC) Cancer Research
06/04/2012
Abstract 4818: The predictive value of a 5-gene signature as a patient pre-selection tool in medulloblastoma for Hedgehog pathway inhibitor therapy Cancer Research
06/04/2012
Abstract 4817: Using the Mendelian randomization approach to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps Cancer Research
06/04/2012
Abstract 4816: Tobacco smoke modulates estrogen metabolism in the mouse lung Cancer Research
06/04/2012
Abstract 4815: Cytomegalovirus enhances glioblastoma via PDGF-B/STAT3 pathway activation Cancer Research
06/04/2012
Abstract 4814: Hepatocarcinogenesis induced by transgenic expression of hepatitis B virus in mice Cancer Research
06/04/2012
Abstract 4813: EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors Cancer Research
06/04/2012
Abstract 4812: p53 acts during total-body irradiation to promote lymphomagenesis Cancer Research
06/04/2012
Abstract 4811: Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis in telomerase-proficient mice Cancer Research
06/04/2012
Abstract 4810: Multiplexed immunoprecipitation-liquid chromatography-multiple reaction monitoring mass spectrometry quantification of protein expression and phosphorylation for breast cancer biomarkers Cancer Research
06/04/2012
Abstract 4809: Elucidating acquired drug resistance in multiple myeloma using expression proteomics and phosphorylation profiling Cancer Research
06/04/2012
Abstract 4808: Discovery of a phospho-signature predicting response to dasatinib in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4807: Identification of pre-invasive pancreatic cancer serum biomarkers using genetically engineered mouse models and mass spectrometry techniques Cancer Research
06/04/2012
Abstract 4806: Association of changes in 4-aminobutyrate aminotransferase (ABAT) and beta-alanine metabolism with breast cancer and the more aggressive estrogen receptor negative subtype Cancer Research
06/04/2012
Abstract 4805: Distinctive phospho-proteome signatures in non-small cell lung carcinoma tumors Cancer Research
06/04/2012
Abstract 4804: Glycoproteomic analysis of lung cancer malignant pleural effusions identify glycosylated proteins being produced by metastatic tumor cells Cancer Research
06/04/2012
Abstract 4803: Quantitative proteome profiling of CD4+CD25+CCR4+ T-cells to identify potential therapeutic targets for adult T-cell leukemia (ATL) and Human T-lymphotropic virus type-1 associated myelopathy (HAM) Cancer Research
06/04/2012
Abstract 4802: Metabolic distinctions in high grade epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 4801: p90/CIP2A may play a role in regulating the phosphorylation of CREB1 in cancer Cancer Research
06/04/2012
Abstract 4800: Quantitative detection of discriminatory proteins in tissue and serum of ovarian cancer patients by LC-MSE Cancer Research
06/04/2012
Abstract 4799: Identification of drug resistance targets in ovarian cancer using a proteomic approach Cancer Research
06/04/2012
Abstract 4798: Pilot study of plasma biomarker candidates for pancreatic cancer detection - a targeted proteomics approach Cancer Research
06/04/2012
Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells Cancer Research
06/04/2012
Abstract 4796: Carfilzomib and ONX 0912 reduce the level of STAT3 phosphorylation in human B-cell lymphoma cells in vitro and in vivo Cancer Research
06/04/2012
Abstract 4795: Metabolic biomarkers of hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4794: Kras mutation is associated with elevated myeloblastin activity in human lung adenocarcinoma Cancer Research
06/04/2012
Abstract 4793: A novel laser ablation electrospray ionization mass spectrometry (LAESI-MS) platform for biomarker discovery in cancer cells Cancer Research
06/04/2012
Abstract 4792: Biomarker discovery: Correlation of peripheral and tumoral markers in matched tumor and plasma samples Cancer Research
06/04/2012
Abstract 4791: Development of a high resolution mass spectrometry method for the observation and characterization of unknown adducts in human DNA Cancer Research
06/04/2012
Abstract 4790: Mapping the oncogenic kinome using a kinase activity screening array Cancer Research
06/04/2012
Abstract 4789: Stable isotope labeling with amino acids in cell culture (SILAC)-based quantitative proteomics study of a thyroid hormone-regulated secretome in human hepatoma cells Cancer Research
06/04/2012
Abstract 4788: A focused proteomics technology QUEST-MS identified a novel plasma prostate cancer biomarker polypeptide complementing PSA test Cancer Research
06/04/2012
Abstract 4787: Novel upfront sample enrichment nanotechnology identifies prostate, breast, colon, ovarian, lung, pancreatic, and melanoma cancer specific biomarker candidates Cancer Research
06/04/2012
Abstract 4786: Biomarkers for lung adenocarcinoma in salivary proteome Cancer Research
06/04/2012
Abstract 4784: Rapid mass spectrometric profiling of blood sera detects cancer with high accuracy Cancer Research
06/04/2012
Abstract 4783: Proteomic analysis of acute lymphoblastic leukemia: de novo versus relapse Cancer Research
06/04/2012
Abstract 4782: Two-dimensional gel analysis of protein expression profile in patients with invasive squamous cell carcinoma of the uterine cervix for identification of differentially expressed proteins in relation to response to radiation therapy Cancer Research
06/04/2012
Abstract 4781: Analysis of a new chemopreventative agent SHetA2 and its metabolites in Beagle dog liver and plasma Cancer Research
06/04/2012
Abstract 4780: Discovery of novel checkpoint kinase 1 inhibitors by virtual screening based on multiple crystal structures Cancer Research
06/04/2012
Abstract 4779: K-983, an orally available small molecule inhibitor of FGFR, demonstrated prolonged survival in a mouse orthotopic gastric cancer model Cancer Research
06/04/2012
Abstract 4778: Computer-assisted molecular design use for the discovery and optimization of rationally-designed anticancer natural products. Discovery of olive oil-derived oleocanthal as a c-Met inhibitor and optimization of Veratrum alkaloids as Hedgehog signaling inhibitors Cancer Research
06/04/2012
Abstract 4777: Computational strategies for finding protein targets of flavonoids Cancer Research
06/04/2012
Abstract 4776: From in-silico screening to anti-cancer activity: The discovery of a potent inhibitor targeting the JNK-JIP interaction Cancer Research
06/04/2012
Abstract 4775: Compound S2AMN: A potential non-toxic anti-cancer therapy Cancer Research
06/04/2012
Abstract 4774: LC-MS/MS detection of the dansyl-modified biologically active CDK inhibitor VMY-1-103 using an in vivo model system Cancer Research
06/04/2012
Abstract 4773: Synergistic effects of chitosan and docosahexanoic acid on osteopontin expression and secretion in an ovarian cancer cell line, SKOV-3 Cancer Research
06/04/2012
Abstract 4772: Novel drug discovery approach targeting STAT3 for breast cancer therapy using MLSD and drug repositioning Cancer Research
06/04/2012
Abstract 4771: Improved antitumor efficacy of an acid-sensitive doxorubicin derivative delivered by thermally responsive elastin-like polypeptides Cancer Research
06/04/2012
Abstract 4770: Delivery of doxorubicin to multi-drug resistant murine xenografts via drug-loaded micelles formed from mixtures of amphiphilic triblock copolymers Cancer Research
06/04/2012
Abstract 4935: A quantitative model to study cell-type-specific transcriptional regulation between MCF-7 and LNCaP Cancer Research
06/04/2012
Abstract 4934: Employing the Berg Interrogative Biology(R) systems platform to elucidate cellular signaling changes that contribute to the pathophysiology of hepatocellular carcinoma (HCC) Cancer Research
06/04/2012
Abstract 4933: Novel insight into hallmark switch in cancer metabolism using the Interrogative Biology&trade; discovery platform Cancer Research
06/04/2012
Abstract 4932: Exploration of EMT-related microRNAs using function-based screening with expression analysis of E-cadherin in Panc1 line Cancer Research
06/04/2012
Abstract 4931: Biomarker discovery in a large panel of cell lines shows different sample size requirement for prediction of response across a set of compounds Cancer Research
06/04/2012
Abstract 4930: Integrative analysis of genome-wide methylation and expression profiles for metastatic colorectal cancer Cancer Research
06/04/2012
Abstract 4928: Deregulation of asymmetry genes in oligodendrogliomas and glioblastomas Cancer Research
06/04/2012
Abstract 4927: Translational genomics analyses of cholangiocarcinoma identify patients who may respond to tyrosine kinase inhibitors Cancer Research
06/04/2012
Abstract 4926: Modeling the transcriptome landscape of HER2+ breast cancer Cancer Research
06/04/2012
Abstract 4925: The natural enzyme sequestration in signaling cascades provides inherent opportunities for off-target effects induced by kinase inhibitors Cancer Research
06/04/2012
Abstract 4924: Dysregulated transcriptional mechanisms that control crypt cell maturation: A mechanism that contributes to stem cell overpopulation during colon cancer development Cancer Research
06/04/2012
Abstract 4923: Understanding cancer invasion by the systems biological analysis of collective cell migration in 3D tissue models Cancer Research
06/04/2012
Abstract 4922: Patterns of tumor evolution in high grade serous ovarian carcinoma Cancer Research
06/04/2012
Abstract 4921: A new method for identifying a data-consistent self-reconfigurable predictive bio-network model of the cell cycle based on time series data and its application in cancer systems biology Cancer Research
06/04/2012
Abstract 4920: Gene network models identify targets for mammary tumor normalization Cancer Research
06/04/2012
Abstract 4919: Pathway profiling of head and neck cancer cell lines Cancer Research
06/04/2012
Abstract 4918: Modeling polymersome delivery of anticancer therapeutics Cancer Research
06/04/2012
Abstract 4917: Aligning xenograft models to glioblastoma (GB) patient tumors to assess chemovulnerability of patients Cancer Research
06/04/2012
Abstract 4915: Characterization of the EGFR interactome reveals cellular dynamics of receptor signalling and internalisation Cancer Research
06/04/2012
Abstract 4914: Integrated molecular profiles of primary breast tumors reveal differential interleukin signaling and improved prognostic power Cancer Research
06/04/2012
Abstract 4568: Estrogen receptor and progesterone receptor immunocytochemistry staining in circulating tumor cells as compared to primary tumor or metastatic biopsy Cancer Research
06/04/2012
Abstract 4567: Multiplex assay in FFPE tissues to simultaneously quantify the human EGF receptor (HER1-4) family proteins Cancer Research
06/04/2012
Abstract 4566: Dynamic biochemical tissue analysis: A novel in situ assay that demonstrates potential as a diagnostic/prognostic for cancer Cancer Research
06/04/2012
Abstract 4565: Prediction of prognosis by the combination of mutation and methylation in colorectal cancer Cancer Research
06/04/2012
Abstract 4564: Dysregulated p15 in urothelial carcinoma of the upper urinary tract Cancer Research
06/04/2012
Abstract 4563: Monotherapy with a tumor-targeting mutant of Salmonella typhimurium inhibits human glioma in an orthotopic model in nude mice Cancer Research
06/04/2012
Abstract 4562: Comprehensive analysis of the TMPRSS2-ERG translocation during prostate cancer progression Cancer Research
06/04/2012
Abstract 4561: The MMRF CoMMpassSM Study: A prospective, longitudinal, multicenter observational study in newly diagnosed multiple myeloma patients to assess the relationship between patient outcomes, treatment regimens and molecular profiles Cancer Research
06/04/2012
Abstract 4560: A new IGF-1-integrated Child-Pugh score to risk-stratify patients with hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4559: A novel rotational Raman imaging device for early cancer detection Cancer Research
06/04/2012
Abstract 4558: FDG-PET uptake in breast cancer molecular subtypes Cancer Research
06/04/2012
Abstract 4557: Development of a melanocortin receptor 1 targeted probe for molecular imaging of melanoma Cancer Research
06/04/2012
Abstract 4556: Epidermal growth factor signaling alterations in uterine papillary serous carcinoma (UPSC) associate with survival Cancer Research
06/04/2012
Abstract 4555: Protein and glycan biomarkers of malignant potential in pancreatic cyst fluid Cancer Research
06/04/2012
Abstract 4554: QPCR and sequence analysis of DNA template from a microfluidic CTC isolation platform Cancer Research
06/04/2012
Abstract 4553: Multiplexed, digital gene expression and fusion transcript analysis to screen for EML4-ALK positive lung cancer Cancer Research
06/04/2012
Abstract 4552: Utilization of pathway activation and somatic mutation analysis in combination in fine needle aspirates to identify candidate drugs for effective treatment of breast cancer Cancer Research
06/04/2012
Abstract 4551: Prognostic impact of GLUT-1 and Ki-67 expressions in early-stage lung adenocarcinomas Cancer Research
06/04/2012
Abstract 4550: NT5E promoter methylation is a favorable breast cancer epigenetic biomarker Cancer Research
06/04/2012
Abstract 4549: SNP array-based molecular analysis predicts response to neoadjuvant chemotherapy in triple negative and HER2-positive breast cancers Cancer Research
06/04/2012
Abstract 4547: Clinical relevance of circulating tumor cells in esophageal cancer Cancer Research
06/04/2012
Abstract 4546: Variability analysis of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) of hepatocellular carcinoma (HCC) Cancer Research
06/04/2012
Abstract 4545: Positron emission tomography (PET) of TSPO expression in preclinical models of human cancer Cancer Research
06/04/2012
Abstract 4544: On using textural information from longitudinal PET scans for predicting tumor response Cancer Research
06/04/2012
Abstract 4543: Uptake of 18F-FDOPA analogue 3H-L-DOPA is mediated by large neutral amino acid transporter LAT1 in human glioblastoma Cancer Research
06/04/2012
Abstract 4542: Early detection of clinically significant prostate cancer at diagnosis: A prospective study using a novel panel of TMPRSS2:ETS fusion gene markers Cancer Research
06/04/2012
Abstract 4541: Metabolomic diagnosis of prostate cancer from urine Cancer Research
06/04/2012
Abstract 4540: Pyruvate kinase M2 (PKM2) associated with poor prognosis in gastric signet ring cell carcinoma Cancer Research
06/04/2012
Abstract 4538: Semiquantitative detection of aberrant methylation as a tumor biomarker in the serum and plasma of patients with gastric cancer Cancer Research
06/04/2012
Abstract 4537: Tumoral expression on peroxisome proliferator-activated receptor <= is an independent prognostic marker in intestinal type of gastric cancer Cancer Research
06/04/2012
Abstract 4536: Identification of new prognostic biomarker of gastric cancer by systems analysis Cancer Research
06/04/2012
Abstract 4535: CENP-E and c-Myc expression identifies a sensitive population of gastric cancer Cancer Research
06/04/2012
Abstract 4534: Large-scale DNA copy number analysis as a biomarker study in the ACTS-CC trial (TRICC0706), a phase III trial of adjuvant chemotherapy with S-1 and UFT/LV in stage III colon cancer in Japan Cancer Research
06/04/2012
Abstract 4533: Characteristics of HS6ST2 expression in colorectal cancer Cancer Research
06/04/2012
Abstract 4532: Peripheral blood lymphocyte subsets can predict the pathological response of rectal cancer patients to chemoradiation Cancer Research
06/04/2012
Abstract 4531: Fucosylated haptoglobin is a novel type of cancer biomarker linked to the prognosis after an operation in colorectal cancer Cancer Research
06/04/2012
Abstract 4529: Prognostic implications of TSPO in human colorectal cancer Cancer Research
06/04/2012
Abstract 4528: Adiponectin receptor 2 is negatively associated with lymph node metastasis of colorectal cancer Cancer Research
06/04/2012
Abstract 4527: The HER3-EREG axis and its role in colorectal cancer aggression Cancer Research
06/04/2012
Abstract 4526: Lumican and Versican predict good outcome in stage II and III colon cancer Cancer Research
06/04/2012
Abstract 4525: p21 as a predictive marker of pathologic complete response after 5-FU based chemoradiotherapy for patients with rectal cancer Cancer Research
06/04/2012
Abstract 4524: Characterization of 28 patient derived colorectal cancer xenografts and analysis for response markers to an antiangiogenic treatment Cancer Research
06/04/2012
Abstract 4523: Stool proteomics reveals new candidate biomarkers for colorectal cancer screening Cancer Research
06/04/2012
Abstract 4522: Androgen receptor is a main driver of aggressiveness in colorectal cancer through the class III {beta}-tubulin pathway Cancer Research
06/04/2012
Abstract 4521: Differential whole genome methylation profile in a responder and a non-responder to chemotherapy in colorectal cancer patients Cancer Research
06/04/2012
Abstract 4520: Elevated serum antibodies against insulin-like growth factor-binding protein-2 allow detecting early stage cancers: Evidences from glioma and colorectal carcinoma studies Cancer Research
06/04/2012
Abstract 4519: A non-invasive test for right-sided colonic neoplasia in diabetics at increased risk, independent of drug therapy and demographics Cancer Research
06/04/2012
Abstract 4517: Syndecan-2 methylation is an early detection biomarker for colorectal cancer with high sensitivity and specificity in small serum sample volumes Cancer Research
06/04/2012
Abstract 4516: Gene expression analysis as a biomarker study for ACTS-CC trial (TRICC0706), a phase III trial for adjuvant chemotherapy of S-1 and UFT/LV against stage III colon cancer in Japan Cancer Research
06/04/2012
Abstract 4515: Low serum levels of a novel anti-inflammatory fatty acid as a new risk factor for colorectal cancer Cancer Research
06/04/2012
Abstract 4514: A comparison of two methodologies to quantify Thymidylate synthase for predicting survival in patients with colorectal cancer treated on CALGB 89803 Cancer Research
06/04/2012
Abstract 4513: KRAS mutation analysis using blood derived cell free tumor DNA for treatment monitoring of metastatic colorectal cancer patients Cancer Research
06/04/2012
Abstract 4512: AT rich interactive domain 3A (ARID3A) overexpression correlates with good prognosis in colorectal cancer Cancer Research
06/04/2012
Abstract 4511A: KMO as a novel diagnostic and prognostic biomarker in canine mammary gland tumors Cancer Research
06/04/2012
Abstract 4511: The effect of obesity-related adipokines at diagnosis on breast cancer survival Cancer Research
06/04/2012
Abstract 4510: BRAF V600E mutation status and survival after colorectal cancer diagnosis according to patient and tumor characteristics Cancer Research
06/04/2012
Abstract 4509: Mitochondrial DNA copy number is inversely associated with overall survival in non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4508: Oxidative protein modifications in serous epithelia ovarian cancer tissues Cancer Research
06/04/2012
Abstract 4507: Deletion of 9p21.3/p16/CDKN2A is associated with poorer survival in primary central nervous system (PCNSL) lymphoma independent of 6q22 effect. A study facilitated by the Surveillance, Epidemiology and End Results Tissue Repository Program (SEER TRP) Cancer Research
06/04/2012
Abstract 4506: TNFRSF10B polymorphisms and haplotypes predicts survival in non-small cell lung cancer patients Cancer Research
06/04/2012
Abstract 4504: Retrospective study of clinicopathologic factors associated with ALK rearrangement and survival outcome in Chinese patients with NSCLC Cancer Research
06/04/2012
Abstract 4503: Cycloxygenase-2 and breast cancer prognosis: The role of gene polymorphisms in the regulation of COX-2 expression and their association with histopathological features Cancer Research
06/04/2012
Abstract 4502: DNA ploidy in tumor correlates with age, and explains some of the poor prognostic impact of age in endometrial carcinomas Cancer Research
06/04/2012
Abstract 4501: Energetic risk and prostate cancer-specific and all-cause mortality in two large cohorts of men with localized prostate cancer Cancer Research
06/04/2012
Abstract 4500: Clinical significance of survivin expression in urothelial carcinoma of the bladder Cancer Research
06/04/2012
Abstract 4499: Loss of ATM (distal chromosome 11q) as a prognostic marker in HPV-negative head and neck squamous cell carcinomas Cancer Research
06/04/2012
Abstract 4498: Prognostic significance of nuclear factor kappa B expression in human papillomavirus-associated oropharyngeal cancer Cancer Research
06/04/2012
Abstract 4497: Biomarkers of HPV in head and neck squamous cell carcinoma Cancer Research
06/04/2012
Abstract 4496: UBCH10 overexpression in human colorectal cancers Cancer Research
06/04/2012
Abstract 4495: Clinical implications of family history of prostate cancer in an active surveillance cohort Cancer Research
06/04/2012
Abstract 4494: Preoperative serum levels of matrix metalloproteinase-2 (MMP-2) and survival of breast cancer among Korean women Cancer Research
06/04/2012
Abstract 4493: Serum X-linked inhibitor of apoptosis protein (XIAP) predictive recurrence of renal cell carcinoma Cancer Research
06/04/2012
Abstract 4492: Colorectal cancer survival by molecular subtypes in a population-based cohort of older women Cancer Research
06/04/2012
Abstract 4491: Transforming growth factor (TGF) <= pathway and clinical outcome of pancreatic cancer Cancer Research
06/04/2012
Abstract 4490: Molecular characteristics of diffuse large B-cell lymphoma in HIV-positive and HIV-negative patients Cancer Research
06/04/2012
Abstract 4489: Clinical specimen-based investigatory study of biomarkers for gastric cancer Cancer Research
06/04/2012
Abstract 4488: Inflammation-related biomarkers and risk of epithelial ovarian cancer Cancer Research
06/04/2012
Abstract 4487: Inverse associations between soluble cytokine receptors and colorectal cancer risk Cancer Research
06/04/2012
Abstract 4486: Mitochondrial DNA copy number is associated with colorectal cancer risk Cancer Research
06/04/2012
Abstract 4485: Prediction of esophageal cancer risk through quantification of gamma-H2AX levels in peripheral blood lymphocytes Cancer Research
06/04/2012
Abstract 4484: A novel objective, image-based phenotypic assay reveals higher {alpha}-radiation-induced {gamma}-H2AX level in peripheral blood lymphocytes as a risk predictor for lung cancer Cancer Research
06/04/2012
Abstract 4483: Early life exposures and promoter methylation in breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study Cancer Research
06/04/2012
Abstract 4482: Effects of lifestyle modification on global DNA methylation in minority breast cancer survivors Cancer Research
06/04/2012
Abstract 4481: Vitamin D pathway gene variants associated with vitamin D deficiency in African Americans Cancer Research
06/04/2012
Abstract 4480: Associations between phytanic acid and alpha-methylacyl-CoA racemase (AMACR) expression in the normal human prostate Cancer Research
06/04/2012
Abstract 4479: Polymorphisms in the nucleotide excision repair genes, ERCC1 and ERCC2/XPD and carcinogen DNA adducts in human lung Cancer Research
06/04/2012
Abstract 4478: Erythrocyte magnesium, TRPM7 Thr1482Ile polymorphism, and colorectal adenoma risk Cancer Research
06/04/2012
Abstract 4477: Progesterone (P4) and testosterone (T) concentrations in random fine needle aspirates of the breast in pre- and postmenopausal women Cancer Research
06/04/2012
Abstract 4476: Molecular typing of breast cancer cases among a Hispanic population and its association with body mass index Cancer Research
06/04/2012
Abstract 4475: Association of endometrial cancer risk factors and DNA methylation in benign endometrial tissue Cancer Research
06/04/2012
Abstract 4474: Occupational exposure to benzene and leukocyte telomere length Cancer Research
06/04/2012
Abstract 4473: Urinary biomarkers of exposure to 1,3-Butadiene and its bioactivation to DNA-reactive metabolites Cancer Research
06/04/2012
Abstract 4472: Circulating thyroxine (T4), thyroid-stimulating hormone (TSH), and hypothyroid status and the risk of prostate cancer Cancer Research
06/04/2012
Abstract 4471: Autoantibodies in infertility are associated with ovarian cancer Cancer Research
06/04/2012
Abstract 4470: Pre-diagnostic gonadotropin levels and development of testicular germ cell tumors Cancer Research
06/04/2012
Abstract 4469: S-adenosylmethionine (SAM), S-adenosylhomocysteine (SAH), and colorectal adenoma risk Cancer Research
06/04/2012
Abstract 4468: Pre-diagnostic steroid hormone levels and risk of testicular germ cell tumors Cancer Research
06/04/2012
Abstract 4467: Gene-specific methylation of leukocyte DNA in relation to colorectal cancer among male smokers from a nested case-control study in the ATBC Study Cancer Research
06/04/2012
Abstract 4466: Local regulation of steroid hormones in the breast is related to single nucleotide polymorphism of steroid metabolism genes Cancer Research
06/04/2012
Abstract 4465: Breast cancer risk factor associations with breast tissue morphometry: results from the Komen for the Cure(R) Tissue Bank Cancer Research
06/04/2012
Abstract 4463: Serum phytanic acid and prostate cancer risk: Results from a nested case-control study Cancer Research
06/04/2012
Abstract 4462: Relative telomere length in circulating serum DNA as a novel non-invasive biomarker in hepatocarcinogenesis Cancer Research
06/04/2012
Abstract 4461: A prospective study of blood mitochondrial DNA copy number and risk of renal cell carcinoma Cancer Research
06/04/2012
Abstract 4460A: Meat-related compounds and colorectal cancer risk by anatomical subsite Cancer Research
06/04/2012
Abstract 4460: Breast cancer knowledge and awareness among high school and college students in mid-Western USA Cancer Research
06/04/2012
Abstract 4459: Evaluation of the performance of a previous day recall of time spent in active and sedentary behaviors Cancer Research
06/04/2012
Abstract 4458: The burden of cancer in Japan Cancer Research
06/04/2012
Abstract 4457: Knowledge and acceptability of the HPV vaccine among high-risk men attending an STD clinic in Puerto Rico Cancer Research
06/04/2012
Abstract 5757: A new functional classification of lung and breast cancers based on siRNA mediated knockdown of 48 NRs and 72 CoRegulators Cancer Research
06/04/2012
Abstract 5756: Protein biomarkers for breast cancer risk are specifically correlated with local steroid hormones in nipple aspirate fluid Cancer Research
06/04/2012
Abstract 5755: PR/AMPK-IGF/PI3K network plays a major role on progestin-resistance in endometrial cancer therapy Cancer Research
06/04/2012
Abstract 5754: Temozolomide therapy for progressive metastatic paraganglioma/pheochromocytoma: SDHB mutation as a prognosis biomarker for efficacy Cancer Research
06/04/2012
Abstract 5753: Potential therapeutic use of ER beta modulators in treating endocrine therapy resistant breast cancers Cancer Research
06/04/2012
Abstract 5752: Expression and biological significance of adiponectin receptors in papillary thyroid carcinoma Cancer Research
06/04/2012
Abstract 5751: Detection of HMTV in breast and endometrium carcinomas Cancer Research
06/04/2012
Abstract 5750: Synergistic effects of everolimus and bicalutamide in castration-resistant prostate cancer: Results from a phase I/II clinical trial Cancer Research
06/04/2012
Abstract 5748: Elevated aromatase, estrogen receptor variants and human hepatocellular carcinoma: a unifying hypothetical model Cancer Research
06/04/2012
Abstract 5747: Elucidating the mechanisms by which Snail transcription factor promotes resistance to chemotherapy in breast carcinomas Cancer Research
06/04/2012
Abstract 5746: ARC-P HS+: A versatile radiosynthesizer for the production of PET tracers Cancer Research
06/04/2012
Abstract 5745: Synthesis and characterization of a folate receptor alpha-specific ligand for distinguishing cancer tissue from sites of inflammation Cancer Research
06/04/2012
Abstract 5744: Preclincial therapy of androgen independent prostate cancer using combinationLu-177-BB2r targeting peptides and docetaxel Cancer Research
06/04/2012
Abstract 5743: Positron emission tomography (PET) imaging analogs of glutamine: Development and evaluation as probes for cancer imaging Cancer Research
06/04/2012
Abstract 5742: Up-regulation of mitochondrial chaperone TRAP1 in cancer precursors associated with chronic inflammation Cancer Research
06/04/2012
Abstract 5741: GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity Cancer Research
06/04/2012
Abstract 5740: 124I-CLR1404 and 131I-CLR1404: Broad spectrum diapeutic agents for cancer cell-targeted PET imaging and molecular radiotherapy Cancer Research
06/04/2012
Abstract 5739: Characterization of the metabolism and DNA adduct formation of 2-amino-9H-pyrido[2,3-b]indole in human hepatocytes Cancer Research
06/04/2012
Abstract 5738: Expression profiling of microRNA and mRNA on hepatic inflammation in high-fat induced murine model Cancer Research
06/04/2012
Abstract 5737: Development of targeted imaging agents for Cholecystokinin 2 receptor expressing cancers Cancer Research
06/04/2012
Abstract 5735: Synthesis and characterization of PEG-ylated porphyrins for targeting the epidermal growth factor receptor in colorectal cancer detection Cancer Research
06/04/2012
Abstract 5734: Role of the inflammasome complex in Cr(VI)-induced lung injury and inflammation Cancer Research
06/04/2012
Abstract 5733: Detection of M1dG and 6-oxo-M1dG from biological samples in rats Cancer Research
06/04/2012
Abstract 5732: Mercapturic acid excretion and N7-GA-Gua DNA adduct formation after low dose oral application of acrylamide to rats Cancer Research
06/04/2012
Abstract 5731: PET and fluorescence imaging of brain cancer with a dual modality probe based on sarcophagine cage Cancer Research
06/04/2012
Abstract 5730: Dosimetric properties of a new thermobrachytherapy seed with ferromagnetic core for treatment of solid tumors Cancer Research
06/04/2012
Abstract 5729: The Wnt transcription factor TCF4 mediates resistance of colorectal cancer cells to (chemo-) radiotherapy in a {beta}-catenin-independent manner Cancer Research
06/04/2012
Abstract 5727: Competitive inhibition of mTOR results in tumor specific radiosensitization Cancer Research
06/04/2012
Abstract 5726: Human epidermal growth factor 3 (HER3) blockade with U3-1287/AMG888 modulates radiosensitivity in the lung and head and neck carcinomas Cancer Research
06/04/2012
Abstract 5725: Accuracy of off-line bioluminescence imaging to localize targets in pre-clinical radiation research Cancer Research
06/04/2012
Abstract 5724: HER2-mediated resistance of breast cancer stem cells in HER2-negative/low breast cancer Cancer Research
06/04/2012
Abstract 5723: Inhibition of angiogenesis in the mouse heart by ionizing radiation Cancer Research
06/04/2012
Abstract 4627: Generation and characterization of non-competitive furin-inhibiting nanobodies Cancer Research
06/04/2012
Abstract 4626: Application of IgDARTs&trade; designed for the simultaneous targeting of EGFR and IGF1R exhibit potent anti-tumor activity Cancer Research
06/04/2012
Abstract 4625: IMGN529, a CD37-directed antibody-drug conjugate for the treatment of B-cell malignancies, has a favorable in vitro safety profile Cancer Research
06/04/2012
Abstract 4623: Human anti-nucleolin antibodies with broad spectrum anticancer activity Cancer Research
06/04/2012
Abstract 4621: EMP2 regulates the tumor microenvironment and is a novel therapeutic target for triple negative breast cancer Cancer Research
06/04/2012
Abstract 4620: A YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: A potential therapeutic agent in cancers Cancer Research
06/04/2012
Abstract 4619: PF-04449913 reverts multi drug resistance (MDR) by a strong down-regulation of ABCA2 and BCL2 on leukemia stem cells in phase I acute myeloid leukemia and chronic myeloid leukemia treated patients Cancer Research
06/04/2012
Abstract 4618: Response post first autologous stem cell transplantation (ASCT) for multiple myeloma identify patients who may benefit from tandem transplants: A single center prospective phase II study Cancer Research
06/04/2012
Abstract 4617: Hu177 cryptic epitope: A novel biomarker for the monitoring of treatment of ovarian cancer Cancer Research
06/04/2012
Abstract 4616: Age dependent increase in Prostaglandin pathway coincides with onset of ovarian cancer in laying hens Cancer Research
06/04/2012
Abstract 4615: Key miRNAs and co-targets in patients of OPSC and OCC Cancer Research
06/04/2012
Abstract 4614: Karyometry in atypical endometrial hyperplasia: A Gynecologic Oncology Group study Cancer Research
06/04/2012
Abstract 4612: Overexpression of cholesterol metabolism regulatory gene farnesyl diphosphate farnesyltransferase is associated with poor prognosis of non-small cell lung cancer patient and promotes metastasis through feedback regulation of SPP1-PI3K-AKT signaling pathway Cancer Research
06/04/2012
Abstract 4610: Characterizing TGF{beta}1-inducible EMT models in NSCLC helps define critical EMT-associated genes for therapeutic targeting Cancer Research
06/04/2012
Abstract 4609: Epigenetic regulation of BRM Cancer Research
06/04/2012
Abstract 4608: RRBP1 overexpression is frequently found In lung cancer patients and alleviates intracellular stress induced apoptosis through positive regulation of GRP78 in lung cancer Cancer Research
06/04/2012
Abstract 4607: A translational study of Tumor Treating Fields in non small cell lung cancer Cancer Research
06/04/2012
Abstract 4606: Randomized phase 2 study of efatutazone in combination with carboplatin and paclitaxel as first-line therapy for metastatic non-small cell lung cancer (NSCLC) Cancer Research
06/04/2012
Abstract 4605: Neurotrophin system expression in human lung cancer stem cells Cancer Research
06/04/2012
Abstract 4604: Some of oral squamous cell carcinomas might originate from minor salivary glands, and these tumors shows aggressive biological behavior and poor prognosis Cancer Research
06/04/2012
Abstract 4603: Optically-guided surgical approach using fluorescence visualization can significantly improve locoregional recurrence and overall survival for early stage oral cancer Cancer Research
06/04/2012
Abstract 4602: Preclinical evaluation of the AKT inhibitor MK2206 in nasopharyngeal carcinoma cell lines Cancer Research
06/04/2012
Abstract 4601: The role of nicotine-induced oxidative stress in oral cancer cells Cancer Research
06/04/2012
Abstract 4600: Examining the selective contribution of chromosomal instability to tumor evolution and prognosis Cancer Research
06/04/2012
Abstract 4599: Comprehensive molecular oncogenomic profiling & miRNA analysis of prostate cancer Cancer Research
06/04/2012
Abstract 4598: Allelic loss of NDST4, a putative tumor suppressor gene, is associated with tumor progression of colorectal cancer Cancer Research
06/04/2012
Abstract 4597: Telomere maintenance mechanism and expression in colorectal cancer Cancer Research
06/04/2012
Abstract 4596: Missense mutations in the p53 DNA-binding motifs (DBMs) are associated with shorter time to progression (TTP) in erlotinib-treated, EGFR-mutated patients Cancer Research
06/04/2012
Abstract 4595: Molecular imaging of urothelial cancer using EGFR-binding peptides Cancer Research
06/04/2012
Abstract 4594: Dual PI3K/mTOR blockade by NVP-BEZ235 sensitizes head and neck squamous cell carcinoma to radiotherapy Cancer Research
06/04/2012
Abstract 4593: Expression of Ecdysoneless in breast cancer progression predicts poor outcome in breast cancer patients Cancer Research
06/04/2012
Abstract 4592: Sox8 as a molecular marker of oligodendroglial tumors Cancer Research
06/04/2012
Abstract 4591: Biotinylated derivatives of selective high affinity ligand (SHAL) therapeutics as companion diagnostics for prescreening non-Hodgkin's lymphoma patients Cancer Research
06/04/2012
Abstract 4590: Genome-wide identification of possible methylation markers chemosensitive to targeted regimens in colorectal cancers Cancer Research
06/04/2012
Abstract 4588: Frequency and clinical characteristics of c-MET mutation in malignant melanoma Cancer Research
06/04/2012
Abstract 4586: Use of triple combination array analysis to identify STEAP family member 4 (STEAP4), a novel tumor related gene in hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4585: Expression of fibroblast growth factor-9 is associated with poor prognosis of resected non-small cell lung cancer patients Cancer Research
06/04/2012
Abstract 4584: {beta}-catenin (CTNNB1) and BRAF mutations in advanced hepatocellular carcinoma Cancer Research
06/04/2012
Abstract 4583: Comparison of repeated minor liver resection and major resection on lung metastasis growth in mice Cancer Research
06/04/2012
Abstract 4582: Regulation of Kruppel-Like Factor 4 (KLF4) expressions via Yin Yang 1 (YY1) in B Non-Hodgkin's Lymphomas (B-NHLs): KLF4 upregulation is associated with unfavorable overall survival in pediatric B-NHL Cancer Research
06/04/2012
Abstract 4581: Pim-1 kinase inhibition in the absence of FLT3 inhibition results in cytostatic effects in acute myeloid leukemia cells Cancer Research
06/04/2012
Abstract 4580: Personalized treatment selection for therapy-resistant AML by integrating ex-vivo drug sensitivity and resistance testing (DSRT) as well as serial genomic, transcriptomic and phosphoproteomic profiling Cancer Research
06/04/2012
Abstract 4579: The novel MEK Inhibitor GSK1120212b inhibits HMCL growth in vitro and synergises with a range of conventional and novel anti-myeloma therapies Cancer Research
06/04/2012
Abstract 4578: Identification of a gene expression signature that is associated with dependency on FGFR3 rather than EGFR in bladder cancer cells Cancer Research
06/04/2012
Abstract 4577: Targeting N-glycosylation of tyrosine kinase receptors for preventing tumorigenesis and malignant transformation of neurofibromatosis type I Cancer Research
06/04/2012
Abstract 4575: Three-gene diagnostic classifier for ALK negative ALCL Cancer Research
06/04/2012
Abstract 4574: FGFR1 amplification in high grade, estrogene receptor positive and metastasized breast cancers Cancer Research
06/04/2012
Abstract 4573: Enriched driver genes based on histology and smoking status in Asian patients with non-small cell lung cancer Cancer Research
06/04/2012
Abstract 4572: Frequent MLL3 frameshift mutations in microsatellite-deficient colorectal cancer Cancer Research
06/04/2012
Abstract 4571: An international overview of the "state of the science" of regulatory standards for human tissue biobanking Cancer Research
06/04/2012
Abstract 4570: Functional analysis of gene expression profiling of primary and metastatic melanoma: Possible implications from BRAF mutant and wild-type cell lines Cancer Research
06/04/2012
Abstract 4569: Amplicon-targeted ultra-deep sequencing for the detection of KRAS, BRAF, and PIK3CA actionable mutations Cancer Research