Continuous arterial blood gas monitoring during bilateral sequential lung transplantation.

Journal of cardiothoracic and vascular anesthesia

PubMedID: 10392673

Myles PS, Buckland MR, Weeks AM, Bujor M, Moloney J. Continuous arterial blood gas monitoring during bilateral sequential lung transplantation. J Cardiothorac Vasc Anesth. 1999;13(3):253-7.
OBJECTIVE
To determine the accuracy and clinical utility of a continuous arterial blood gas (ABG) monitor during lung transplantation.

DESIGN
Prospective, observational cohort study.

SETTING
University hospital.

PARTICIPANTS
Eleven patients undergoing bilateral sequential lung transplantation (BSLTx).

INTERVENTIONS
Repeated ABG sampling.

MEASUREMENTS AND MAIN RESULTS
Agreement was measured by the bias (limits of agreement): pH, 0.006 (-0.10 to 0.10); PaO2, -22 mmHg (-130 to 86 mmHg); and PaCO2, -1.6 mmHg (-13.4 to 10.2 mmHg). Sensitivity and specificity of the Paratrend 7 (Biomedical Sensors, Ltd, Malvern, PA) PaO2 measurements (to detect PaO2 < 100 mmHg) were 84.6% and 97.6%, respectively.

CONCLUSION
Continuous ABG monitoring with the Paratrend 7 shows sufficiently good agreement with laboratory blood gas analysis during BSLTx and thus is a convenient alternative to intermittent laboratory blood gas measurement. Because of the potential for significant (and sometimes rapid) acid-base disturbances, continuous ABG monitoring may have a role during most lung transplantation procedures.