Vitamin, Mineral, and Multivitamin Supplements for the Primary Prevention of Cardiovascular Disease and Cancer: U.S. Preventive Services Task Force Recommendation Statement.

Annals of Internal Medicine

PubMedID: 24566474

Moyer VA, U.S. Preventive Services Task Force. Vitamin, Mineral, and Multivitamin Supplements for the Primary Prevention of Cardiovascular Disease and Cancer: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med. 2014;160(8):558-64.
DESCRIPTION
Update of the 2003 U.S. Preventive Services Task Force (USPSTF) recommendation on vitamin supplementation to prevent cardiovascular disease or cancer.

METHODS
The USPSTF reviewed the evidence on the efficacy of the use of multivitamin or mineral supplements in the general adult population for the prevention of cardiovascular disease and cancer.

POPULATION
This recommendation applies to healthy adults without special nutritional needs (typically aged 50 years or older). It does not apply to children, women who are pregnant or may become pregnant, or persons who are chronically ill or hospitalized or have a known nutritional deficiency.

RECOMMENDATION
The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of the use of multivitamins for the prevention of cardiovascular disease or cancer. (I statement)The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of the use of single- or paired-nutrient supplements (except ß-carotene and vitamin E) for the prevention of cardiovascular disease or cancer. (I statement)The USPSTF recommends against the use of ß-carotene or vitamin E supplements for the prevention of cardiovascular disease or cancer. (D recommendation).