Effect of acidic fibroblast growth factor (aFGF) on phagocytosis in mouse peritoneal macrophages.

Microbiology and immunology

PubMedID: 9572047

Ichinose M, Sawada M, Sasaki K, Oomura Y. Effect of acidic fibroblast growth factor (aFGF) on phagocytosis in mouse peritoneal macrophages. Microbiol Immunol. 1998;42(2):139-42.
The effects of acidic fibroblast growth factor (aFGF) on phagocytosis in peritoneal macrophages from thioglycollate-elicited mice were examined using flow cytometry. aFGF enhanced phagocytosis of fluorescein isothiocyanate-labeled latex particles in a dose-dependent manner. Basic fibroblast growth factor (bFGF) also enhanced phagocytosis. This study suggests that aFGF can modulate an important activity of macrophages.