An efficient synthesis of 1a,25-dihydroxy-20-epi-vitamin D3.

The Journal of steroid biochemistry and molecular biology

PubMedID: 23396126

Fraga R, López-Pérez B, Sokolowska K, Guini A, Regueira T, Díaz S, Mouriño A, Maestro MA. An efficient synthesis of 1a,25-dihydroxy-20-epi-vitamin D3. J Steroid Biochem Mol Biol. 2013;13614-6.
The synthesis of 1a,25-dihydroxy-20-epi-vitamin D3 (1) by Pd(0)-catalyzed coupling between the boronate ester (2) and the enol triflate (3) is described. This article is part of a Special Issue entitled 'Vitamin D Workshop'.