Depression is correlated with the psychological and physical aspects of sexual dysfunction in men.

International journal of impotence research

PubMedID: 23466661

Pastuszak AW, Badhiwala N, Lipshultz LI, Khera M. Depression is correlated with the psychological and physical aspects of sexual dysfunction in men. Int J Impot Res. 2013;.
Few studies have objectively examined the relationship between depression and various stages of sexual function. Here we associate depression and sexual function using validated questionnaires. A retrospective review of 186 men was performed; demographics and serum hormone levels were obtained. Responses to questionnaires evaluating depressive symptoms (Patient Health Questionnaire (PHQ-9)), sexual function (International Index of Erectile Function (IIEF)) and hypogonadal symptoms (quantitative Androgen Decline in the Aging Male (qADAM)) completed by each patient were correlated using Spearman's rank correlation. Mean±s.d. subject age: 52.6±12.7 years; mean serum hormone levels: TT 429.8±239.2?ng?dl(-1), free testosterone 9.72±7.5?pg?ml(-1) and estradiol 34.4±22.8?pg?ml(-1). Negative correlations were observed between total PHQ-9 score and the sexual desire (?=-0.210, P=0.006), intercourse satisfaction (?=-0.293, P<0.0001) and overall satisfaction (?=-0.413, P<0.0001) domains of the IIEF and individual IIEF questions pertaining to erectile function. Men with a PHQ-9 score ?10 (mild depression or worse), had lower sexual desire and sex life satisfaction. A negative correlation between PHQ-9 score and qADAM score (?=-0.634, P<0.0001) was observed and men with higher PHQ-9 score had lower qADAM scores. Depressive symptoms in men correlate with both psychological as well as physical aspects of sexual function.International Journal of Impotence Research advance online publication, 7 March 2013; doi:10.1038/ijir.2013.4.