[Results of treatment with interferon for chronic hepatitis B in children].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

PubMedID: 9523482

Kowalik-Mikolajewska B, Ladyzynska E, Loch T, Wojnarowski M. [Results of treatment with interferon for chronic hepatitis B in children]. Pol Merkur Lekarski. 1997;3(17):241-4.
8 children with chronic hepatitis B were treated with interferon, 3 M.U. subcutaneously three times a week for 4-5 months. Seroconversion from HBe antigen to anti HBe antibodies was observed in 3 of them and in 1 also seroconversion from HBs antigen to anti HBs antibodies. In remaining 5 cases the therapy was ineffective which could be caused by: more advanced inflammatory lesions in liver, infection with HB in infancy and low activity of aminotransferases before the treatment. Side effects of interferon were only transitory and in no case caused cessation of the therapy.