[Albendazole in Japanese juvenile with enterobiasis in whom pyrantel pamoate is not effective].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases

PubMedID: 22117382

Ohnishi K, Kobayashi K, Iwabuchi S, Nakamura-Uchiyama F. [Albendazole in Japanese juvenile with enterobiasis in whom pyrantel pamoate is not effective]. Kansenshogaku Zasshi. 2011;85(5):520-2.
A 18-year-old Japanese woman seen as an outpatient for refractory enterobiasis had been treated with pyrantel pamoate over 40 times since the age of 11. She washed her hands and cleaned house frequently, and all family members took pyrantel pamoate, but Enterobius vermicularis eggs remained. She was orally administered 400 mg of albendazole 3 times in clinic visits, after which eggs have not been seen for 1 year. Pyrantel pamoate is used widely against enterobiasis in Japan. Our case shows albendazole to also be effective against enterobiasis. Albendazole thus appears to be a useful anti-helminthic in enterobiasis patients in whom pyrantel pamoate is not effective. This is, to our knowledge, the first case of enterobiasis treated with albendazole in Japan.