The role of laboratory testing in the evaluation of headache.

The Medical clinics of North America

PubMedID: 23419622

Donohoe CD. The role of laboratory testing in the evaluation of headache. Med Clin North Am. 2013;97(2):217-24.
Blood tests have a minor role in headache management and that role is limited to a few secondary headache conditions. In headache, as with any symptom, laboratory tests should be chosen based on solid clues derived from the targeted history and physical examination. A shotgun approach to blood tests that includes rare diseases or those with low local prevalence frequently yields false-positive results, which exposes the patient to the expense, anxiety, and risk inherent in misdiagnosis. Keep it simple and do not forget about spinal fluid.