Reduced concentration of secretory IgA indicates changes of local immunity in children with adenoid hyperplasia and secretory otitis media.

ORL; journal for oto-rhino-laryngology and its related specialties

PubMedID: 1784473

Hess M, Kugler J, Haake D, Lamprecht J. Reduced concentration of secretory IgA indicates changes of local immunity in children with adenoid hyperplasia and secretory otitis media. ORL J Otorhinolaryngol Relat Spec. 1992;53(6):339-41.
Children with adenoid hyperplasia and secretory otitis media show significantly lower immunoglobulin A (sIgA) concentrations in their saliva compared to matched controls. Salivary albumin and cortisol levels do not differ in both groups. Changes in local immunity, dilution or stress as possible factors for the reduction of sIgA concentrations are discussed.