A genomic sequence of the Schizosaccharomyces pombe 16 kDa vacuolar H(+)-ATPase.

Yeast (Chichester, England)

PubMedID: 1839480

Toyama R, Goldstein DJ, Schlegel R, Dhar R. A genomic sequence of the Schizosaccharomyces pombe 16 kDa vacuolar H(+)-ATPase. Yeast. 1991;7(9):989-91.
We have isolated the gene encoding the 16 kDa vacuolar H(+)-ATPase from Schizosaccharomyces pombe. On the basis of RNA splicing signals and amino acid sequence homology with other 16 kDa H(+)-ATPases, the genomic DNA sequence indicated the 16 kDa protein is encoded by five exons. The C-terminal 50 amino acids has more than 90% homology with vacuolar H(+)-ATPases of mammalian cells.