Low baseline startle in anorexia nervosa patients.

Progress in neuro-psychopharmacology & biological psychiatry

PubMedID: 22954471

Bellodi L, Martoni RM, Galimberti E, Cavallini MC. Low baseline startle in anorexia nervosa patients. Prog Neuropsychopharmacol Biol Psychiatry. 2013;4026-9.
This study examined baseline startle magnitude, using eye blink response and skin conductance response in anorexia nervosa patients. Twenty female in-patients with anorexia nervosa and an equal number of female healthy controls were tested. Baseline startle response was assessed during blank screens while four startling loud sounds (a 116 dB, 1s, 250 Hz tone) were delivered with a time interval ranging from 35 to 55 s. It was investigated if BMI and state anxiety correlated with physiological responses. The clinical sample showed a lower baseline startle reflex measured with both indices, than healthy controls. Across the whole sample, a single regression model partially explained the relationship between BMI and baseline skin conductance response.