Fatal pulmonary complications in an immunodeficient child with chronic active Epstein-Barr virus infection.

Pneumonologia i alergologia polska : organ Polskiego Towarzystwa Ftyzjopneumonologicznego, Polskiego Towarzystwa Alergologicznego, i Instytutu Gruzlicy i Chorob Pluc

PubMedID: 24964240

Szczawinska-Poplonyk A, Jonczyk-Potoczna K, Ossowska L, Breborowicz A. Fatal pulmonary complications in an immunodeficient child with chronic active Epstein-Barr virus infection. Pneumonol Alergol Pol. 2014;82(4):364-367.
Primary Epstein-Barr virus infection in children typically presents as infectious mononucleosis and in immunocompetent individuals severe pneumonitis proves to be a rare complication. Chronic active Epstein-Barr virus infection (CAEBV) is associated with multiple life-threatening conditions, including interstitial lung disease with fibrosis and lymphoid and lymphohistiocytic infiltrations. We report on a pediatric patient in whom CAEBV resulted in severe pneumopathy with a fatal outcome.