Clinical implications of initial peripheral eosinophilia in acute eosinophilic pneumonia.

Respirology (Carlton, Vic.)

PubMedID: 24985714

Jhun BW, Kim SJ, Kim K, Lee JE. Clinical implications of initial peripheral eosinophilia in acute eosinophilic pneumonia. Respirology. 2014;.
BACKGROUND AND OBJECTIVE
The initial peripheral eosinophil count (PEC) is rarely elevated but tends to increase during the clinical course of acute eosinophilic pneumonia (AEP). We evaluated whether initial peripheral eosinophilia is an indicator of mild disease in patients with AEP.

METHODS
We retrospectively examined associations between initial peripheral absolute eosinophil count, inflammatory markers and clinical characteristics in 85 patients with AEP.

RESULTS
Of 85 patients, 24 (28%) had initial peripheral eosinophilia (>500/┬ÁL). Initial peripheral absolute eosinophil count was inversely correlated to white blood cell (WBC) count (??=?-0.386, P?
CONCLUSIONS
Initial PEC may be related to a milder disease status on admission, compared with normal PEC in patients with AEP. This may help to stratify disease severity in AEP.