Risk Factors for Eosinophilic esophagitis.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

PubMedID: 24990069

Philpott H, Gibson P, Nandurkar S, Royce SG, Thien F. Risk Factors for Eosinophilic esophagitis. Clin Exp Allergy. 2014;.
Eosinophilic esophagitis (EoE) is conceptualised as a chronic antigen driven disease, whereby food and/or aeroallergens stimulate an eosinophil-rich infiltrate in the esophagus that produces the clinical syndrome of dysphagia, feeding difficulties (in young children) and food bolus obstruction(1, 2). EoE was first recognised as a distinct clinical entity only recently, in 1993(2). The epidemiology, basic scientific and clinico-pathological data are hence somewhat limited, and to date the most cleary defined risk factors for EoE are gender (male predominance) race (mainly a disease of white Caucasians) and atopy (elevated serum IgE to common aeroallergens and other allergic conditions (asthma, seasonal rhinitis and atopic dermatitis)). This article is protected by copyright. All rights reserved.