Esophageal adenocarcinoma with white opaque substance observed by a magnifying endoscopy with narrow band imaging.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

PubMedID: 25041337

Yoshii S, Kato M, Honma K, Fujinaga T, Tsujii Y, Maekawa A, Inoue T, Hayashi Y, Akasaka T, Shinzaki S, Nishida T, Iijima H, Tsujii M, Morii E, Takehara T. Esophageal adenocarcinoma with white opaque substance observed by a magnifying endoscopy with narrow band imaging. Dig Endosc. 2014;.
White opaque substance (WOS) is observed in the gastric neoplasia of 0-IIa type using a magnifying endoscopy with narrow band imaging (NBI-ME). Colonic and duodenal neoplasms with WOS have also been reported. Immunohistochemical examination with adipophilin reveals WOS in gastric neoplasms represents lipid droplets and WOS is specific for the neoplasm with intestinal or gastrointestinal phenotype. We herein report a case of adenocarcinoma of esophagogastric junction with WOS. A male patient in his sixties was found to have an esophageal elevated lesion by an esophagogastroduodenoscopy (EGD). NBI-ME showed whitish deposits which looked similar to WOS observed in gastric neoplasms. He underwent endoscopic submucosal dissection (ESD) and the lesion was resected in a single piece. This tumor had diffuse positivity for adipophilin and gastrointestinal phenotype.