Restless legs syndrome in patients with systemic sclerosis : Prevalence and possible causes.

Zeitschrift fur Rheumatologie

PubMedID: 23456369

Ostojic P, Jovic T, Stojic B. Restless legs syndrome in patients with systemic sclerosis : Prevalence and possible causes. Z Rheumatol. 2013;72(6):590-593.
This study aims to assess the prevalence and possible causes of restless legs syndrome (RLS) in patients with systemic sclerosis (SSc). The prevalence of RLS was assessed in 27 patients with SSc and 60 healthy controls. We evaluated the impact of age, disease duration, disease form, antibodies, and metoclopramide on the development of RLS in SSc patients. In order to reveal peripheral neuropathy or iron deficiency as possible causes of the syndrome, patients with RLS underwent electromyoneurography (EMNG) and ferritin level testing. RLS was diagnosed in 40.7% of SSc patients (11 out of 27), compared to 4.9% of healthy controls (p