Pd(dba)2 vs Pd2(dba)3: An in-Depth Comparison of Catalytic Reactivity and Mechanism via Mixed-Ligand Promoted C-N and C-S Coupling Reactions.

Organic letters

PubMedID: 25080102

Cong M, Fan Y, Raimundo JM, Tang J, Peng L. Pd(dba)2 vs Pd2(dba)3: An in-Depth Comparison of Catalytic Reactivity and Mechanism via Mixed-Ligand Promoted C-N and C-S Coupling Reactions. Org Lett. 2014;.
With the help of mixed ligand catalytic systems, the analogous mechanisms behind the cognate performance by Pd(dba)2 and Pd2(dba)3 in catalyzing C-N and C-S coupling reactions were demonstrated. This information is instrumental in organic synthesis requiring Pd-catalyzed cross-coupling reactions and may also be valuable to other Pd-catalyzed transformations.