A translocation t(9;11)(p11;q23) in T-cell acute lymphoblastic leukemia (FAB-l2).

Cancer genetics and cytogenetics

PubMedID: 3258175

Fan YS, Rowe JM, Dal Cin PD, SANDBERG AA. A translocation t(9;11)(p11;q23) in T-cell acute lymphoblastic leukemia (FAB-l2). Cancer Genet Cytogenet. 1988;31(2):263-9.
We here report a t(9;11)(p11;q23) as the only abnormality in the affected cells of a 20-year-old male with acute lymphoblastic leukemia (L2) of T-cell origin. One hundred six patients with acute leukemia and involvement of band 11q23 were reviewed. Young age, hyperleukocytosis, and poor prognosis characterized almost all the cases in the acute leukemias with the 11q23 translocation, despite involvement of different recipient chromosomes and different morphologic and immunologic phenotypes.