A morphogen for the sporulation of Physarum polycephalum detected by cell fusion experiments.

Experimental cell research

PubMedID: 3770098

Hildebrandt A. A morphogen for the sporulation of Physarum polycephalum detected by cell fusion experiments. Exp Cell Res. 1986;167(2):453-7.
The light stimulus, which under conditions of starvation induces the development of sporangia in the slime mold Physarum polycephalum, can be transferred from the light-exposed part to the unexposed part of a plasmodium by means of plasma circulation. A small quantity of protoplasm from a sporulating donor plasmodium, which had passed through the premorphogenetic phase, was transferred by a short period fusion with a briefly starved, light-induction-incompetent acceptor plasmodium. This led to sporulation and even to a reduction of the premorphogenetic phase from 9 down to 3 h in the acceptor plasmodium. After fusion with a sporulating plasmodium, a highly starved plasmodium from a non-sporogenic culture line or a growing plasmodium from a normal line prevents further morphogenesis of sporangia in the sporulating partner.