Abortion may sensitize the mother to HLA antigens.

Tissue antigens

PubMedID: 7330843

Gelabert A, Balasch J, Ercilla G, Vanrell JA, Vives J, González-Merlo J, Castillo R. Abortion may sensitize the mother to HLA antigens. Tissue Antigens. 1982;17(4):353-6.
The incidence of cytotoxic antibodies in relation to histories of abortions was analyzed in sera from 474 nulliparous pregnant women. In patients with previous spontaneous abortions, there is a higher incidence of positive sera than in primigravidae. Furthermore, patients with two or more prior abortions show a greater incidence of cytotoxic activity in their sera than women who have had only one abortion.