The Journal of experimental medicine

PubMedID: 19867963

Weil R, Torrey JC. IMMUNOLOGICAL STUDIES IN PNEUMONIA. J Exp Med. 1916;23(1):1-10.
The serum derived from human cases of pneumonia has been used to sensitize guinea pigs passively. As antigen an autolysate of a pneumococcus culture was employed. By means of Dale's method it has been possible to show with considerable regularity that the blood contains sensitizing antibodies during the course of pneumonia, but none after the crisis. Patients suffering from other diseases have failed to give this reaction, as have also normal individuals.