A netlike rolling circle nucleic acid amplification technique.

The Analyst

PubMedID: 25407326

Zhu X, Feng C, Zhang B, Tong H, Gao T, Li G. A netlike rolling circle nucleic acid amplification technique. Analyst. 2014;.
A nucleic acid amplification technique termed as netlike rolling circle amplification is proposed by introducing a nicking enzyme into the existing hyperbranched rolling circle amplification system. Surprisingly dense and uniform network morphology is observed; and cubic amplification is achieved for the sensitive detection of a sequence from HIV.