[Ovarian stem cells- myth or reality?].

Akusherstvo i ginekologiia

PubMedID: 25675620

The main dogma in reproductive medicine claims that ovarian reserve in mammals is formed during prenatal period and the decline in the existing oocyte pool can not be compensated. The thesis that girls are born with a certain number of eggs, which gradually decrease with age, and the ovaries can not produce more reproductive cells was greatly "shaken" during the last decade. Some reports have appeared for the presence of germline stem cells in the adult ovaries and for their capacity to form oocytes in the postnatal period. In this review are provided summarized literature data on this matter.