[A Case of Stage IV Breast Cancer with Improved Cancer Pain Using Bevacizumab and Paclitaxel].

Gan to kagaku ryoho. Cancer & chemotherapy

PubMedID: 25812505

Ishiyama T, Jinguu A, Matsumoto H, Kikuchi J, Suzuki T. [A Case of Stage IV Breast Cancer with Improved Cancer Pain Using Bevacizumab and Paclitaxel]. Gan To Kagaku Ryoho. 2015;42(3):347-9.
A 65-year-old woman with a right breast tumor and right arm pain was seen in our hospital. She was diagnosed with scirrhous carcinoma(Stage IV, hormone receptor-positive, and HER2-negative)with pleural effusion and metastasis to the lung, liver, bone, and multiple lymph nodes. Systemic chemotherapy with biweekly bevacizumab and weekly paclitaxel was administered, and an opioid(oxycodone 40mg/day)was administered for pain control. At the end of the first course, the patient's pain was improved, and the opioid dose was reduced(oxycodone 20mg/day). The patient had a partial response (PR)over 24 treatment courses(1 year 10 months), and good pain control was obtained. Bevacizumab and paclitaxel therapy successfully brought about a rapid and good response and improved the patient's quality of life as palliative chemo- therapy.