Thymic hyperplasia in a patient with Graves' disease.

Zhonghua yi xue za zhi = Chinese medical journal; Free China ed

PubMedID: 11355328

Hsu LH, Chen JC, Tsai GJ, Tsou MH, Hsu WH. Thymic hyperplasia in a patient with Graves' disease. Zhonghua Yi Xue Za Zhi (Taipei). 2001;64(2):115-20.
Hyperplastic changes of the thymus may be found in patients with Graves' disease. However, this rarely presents as an anterior mediastinal mass, particularly among adults. In this report, we describe a 32-year old woman with Graves' disease and hyperthyroidism. During medical evaluation and treatment for her hyperthyroidism, a large anterior mediastinal mass was incidentally discovered. A cytological study of the lesion via computed tomogram-guided fine needle biopsy could not make a definitive diagnosis and suggested the possibility of a thymoma, which led to a surgical exploration. However, the final pathological diagnosis of the surgically removed tissue was thymic hyperplasia. The relationship between Graves' disease and thymic changes is discussed.