Quantitative analysis coupled with toxic evaluation to investigate the influence of sulfur-fumigation on the quality of Chrysanthemum morifolium.

Natural product communications

PubMedID: 25918810

Ding K, Cao G, Xu Z, Chen X. Quantitative analysis coupled with toxic evaluation to investigate the influence of sulfur-fumigation on the quality of Chrysanthemum morifolium. Nat Prod Commun. 2014;9(9):1357-8.
In the present study, quantitative analysis coupled with toxic evaluation was applied to investigate the influence of sulfur-fumigation on the quality of Chrysanthemum morifolium. THE RESULTS
showed that the average contents of six flavonoids (cynaroside, hyperoside, isoquercitrin, luteolin, apigenin, and diosmetin) in sulfur-fumigated C.The results showed that the average contents of six flavonoids (cynaroside, hyperoside, isoquercitrin, luteolin, apigenin, and diosmetin) in sulfur-fumigated C. morifolium samples decreased by about 6. 2%, 3. 5%, 22. 0%, 33. 3%, 26. 0%, and 36. 9%, respectively, while the average contents of two organic acids (chlorogenic acid and isochlorogenic acid A) in sulfur-fumigated C. morifolium samples increased by about 16. 8% and 7. 6%, respectively. Furthermore, high dosage sulfur-fumigated C. morifolium could induce hydropic degeneration in epithelial cells of the renal tubule and interstitial edema. This indicates that sulfur-fumigated C. morifolium may lead to renal toxicity.