Correlates of quality of life in overweight or obese breast cancer survivors at enrollment into a weight loss trial.

Psycho-oncology

PubMedID: 25920528

Pakiz B, Ganz PA, Sedjo RL, Flatt SW, Demark-Wahnefried W, Liu J, Wolin KY, Rock CL. Correlates of quality of life in overweight or obese breast cancer survivors at enrollment into a weight loss trial. Psychooncology. 2015;.
OBJECTIVE
The purpose of this analysis was to examine the correlates of the physical and psychosocial domains of quality of life (QOL) in a cohort of breast cancer survivors participating in a weight loss intervention trial.

METHODS
Correlates of QOL and psychosocial functioning were examined in 692 overweight or obese breast cancer survivors at entry into a weight loss trial. QOL was explored with three measures: Short-form 36 (SF-36), Impact of Cancer scale (IOC), and the Breast Cancer Prevention Trial (BCPT) symptom scales. Available data included information on weight and physical activity, as well as demographic and medical characteristics. Multivariate analyses were used to identify associations adjusted for other characteristics.

RESULTS
In multivariate analysis, younger age was associated with higher negative impact scores (p?
CONCLUSIONS
Quality-of-life measures in breast cancer survivors are differentially associated with demographic and other characteristics. When adjusted for these characteristics, degree of adiposity among overweight or obese women does not appear to be independently associated with QOL. Among overweight or obese breast cancer survivors, higher level of physical activity is associated with higher QOL across various scales and dimensions. Copyright © 2015 John Wiley & Sons, Ltd.