Prospects for enhancement of targeted radionuclide therapy of cancer using ultrasound.

Journal of labelled compounds & radiopharmaceuticals

PubMedID: 24347456

Browning RJ, Rajkumar V, Pedley RB, Eckersley RJ, Blower PJ. Prospects for enhancement of targeted radionuclide therapy of cancer using ultrasound. J Labelled Comp Radiopharm. 2014;57(4):279-84.
Ultrasound-mediated drug delivery is a promising means of enhancing delivery, distribution and effectiveness of drugs within tumours. In this review, prospects for exploiting ultrasound to improve the tumour delivery and distribution of radiolabelled antibodies for radioimmunotherapy and to overcome barriers imposed by tumour microenvironment are discussed.