Mercury and selenium concentrations in skeletal muscle, liver, and regions of the heart and kidney in bearded seals from Alaska, USA.

Environmental toxicology and chemistry / SETAC

PubMedID: 26013477

Correa L, Castellini JM, Quakenbush LT, O'Hara TM. Mercury and selenium concentrations in skeletal muscle, liver, and regions of the heart and kidney in bearded seals from Alaska, USA. Environ Toxicol Chem. 2015;.
Mean concentrations of total mercury ([THg]) and selenium ([TSe]) (mass and molar-based) were determined for 5 regions of the heart and 2 regions of the kidney of bearded seals (Erignathus barbatus) harvested in Alaska, USA, in 2010 and 2011. Mean [THg] and [TSe] of bearded seal liver and skeletal muscle tissues were used for intertissular comparison. The Se:Hg molar ratios were used to investigate elemental associations and potential antioxidant protection against Hg toxicosis. Age was an important factor in [THg] and Se:Hg molar ratios in heart and kidney. Small but statistically significant differences in mean [THg] occurred among some of the 5 heart regions (p < 0. 05). Mean [THg] was highest in liver, 3. 057?µg/g, and lowest in heart left ventricle, 0. 017?µg/g. Mean [THg] ranked: liver > kidney cortex > kidney medulla > skeletal muscle > heart left ventricle (p < 0. 001). Mean [TSe] was highest in liver, 3. 848?µg/g, and lowest in heart left ventricle, 0. 632?µg/g. Mean [TSe] ranked: liver > kidney cortex > kidney medulla > skeletal muscle > heart left ventricle (p < 0. 001). The Se:Hg molar ratios were significantly greater than 1. 0 in all tissues (p < 0. 001) and represented baselines for normal [TSe] under relatively low [THg]. Mean Se:Hg molar ratios ranked: heart left ventricle > kidney medulla > kidney cortex (p < 0. 001). Environ Toxicol Chem 2015;34:2403-2408. © 2015 SETAC.