IGEMS: the consortium on Interplay of Genes and Environment across Multiple Studies.

Twin research and human genetics : the official journal of the International Society for Twin Studies

PubMedID: 23186995

Pedersen NL, Christensen K, Dahl AK, Finkel D, Franz CE, Gatz M, Horwitz BN, Johansson B, Johnson W, Kremen WS, Lyons MJ, Malmberg B, McGue M, Neiderhiser JM, Petersen I, Reynolds CA. IGEMS: the consortium on Interplay of Genes and Environment across Multiple Studies. Twin Res Hum Genet. 2013;16(1):481-9.
The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from over 17,500 participants aged 25-102 at baseline (including nearly 2,600 monogygotic and 4,300 dizygotic twin pairs and over 1,700 family members) aims to understand why early life adversity, and social factors such as isolation and loneliness, are associated with diverse outcomes including mortality, physical functioning (health, functional ability), and psychological functioning (well-being, cognition), particularly in later life.