CT-guided biopsies in lung infections in patients with haematological malignancies.

Diagnostic and interventional imaging

PubMedID: 23352879

de Bazelaire C, Coffin A, Cohen-Zarade S, de Margerie-Mellon C, Scemama A, Sabatier F, Calmon R, de Kerviler E. CT-guided biopsies in lung infections in patients with haematological malignancies. Diagn Interv Imaging. 2013;94(2):202-15.
CT-guided transparietal lung biopsy in imaging makes it possible to find the pathogenic agent in half of all fungal infections and most bacterial infections (sensitivity=55%, specificity=100%). Performance is decreased in consolidations (50% of infections) compared to masses. Complications, pneumothorax, alveolar bleeding and hemoptysis are generally benign and rarely (<5%) require specific treatment. On the other hand, the diagnostic performance increases significantly with the calibre of 18G co-axial systems compared to 20G. The risk is not related to the number of samples or platelet levels.