Thiazolylidene-Catalyzed Cleavage of Methyl Oleate-Derived a-Hydroxy Ketone to the Corresponding Free Aldehydes.

ChemSusChem

PubMedID: 26120006

Deruer E, Duguet N, Lemaire M. Thiazolylidene-Catalyzed Cleavage of Methyl Oleate-Derived a-Hydroxy Ketone to the Corresponding Free Aldehydes. ChemSusChem. 2015;.
The thiazolylidene-catalyzed cleavage of the a-hydroxy ketone derived from methyl oleate gave the corresponding aldehydes under nonoxidative conditions through a retro-benzoin process. The aldehydes produced are in equilibrium with their corresponding acyloins. To illustrate the synthetic utility of this protocol, the aldehydes were recovered by distillation.