[Delayed neurological syndrome following carbon monoxide poisoning].

Revista de neurologia

PubMedID: 26204086

Vazquez-Lima MJ, Alvarez-Rodriguez C, Cruz-Landeira A, Lopez-Rivadulla M. [Delayed neurological syndrome following carbon monoxide poisoning]. Rev Neurol. 2015;61(4):153-8.
INTRODUCTION
Poisoning by carbon monoxide is the most frequent form of intoxication in our milieu as a result of exposure to poisonous gases. The effects of carbon monoxide poisoning are not limited to acute exposure, since, following apparent recovery from the acute intoxication, neurological or behavioural disorders may appear.

PATIENTS AND METHODS
A study was conducted to examine the cases of carbon monoxide poisoning that had occurred in a healthcare area of 80,000 inhabitants over a 10-year period. These patients were then submitted to a follow-up to appraise the appearance of delayed neurological syndrome (DNS) and its relationship with different variables in the initial exposure to the carbon monoxide, in the treatment that was administered or in the severity of the intoxication.

RESULTS AND CONCLUSIONS
It was observed that around 9.1% of those intoxicated by carbon dioxide detected within the healthcare district of Salnes went on to develop DNS, which is more frequent in patients with severe analytical criteria and very unlikely in those who do not have them. Patients with DNS did not express any clinical or analytical manifestations that differed from those who did not have the syndrome; no differences were observed in relation to the oxygen therapy that was administered. The rate of DNS within the healthcare district of Salnes between 2002 and 2012 is 0.84 cases per 100,000 inhabitants per year.