Is It Possible to Perform Less Radical Surgery for Invasive Uterine Cervical Cancer?

Gynecologic and obstetric investigation

PubMedID: 26584181

Togami S, Kamio M, Kobayashi H, Douchi T. Is It Possible to Perform Less Radical Surgery for Invasive Uterine Cervical Cancer?. Gynecol Obstet Invest. 2016;.
BACKGROUND/AIMS
A retrospective analysis was performed to evaluate the possibility of less radical surgery for early-stage invasive uterine cervical cancer without compromising the oncological outcome.

METHODS
The analysis was performed on 175 patients with invasive uterine cervical cancer in FIGO stage IA2-IIB, all of whom underwent primary radical hysterectomy. Relationship of tumor size with the incidence of pathologic parametrial involvement and the pelvic lymph node metastasis were investigated.

RESULTS
Fifty-one patients had tumor size =2 cm and 124 had tumor size >2 cm. Patients with tumor size =2 cm had a significantly lower incidence of parametrial invasion (p < 0.0001), lymph node metastasis (p < 0.0001), lymph vascular space involvement (p < 0.0001) and recurrence (p = 0.0002) than patients with tumor size >2 cm. Five-year relapse-free survival rate was 98 and 73%, respectively (p = 0.0004).

CONCLUSION
It is suggested that less radical surgery may be appropriate for some cases with tumor size <2 cm.