Understanding the Roles of the NF-?B Pathway in Regulatory T Cell Development, Differentiation and Function.

Progress in molecular biology and translational science

PubMedID: 26615092

Fulford TS, Ellis D, Gerondakis S. Understanding the Roles of the NF-?B Pathway in Regulatory T Cell Development, Differentiation and Function. Prog Mol Biol Transl Sci. 2015;13657-67.
The nuclear factor of kappaB (NF-?B) pathway has emerged as an important regulator of gene expression in CD4(+) regulatory T cells. Here, we review various aspects of the roles NF-?B signaling plays in the development and function of Tregs.