Anterior chamber aqueous flare, pseudoexfoliation syndrome, and glaucoma.

International ophthalmology

PubMedID: 26787385

Kahloun R, Attia S, Ksiaa I, Kacem I, Bouanene I, Zaouali S, Jelliti B, Khairallah M. Anterior chamber aqueous flare, pseudoexfoliation syndrome, and glaucoma. Int Ophthalmol. 2016;.
The purpose of this study is to evaluate anterior chamber aqueous flare (ACAF) in Tunisian patients with pseudoexfoliation (PEX) syndrome with or without associated glaucoma. This is a prospective, cross-sectional, comparative study including 53 patients (88 eyes) with PEX syndrome, 48 patients with PEX glaucoma (86 eyes), and 53 healthy sex-and age-matched control subjects (106 eyes). All patients underwent a complete ophthalmic examination and laser flare photometry. Mean ACAF was significantly higher in the PEX syndrome group in comparison with the control group (17. 96 ± 10. 05 vs 7. 06 ± 2. 95 ph/ms; p = 10(-4)), in patients with PEX glaucoma compared to PEX syndrome without associated glaucoma (27. 99 ± 15. 45 vs 17. 96 ± 10. 05 ph/ms; p = 10(-4)), in the PEX glaucoma group in comparison with control group (27. 99 ± 15. 45 vs 7. 06 ± 2. 95 ph/ms; p = 10(-4)), and in patients with unilateral PEX syndrome in comparison with contralateral-unaffected eyes (25. 72 ± 14. 88 vs 8. 58 ± 3. 45 ph/ms; p = 0. 000). For patients with PEX syndrome, a high ACAF might be a predictor for the development of glaucoma. Further investigations are needed to clarify the role of laser flare photometry in predicting the risk of glaucoma in patients with PEX syndrome.