Palladium-Catalyzed Nitration of Meyer-Schuster Intermediates with tBuONO as Nitrogen Source at Ambient Temperature.

Organic letters

PubMedID: 27434133

Lin Y, Kong W, Song Q. Palladium-Catalyzed Nitration of Meyer-Schuster Intermediates with tBuONO as Nitrogen Source at Ambient Temperature. Org Lett. 2016;.
A novel domino palladium-catalyzed nitration of Meyer-Schuster intermediates which were generated in situ from propargylic alcohols was developed, by the use of t-BuONO, leading to a-nitro enones in good to excellent yields at room temperature with a broad functional group tolerance.