Two New Secondary Metabolites from the Endophytic Fungus Endomelanconiopsis endophytica.

Molecules (Basel, Switzerland)

PubMedID: 27447605

Sun ZH, Li HH, Liang FL, Chen YC, Liu HX, Li SN, Tan GH, Zhang WM. Two New Secondary Metabolites from the Endophytic Fungus Endomelanconiopsis endophytica. Molecules. 2016;21(7):.
Two new secondary metabolites, endomeketals A-B (1-2), a new natural product (3), and a known compound (4) were isolated from the ethyl acetate extract of the endophytic fungus Endomelanconiopsis endophytica A326 derived from Ficus hirta. Their structures were determined on the basis of extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities against SF-268, MCF-7, NCI-H460, and HepG-2 tumor cell lines. However, no compound showed cytotoxic activity against these human tumor cell lines.