Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study.

BMC Musculoskeletal Disorders

PubMedID: 27496130

Leu TH, Chang WC, Lin JC, Lo C, Liang WM, Chang YJ, Shih DP, Wu CC, Cheng CF, Wei SJ. Incidence and excess mortality of hip fracture in young adults: a nationwide population-based cohort study. BMC Musculoskelet Disord. 2016;17326.
BACKGROUND
This study assessed the incidence and excess mortality of hip fractures among inpatients aged 20-40 years in a nationwide population database in Taiwan.

METHODS
Subjects were selected from Taiwan's National Health Insurance Research Database for the period 2001-2008 and were followed up until the end of 2010. A total of 4,523 subjects were admitted for the first time with primary diagnosis of hip fracture and treated with operation.

RESULTS
The overall annual incidence, mortality, and standardized mortality ratio (SMR) decreased from 7.68 to 7.23 per 100,000, from 1.37 % to 0.94 %, and from 9.06 to 6.71, respectively, from 2001 to 2008. The 1-year, 2-year, 3-year, 5-year, and 10-year mortality rates were 1.28 %, 2.44 %, 3.54 %, 5.32 %, and 10.50 %, respectively for the whole cohort. The 1-year, 2-year, 3-year, 5-year, and 10-year SMRs were 8.33, 7.59, 7.28, 6.39, and 5.82, respectively, for the whole cohort. Risk factors for overall death were male gender, trochanteric fracture, hemiarthroplasty, and higher Charlson comorbidity index (CCI) scores.

CONCLUSIONS
The high SMRs found in the present study suggest that young adults with former hip fracture should be closely followed up to prevent early mortality.