Respiratory Morbidity in Late-Preterm Births: A Prospective Observational Study at a Tertiary Care Hospital.

Journal of obstetrics and gynaecology of India

PubMedID: 27651621

Shaikh N, Faizi S, Rai L. Respiratory Morbidity in Late-Preterm Births: A Prospective Observational Study at a Tertiary Care Hospital. J Obstet Gynaecol India. 2016;66(Suppl 1):301-6.
OBJECTIVES
To study the neonatal respiratory morbidity in late-preterm neonates.

MATERIALS AND METHODS
This study was done over a period of 6 months (November 2014-April 2015) including 120 late-preterm births at a tertiary referral center.

RESULTS
Among the 120 late-preterm babies, 42 (35 %) developed respiratory morbidity. Respiratory distress syndrome (RDS) developed in 43 % of the babies who had not received steroid prophylaxis against 25.8 % receiving the same (p < 0.05). Among the indicated late-preterm deliveries, 45 % of babies developed respiratory morbidity in comparison with 22 % of the babies born following spontaneous onset of labor (p < 0.05). In the neonates with respiratory morbidity, male babies had a higher incidence than their female counterparts (48 vs. 24 % p < 0.05). Severity of RDS declined from 57 % for babies born at 34 weeks of gestation to 26.3 % for those born at 36 weeks (p 0.14). With each advancing week of gestation a significant reduction in the need for ventilator support (78 % at 34 weeks to 15 % at 36 weeks of gestation p < 0.05) was observed. Presence of antenatal risk factors did not significantly contribute to the respiratory morbidity.

CONCLUSION
The severity of respiratory morbidity and need for ventilator support declines with advancing gestational age; hence, every attempt must be made to prolong pregnancy till 36 weeks of gestation.