The synthesis and characterization N-methyl-3-phenyl-norbornan-2-amine (Camfetamine™).

Drug testing and analysis

PubMedID: 22374810

Kavanagh P, Angelov D, O'Brien J, Power JD, McDermott SD, Talbot B, Fox J, O'Donnell C, Christie R. The synthesis and characterization N-methyl-3-phenyl-norbornan-2-amine (Camfetamine™). Drug Test Anal. 2013;5(4):247-53.
N-Methyl-3-phenyl-norbornan-2-amine (N-methyl-3-phenylbicyclo[2.2.1]heptan-2-amine, Camfetamine(™) ) is available from a number of online legal highs/research chemicals' vendors. Although it was developed as an analeptic by Merck in the early 1960s, it was never commercialized. However, the Association of Independent Research Chemical Retailers (AIRCR), an umbrella organization for a number of online vendors, has redeveloped it for use as a recreational drug. N-Methyl-3-phenyl-norbornan-2-amine is closely related to fencamfamine which has been widely used as a central nervous system (CNS) stimulant and appetite suppressant. In this paper we describe the synthesis of N-methyl-3-phenyl-norbornan-2-amine, its characterization and interpretations of its electron impact, and electrospray ionization mass spectra.