Prognostic Value of Modified Banff Score in the Evolution of Renal Function.

Transplantation proceedings

PubMedID: 27932103

Bancu I, Hernández-Gallego A, López-Alvárez D, Lozano-Ramos I, Cañas-Sole L, Juega-Mariño J, Pérez-Mir M, Borras-Seres F, Bonet-Sol J, Lauzurica R. Prognostic Value of Modified Banff Score in the Evolution of Renal Function. Transplant Proc. 2016;48(9):2903-2905.
BACKGROUND
Some lesions not included in the Banff classification, such as inflammation in the scarred areas and total inflammation, have been described to have prognostic value in the evaluation of graft biopsies. Our aim was to reassess kidney graft biopsies and study the impact of histopathologic lesions, both those graded in the Banff classification and those related to inflammation, on the graft function and evolution.

METHODS
We selected 20 biopsies exhibiting chronic pathology without a specific phenotype, and we reevaluated them with the use of a modified Banff score.

RESULTS
We found statistically significant association between the presence of total inflammation (P = .048; P = .038), the presence of inflammation in scared area (P = .037; P = .018), and creatinine at the time of renal biopsy and 1 year after the renal biopsy, respectively.

CONCLUSIONS
Our results suggest that the presence of both inflammation in the scarred areas and total inflammation are related to renal function at the time of the biopsy and to renal function 1 year after the biopsy.