Association of serum uric acid with high-sensitivity C-reactive protein in postmenopausal women.

Climacteric : the journal of the International Menopause Society

PubMedID: 28105870

Raeisi A, Ostovar A, Vahdat K, Rezaei P, Darabi H, Moshtaghi D, Nabipour I. Association of serum uric acid with high-sensitivity C-reactive protein in postmenopausal women. Climacteric. 2017;20(1):44-48.
OBJECTIVES
To explore the independent correlation between serum uric acid and low-grade inflammation (measured by high-sensitivity C-reactive protein, hs-CRP) in postmenopausal women.

METHODS
A total of 378 healthy Iranian postmenopausal women were randomly selected in a population-based study. Circulating hs-CRP levels were measured by highly specific enzyme-linked immunosorbent assay method and an enzymatic calorimetric method was used to measure serum levels of uric acid. Pearson correlation coefficient, multiple linear regression and logistic regression models were used to analyze the association between uric acid and hs-CRP levels.

RESULTS
A statistically significant correlation was seen between serum levels of uric acid and log-transformed circulating hs-CRP (r?=?0.25, p?
CONCLUSION
Higher serum uric acid levels were positively and independently associated with circulating hs-CRP in healthy postmenopausal women.