Aquagenic pruritus induced by clomipramine.

General hospital psychiatry

PubMedID: 23477795

Mendlowicz MV, Lima JL, Fontenelle LF. Aquagenic pruritus induced by clomipramine. Gen Hosp Psychiatry. 2013;.
OBJECTIVE: Aquagenic pruritus is the development of severe, prickling-like skin discomfort without observable skin lesions that is evoked by contact with water at any temperature. METHOD: This is a case report of a man presenting with aquagenic pruritus after starting clomipramine treatment for anxiety and depression. RESULTS: The patient's aquagenic pruritus resolved after discontinuing the clomipramine but reemerged when treatment was restarted. CONCLUSIONS: A greater awareness and knowledge about aquagenic pruritus among physicians could help improve the clinical recognition and management of this clinical entity.