The effect of topical cyclosporine 0.05% on dry eye after cataract surgery.

Korean journal of ophthalmology : KJO

PubMedID: 23730108

Chung YW, Oh TH, Chung SK. The effect of topical cyclosporine 0.05% on dry eye after cataract surgery. Korean J Ophthalmol. 2013;27(3):167-71.
PURPOSE
To evaluate the effectiveness of cyclosporine 0.05% for dry eye after cataract surgery.

METHODS
Thirty-two newly diagnosed patients with dry eye syndrome 1 week after cataract surgery received a twice-daily treatment of cyclosporine 0.05% for one eye and normal saline 0.9% for the other. Disease severity was measured at 2 weeks, 1 month, 2 months, and 3 months by Schirmer test I (ST-I), tear film break-up time (tBUT), corneal temperature and dry eye symptom questionnaire (Ocular Surface Disease Index).

RESULTS
Both groups increased in ST-I and tBUT over time. ST-I in the cyclosporine 0.05% group showed a significant increase at 3 months and tBUT in the cyclosporine 0.05% group showed an increase at 2 and 3 months. The dry eye symptom score was significantly reduced in the cyclosporine 0.05% group.

CONCLUSIONS
Cyclosporine 0.05% can also be an effective treatment for dry eye after cataract surgery.